-
1
-
-
32344444114
-
“The Ethics and Science of Placebo-Controlled Trials: Assay Sensitivity and the Duhem-quine Thesis.”
-
Anderson, James A. 2006. “The Ethics and Science of Placebo-Controlled Trials: Assay Sensitivity and the Duhem-quine Thesis.” Journal of Medicine and Philosophy(31): 65–81.
-
(2006)
Journal of Medicine and Philosophy
, Issue.31
, pp. 65-81
-
-
Anderson, J.A.1
-
2
-
-
77952844165
-
“Extending Clinical Equipoise to Phase 1 Trials Involving Patients: Unresolved Problems.”
-
Anderson, James A., and Jonathan Kimmelman. 2010. “Extending Clinical Equipoise to Phase 1 Trials Involving Patients: Unresolved Problems.” Kennedy Institute of Ethics Journal20 (1): 75–98.
-
(2010)
Kennedy Institute of Ethics Journal
, vol.20
, Issue.1
, pp. 75-98
-
-
Anderson, J.A.1
Kimmelman, J.2
-
4
-
-
34147096350
-
“Lessons from the Vioxx Debacle: What the Privatization of Science Can Teach Us about Social Epistemology.”
-
Biddle, Justin. 2007. “Lessons from the Vioxx Debacle: What the Privatization of Science Can Teach Us about Social Epistemology.” Social Epistemology21 (1): 21–39.
-
(2007)
Social Epistemology
, vol.21
, Issue.1
, pp. 21-39
-
-
Biddle, J.1
-
5
-
-
84863505612
-
“Amending and Defending Critical Contextual Empiricism.”
-
Borgerson, Kirstin. 2011. “Amending and Defending Critical Contextual Empiricism.” European Journal for Philosophy of Science1 (3): 435–49.
-
(2011)
European Journal for Philosophy of Science
, vol.1
, Issue.3
, pp. 435-449
-
-
Borgerson, K.1
-
6
-
-
84881185785
-
“Are Explanatory Trials Ethical? Shifting the burden of Justification in Clinical Trial Design.”
-
Borgerson, Kirstin. 2013. “Are Explanatory Trials Ethical? Shifting the burden of Justification in Clinical Trial Design.” Theoretical Medicine and Bioethics34 (4): 293–308.
-
(2013)
Theoretical Medicine and Bioethics
, vol.34
, Issue.4
, pp. 293-308
-
-
Borgerson, K.1
-
7
-
-
84860444921
-
“Characteristics of Clinical Trials Registered in ClinicalTrials.Gov, 2007–2010.”
-
Califf, Robert M., Deborah A. Zarin, Judith M. Kramer, Rachel E. Sherman, Laura H. Aberle, and Asba Tasneem. 2012. “Characteristics of Clinical Trials Registered in ClinicalTrials.gov, 2007–2010.” Journal of the American Medical Association307 (17): 1838–47.
-
(2012)
Journal of the American Medical Association
, vol.307
, Issue.17
, pp. 1838-1847
-
-
Califf, R.M.1
Zarin, D.A.2
Kramer, J.M.3
Sherman, R.E.4
Aberle, L.H.5
Tasneem, A.6
-
8
-
-
21344474046
-
“The Scandalous Failure of Science to Cumulative Evidence Scientifically.”
-
Chalmers, Iain. 2005. “The Scandalous Failure of Science to Cumulative Evidence Scientifically.” Clinical Trials(2): 229–31.
-
(2005)
Clinical Trials
, Issue.2
, pp. 229-231
-
-
Chalmers, I.1
-
9
-
-
53349176071
-
“The lethal Consequences of Failing To make Full Use of All Relevant Evidence About Effects of medical Treatments: The Importance of Systematic Reviews.”
-
edited by Peter Rothwell, London: Lancet
-
Chalmers, Iain. 2007a. “The lethal Consequences of Failing To make Full Use of All Relevant Evidence About Effects of medical Treatments: The Importance of Systematic Reviews.” In Treating Individuals: From Randomized Trials to Personalized Medicine, edited by Peter Rothwell, 37–58. London: Lancet.
-
(2007)
Treating Individuals: From Randomized Trials to Personalized Medicine
, pp. 37-58
-
-
Chalmers, I.1
-
10
-
-
36348929302
-
“Regulation of Therapeutic Research Is Compromising the Interests of Patients.”
-
Chalmers, Iain. 2007b. “Regulation of Therapeutic Research Is Compromising the Interests of Patients.” International Journal of Pharmaceutical Medicine(21): 395–404.
-
(2007)
International Journal of Pharmaceutical Medicine
, Issue.21
, pp. 395-404
-
-
Chalmers, I.1
-
11
-
-
67649649676
-
“Avoidable Waste in the Production and Reporting of Research Evidence.”
-
Chalmers, Iain, and Paul Glasziou. 2009. “Avoidable Waste in the Production and Reporting of Research Evidence.” The Lancet374: 86–89.
-
(2009)
The Lancet
, vol.374
, pp. 86-89
-
-
Chalmers, I.1
Glasziou, P.2
-
12
-
-
84872292655
-
“All Trials must be Registered and the Results Published.”
-
Chalmers, Iain, Paul Glasziou, and Fiona Godlee. 2013. “All Trials must be Registered and the Results Published.” BMJ346: f105.
-
(2013)
BMJ
, vol.346
-
-
Chalmers, I.1
Glasziou, P.2
Godlee, F.3
-
14
-
-
33947212751
-
“Contesting the Science/Ethics Distinction in the Review of Clinical Research.”
-
Dawson, Angus J., and Steve M. Yentis. 2007. “Contesting the Science/Ethics Distinction in the Review of Clinical Research.” Journal of Medical Ethics(33): 165–67.
-
(2007)
Journal of Medical Ethics
, Issue.33
, pp. 165-167
-
-
Dawson, A.J.1
Yentis, S.M.2
-
15
-
-
84860458009
-
“The Evolution of Trial Registries and Their Use To Assess the Clinical Trial Enterprise.”
-
Dickersin, Kay, and Drummond Rennie. 2012. “The Evolution of Trial Registries and Their Use To Assess the Clinical Trial Enterprise.” Journal of the American Medical Association307 (17): 1861–64.
-
(2012)
Journal of the American Medical Association
, vol.307
, Issue.17
, pp. 1861-1864
-
-
Dickersin, K.1
Rennie, D.2
-
16
-
-
84862731872
-
“Drug Data Shouldn’t be Secret.”
-
April 10
-
Doshi, Peter, and Tom Jefferson. 2012. “Drug Data Shouldn’t be Secret.” New York Times, April 10. http://www.nytimes.com/2012/04/11/opinion/drug-data-shouldnt-be-secret.html?_r=1&.
-
(2012)
New York Times
-
-
Doshi, P.1
Jefferson, T.2
-
17
-
-
84860213443
-
“The Imperative to Share Clinical Study Reports: Recommendations from the Tamifu Experience.”
-
Mar
-
Doshi, Peter, Tom Jefferson, and Chris Del Mar. 2012. “The Imperative to Share Clinical Study Reports: Recommendations from the Tamifu Experience.” PLoS Med 9 (4): e1001201. doi:10.1371/journal.pmed.1001201
-
(2012)
Plos Med
, vol.9
, Issue.4
-
-
Doshi, P.1
Jefferson, T.2
Del, C.3
-
18
-
-
67449157260
-
“The Declaration of Helsinki Through a Feminist lens.”
-
Eckenwiler, Lisa, Dafna Feinholz, Carolyn Ells, and Toby Schonfeld. 2008. “The Declaration of Helsinki Through a Feminist lens.” The International Journal of Feminist Approaches to Bioethics1 (1): 161–77.
-
(2008)
The International Journal of Feminist Approaches to Bioethics
, vol.1
, Issue.1
, pp. 161-177
-
-
Eckenwiler, L.1
Feinholz, D.2
Ells, C.3
Schonfeld, T.4
-
20
-
-
77953394896
-
“In Defense of Valid Design as a Policy Rule.”
-
Evans, Emily L. 2010. “In Defense of Valid Design as a Policy Rule.” The American Journal of Bioethics10 (6): 18–19.
-
(2010)
The American Journal of Bioethics
, vol.10
, Issue.6
, pp. 18-19
-
-
Evans, E.L.1
-
21
-
-
0023452835
-
“Scientific Value and Validity as Ethical Requirements for Research: A Proposed Explication.”
-
Freedman, Benjamin. 1987. “Scientific Value and Validity as Ethical Requirements for Research: A Proposed Explication.” IRB: Ethics and Human Research(9): 7–10.
-
(1987)
IRB: Ethics and Human Research
, Issue.9
, pp. 7-10
-
-
Freedman, B.1
-
26
-
-
70449589963
-
“Questioning the methodological Superiority of ‘Placebo’ over ‘Active’ Controlled Trials.”
-
Howick, Jeremy. 2009. “Questioning the methodological Superiority of ‘Placebo’ over ‘Active’ Controlled Trials.” American Journal of Bioethics9: 34–48.
-
(2009)
American Journal of Bioethics
, vol.9
, pp. 34-48
-
-
Howick, J.1
-
27
-
-
84868669506
-
“(Meta)analyze This: Systematic Reviews might lose Credibility.”
-
Humaidan, Peter, and Nikolaos P. Polyzos. 2012. “(Meta)analyze This: Systematic Reviews might lose Credibility.” Nature Medicine18 (9): 1321.
-
(2012)
Nature Medicine
, vol.18
, Issue.9
, pp. 1321
-
-
Humaidan, P.1
Polyzos, N.P.2
-
28
-
-
84878801000
-
“Extent and Reporting of Patient Non-Enrollment in Influential Randomized Clinical Trials, 2002 to 2010.”
-
Humphreys, Keith, Natalya C. Miasel, Janet C. Blodgett, Ingrid L. Fuh, and John W. Finney. 2013. “Extent and Reporting of Patient Non-Enrollment in Influential Randomized Clinical Trials, 2002 to 2010.” Journal of the American Medical Association: Internal Medicine. doi:10.1001/jamain-ternmed.2013.496.
-
(2013)
Journal of the American Medical Association: Internal Medicine
-
-
Humphreys, K.1
Miasel, N.C.2
Blodgett, J.C.3
Fuh, I.L.4
Finney, J.W.5
-
29
-
-
0037032394
-
“Letter to The Editor: The Ethics of Underpowered Clinical Trials.”
-
Hughes, J. R. 2002. “Letter to The Editor: The Ethics of Underpowered Clinical Trials.” Journal of the American Medical Association288: 2118.
-
(2002)
Journal of the American Medical Association
, vol.288
, pp. 2118
-
-
Hughes, J.R.1
-
31
-
-
0037032394
-
“Letter to the Editor: The Ethics of Underpowered Clinical Trials.”
-
Janosky, J. E. 2002. “Letter to the Editor: The Ethics of Underpowered Clinical Trials.” Journal of the American Medical Association288: 2118.
-
(2002)
Journal of the American Medical Association
, vol.288
, pp. 2118
-
-
Janosky, J.E.1
-
32
-
-
84861998609
-
“Should Preclinical Studies be Registered?”
-
Kimmelman, Jonathan, and James A. Anderson. 2012. “Should Preclinical Studies be Registered?” Nature Biotechnology30 (6): 488–89.
-
(2012)
Nature Biotechnology
, vol.30
, Issue.6
, pp. 488-489
-
-
Kimmelman, J.1
Anderson, J.A.2
-
34
-
-
0038439242
-
“Pharmaceutical Industry Sponsorship and Research Outcome and quality: Systematic Review.”
-
Lexchin, Joel, Lisa A. Bero, Benjamin Djulbegovic, and Otavio Clark. 2003. “Pharmaceutical Industry Sponsorship and Research Outcome and quality: Systematic Review.” BMJ326: 1167.
-
(2003)
BMJ
, vol.326
, pp. 1167
-
-
Lexchin, J.1
Bero, L.A.2
Djulbegovic, B.3
Clark, O.4
-
36
-
-
0345217948
-
-
Princeton: Princeton University Press
-
Longino, Helen. 2002. The Fate of Knowledge. Princeton: Princeton University Press.
-
(2002)
The Fate of Knowledge
-
-
Longino, H.1
-
37
-
-
0003392972
-
-
Washington, DC: Department of Health, Education, and Welfare
-
NCPHS (National Commission for the Protection of Human Subjects of biomedi-cal and behavioral Research). 1979. The Belmont Report: Ethical Principles and Guidelines for the Protection of Human Subjects of Research. Washington, DC: Department of Health, Education, and Welfare. http://www.hhs.gov/ohrp/humansubjects/guidance/belmont.html.
-
(1979)
The Belmont Report: Ethical Principles and Guidelines for the Protection of Human Subjects of Research
-
-
-
40
-
-
78650214800
-
“In Favour of a millian Proposal to Reform biomedical Research.”
-
Reiss, Julian. 2010. “In Favour of a millian Proposal to Reform biomedical Research.” Synthese177: 427–47.
-
(2010)
Synthese
, vol.177
, pp. 427-447
-
-
Reiss, J.1
-
41
-
-
79551611126
-
“A Systematic Examination of the Citation of Prior Research in Reports of Randomized, Controlled Trials.”
-
Robinson, Karen A., and Steven N. Goodman. 2011. “A Systematic Examination of the Citation of Prior Research in Reports of Randomized, Controlled Trials.” Annals of Internal Medicine154: 50–55.
-
(2011)
Annals of Internal Medicine
, vol.154
, pp. 50-55
-
-
Robinson, K.A.1
Goodman, S.N.2
-
42
-
-
80053302427
-
“Disclosure of Clinical Trial Results When Product Development Is Abandoned.”
-
Rogawski, M. A., and H. J. Federoff, “Disclosure of Clinical Trial Results When Product Development Is Abandoned.” Science Translational Medicine3, 102–29 (2011). doi: 10.1126/scitranslmed.3002939
-
(2011)
Science Translational Medicine
, vol.3
, pp. 102-129
-
-
Rogawski, M.A.1
Federoff, H.J.2
-
43
-
-
6044221088
-
“Can Underpowered Clinical Trials be Justified?”
-
Rosoff, Philip M. 2004. “Can Underpowered Clinical Trials be Justified?” IRB: A Review of Human Subjects Research26: 16–19.
-
(2004)
IRB: A Review of Human Subjects Research
, vol.26
, pp. 16-19
-
-
Rosoff, P.M.1
-
44
-
-
77953389362
-
“Response to Open Peer Commentaries on ‘The Case for Evidence-based Rulemaking’.”
-
Sachs, Benjamin. 2010. “Response to Open Peer Commentaries on ‘The Case for Evidence-based Rulemaking’.” The American Journal of Bioethics10 (6): W1–W3.
-
(2010)
The American Journal of Bioethics
, vol.10
, Issue.6
, pp. W1-W3
-
-
Sachs, B.1
-
45
-
-
0036181962
-
“Two Deaths and Two lessons: Is It Time to Review the Structure and Function of Research Ethics Committees?”
-
Savulescu, Julian. 2002. “Two Deaths and Two lessons: Is It Time to Review the Structure and Function of Research Ethics Committees?” Journal of Medical Ethics28: 1–2.
-
(2002)
Journal of Medical Ethics
, vol.28
, pp. 1-2
-
-
Savulescu, J.1
-
46
-
-
0029848062
-
“Are Research Ethics Committees behaving Unethically? Some Suggestions for Improving Performance and Accountability.”
-
Savulescu, Julian, Iain Chalmers, and Jennifer Blunt. 1996. “Are Research Ethics Committees behaving Unethically? Some Suggestions for Improving Performance and Accountability.” BMJ313: 1390–93.
-
(1996)
BMJ
, vol.313
, pp. 1390-1393
-
-
Savulescu, J.1
Chalmers, I.2
Blunt, J.3
-
47
-
-
0036178498
-
“The Hexamenthonium Asthma Study and The Death of a Normal Volunteer in Research.”
-
Savulescu, Julian, and Merle Spriggs. 2002. “The Hexamenthonium Asthma Study and The Death of a Normal Volunteer in Research.” Journal of Medical Ethics28: 3–4.
-
(2002)
Journal of Medical Ethics
, vol.28
, pp. 3-4
-
-
Savulescu, J.1
Spriggs, M.2
-
48
-
-
84892838154
-
“The Case against Ethics Review in the Social Sciences.”
-
Schrag, Zachary M. 2011. “The Case against Ethics Review in the Social Sciences.” Research Ethics7: 120–31.
-
(2011)
Research Ethics
, vol.7
, pp. 120-131
-
-
Schrag, Z.M.1
-
50
-
-
0023008125
-
“Publication bias: The Case for an International Registry of Clinical Trials.”
-
Simes, Robert J. 1986. “Publication bias: The Case for an International Registry of Clinical Trials.” Journal of Clinical Oncology4 (10): 1529–41.
-
(1986)
Journal of Clinical Oncology
, vol.4
, Issue.10
, pp. 1529-1541
-
-
Simes, R.J.1
-
51
-
-
77955990707
-
“Publication Ethics and the Ghost management of medical Publications.”
-
Sismondo, Sergio, and Mathieu Doucet. 2010. “Publication Ethics and the Ghost management of medical Publications.” Bioethics24 (6): 273–83.
-
(2010)
Bioethics
, vol.24
, Issue.6
, pp. 273-283
-
-
Sismondo, S.1
Doucet, M.2
-
52
-
-
72849132173
-
“Dissemination and Publication of Research Findings: An Updated Review of Related biases.”
-
Song, F., S. Parekh, and L. Hooper, et al. 2010. “Dissemination and Publication of Research Findings: An Updated Review of Related biases.” Health Technology Access14 (8). doi:10.3310/hta14080.
-
(2010)
Health Technology Access
, vol.14
, Issue.8
-
-
Song, F.1
Parekh, S.2
Hooper, L.3
-
54
-
-
84859517950
-
-
TCPS-2 (Canadian Institutes of Health Research, Natural Sciences and Engineering Research Council of Canada, and Social Science and Humanities Research Council of Canada), Accessed October 24, 2011
-
TCPS-2 (Canadian Institutes of Health Research, Natural Sciences and Engineering Research Council of Canada, and Social Science and Humanities Research Council of Canada). 2010. Tri-Council Policy Statement: Ethical Conduct for Research Involving Humans. http://www.pre.ethics.gc.ca/eng/policy-politique/initiatives/tcps2-eptc2/Default/. Accessed October 24, 2011.
-
(2010)
Tri-Council Policy Statement: Ethical Conduct for Research Involving Humans
-
-
-
55
-
-
84920183264
-
“Are Researchers Cherry Picking Participants for Studies of Antidepressants?”
-
April 29
-
University of Pittsburgh Schools of the Health Sciences. 2009. “Are Researchers Cherry Picking Participants for Studies of Antidepressants?” ScienceDaily, April 29. www.sciencedaily.com/releases/2009/04/090428103108.htm.
-
(2009)
Sciencedaily
-
-
-
56
-
-
66149184436
-
“Can Phase III Trial Results of Antidepressant medications be Generalized to Clinical Practice? A STAR*D Report.”
-
Wisniewski, Stephen, A. Rush, Andrew Nierenberg, et al. 2009. “Can Phase III Trial Results of Antidepressant medications be Generalized to Clinical Practice? A STAR*D Report.” American Journal of Psychiatry166: 599–607.
-
(2009)
American Journal of Psychiatry
, vol.166
, pp. 599-607
-
-
Wisniewski, S.1
Rush, A.2
Nierenberg, R.3
|