Enzymatic characterization of ELOVL1, a key enzyme in very long-chain fatty acid synthesis

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1851, Issue 2, 2015, Pages 231-237

  Schackmann, Martin J A ^a   Ofman, Rob ^a   Dijkstra, Inge M E ^a   Wanders, Ronald J A ^a   Kemp, Stephan ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

Adrenoleukodystrophy; Fatty acids; Fibrates; Peroxisome; Substrate reduction

Indexed keywords

ACYL COENZYME A; BEZAFIBRATE; CLOFIBRIC ACID; ELOVL1 ENZYME; ENZYME; FENOFIBRATE; FIBRIC ACID DERIVATIVE; GEMFIBROZIL; MALONYL COENZYME A; UNCLASSIFIED DRUG; VERY LONG CHAIN FATTY ACID; ACYLTRANSFERASE; ANTILIPEMIC AGENT; ENZYME INHIBITOR; FATTY ACID; FATTY ACID ELONGASES;

ADRENOLEUKODYSTROPHY; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME KINETICS; FATTY ACID SYNTHESIS; HEK293 CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; INHIBITION CONSTANT; INHIBITION KINETICS; MALE; MICHAELIS MENTEN KINETICS; MICROSOME; OPEN READING FRAME; PEROXISOME; PROTEIN EXPRESSION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SKIN FIBROBLAST; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; DRUG EFFECTS; ENZYMOLOGY; FIBROBLAST; GENETIC TRANSFECTION; GENETICS; KINETICS; METABOLISM;

ACETYLTRANSFERASES; ADRENOLEUKODYSTROPHY; BEZAFIBRATE; ENZYME INHIBITORS; FATTY ACIDS; FIBROBLASTS; GEMFIBROZIL; HEK293 CELLS; HUMANS; HYPOLIPIDEMIC AGENTS; KINETICS; MICROSOMES; TRANSFECTION;

EID: 84920102189     PISSN: 13881981     EISSN: 18792618     Source Type: Journal    
DOI: 10.1016/j.bbalip.2014.12.005     Document Type: Article

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