-
1
-
-
0002921521
-
Nova trypanozomiaze humana: Estudos sobre a morfolojia e o ciclo evolutivo do Schizotrypanum cruzi n. Gen., sp., ajente etiolojico de nova entidade morbida do homem
-
Chagas C. Nova trypanozomiaze humana: estudos sobre a morfolojia e o ciclo evolutivo do Schizotrypanum cruzi n. gen., sp., ajente etiolojico de nova entidade morbida do homem. Mem. Inst. Oswaldo Cruz. 1909 ; 1: 159-218
-
(1909)
Mem. Inst. Oswaldo Cruz
, vol.1
, pp. 159-218
-
-
Chagas, C.1
-
3
-
-
77954187759
-
Chagas Disease: A New Worldwide Challenge
-
Coura J. R., Vinas P. A.. Chagas Disease: A New Worldwide Challenge. Nature. 2010 ; 465: S6 - S7
-
(2010)
Nature
, vol.465
, pp. 6-S7
-
-
Coura, J.R.1
Vinas, P.A.2
-
5
-
-
70149108335
-
An Estimate of the Burden of Chagas Disease in the United States
-
Bern C., Montgomery S. P.. An Estimate of the Burden of Chagas Disease in the United States. Clin. Infect. Dis. 2009 ; 49: e52 - e54
-
(2009)
Clin. Infect. Dis
, vol.49
, pp. 52-e54
-
-
Bern, C.1
Montgomery, S.P.2
-
7
-
-
80054781996
-
Side Effects of Benznidazole Treatment in a Cohort of Patients with Chagas Disease in Non-Endemic Country
-
Carrilero B., Murcia L., Martinez-Lage L., et al. Side Effects of Benznidazole Treatment in a Cohort of Patients with Chagas Disease in Non-Endemic Country. Rev. Esp. Quimioter. 2011 ; 24: 123-126
-
(2011)
Rev. Esp. Quimioter
, vol.24
, pp. 123-126
-
-
Carrilero, B.1
Murcia, L.2
Martinez-Lage, L.3
-
8
-
-
0024020604
-
Toxic Effects of Nifurtimox and Benznidazole, Two Drugs Used against American Trypanosomiasis (Chagas' Disease)
-
Castro J. A., Diaz de Toranzo E. G.. Toxic Effects of Nifurtimox and Benznidazole, Two Drugs Used against American Trypanosomiasis (Chagas' Disease). Biomed. Environ. Sci. 1988 ; 1: 19-33
-
(1988)
Biomed. Environ. Sci
, vol.1
, pp. 19-33
-
-
Castro, J.A.1
Diaz De Toranzo, E.G.2
-
10
-
-
64049108552
-
Side Effects of Benznidazole as Treatment in Chronic Chagas Disease: Fears and Realities
-
Viotti R., Vigliano C., Lococo B., et al. Side Effects of Benznidazole as Treatment in Chronic Chagas Disease: Fears and Realities. Expert Rev. Anti Infect. Ther. 2009 ; 7: 157-163
-
(2009)
Expert Rev. Anti Infect. Ther
, vol.7
, pp. 157-163
-
-
Viotti, R.1
Vigliano, C.2
Lococo, B.3
-
11
-
-
84900311830
-
Randomized Trial of Posaconazole and Benznidazole for Chronic Chagas' Disease
-
Molina I., Gomez i, Prat J., Salvador F., et al. Randomized Trial of Posaconazole and Benznidazole for Chronic Chagas' Disease. N. Engl. J. Med. 2014 ; 370: 1899-1908
-
(2014)
N. Engl. J. Med
, vol.370
, pp. 1899-1908
-
-
Molina, I.1
Gomez, I.2
Prat, J.3
Salvador, F.4
-
13
-
-
84887379124
-
Mapping of Available Health Research and Development Data: What's There, What's Missing, and What Role Is There for a Global Observatory?
-
Rottingen J. A., Regmi S., Eide M., et al. Mapping of Available Health Research and Development Data: What's There, What's Missing, and What Role Is There for a Global Observatory?. Lancet. 2013 ; 382: 1286-1307
-
(2013)
Lancet
, vol.382
, pp. 1286-1307
-
-
Rottingen, J.A.1
Regmi, S.2
Eide, M.3
-
14
-
-
23844534048
-
Drug Discovery and Beyond: The Role of Public-Private Partnerships in Improving Access to New Malaria Medicines 2005
-
Nwaka S.. Drug Discovery and Beyond: The Role of Public-Private Partnerships in Improving Access to New Malaria Medicines 2005. Trans. R. Soc. Trop. Med. Hyg 99.: S20 - S29
-
Trans. R. Soc. Trop. Med. Hyg 99
, pp. 20-S29
-
-
Nwaka, S.1
-
16
-
-
1242330494
-
Engaging Biotechnology Companies in the Development of Innovative Solutions for Diseases of Poverty
-
Kettler H. E., Marjanovic S.. Engaging Biotechnology Companies in the Development of Innovative Solutions for Diseases of Poverty. Nat. Rev. Drug Discov. 2004 ; 3: 171-176
-
(2004)
Nat. Rev. Drug Discov
, vol.3
, pp. 171-176
-
-
Kettler, H.E.1
Marjanovic, S.2
-
17
-
-
79952967329
-
Drug Discovery and Development for Neglected Diseases: The DNDi Model
-
Chatelain E., Ioset J. R.. Drug Discovery and Development for Neglected Diseases: The DNDi Model. Drug Des. Dev. Ther. 2011 ; 5: 175-181
-
(2011)
Drug Des. Dev. Ther
, vol.5
, pp. 175-181
-
-
Chatelain, E.1
Ioset, J.R.2
-
19
-
-
0023804393
-
Comparative Studies of Drug Susceptibility of Five Strains of Trypanosoma cruzi in Vivo and in Vitro
-
Neal R. A., van Bueren J.. Comparative Studies of Drug Susceptibility of Five Strains of Trypanosoma cruzi In Vivo and In Vitro. Trans. R. Soc. Trop. Med. Hyg. 1988 ; 82: 709-714
-
(1988)
Trans. R. Soc. Trop. Med. Hyg
, vol.82
, pp. 709-714
-
-
Neal, R.A.1
Van Bueren, J.2
-
20
-
-
84898824975
-
Nitroheterocyclic Compounds Are More Efficacious Than CYP51 Inhibitors against Trypanosoma cruzi: Implications for Chagas Disease Drug Discovery and Development
-
Moraes C. B., Giardini M. A., Kim H., et al. Nitroheterocyclic Compounds Are More Efficacious Than CYP51 Inhibitors against Trypanosoma cruzi: Implications for Chagas Disease Drug Discovery and Development. Sci. Rep. 2014 ; 4: 4703
-
(2014)
Sci. Rep
, vol.4
, pp. 4703
-
-
Moraes, C.B.1
Giardini, M.A.2
Kim, H.3
-
22
-
-
0021951909
-
Trypanosoma cruzi: Biological Characterization of Clones Derived from Chronic Chagasic Patients: II. Quantitative Analysis of the Intracellular Cycle
-
Engel J. C., Doyle P. S., Dvorak J. A.. Trypanosoma cruzi: Biological Characterization of Clones Derived from Chronic Chagasic Patients: II. Quantitative Analysis of the Intracellular Cycle. J. Protozool. 1985 ; 32: 80-83
-
(1985)
J. Protozool
, vol.32
, pp. 80-83
-
-
Engel, J.C.1
Doyle, P.S.2
Dvorak, J.A.3
-
23
-
-
77957157882
-
In Vitro and in Vivo High-Throughput Assays for the Testing of anti-Trypanosoma cruzi Compounds
-
Canavaci A. M., Bustamante J. M., Padilla A. M., et al. In Vitro and In Vivo High-Throughput Assays for the Testing of anti-Trypanosoma cruzi Compounds. PLoS Negl. Trop. Dis. 2010 ; 4: e740
-
(2010)
PLoS Negl. Trop. Dis
, vol.4
, pp. 740
-
-
Canavaci, A.M.1
Bustamante, J.M.2
Padilla, A.M.3
-
24
-
-
0029861640
-
Efficient Technique for Screening Drugs for Activity against Trypanosoma cruzi Using Parasites Expressing Beta-Galactosidase
-
Buckner F. S., Verlinde C. L., La Flamme A. C., et al. Efficient Technique for Screening Drugs for Activity against Trypanosoma cruzi Using Parasites Expressing Beta-Galactosidase. Antimicrob. Agents Chemother. 1996 ; 40: 2592-2597
-
(1996)
Antimicrob. Agents Chemother
, vol.40
, pp. 2592-2597
-
-
Buckner, F.S.1
Verlinde, C.L.2
La Flamme, A.C.3
-
25
-
-
0035076959
-
Potent Anti-Trypanosoma cruzi Activities of Oxidosqualene Cyclase Inhibitors
-
Buckner F. S., Griffin J. H., Wilson A. J., et al. Potent Anti-Trypanosoma cruzi Activities of Oxidosqualene Cyclase Inhibitors. Antimicrob. Agents Chemother. 2001 ; 45: 1210-1215
-
(2001)
Antimicrob. Agents Chemother
, vol.45
, pp. 1210-1215
-
-
Buckner, F.S.1
Griffin, J.H.2
Wilson, A.J.3
-
26
-
-
84871928568
-
A Modern in Vivo Pharmacokinetic Paradigm: Combining Snapshot, Rapid and Full PK Approaches to Optimize and Expedite Early Drug Discovery
-
Li C., Liu B., Chang J., et al. A Modern In Vivo Pharmacokinetic Paradigm: Combining Snapshot, Rapid and Full PK Approaches to Optimize and Expedite Early Drug Discovery. Drug Discov. Today. 2013 ; 18: 71-78
-
(2013)
Drug Discov. Today
, vol.18
, pp. 71-78
-
-
Li, C.1
Liu, B.2
Chang, J.3
-
27
-
-
77953303004
-
Towards Prediction of in Vivo Intestinal Absorption Using a 96-Well Caco-2 Assay
-
Skolnik S., Lin X., Wang J., et al. Towards Prediction of In Vivo Intestinal Absorption Using a 96-Well Caco-2 Assay. J. Pharm. Sci. 2010 ; 99: 3246-3265
-
(2010)
J. Pharm. Sci
, vol.99
, pp. 3246-3265
-
-
Skolnik, S.1
Lin, X.2
Wang, J.3
-
28
-
-
19344364710
-
Development and Application of High Throughput Plasma Stability Assay for Drug Discovery
-
Di L., Kerns E. H., Hong Y., et al. Development and Application of High Throughput Plasma Stability Assay for Drug Discovery. Int. J. Pharm. 2005 ; 297: 110-119
-
(2005)
Int. J. Pharm
, vol.297
, pp. 110-119
-
-
Di, L.1
Kerns, E.H.2
Hong, Y.3
-
29
-
-
77955402138
-
Image-Based High-Throughput Drug Screening Targeting the Intracellular Stage of Trypanosoma cruzi, the Agent of Chagas' Disease
-
Engel J. C., Ang K. K., Chen S., et al. Image-Based High-Throughput Drug Screening Targeting the Intracellular Stage of Trypanosoma cruzi, the Agent of Chagas' Disease. Antimicrob. Agents Chemother. 2010 ; 54: 3326-3334
-
(2010)
Antimicrob. Agents Chemother
, vol.54
, pp. 3326-3334
-
-
Engel, J.C.1
Ang, K.K.2
Chen, S.3
-
30
-
-
84891291234
-
Two Analogues of Fenarimol Show Curative Activity in an Experimental Model of Chagas Disease
-
Keenan M., Chaplin J. H., Alexander P. W., et al. Two Analogues of Fenarimol Show Curative Activity in an Experimental Model of Chagas Disease. J. Med. Chem. 2013 ; 56: 10158-10170
-
(2013)
J. Med. Chem
, vol.56
, pp. 10158-10170
-
-
Keenan, M.1
Chaplin, J.H.2
Alexander, P.W.3
-
31
-
-
0032881380
-
Effect of Antibiotic Concentration on the Killing of Staphylococcus aureus and Enterococcus faecalis: Comparison of the Novel Penem, Men 10700, with Other Beta-Lactam Antibiotics
-
Hamilton-Miller J. M., Shah S.. Effect of Antibiotic Concentration on the Killing of Staphylococcus aureus and Enterococcus faecalis: Comparison of the Novel Penem, Men 10700, with Other Beta-Lactam Antibiotics. J. Antimicrob. Chemother. 1999 ; 44: 418-420
-
(1999)
J. Antimicrob. Chemother
, vol.44
, pp. 418-420
-
-
Hamilton-Miller, J.M.1
Shah, S.2
-
32
-
-
0023786989
-
The Eagle Effect Revisited: Efficacy of Clindamycin, Erythromycin, and Penicillin in the Treatment of Streptococcal Myositis
-
Stevens D. L., Gibbons A. E., Bergstrom R., et al. The Eagle Effect Revisited: Efficacy of Clindamycin, Erythromycin, and Penicillin in the Treatment of Streptococcal Myositis. J. Infect. Dis. 1988 ; 158: 23-28
-
(1988)
J. Infect. Dis
, vol.158
, pp. 23-28
-
-
Stevens, D.L.1
Gibbons, A.E.2
Bergstrom, R.3
-
34
-
-
84891760956
-
Data, Information, Knowledge and Principle: Back to Metabolism in KEGG
-
Kanehisa M., Goto S., Sato Y., et al. Data, Information, Knowledge and Principle: Back to Metabolism in KEGG. Nucleic Acids Res. 2014 ; 42: D199 - D205
-
(2014)
Nucleic Acids Res
, vol.42
, pp. 199-D205
-
-
Kanehisa, M.1
Goto, S.2
Sato, Y.3
|