Features of endothelial dysfunction in umbilical cord vessels of women with gestational diabetes

Nutrition, Metabolism and Cardiovascular Diseases

Volumn 24, Issue 12, 2014, Pages 1337-1345

  Di Fulvio, P ^a,b   Pandolfi, A ^a   Formoso, G ^a,b   Di Silvestre, S ^a   Di Tomo, P ^a   Giardinelli, A ^a   De Marco, A ^a   Di Pietro, N ^a   Taraborrelli, M ^a,b   Sancilio, S ^a   Di Pietro, R ^a   Piantelli, M ^a   Consoli, A ^a,b  

^a UNIVERSITY OF CHIETI   (Italy)

^b Pescara Hospital   (Italy)

Author keywords

GDM; HUVEC; Nitrotyrosine; NO bioavailability; Oxidative stress

Indexed keywords

3 NITROTYROSINE; CYCLIC GMP; INTERCELLULAR ADHESION MOLECULE 1; MESSENGER RNA; NITRIC OXIDE SYNTHASE; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1; 3-NITROTYROSINE; CYCLIC AMP; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUCOSE BLOOD LEVEL; NITRIC OXIDE; TYROSINE;

ADULT; ARTICLE; ATHEROSCLEROSIS; BLOOD GLUCOSE MONITORING; CELL ADHESION ASSAY; CONTROLLED STUDY; DIMERIZATION; ENDOTHELIAL DYSFUNCTION; ENZYME IMMUNOASSAY; FEMALE; FLOW CYTOMETRY; HOMEOSTASIS; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPERGLYCEMIA; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LEUKOCYTE ADHERENCE; OXIDATIVE STRESS; PREGNANCY DIABETES MELLITUS; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RNA EXTRACTION; UMBILICAL VEIN; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; BLOOD; CELL ADHESION; COMPLICATION; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE TEST; LEUKOCYTE; METABOLISM; PATHOLOGY; PREGNANCY; UMBILICAL CORD; UMBILICAL VEIN ENDOTHELIAL CELL; VASCULAR DISEASE;

ADULT; ATHEROSCLEROSIS; BLOOD GLUCOSE; CELL ADHESION; CYCLIC AMP; DIABETES, GESTATIONAL; FEMALE; GLUCOSE TOLERANCE TEST; HOMEOSTASIS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; HYPERGLYCEMIA; LEUKOCYTES; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; OXIDATIVE STRESS; PREGNANCY; TYROSINE; UMBILICAL CORD; VASCULAR DISEASES;

EID: 84920052706     PISSN: 09394753     EISSN: 15903729     Source Type: Journal    
DOI: 10.1016/j.numecd.2014.06.005     Document Type: Article

References (30)

1. Shah B.R., Retnakaran R., Booth G.L. Increased risk of cardiovascular disease in young women following gestational diabetes mellitus. Diabetes Care 2008 Aug, 31(8):1668-1669.
2. Wolf M., Sauk J., Shah A., Vossen Smirnakis K., Jimenez-Kimble R., Ecker J.L., et al. Inflammation and glucose intolerance: a prospective study of gestational diabetes mellitus. Diabetes Care 2004 Jan, 27(1):21-27.
3. Rogers L.K., Velten M. Maternal inflammation, growth retardation, and preterm birth: insights into adult cardiovascular disease. Life Sci 2011 Sep 26, 89(13-14):417-421.
4. Yessoufou A., Moutairou K. Maternal diabetes in pregnancy: early and long-term outcomes on the offspring and the concept of "metabolic memory". Exp Diabetes Res 2011, 2011:218598.
5. Ozuguz U., Isik S., Berker D., Arduc A., Tutuncu Y., Akbaba G., et al. Gestational diabetes and subclinical inflammation: evaluation of first year postpartum outcomes. Diabetes Res Clin Pract 2011 Dec, 94(3):426-433.
6. Franzini L., Ardigo D., Valtuena S., Pellegrini N., Del Rio D., Bianchi M.A., et al. Food selection based on high total antioxidant capacity improves endothelial function in a low cardiovascular risk population. Nutr Metab Cardiovasc Dis 2012 Jan, 22(1):50-57.
7. Picconi F., Di Flaviani A., Malandrucco I., Giordani I., Frontoni S. Impact of glycemic variability on cardiovascular outcomes beyond glycated hemoglobin. Evidence and clinical perspectives. Nutr Metab Cardiovasc Dis 2012 Sep, 22(9):691-696.
8. Cosentino F., Hishikawa K., Katusic Z.S., Luscher T.F. High glucose increases nitric oxide synthase expression and superoxide anion generation in human aortic endothelial cells. Circulation 1997 Jul 1, 96(1):25-28.
9. Sobrevia L., Yudilevich D.L., Mann G.E. Elevated D-glucose induces insulin insensitivity in human umbilical endothelial cells isolated from gestational diabetic pregnancies. J Physiol 1998 Jan 1, 506(Pt 1):219-230.
10. Ceriello A. New insights on oxidative stress and diabetic complications may lead to a "causal" antioxidant therapy. Diabetes Care 2003 May, 26(5):1589-1596.
11. Tsuneki H., Sekizaki N., Suzuki T., Kobayashi S., Wada T., Okamoto T., et al. Coenzyme Q10 prevents high glucose-induced oxidative stress in human umbilical vein endothelial cells. Eur J Pharmacol 2007 Jul 2, 566(1-3):1-10.
12. Giri H., Chandel S., Dwarakanath L.S., Sreekumar S., Dixit M. Increased endothelial inflammation, sTie-2 and arginase activity in umbilical cords obtained from gestational diabetic mothers. PLoS One 2013, 8(12). e84546.
13. Tanaka J., Qiang L., Banks A.S., Welch C.L., Matsumoto M., Kitamura T., et al. Foxo1 links hyperglycemia to LDL oxidation and endothelial nitric oxide synthase dysfunction in vascular endothelial cells. Diabetes 2009 Oct, 58(10):2344-2354.
14. Qiang L., Tsuchiya K., Kim-Muller J.Y., Lin H.V., Welch C., Accili D. Increased atherosclerosis and endothelial dysfunction in mice bearing constitutively deacetylated alleles of foxo1 gene. J Biol Chem 2012 Apr 20, 287(17):13944-13951.
15. Volpe L., Cuccuru I., Lencioni C., Napoli V., Ghio A., Fotino C., et al. Early subclinical atherosclerosis in women with previous gestational diabetes mellitus. Diabetes Care 2008 May, 31(5):e32.
16. Takahashi M., Ikeda U., Masuyama J., Funayama H., Kano S., Shimada K. Nitric oxide attenuates adhesion molecule expression in human endothelial cells. Cytokine 1996 Nov, 8(11):817-821.
17. Ding H., Aljofan M., Triggle C.R. Oxidative stress and increased eNOS and NADPH oxidase expression in mouse microvessel endothelial cells. J Cell Physiol 2007 Sep, 212(3):682-689.
18. Cosentino F., Eto M., De Paolis P., van der Loo B., Bachschmid M., Ullrich V., et al. High glucose causes upregulation of cyclooxygenase-2 and alters prostanoid profile in human endothelial cells: role of protein kinase C and reactive oxygen species. Circulation 2003 Feb 25, 107(7):1017-1023.
19. Kojda G., Harrison D. Interactions between NO and reactive oxygen species: pathophysiological importance in atherosclerosis, hypertension, diabetes and heart failure. Cardiovasc Res 1999 Aug 15, 43(3):562-571.
20. Wang X.L., Rainwater D.L., Leone A., Mahaney M.C. Effects of diabetes on plasma nitrotyrosine levels. Diabet Med 2004 Jun, 21(6):577-580.
21. Gelisgen R., Genc H., Kayali R., Oncul M., Benian A., Guralp O., et al. Protein oxidation markers in women with and without gestational diabetes mellitus: a possible relation with paraoxonase activity. Diabetes Res Clin Pract 2011 Dec, 94(3):404-409.
22. Ceriello A., Novials A., Ortega E., Pujadas G., La Sala L., Testa R., et al. Hyperglycemia following recovery from hypoglycemia worsens endothelial damage and thrombosis activation in type 1 diabetes and in healthy controls. Nutr Metab Cardiovasc Dis 2014 Feb, 24(2):116-123.
23. Sobrevia L., Mann G.E. Dysfunction of the endothelial nitric oxide signalling pathway in diabetes and hyperglycaemia. Exp Physiol 1997 May, 82(3):423-452.
24. Johansen J.S., Harris A.K., Rychly D.J., Ergul A. Oxidative stress and the use of antioxidants in diabetes: linking basic science to clinical practice. Cardiovasc Diabetol 2005, 4(1):5.
25. Holman R.R., Paul S.K., Bethel M.A., Matthews D.R., Neil H.A. 10-year follow-up of intensive glucose control in type 2 diabetes. N Engl J Med 2008 Oct 9, 359(15):1577-1589.
26. Simeoni U., Barker D.J. Offspring of diabetic pregnancy: long-term outcomes. Semin Fetal Neonatal Med 2009 Apr, 14(2):119-124.
27. Gluckman P.D., Hanson M.A., Buklijas T., Low F.M., Beedle A.S. Epigenetic mechanisms that underpin metabolic and cardiovascular diseases. Nat Rev Endocrinol 2009 Jul, 5(7):401-408.
28. El-Osta A., Brasacchio D., Yao D., Pocai A., Jones P.L., Roeder R.G., et al. Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia. J Exp Med 2008 Sep 29, 205(10):2409-2417.
29. Ohtani K., Vlachojannis G.J., Koyanagi M., Boeckel J.N., Urbich C., Farcas R., et al. Epigenetic regulation of endothelial lineage committed genes in pro-angiogenic hematopoietic and endothelial progenitor cells. Circ Res 2011 Nov 11, 109(11):1219-1229.
30. De Marco A., Formoso G., Di Pietro N., Pandolfi A., De Laurenzi V., Federici M., et al. High Glucose effects on eNOS and SIRT1 expression and chromatin acetylation in endothelial cells. Diabetologia 2012, 55(S1):S506. [Meeting Abstract].