Heavy metal transport and detoxification by crustacean epithelial lysosomes

Epithelial Transport Physiology

Volumn , Issue , 2010, Pages 49-71

  Ahearn, Gregory A ^a   Sterling, Kenneth M ^a   Mandal, Prabir K ^a   Roggenbeck, Barbara ^a  

^a UNIVERSITY OF NORTH FLORIDA   (United States)

Author keywords

Concretion formation; Detoxification; Heavy metal transport; Hepatopancreas; Homarus americanus; Lysosomes; OAT1; Organic anion exchanger; Sequestration; Zinc

Indexed keywords

EID: 84919953763     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-1-60327-229-2_3     Document Type: Chapter

References (47)

1. Ahearn HRH, Ahearn GA, Gomme J. Effects of cadmium on integumentary uptake of 3H-Lhistidine in the marine polychaete worm, Nereis succinea. J. Exp. Biol. 2000; 203: 2877-2885.
2. Peppler JE, Ahearn GA. Effect of heavy metals on the uptake of 3H-L-histidine by the polychaete Nereis succinea. Comp. Biochem. Physiol. Part C 2003; 136(2):181-189.
3. Verbost PM, Van Rooij J, Flik G, Lock RAC, Bonga SEW. The movement of cadmium through freshwater trout branchial epithelium and its interference with calcium transport. J. Exp. Biol. 1989; 145: 185-197.
4. Bury NR, Grosell M, Grover AK, Wood CM. ATP-dependent silver transport across the basolateral membrane of rainbow trout gills. Toxicol. Appl. Pharmacol. 1999; 159: 1-8.
5. Bury NR, Walker PA, Glover CN. Nutritive metal uptake in teleost fish. J. Exp. Biol. 2003; 206: 11-23.
6. Grosell M, Wood CM. Copper uptake across rainbow trout gills: mechanisms of apical entry. J. Exp. Biol. 2002; 205: 1179-1188.
7. 2+are co-transported by a dipeptide transport system in lobster (Homarus americanus) intestine. J. Exp. Biol. 2005; 208: 287-296.
8. Conrad EM, Ahearn GA. Transepithelial transport of zinc and L-histidine across perfused intestine of American lobster, Homarus americanus. J. Comp. Physiol. B. 2007; 177: 297-307.
9. Viarengo A. Heavy metals in marine invertebrates: Mechanisms of regulation and toxicity at the cellular level. Rev. Aquatic Sci. 1989; 1: 295-317.
10. KleinMJ, Ahearn GA. Calcium transport processes of lobster hepatopancreatic mitochondria. J. Exp. Zool. 1999; 283: 147-159.
11. Chavez-Crooker P, Garrido N, Ahearn GA. Copper transport by lobster hepatopancreatic epithelial cells separated by centrifugal elutriation: measurements with the fluorescent dye, Phen Green. J. Exp. Biol. 2001; 204: 1433-1444.
12. Chavez-Crooker P, Garrido N, Pozo P, Ahearn GA. Copper transport by lobster (Homarus americanus) hepatopancreatic lysosomes. Comp. Biochem. Physiol. Part C. 2003; 135(2): 107-118.
13. 2+ transport by lobster hepatopancreatic lysosomal membrane vesicles. J. Exp. Zool. 2006; 305A: 203-214.
14. 2+transport by lobster hepatopancreatic endoplasmic reticulum. J. Exp. Zool. 2005; 303A: 515-526.
15. Brown BE. The form and function of metal-containing "granules" in invertebrate tissues. Biol. Rev. 1982; 57: 621-667.
16. Mason AZ, Simkiss K. Sites of mineral deposition in metal-accumulating cells. Exp. Cell Res. 1982; 139:383-391.
17. Al-Mohanna SY, Nott JA. The accumulation of metals in the hepatopancreas of the shrimp, Penaeus semisulcatus de Haan (Crustacea: Decapoda) during the moult cycle. Proc. Confr. Mar. Environ. Pollution, 1985; pp. 195-209.
18. Coombs T, George SG. Mechanisms of immobilization and detoxification of metals in marine organisms. In: Physiology and behaviour of marine organisms (McLusky, D. S. and Berry, A. J., eds.), 1978; pp. 179-187, Pergamon Press, New York.
19. George SG, Pirie BJS, Cheyne AR, Coombs TL, Grant PT. Detoxification of metals by marine bivalves: An ultrastructural study on the compartmentation of copper and zinc in the oyster Ostrea edulis. Mar. Biol. 1978; 45: 147-156.
20. Mauri M, Orlando E. Experimental study on renal concretions in the wedge shell Donax trunculus L. J. Exp. Mar. Biol. UK. 1982; 63: 47-57.
21. Mason AZ, Simkiss K, Ryan KP. The ultrastructural localization of metals in specimens of Littorina littorea collected from clean and polluted sites. J. Exp. Mar. Biol. UK. 1984; 64: 699-720.
22. Hopkin SP. Ecophysiology of metals in terrestrial invertebrates. 1989; London, Elsevier Applied Science.
23. Pisoni RL, Thoene JG. The transport systems of mammalian lysosomes. Biochim. Biophys. Acta 1991; 1071: 351-373.
24. Chou HF, Vadgama J, Jonas AJ. Lysosomal transport of small molecules. Biochem. Med. Metab. Biol. 1992; 48: 179-193.
25. Suzuki M, Gitlin JD. Intracellular localization of the Menkes and Wilson's disease proteins and their role in intracellular copper transport. Pediatrics Int. 1999; 41: 436-442.
26. Rees EM, Lee J, Thiele DJ. Mobilization of intracellular copper stores by the Ctr2 vacuolar copper transporter. J. Biol. Chem. 2004; 279(52) 54221-54229.
27. Palmiter RD, Cole TB, Findley SD. ZnT-2, a mammalian protein that confers resistance to zinc by facilitating vesicular sequestration. EMBO J. 1996a; 15:1784-1791.
28. Palmiter RD, Cole TB, Findley SD. ZnT-3, a putative transporter of zinc into synaptic vesicles. Proc. Natl. Acad. Sci. USA 1996b; 93: 14934-14939.
29. Gaither LA, Eide DJ. Eukaryotic zinc transporters and their regulation. Biometals. 2001; 14: 251-270.
30. Liuzzi JP, Cousins RJ. Mammalian zinc transporters. Ann. Rev. Nutr. 2004; 24: 151-172.
31. Wang A, Cortax N, Edelman IS. Mg-dependent, Zn-ATPase: Enzymatic characteristics, ion specificities, and tissue distribution. J. Membr. Biol. 2001; 181: 11-20.
32. Hussain D, Haydon MJ, Wang Y, Wong E, Sherson SM, Young J, Camakaris J, Harper JF, Cobbett CS. P-type ATPase heavy metal transporters with roles in essential zinc homeostasis in Arabidopsis. The Plant Cell. 2004; 16: 1327-1339.
33. MacDiarmid CW, Milanick MA, Eide DJ. Biochemical properties of vacuolar zinc transport systems of Saccharomyces cerevisiae. J. Biol. Chem. 2002; 277: 39187-39194.
34. Havelaar AC, de Gast IL, Snijders S, Beerens CEMT, Mancini GMS, Verheijen FW. Characterization of a heavy metal ion transporter in the lysosomal membrane. FEBS Lett. 1998; 436: 223-227.
35. Truong-Tran AQ, Ruffin RE, Zalewski PD. Visualization of labile zinc in apoptosis of primary airway epithelial cells and cell lines. Am. J. Phyisol. Lung Cell Mol. Physiol. 2000; 279: L1172-L1183.
36. Truong-Tran AQ, Carter J, Ruffin R, Zalewski PD. New insights into the role of zinc in the respiratory epithelium. Immun. Cell Biol. 2001; 70: 170-177.
37. Beyersmann D, Haase H. Functions of zinc in signaling, proliferation and differentiation of mammalian cells. Biometals. 2001; 14: 331-341.
38. Maret W. Cellular zinc and redox states converge in the metallothionein/thionein pair. J. Nutr. 2003; 133: 1460S-1462S.
39. Chavez-Crooker P, Garrido N, Ahearn GA. Copper transport by lobster (Homarus americanus) hepatopancreatic mitochondria. J. Exp. Biol. 2002; 205: 405-413.
40. Hopfer U, Nelson K, Perrotto J, Isselbacher KJ. Glucose transport in isolated brush border membrane from rat small intestine. J. Biol. Chem. 1973; 248: 25-32.
41. + buffers. Methods Cell Biol. 1994; 40: 3-29.
42. Sterling KM, Mandal, PK, Roggenbeck, BA, Ahearn, GA, Gerencser, GA, and Ahearn, GA. Heavy metal detoxification in crustacean epithelial lysosomes: role of anions in the compartmentalization process. J. Exp. Biol. 2007; 210: 3484-3493.
43. Ahearn GA, Mandal PK, Mandal A. Mechanisms of heavy metal sequestration and detoxification in crustaceans: A review. J. Comp. Physiol. B 2004; 174: 439-452.
44. Brouwer M, Schlenk D, Ringwood AH, Brouwer-Hoexum T. Metal-specific induction of metallothionein isoforms in the blue crab Callinectes sapidus in response to single- And mixed-metal exposure. Arch. Biochem. Physiol. 1992; 294(2): 461-468.
45. Syring RA, Brouwer-Hoexum T, Brouwer M. Cloning and sequencing of cDNAs encoding for a novel copper-specific metallothionein and two cadmium-inducible metallothioneins from the blue crab Callinectes sapidus. Comp. Biochem. Physiol. C Toxicol. Pharmacol. 2000; 125: 325-332.
46. Zalups, R, Barfuss, DW. Renal organic anion transport system: A mechanism for the basolateral uptake of mercury-thiol conjugates along the pars recta of the proximal tubule. Toxicol. Appl. Pharmacol. 2002; 182: 234-243.
47. Thamotharan M, Lombardo YB, Bawani SZ, Adibi SA. An active mechanism for completion of the final stage of protein degradation in the liver, lysosomal transport of dipeptides. J. Biol. Chem. 1997; 272:11786-11790.