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Volumn 3, Issue 4, 2014, Pages 229-236

Neuromodulation therapies in the elderly depressed patient

Author keywords

Brain stimulation; DBS; Depression; ECT; Elderly; Late life depression; Major depression; MDD; Mood disorders; MST; Neuromodulation; Resistant depression; rTMS; tDCS; TRD; Treatment; VNS

Indexed keywords

4 AMINOBUTYRIC ACID;

EID: 84919952263     PISSN: None     EISSN: 21967865     Source Type: Journal    
DOI: 10.1007/s13670-014-0098-1     Document Type: Article
Times cited : (3)

References (73)
  • 2
    • 2942601324 scopus 로고    scopus 로고
    • Major depression in community-dwelling middle-aged and older adults: Prevalence and 2- and 4-year follow-up symptoms
    • 15099417 10.1017/S0033291703001764
    • Mojtabai R, Olfson M. Major depression in community-dwelling middle-aged and older adults: prevalence and 2- and 4-year follow-up symptoms. Psychol Med. 2004;34:623-34.
    • (2004) Psychol Med , vol.34 , pp. 623-634
    • Mojtabai, R.1    Olfson, M.2
  • 7
    • 0000556957 scopus 로고    scopus 로고
    • The natural history of depression and the anxiety disorders in older people: The Islington community study
    • 1:STN:280:DyaK1c7jvFegsw%3D%3D 9547122
    • Livingston G, Watkin V, Milne B, Manela MV, Katona C. The natural history of depression and the anxiety disorders in older people: the Islington community study. J Affect Disord. 1997;46:255-62.
    • (1997) J Affect Disord , vol.46 , pp. 255-262
    • Livingston, G.1    Watkin, V.2    Milne, B.3    Manela, M.V.4    Katona, C.5
  • 8
    • 84865677126 scopus 로고    scopus 로고
    • Older adults with severe, treatment-resistant depression
    • 1:CAS:528:DC%2BC38XhsFalsLfL
    • Unutzer J, Park M. Older adults with severe, treatment-resistant depression. JAMA J Am Med Assoc. 2012;308:909-18.
    • (2012) JAMA J Am Med Assoc , vol.308 , pp. 909-918
    • Unutzer, J.1    Park, M.2
  • 9
    • 0025078699 scopus 로고
    • The practice of ECT: Recommendations for treatment, training and privileging
    • American Psychiatric Association. Task Force on Electroconvulsive T
    • American Psychiatric Association. Task Force on Electroconvulsive T. The practice of ECT: recommendations for treatment, training and privileging. Convuls Ther. 1990;6:85-120.
    • (1990) Convuls Ther , vol.6 , pp. 85-120
  • 10
    • 69649083323 scopus 로고    scopus 로고
    • Canadian Network for Mood and Anxiety Treatments (CANMAT) Clinical guidelines for the management of major depressive disorder in adults. IV. Neurostimulation therapies
    • Canadian Network for M, Anxiety T 19656575 10.1016/j.jad.2009.06.039
    • Kennedy SH, Milev R, Giacobbe P, Ramasubbu R, Lam RW, Parikh SV, Patten SB, Ravindran AV, Canadian Network for M, Anxiety T. Canadian Network for Mood and Anxiety Treatments (CANMAT) Clinical guidelines for the management of major depressive disorder in adults. IV. Neurostimulation therapies. J Affect Disord. 2009;117 Suppl 1:S44-53.
    • (2009) J Affect Disord , vol.117 , pp. 44-S53
    • Kennedy, S.H.1    Milev, R.2    Giacobbe, P.3    Ramasubbu, R.4    Lam, R.W.5    Parikh, S.V.6    Patten, S.B.7    Ravindran, A.V.8
  • 11
    • 84887606345 scopus 로고    scopus 로고
    • The role of electroconvulsive and neuromodulation therapies in the treatment of geriatric depression
    • This is succient review of geraitric depression and shows evidence of safety and efficacy of ECT and gives a breif overwiew of other the neuromodulation therapies in geriatric depression
    • Riva-Posse P, Hermida AP, McDonald WM. The role of electroconvulsive and neuromodulation therapies in the treatment of geriatric depression. Psychiatr Clin N Am. 2013;36:607-30. This is succient review of geraitric depression and shows evidence of safety and efficacy of ECT and gives a breif overwiew of other the neuromodulation therapies in geriatric depression.
    • (2013) Psychiatr Clin N Am , vol.36 , pp. 607-630
    • Riva-Posse, P.1    Hermida, A.P.2    McDonald, W.M.3
  • 12
    • 0041383996 scopus 로고    scopus 로고
    • A meta-analysis of electroconvulsive therapy efficacy in depression
    • 12972983 10.1097/00124509-200309000-00005
    • Kho KH, van Vreeswijk MF, Simpson S, Zwinderman AH. A meta-analysis of electroconvulsive therapy efficacy in depression. J ECT. 2003;19:139-47.
    • (2003) J ECT , vol.19 , pp. 139-147
    • Kho, K.H.1    Van Vreeswijk, M.F.2    Simpson, S.3    Zwinderman, A.H.4
  • 13
    • 33645827571 scopus 로고    scopus 로고
    • The diagnosis and treatment of depression in Parkinson's disease
    • 16569383 10.1007/s11940-006-0015-9
    • McDonald WM, Holtzheimer 3rd PE, Byrd EH. The diagnosis and treatment of depression in Parkinson's disease. Curr Treat Options Neurol. 2006;8:245-55.
    • (2006) Curr Treat Options Neurol , vol.8 , pp. 245-255
    • McDonald, W.M.1    Holtzheimer, P.E.2    Byrd, E.H.3
  • 15
    • 84857921759 scopus 로고    scopus 로고
    • Is electroconvulsive therapy (ECT) effective and safe for treatment of depression in dementia? A short review
    • 22330702 10.1097/YCT.0b013e31823a0f5a
    • Oudman E. Is electroconvulsive therapy (ECT) effective and safe for treatment of depression in dementia? A short review. J ECT. 2012;28:34-8.
    • (2012) J ECT , vol.28 , pp. 34-38
    • Oudman, E.1
  • 16
    • 84155178085 scopus 로고    scopus 로고
    • Safety and efficacy of electroconvulsive therapy for the treatment of agitation and aggression in patients with dementia
    • Dementia and depression are common and coexist and retroespective chart reveiws of 16 patients shows that ECT is effective in decreasing agitation and aggression. This article also gives insight into modification and management of side effects that happened during the ECT. This article may increase the comfort level of psychiatrists in using ECT in this population
    • Ujkaj M, Davidoff DA, Seiner SJ, Ellison JM, Harper DG, Forester BP. Safety and efficacy of electroconvulsive therapy for the treatment of agitation and aggression in patients with dementia. Am J Geriatr Psychiatr Off J Am Assoc Geriatr Psychiatr. 2012;20:61-72. Dementia and depression are common and coexist and retroespective chart reveiws of 16 patients shows that ECT is effective in decreasing agitation and aggression. This article also gives insight into modification and management of side effects that happened during the ECT. This article may increase the comfort level of psychiatrists in using ECT in this population.
    • (2012) Am J Geriatr Psychiatr off J Am Assoc Geriatr Psychiatr , vol.20 , pp. 61-72
    • Ujkaj, M.1    Davidoff, D.A.2    Seiner, S.J.3    Ellison, J.M.4    Harper, D.G.5    Forester, B.P.6
  • 17
    • 84855358256 scopus 로고    scopus 로고
    • Successful use of ECT in post stroke depression
    • Harmandayan M, et al. Successful use of ECT in post stroke depression. Gen Hosp Psychiatry. 2012;34:102.e5-6.
    • (2012) Gen Hosp Psychiatry , vol.34 , pp. 102e5-102e6
    • Harmandayan, M.1
  • 18
    • 0035206160 scopus 로고    scopus 로고
    • The use of electroconvulsive therapy in special patient populations
    • 1:STN:280:DC%2BD3Mnjslaitw%3D%3D 11692973
    • Rabheru K. The use of electroconvulsive therapy in special patient populations. Can J Psychiatry. 2001;46(8):710-9.
    • (2001) Can J Psychiatry , vol.46 , Issue.8 , pp. 710-719
    • Rabheru, K.1
  • 19
  • 21
    • 84857912247 scopus 로고    scopus 로고
    • Maintenance electroconvulsive therapy (M-ECT) after acute response: Examining the evidence for who, what, when, and how?
    • 22330700 10.1097/YCT.0b013e3182455758
    • Rabheru K. Maintenance electroconvulsive therapy (M-ECT) after acute response: examining the evidence for who, what, when, and how? J ECT. 2012;28:39-47.
    • (2012) J ECT , vol.28 , pp. 39-47
    • Rabheru, K.1
  • 23
    • 84880136961 scopus 로고    scopus 로고
    • Continuation electroconvulsive therapy with pharmacotherapy versus pharmacotherapy alone for prevention of relapse of depression: A randomized controlled trial
    • 23303421 10.1097/YCT.0b013e318276591f Rare to find randomized controlled studies in ECT that gave gudielines on maintenace ECT.A good study that can be used by psychiatrist as evidence based treatment option
    • Nordenskjold A, von Knorring L, Ljung T, Carlborg A, Brus O, Engstrom I. Continuation electroconvulsive therapy with pharmacotherapy versus pharmacotherapy alone for prevention of relapse of depression: a randomized controlled trial. J ECT. 2013;29:86-92. Rare to find randomized controlled studies in ECT that gave gudielines on maintenace ECT.A good study that can be used by psychiatrist as evidence based treatment option.
    • (2013) J ECT , vol.29 , pp. 86-92
    • Nordenskjold, A.1    Von Knorring, L.2    Ljung, T.3    Carlborg, A.4    Brus, O.5    Engstrom, I.6
  • 26
    • 74249121646 scopus 로고    scopus 로고
    • Seizure threshold in a large sample: Implications for stimulus dosing strategies in bilateral electroconvulsive therapy: A report from CORE
    • 2792571 19972637 10.1097/YCT.0b013e31819c76ff
    • Petrides G, Braga RJ, Fink M, Mueller M, Knapp R, Husain M, Rummans T, Bailine S, Malur C, O'Connor K, Kellner C, Group C. Seizure threshold in a large sample: implications for stimulus dosing strategies in bilateral electroconvulsive therapy: a report from CORE. J ECT. 2009;25:232-7.
    • (2009) J ECT , vol.25 , pp. 232-237
    • Petrides, G.1    Braga, R.J.2    Fink, M.3    Mueller, M.4    Knapp, R.5    Husain, M.6    Rummans, T.7    Bailine, S.8    Malur, C.9    O'Connor, K.10    Kellner, C.11    Group, C.12
  • 27
    • 0037364165 scopus 로고    scopus 로고
    • Increased cortical GABA concentration in depressed patients receiving ECT
    • 12611844 10.1176/appi.ajp.160.3.577
    • Sanacora G, Mason GF, Rothman DL, et al. Increased cortical GABA concentration in depressed patients receiving ECT. Am J Psychiatry. 2003;160(3):577-9.
    • (2003) Am J Psychiatry , vol.160 , Issue.3 , pp. 577-579
    • Sanacora, G.1    Mason, G.F.2    Rothman, D.L.3
  • 29
    • 84898439246 scopus 로고    scopus 로고
    • Electroconvulsive therapy mediates neuroplasticity of white matter microstructure in major depression
    • Lyden H, Espinoza RT, Pirnia T, Clark K, Joshi SH, Leaver AM, et al. Electroconvulsive therapy mediates neuroplasticity of white matter microstructure in major depression. Transl Psychiatry. 2014;1-8. An interesting original article that shows the possibility that ECT can modify microstructre in white matter of the brain. This opens up the possiblity of understanding ECTand its effectiveness clinically.
    • (2014) Transl Psychiatry , pp. 1-8
    • Lyden, H.1    Espinoza, R.T.2    Pirnia, T.3    Clark, K.4    Joshi, S.H.5    Leaver, A.M.6
  • 35
    • 47949128934 scopus 로고    scopus 로고
    • Safety and efficacy of Vagus Nerve Stimulation in treatment-resistant depression. A systematic review
    • 18374988
    • Daban C, Martinez-Aran A, Cruz N, Vieta E. Safety and efficacy of Vagus Nerve Stimulation in treatment-resistant depression. A systematic review. J Affect Disord. 2008;110:1-15.
    • (2008) J Affect Disord , vol.110 , pp. 1-15
    • Daban, C.1    Martinez-Aran, A.2    Cruz, N.3    Vieta, E.4
  • 38
    • 0034765204 scopus 로고    scopus 로고
    • Memory alterations during acute high-intensity vagus nerve stimulation
    • 1:STN:280:DC%2BD3MrmslSquw%3D%3D 11673019
    • Helmstaedter C, Hoppe C, Elger CE. Memory alterations during acute high-intensity vagus nerve stimulation. Epilepsy Res. 2001;47:37-42.
    • (2001) Epilepsy Res , vol.47 , pp. 37-42
    • Helmstaedter, C.1    Hoppe, C.2    Elger, C.E.3
  • 39
    • 0034926868 scopus 로고    scopus 로고
    • Therapeutic application of repetitive transcranial magnetic stimulation: A review
    • 1:STN:280:DC%2BD3MvgvVSiug%3D%3D
    • Wassermann EM, Lisanby SH. Therapeutic application of repetitive transcranial magnetic stimulation: a review. Clin Neurophysiol Off J Int Fed Clin Neurophysiol. 2001;112:1367-77.
    • (2001) Clin Neurophysiol off J Int Fed Clin Neurophysiol , vol.112 , pp. 1367-1377
    • Wassermann, E.M.1    Lisanby, S.H.2
  • 40
    • 84876802367 scopus 로고    scopus 로고
    • Applications of transcranial magnetic stimulation and magnetic seizure therapy in the study and treatment of disorders related to cerebral aging
    • 3622472 23576892 An excellent overview of rTMS and MST in geriatric population, a good reading with insights into its effect on cognition as well, even though rTMs is not used widely
    • Luber B, McClintock SM, Lisanby SH. Applications of transcranial magnetic stimulation and magnetic seizure therapy in the study and treatment of disorders related to cerebral aging. Dialogues Clin Neurosci. 2013;15:87-98. An excellent overview of rTMS and MST in geriatric population, a good reading with insights into its effect on cognition as well, even though rTMs is not used widely.
    • (2013) Dialogues Clin Neurosci , vol.15 , pp. 87-98
    • Luber, B.1    McClintock, S.M.2    Lisanby, S.H.3
  • 42
    • 78751645877 scopus 로고    scopus 로고
    • Neuropsychologic effects of neuromodulation techniques for treatment-resistant depression: A review
    • 3023999 21255751 10.1016/j.brs.2010.01.005
    • Moreines JL, McClintock SM, Holtzheimer PE. Neuropsychologic effects of neuromodulation techniques for treatment-resistant depression: a review. Brain Stimulation. 2011;4:17-27.
    • (2011) Brain Stimulation , vol.4 , pp. 17-27
    • Moreines, J.L.1    McClintock, S.M.2    Holtzheimer, P.E.3
  • 43
    • 57849166192 scopus 로고    scopus 로고
    • Daily left prefrontal repetitive transcranial magnetic stimulation in the acute treatment of major depression: Clinicla predictors of outcome in a multisite, randomized controlled clinical trial
    • 18704101 10.1038/npp.2008.118
    • Lisanby SH, Husain MM, Rosenquist PB, Maixner D, Gutierrez R, Krystal A, George MS. Daily left prefrontal repetitive transcranial magnetic stimulation in the acute treatment of major depression: clinicla predictors of outcome in a multisite, randomized controlled clinical trial. Neuropsychopharmacology. 2009;34:522-34.
    • (2009) Neuropsychopharmacology , vol.34 , pp. 522-534
    • Lisanby, S.H.1    Husain, M.M.2    Rosenquist, P.B.3    Maixner, D.4    Gutierrez, R.5    Krystal, A.6    George, M.S.7
  • 46
    • 0034905376 scopus 로고    scopus 로고
    • A controlled study of repetitive transcranial magnetic stimulation as a treatment of depression in the elderly
    • 1:STN:280:DC%2BD3MvkvF2ksg%3D%3D
    • Manes F, Jorge R, Morcuende M, Yamada T, Paradiso S, Robinson RG. A controlled study of repetitive transcranial magnetic stimulation as a treatment of depression in the elderly. Int Psychogeriatr IPA. 2001;13:225-31.
    • (2001) Int Psychogeriatr IPA , vol.13 , pp. 225-231
    • Manes, F.1    Jorge, R.2    Morcuende, M.3    Yamada, T.4    Paradiso, S.5    Robinson, R.G.6
  • 48
    • 84855247674 scopus 로고    scopus 로고
    • Treatment of late-life depression: A role of non-invasive brian stimualtion techniques
    • 3619934 22200133 10.3109/09540261.2011.633501 Another good review of all studies of rTMs and MST
    • Jorge RE, Robinson RG. Treatment of late-life depression: a role of non-invasive brian stimualtion techniques. Int Rev Psychiatry. 2011;23(5):437-44. Another good review of all studies of rTMs and MST.
    • (2011) Int Rev Psychiatry , vol.23 , Issue.5 , pp. 437-444
    • Jorge, R.E.1    Robinson, R.G.2
  • 49
    • 40349106140 scopus 로고    scopus 로고
    • Treatment of vascualr depression using repetitive transcranial magnetic stimulation
    • 18316673 10.1001/archgenpsychiatry.2007.45
    • Jorge RE, Moser DJ, Acion L, Robinson RG. Treatment of vascualr depression using repetitive transcranial magnetic stimulation. Arch Gen Psychiatry. 2008;65:268-76.
    • (2008) Arch Gen Psychiatry , vol.65 , pp. 268-276
    • Jorge, R.E.1    Moser, D.J.2    Acion, L.3    Robinson, R.G.4
  • 50
    • 0036459918 scopus 로고    scopus 로고
    • Update on magnetic seizure therapy: A novel form of convulsive therapy
    • 12468992 10.1097/00124509-200212000-00003
    • Lisanby SH. Update on magnetic seizure therapy: a novel form of convulsive therapy. J ECT. 2002;18:182-8.
    • (2002) J ECT , vol.18 , pp. 182-188
    • Lisanby, S.H.1
  • 51
    • 0642277739 scopus 로고    scopus 로고
    • Safety and feasibility of magnetic seizure therapy (MST) in major depression: Randomized within-subject comparison with electroconvulsive therapy
    • Lisanby SH, Luber B, Schlaepfer TE, Sackeim HA. Safety and feasibility of magnetic seizure therapy (MST) in major depression: randomized within-subject comparison with electroconvulsive therapy. Neuropsychopharmacol Off Publ Am Coll Neuropsychopharmacol. 2003;28:1852-65.
    • (2003) Neuropsychopharmacol off Publ Am Coll Neuropsychopharmacol , vol.28 , pp. 1852-1865
    • Lisanby, S.H.1    Luber, B.2    Schlaepfer, T.E.3    Sackeim, H.A.4
  • 54
    • 79955028962 scopus 로고    scopus 로고
    • Antidepressant effects, of magnetic seizure therapy and electroconvulsive therapy, in treatment-resistant depression
    • 20951997 10.1016/j.jpsychires.2010.09.008
    • Kayser S, Bewernick BH, Grubert C, Hadrysiewicz BL, Axmacher N, Schlaepfer TE. Antidepressant effects, of magnetic seizure therapy and electroconvulsive therapy, in treatment-resistant depression. J Psychiatr Res. 2011;45:569-76.
    • (2011) J Psychiatr Res , vol.45 , pp. 569-576
    • Kayser, S.1    Bewernick, B.H.2    Grubert, C.3    Hadrysiewicz, B.L.4    Axmacher, N.5    Schlaepfer, T.E.6
  • 55
    • 84856410874 scopus 로고    scopus 로고
    • Depression following traumatic brain injury: Epidemiology, risk factors and management
    • 1:CAS:528:DC%2BC38XnsF2qtLs%3D 22296315
    • Rapoport MJ. Depression following traumatic brain injury: epidemiology, risk factors and management. CNS Drugs. 2012;26:111-21.
    • (2012) CNS Drugs , vol.26 , pp. 111-121
    • Rapoport, M.J.1
  • 56
    • 24344485628 scopus 로고    scopus 로고
    • A patient with a resistant major depression disorder treated with deep brain stimulation in the inferior thalamic peduncle
    • 16145540 10.1227/01.NEU.0000170434.44335.19 discussion 585-593
    • Jimenez F, Velasco F, Salin-Pascual R, Hernandez JA, Velasco M, Criales JL, Nicolini H. A patient with a resistant major depression disorder treated with deep brain stimulation in the inferior thalamic peduncle. Neurosurgery. 2005;57:585-93. discussion 585-593.
    • (2005) Neurosurgery , vol.57 , pp. 585-593
    • Jimenez, F.1    Velasco, F.2    Salin-Pascual, R.3    Hernandez, J.A.4    Velasco, M.5    Criales, J.L.6    Nicolini, H.7
  • 57
    • 34247484059 scopus 로고    scopus 로고
    • Mood improvement after deep brain stimulation of the internal globus pallidus for tardive dyskinesia in a patient suffering from major depression
    • 16962613 10.1016/j.jpsychires.2006.07.010
    • Kosel M, Sturm V, Frick C, Lenartz D, Zeidler G, Brodesser D, Schlaepfer TE. Mood improvement after deep brain stimulation of the internal globus pallidus for tardive dyskinesia in a patient suffering from major depression. J Psychiatr Res. 2007;41:801-3.
    • (2007) J Psychiatr Res , vol.41 , pp. 801-803
    • Kosel, M.1    Sturm, V.2    Frick, C.3    Lenartz, D.4    Zeidler, G.5    Brodesser, D.6    Schlaepfer, T.E.7
  • 58
    • 49749152058 scopus 로고    scopus 로고
    • Subcallosal cingulate gyrus deep brain stimulation for treatment-resistant depression
    • 18639234 10.1016/j.biopsych.2008.05.034
    • Lozano AM, Mayberg HS, Giacobbe P, Hamani C, Craddock RC, Kennedy SH. Subcallosal cingulate gyrus deep brain stimulation for treatment-resistant depression. Biol Psychiatry. 2008;64:461-7.
    • (2008) Biol Psychiatry , vol.64 , pp. 461-467
    • Lozano, A.M.1    Mayberg, H.S.2    Giacobbe, P.3    Hamani, C.4    Craddock, R.C.5    Kennedy, S.H.6
  • 59
    • 84883247709 scopus 로고    scopus 로고
    • Double-blind optimization of subcallosal cingualte deep brain stimulation for treatment-resistant depression: A pilot study
    • 3756116 23527884 10.1503/jpn.120160 A small study but of improtance as research papers in DBS are difficult to conduct and getting a larger sample size is not prctical. Learning about stimulus parameters and adjusting the parameters throws some light on stimulus optimization for TRD
    • Ramasubbu R, Anderson S, Haffenden A, Chavda S, Kiss ZH. Double-blind optimization of subcallosal cingualte deep brain stimulation for treatment-resistant depression: a pilot study. J Psychiatry Neurosci. 2013;38(5):325-32. A small study but of improtance as research papers in DBS are difficult to conduct and getting a larger sample size is not prctical. Learning about stimulus parameters and adjusting the parameters throws some light on stimulus optimization for TRD.
    • (2013) J Psychiatry Neurosci , vol.38 , Issue.5 , pp. 325-332
    • Ramasubbu, R.1    Anderson, S.2    Haffenden, A.3    Chavda, S.4    Kiss, Z.H.5
  • 61
    • 43649091537 scopus 로고    scopus 로고
    • Neuropsychological impact of Cg25 deep brain stimulation for treatment-resistant depression: Preliminary results over 12 months
    • 18477883 10.1097/NMD.0b013e3181710927
    • McNeely HE, Mayberg HS, Lozano AM, Kennedy SH. Neuropsychological impact of Cg25 deep brain stimulation for treatment-resistant depression: preliminary results over 12 months. J Nerv Ment Dis. 2008;196:405-10.
    • (2008) J Nerv Ment Dis , vol.196 , pp. 405-410
    • McNeely, H.E.1    Mayberg, H.S.2    Lozano, A.M.3    Kennedy, S.H.4
  • 63
    • 84885129296 scopus 로고    scopus 로고
    • Deep brain stimulation for the treatment of Alzheimer disease and dementias
    • Interesting summary of three case studies that show some improvement in Alzheimer's and Parkinson's dementia. Preliminary and limited but innovative, even though not related to the present paper, depression and dementias in elderly can coexist, DBS should be explored as an option. Warrants further research
    • Laxton AW, Lozano AM. Deep brain stimulation for the treatment of Alzheimer disease and dementias. World Neurosurg. 2013;80:e21-8. Interesting summary of three case studies that show some improvement in Alzheimer's and Parkinson's dementia. Preliminary and limited but innovative, even though not related to the present paper, depression and dementias in elderly can coexist, DBS should be explored as an option. Warrants further research.
    • (2013) World Neurosurg , vol.80 , pp. 21-e28
    • Laxton, A.W.1    Lozano, A.M.2
  • 64
    • 68549125229 scopus 로고    scopus 로고
    • Treatment of depression with transcranial direct current stimulation (tDCS): A review
    • 19348793 10.1016/j.expneurol.2009.03.038
    • Nitsche MA, Boggio PS, Fregni F, Pascual-Leone A. Treatment of depression with transcranial direct current stimulation (tDCS): a review. Exp Neurol. 2009;219:14-9.
    • (2009) Exp Neurol , vol.219 , pp. 14-19
    • Nitsche, M.A.1    Boggio, P.S.2    Fregni, F.3    Pascual-Leone, A.4
  • 65
    • 77952416389 scopus 로고    scopus 로고
    • Direct current stimulation promotes BDNF-dependent synaptic plasticity: Potential implications for motor learning
    • 1:CAS:528:DC%2BC3cXmtVWlt7Y%3D 2864780 20434997
    • Fritsch B, Reis J, Martinowich K, Schambra HM, Ji Y, Cohen LG, Lu B. Direct current stimulation promotes BDNF-dependent synaptic plasticity: potential implications for motor learning. Neuron. 2010;66:198-204.
    • (2010) Neuron , vol.66 , pp. 198-204
    • Fritsch, B.1    Reis, J.2    Martinowich, K.3    Schambra, H.M.4    Ji, Y.5    Cohen, L.G.6    Lu, B.7
  • 66
    • 0034666046 scopus 로고    scopus 로고
    • Excitability changes induced in the human motor cortex by weak transcranial direct current stimulation
    • 1:CAS:528:DC%2BD3cXnt1anur4%3D 2270099 10990547
    • Nitsche MA, Paulus W. Excitability changes induced in the human motor cortex by weak transcranial direct current stimulation. J Physiol. 2000;527(Pt 3):633-9.
    • (2000) J Physiol , vol.527 , Issue.PART 3 , pp. 633-639
    • Nitsche, M.A.1    Paulus, W.2
  • 67
    • 79960623925 scopus 로고    scopus 로고
    • Effects of transcranial direct current stimulation (tDCS) on human regional cerebral blood flow
    • 3155947 21703350 10.1016/j.neuroimage.2011.06.018 Even thouhg this study was done in young healthy, it is intersting to learn that tDCS can increase cerebral blood flow in the brain region realted to the stimaulted area. Another postulate that has been entertained in the effect of brain stimulation therapies for depression
    • Zheng X, Alsop DC, Schlaug G. Effects of transcranial direct current stimulation (tDCS) on human regional cerebral blood flow. NeuroImage. 2011;58:26-33. Even thouhg this study was done in young healthy, it is intersting to learn that tDCS can increase cerebral blood flow in the brain region realted to the stimaulted area. Another postulate that has been entertained in the effect of brain stimulation therapies for depression.
    • (2011) NeuroImage , vol.58 , pp. 26-33
    • Zheng, X.1    Alsop, D.C.2    Schlaug, G.3
  • 70
    • 33845481658 scopus 로고    scopus 로고
    • Cognitive effects of repeated sessions of transcranial direct current stimulation in patients with depression
    • 16845648 10.1002/da.20201
    • Fregni F, Boggio PS, Nitsche MA, Rigonatti SP, Pascual-Leone A. Cognitive effects of repeated sessions of transcranial direct current stimulation in patients with depression. Depression Anxiety. 2006;23:482-4.
    • (2006) Depression Anxiety , vol.23 , pp. 482-484
    • Fregni, F.1    Boggio, P.S.2    Nitsche, M.A.3    Rigonatti, S.P.4    Pascual-Leone, A.5
  • 71
    • 84864282996 scopus 로고    scopus 로고
    • Transcranial direct current stimulation (tDCS) of the left dorsolateral prefrontal cortex modulates declarative memory
    • 21840287 10.1016/j.brs.2011.06.007 Even though this study is in young helathy college students, it can be of some merit to consider similar improvements in the depressed and the elderly
    • Javadi AH, Walsh V. Transcranial direct current stimulation (tDCS) of the left dorsolateral prefrontal cortex modulates declarative memory. Brain stimulation. 2012;5:231-41. Even though this study is in young helathy college students, it can be of some merit to consider similar improvements in the depressed and the elderly.
    • (2012) Brain Stimulation , vol.5 , pp. 231-241
    • Javadi, A.H.1    Walsh, V.2
  • 73
    • 84895734474 scopus 로고    scopus 로고
    • Repetitive transcranial magnetic stimulation versus electroconvulsive therapy for major depression: A systematic review and meta-analysis
    • 24556538 10.1016/j.pnpbp.2014.02.004 A well done meta-analysis that takes us back again to the most effective acute treatment for Major depression as ECT
    • Ren J, Li H, Palaniyappan L, Wang J, Rossini PM. Repetitive transcranial magnetic stimulation versus electroconvulsive therapy for major depression: a systematic review and meta-analysis. Prog Neuropsychopharmacol Biol Psychiatry. 2014;51:181-9. A well done meta-analysis that takes us back again to the most effective acute treatment for Major depression as ECT.
    • (2014) Prog Neuropsychopharmacol Biol Psychiatry , vol.51 , pp. 181-189
    • Ren, J.1    Li, H.2    Palaniyappan, L.3    Wang, J.4    Rossini, P.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.