GATA2 facilitates steroid receptor coactivator recruitment to the androgen receptor complex

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 51, 2014, Pages 18261-18266

  He, Bin ^a   Lanz, Rainer B ^a   Fiskus, Warren ^a   Geng, Chuandong ^a   Yi, Ping ^a   Hartig, Sean M ^a   Rajapakshe, Kimal ^a   Shou, John ^a   Wei, Liping ^a   Shah, Shrijal S ^a   Foley, Christopher ^a   Chew, Sue Anne ^a   Eedunuri, Vijay K ^b   Bedoya, Diego J ^a   Feng, Qin ^a   Minami, Takashi ^c   Mitsiades, Constantine S ^d   Frolov, Anna ^a   Weigel, Nancy L ^a   Hilsenbeck, Susan G ^a   Rosen, Daniel G ^a   Palzkill, Timothy ^a   Ittmann, Michael M ^a   Song, Yongcheng ^a   Coarfa, Cristian ^a   O'Malley, Bert W ^a   Mitsiades, Nicholas ^a   more..

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b ADRIENNE HELIS MALVIN MEDICAL RESEARCH FOUNDATION   (United States)

^c UNIVERSITY OF TOKYO   (Japan)

^d DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

AR signaling; GATA2; Prostate cancer; Small molecule inhibitor; Steroid receptor coactivator

Indexed keywords

ANDROGEN; ANDROGEN RECEPTOR; ANTINEOPLASTIC AGENT; BORTEZOMIB; HEPATOCYTE NUCLEAR FACTOR 3ALPHA; K7174; MESSENGER RNA; STEROID RECEPTOR COACTIVATOR 1; TRANSCRIPTION FACTOR GATA 2; UNCLASSIFIED DRUG; CHROMATIN; FOXA1 PROTEIN, HUMAN; GATA2 PROTEIN, HUMAN; NUCLEAR RECEPTOR COACTIVATOR;

22RV1 CELL; ANDROGEN DEPRIVATION THERAPY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER PROGNOSIS; CASTRATION RESISTANT PROSTATE CANCER; CELL PROLIFERATION; CHROMATIN; CONTROLLED STUDY; DRUG POTENCY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LNCAP CELL LINE; MALE; MOUSE; NEGATIVE FEEDBACK; NONHUMAN; NUCLEOTIDE SEQUENCE; PROSTATE CANCER; PROSTATE CANCER CELL LINE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; ENHANCER REGION; GENETIC TRANSCRIPTION; METABOLISM; PHYSIOLOGY; PROGNOSIS;

CELL PROLIFERATION; CHROMATIN; ENHANCER ELEMENTS, GENETIC; GATA2 TRANSCRIPTION FACTOR; HEPATOCYTE NUCLEAR FACTOR 3-ALPHA; HUMANS; MALE; NUCLEAR RECEPTOR COACTIVATORS; PROGNOSIS; RECEPTORS, ANDROGEN; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC;

EID: 84919935156     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1421415111     Document Type: Article

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