The coactivator PGC-1α regulates skeletal muscle oxidative metabolism independently of the nuclear receptor PPARβ/δ in sedentary mice fed a regular chow diet

Diabetologia

Volumn 57, Issue 11, 2014, Pages 2405-2412

  Pérez Schindler, Joaquín ^a,b   Svensson, Kristoffer ^a   Vargas Fernández, Elyzabeth ^a   Santos, Gesa ^a   Wahli, Walter ^c,d   Handschin, Christoph ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^c UNIVERSITY OF LAUSANNE   (Switzerland)

^d NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

Author keywords

Coregulators; Exercise; Nuclear receptors; Skeletal muscle metabolism

Indexed keywords

LACTIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PPARGC1A PROTEIN, MOUSE; TRANSCRIPTION FACTOR;

ADULT; AEROBIC METABOLISM; ANIMAL EXPERIMENT; ARTICLE; BLOOD ANALYSIS; BODY COMPOSITION; CALORIMETRY; CONTROLLED STUDY; EXERCISE; GENE EXPRESSION; GENE SILENCING; IN VIVO STUDY; INTRACELLULAR SIGNALING; LACTATE BLOOD LEVEL; MALE; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; OXYGEN CONSUMPTION; PHENOTYPE; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SKELETAL MUSCLE; ANIMAL; GENETICS; METABOLISM; PHYSIOLOGY; SEDENTARY LIFESTYLE; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CALORIMETRY, INDIRECT; MALE; MICE; MUSCLE, SKELETAL; PHYSICAL CONDITIONING, ANIMAL; PPAR DELTA; PPAR-BETA; SEDENTARY LIFESTYLE; TRANSCRIPTION FACTORS;

EID: 84919933338     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-014-3352-3     Document Type: Article

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