Investigations of the mechanism of the "proline effect" in tandem mass spectrometry experiments: The "pipecolic acid effect"

Journal of the American Society for Mass Spectrometry

Volumn 25, Issue 10, 2014, Pages 1705-1715

  Raulfs, Mary Disa M ^a   Breci, Linda ^b   Bernier, Matthew ^a,b,c   Hamdy, Omar M ^a,d   Janiga, Ashley ^a   Wysocki, Vicki ^b,c   Poutsma, John C ^a  

^a Dept of Economics and Thomas Jefferson Program in Public Policy at the College of William and Mary   (United States)

^b University of Arizona   (United States)

^c OHIO STATE UNIVERSITY   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Collision induced dissociation; Non protein amino acid; Peptide fragmentation; Proline effect

Indexed keywords

ALKALINITY; AMIDES; AMINO ACIDS; CONFORMATIONS; DISSOCIATION; MASS SPECTROMETRY; PEPTIDES; STEREOCHEMISTRY;

COLLISION-INDUCED DISSOCIATION; DIFFERENT MECHANISMS; FOUR-MEMBERED RINGS; FRAGMENTATION BEHAVIOR; INCREASED FLEXIBILITY; PEPTIDE FRAGMENTATION; PROLINE EFFECT; TANDEM MASS SPECTROMETRY;

ASCORBIC ACID;

AMIDE; HYDROGEN; NITROGEN; OXAZOLONE; PEPTIDE; PIPECOLIC ACID; PROLINE; ION; PEPTIDE FRAGMENT; PIPECOLIC ACID DERIVATIVE;

ARTICLE; CONTROLLED STUDY; DECOMPOSITION; DISSOCIATION; ELECTROSPRAY MASS SPECTROMETRY; HYDROGEN BOND; PROTEIN CONFORMATION; PROTON TRANSPORT; SOLID PHASE SYNTHESIS; TANDEM MASS SPECTROMETRY; CHEMISTRY; PROCEDURES;

IONS; PEPTIDE FRAGMENTS; PIPECOLIC ACIDS; PROLINE; TANDEM MASS SPECTROMETRY;

EID: 84919930558     PISSN: 10440305     EISSN: 18791123     Source Type: Journal    
DOI: 10.1007/s13361-014-0953-5     Document Type: Article

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