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Volumn 31, Issue 11, 2014, Pages 1-9

Minimal residual disease in acute lymphoblastic leukemia: optimal methods and clinical relevance, pitfalls and recent approaches

Author keywords

Acute lymphoblastic leukemia; Methods; Minimal residual disease

Indexed keywords

T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR RUNX1; GENETIC MARKER;

EID: 84919928629     PISSN: 13570560     EISSN: 1559131X     Source Type: Journal    
DOI: 10.1007/s12032-014-0266-3     Document Type: Review
Times cited : (13)

References (87)
  • 1
    • 0037082505 scopus 로고    scopus 로고
    • Precise quantification of minimal residual disease at day 29 allows identification of children with acute lymphoblastic leukemia and an excellent outcome
    • PID: 11830473, COI: 1:CAS:528:DC%2BD38XhtlWqsb0%3
    • Nyvold C, Madsen HO, Ryder LP, Seyfarth J, Svejgaard A, Clausen N, et al. Precise quantification of minimal residual disease at day 29 allows identification of children with acute lymphoblastic leukemia and an excellent outcome. Blood. 2002;99(4):1253–8.
    • (2002) Blood. , vol.99 , Issue.4 , pp. 1253-1258
    • Nyvold, C.1    Madsen, H.O.2    Ryder, L.P.3    Seyfarth, J.4    Svejgaard, A.5    Clausen, N.6
  • 2
    • 0038268132 scopus 로고    scopus 로고
    • Determination of minimal residual disease in leukaemia patients
    • PID: 1278679
    • Campana D. Determination of minimal residual disease in leukaemia patients. Br J Haematol. 2003;121(6):823–38.
    • (2003) Br J Haematol. , vol.121 , Issue.6 , pp. 823-838
    • Campana, D.1
  • 3
    • 33745212238 scopus 로고    scopus 로고
    • Flow-cytometric immunophenotyping of normal and malignant lymphocytes
    • PID: 1677662
    • Szczepański T, van der Velden VH, van Dongen JJ. Flow-cytometric immunophenotyping of normal and malignant lymphocytes. Clin Chem Lab Med. 2006;44(7):775–96.
    • (2006) Clin Chem Lab Med. , vol.44 , Issue.7 , pp. 775-796
    • Szczepański, T.1    van der Velden, V.H.2    van Dongen, J.J.3
  • 4
    • 15244340145 scopus 로고    scopus 로고
    • Molecular monitoring of childhood acute lymphoblastic leukemia using antigen receptor gene rearrangements and quantitative polymerase chain reaction technology
    • PID: 15749670, COI: 1:CAS:528:DC%2BD2MXjtFegu7g%3
    • Cazzaniga G, Biondi A. Molecular monitoring of childhood acute lymphoblastic leukemia using antigen receptor gene rearrangements and quantitative polymerase chain reaction technology. Haematologica. 2005;90(3):382–90.
    • (2005) Haematologica. , vol.90 , Issue.3 , pp. 382-390
    • Cazzaniga, G.1    Biondi, A.2
  • 6
    • 0037327771 scopus 로고    scopus 로고
    • Residual leukaemia after bone marrow transplant in children with acute lymphoblastic leukaemia after first haematological relapse or with poor initial presenting features
    • PID: 1258836
    • Bunin N, Johnston DA, Roberts WM, Ouspenskaia MV, Papusha VZ, Brandt MA, et al. Residual leukaemia after bone marrow transplant in children with acute lymphoblastic leukaemia after first haematological relapse or with poor initial presenting features. Br J Haematol. 2003;120(4):711–5.
    • (2003) Br J Haematol. , vol.120 , Issue.4 , pp. 711-715
    • Bunin, N.1    Johnston, D.A.2    Roberts, W.M.3    Ouspenskaia, M.V.4    Papusha, V.Z.5    Brandt, M.A.6
  • 7
    • 0346394011 scopus 로고    scopus 로고
    • Minimal residual disease as a surrogate marker for risk assignment to ALL patients
    • PID: 15024971, COI: 1:CAS:528:DC%2BD2cXotlOiug%3D%3
    • Cazzaniga G, Gaipa G, Rossi V, Biondi A. Minimal residual disease as a surrogate marker for risk assignment to ALL patients. Rev Clin Exp Hematol. 2003;7(3):292–323.
    • (2003) Rev Clin Exp Hematol. , vol.7 , Issue.3 , pp. 292-323
    • Cazzaniga, G.1    Gaipa, G.2    Rossi, V.3    Biondi, A.4
  • 8
    • 84979846414 scopus 로고    scopus 로고
    • Monitoring and managing minimal residual disease in acute lymphoblastic leukemia
    • Hoelzer D. Monitoring and managing minimal residual disease in acute lymphoblastic leukemia. Am Soc Clin Oncol Educ Book. 2013;33:290–3.
    • (2013) Am Soc Clin Oncol Educ Book. , vol.33 , pp. 290-293
    • Hoelzer, D.1
  • 9
    • 0034857383 scopus 로고    scopus 로고
    • Real-time quantitative PCR for detection of minimal residual disease before allogeneic stem cell transplantation predicts outcome in children with acute lymphoblastic leukemia
    • PID: 1151611
    • Van der Velden V, Joosten S, Willemse M, Van Wering E, Lankester A, Van Dongen J, et al. Real-time quantitative PCR for detection of minimal residual disease before allogeneic stem cell transplantation predicts outcome in children with acute lymphoblastic leukemia. Leukemia. 2001;15(9):1485.
    • (2001) Leukemia. , vol.15 , Issue.9 , pp. 1485
    • Van der Velden, V.1    Joosten, S.2    Willemse, M.3    Van Wering, E.4    Lankester, A.5    Van Dongen, J.6
  • 10
    • 0036736498 scopus 로고    scopus 로고
    • Minimal residual disease (MRD) status prior to allogeneic stem cell transplantation is a powerful predictor for post-transplant outcome in children with ALL
    • COI: 1:STN:280:DC%2BD38vkt1yjsg%3D%3
    • Bader P, Hancock J, Kreyenberg H, Goulde N, Niethammer D, Oakhill A, et al. Minimal residual disease (MRD) status prior to allogeneic stem cell transplantation is a powerful predictor for post-transplant outcome in children with ALL. Leukemia (08876924). 2002;16(9):1668–72.
    • (2002) Leukemia (08876924). , vol.16 , Issue.9 , pp. 1668-1672
    • Bader, P.1    Hancock, J.2    Kreyenberg, H.3    Goulde, N.4    Niethammer, D.5    Oakhill, A.6
  • 11
    • 77955714137 scopus 로고    scopus 로고
    • Preemptive alloimmune intervention in high-risk pediatric acute lymphoblastic leukemia patients guided by minimal residual disease level before stem cell transplantation
    • PID: 20535148, COI: 1:CAS:528:DC%2BC3cXhtVSmur%2F
    • Lankester AC, Bierings M, Van Wering E, Wijkhuijs A, de Weger R, Wijnen J, et al. Preemptive alloimmune intervention in high-risk pediatric acute lymphoblastic leukemia patients guided by minimal residual disease level before stem cell transplantation. Leukemia. 2010;24(8):1462–9.
    • (2010) Leukemia. , vol.24 , Issue.8 , pp. 1462-1469
    • Lankester, A.C.1    Bierings, M.2    Van Wering, E.3    Wijkhuijs, A.4    de Weger, R.5    Wijnen, J.6
  • 12
    • 84863999402 scopus 로고    scopus 로고
    • Minimal residual disease-guided treatment deintensification for children with acute lymphoblastic leukemia: results from the Malaysia–Singapore acute lymphoblastic leukemia 2003 study
    • PID: 22614971, COI: 1:CAS:528:DC%2BC38Xht1aisbn
    • Yeoh AEJ, Ariffin H, Chai ELL, Kwok CSN, Chan YH, Ponnudurai K, et al. Minimal residual disease-guided treatment deintensification for children with acute lymphoblastic leukemia: results from the Malaysia–Singapore acute lymphoblastic leukemia 2003 study. J Clin Oncol. 2012;30(19):2384–92.
    • (2012) J Clin Oncol. , vol.30 , Issue.19 , pp. 2384-2392
    • Yeoh, A.E.J.1    Ariffin, H.2    Chai, E.L.L.3    Kwok, C.S.N.4    Chan, Y.H.5    Ponnudurai, K.6
  • 13
    • 0038040665 scopus 로고    scopus 로고
    • Detection of minimal residual disease in hematologic malignancies by real-time quantitative PCR: principles, approaches, and laboratory aspects
    • PID: 1276436
    • Van der Velden V, Hochhaus A, Cazzaniga G, Szczepanski T, Gabert J, Van Dongen J. Detection of minimal residual disease in hematologic malignancies by real-time quantitative PCR: principles, approaches, and laboratory aspects. Leukemia. 2003;17(6):1013–34.
    • (2003) Leukemia. , vol.17 , Issue.6 , pp. 1013-1034
    • Van der Velden, V.1    Hochhaus, A.2    Cazzaniga, G.3    Szczepanski, T.4    Gabert, J.5    Van Dongen, J.6
  • 14
    • 9144265458 scopus 로고    scopus 로고
    • Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: report of the BIOMED-2 Concerted Action BMH4-CT98-3936
    • PID: 1467165
    • van Dongen J. Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: report of the BIOMED-2 Concerted Action BMH4-CT98-3936. Leukemia. 2003;17:2257–317.
    • (2003) Leukemia. , vol.17 , pp. 2257-2317
    • van Dongen, J.1
  • 15
    • 77955714137 scopus 로고    scopus 로고
    • Preemptive alloimmune intervention in high-risk pediatric acute lymphoblastic leukemia patients guided by minimal residual disease level before stem cell transplantation
    • COI: 1:CAS:528:DC%2BC3cXhtVSmur%2F
    • Lankester A, Bierings M, van Wering E, Wijkhuijs A, de Weger R, Wijnen J, et al. Preemptive alloimmune intervention in high-risk pediatric acute lymphoblastic leukemia patients guided by minimal residual disease level before stem cell transplantation. Leukemia (08876924). 2010;24(8):1462–9.
    • (2010) Leukemia (08876924). , vol.24 , Issue.8 , pp. 1462-1469
    • Lankester, A.1    Bierings, M.2    van Wering, E.3    Wijkhuijs, A.4    de Weger, R.5    Wijnen, J.6
  • 16
    • 42349085052 scopus 로고    scopus 로고
    • Minimal residual disease-directed risk stratification using real-time quantitative PCR analysis of immunoglobulin and T-cell receptor gene rearrangements in the international multicenter trial AIEOP-BFM ALL 2000 for childhood acute lymphoblastic leukemia
    • PID: 18239620, COI: 1:CAS:528:DC%2BD1cXks12rtbc%3
    • Flohr T, Schrauder A, Cazzaniga G, Panzer-Grümayer R, van der Velden V, Fischer S, et al. Minimal residual disease-directed risk stratification using real-time quantitative PCR analysis of immunoglobulin and T-cell receptor gene rearrangements in the international multicenter trial AIEOP-BFM ALL 2000 for childhood acute lymphoblastic leukemia. Leukemia. 2008;22(4):771–82.
    • (2008) Leukemia. , vol.22 , Issue.4 , pp. 771-782
    • Flohr, T.1    Schrauder, A.2    Cazzaniga, G.3    Panzer-Grümayer, R.4    van der Velden, V.5    Fischer, S.6
  • 17
    • 66149141393 scopus 로고    scopus 로고
    • Improved risk classification for risk-specific therapy based on the molecular study of minimal residual disease (MRD) in adult acute lymphoblastic leukemia (ALL)
    • PID: 19141862, COI: 1:CAS:528:DC%2BD1MXlvVGis7c%3
    • Bassan R, Spinelli O, Oldani E, Intermesoli T, Tosi M, Peruta B, et al. Improved risk classification for risk-specific therapy based on the molecular study of minimal residual disease (MRD) in adult acute lymphoblastic leukemia (ALL). Blood. 2009;113(18):4153–62.
    • (2009) Blood. , vol.113 , Issue.18 , pp. 4153-4162
    • Bassan, R.1    Spinelli, O.2    Oldani, E.3    Intermesoli, T.4    Tosi, M.5    Peruta, B.6
  • 18
    • 77949424466 scopus 로고    scopus 로고
    • Standardized MRD quantification in European ALL trials: proceedings of the second international symposium on MRD assessment in Kiel, Germany, 18–20 September 2008
    • PID: 2003305
    • Brüggemann M, Schrauder A, Raff T, Pfeifer H, Dworzak M, Ottmann O, et al. Standardized MRD quantification in European ALL trials: proceedings of the second international symposium on MRD assessment in Kiel, Germany, 18–20 September 2008. Leukemia. 2010;24(3):521–35.
    • (2010) Leukemia. , vol.24 , Issue.3 , pp. 521-535
    • Brüggemann, M.1    Schrauder, A.2    Raff, T.3    Pfeifer, H.4    Dworzak, M.5    Ottmann, O.6
  • 19
    • 84875673056 scopus 로고    scopus 로고
    • Breakpoint-specific multiplex polymerase chain reaction allows the detection of IKZF1 intragenic deletions and minimal residual disease monitoring in B-cell precursor acute lymphoblastic leukemia
    • PID: 23065506, COI: 1:CAS:528:DC%2BC3sXhsFWnu7r
    • Caye A, Beldjord K, Mass-Malo K, Drunat S, Soulier J, Gandemer V, et al. Breakpoint-specific multiplex polymerase chain reaction allows the detection of IKZF1 intragenic deletions and minimal residual disease monitoring in B-cell precursor acute lymphoblastic leukemia. Haematologica. 2013;98(4):597–601.
    • (2013) Haematologica. , vol.98 , Issue.4 , pp. 597-601
    • Caye, A.1    Beldjord, K.2    Mass-Malo, K.3    Drunat, S.4    Soulier, J.5    Gandemer, V.6
  • 20
    • 33947362505 scopus 로고    scopus 로고
    • Analysis of minimal residual disease by Ig/TCR gene rearrangements: guidelines for interpretation of real-time quantitative PCR data
    • PID: 17287850, COI: 1:CAS:528:DC%2BD2sXjt1Wku7s%3
    • Van der Velden V, Cazzaniga G, Schrauder A, Hancock J, Bader P, Panzer-Grumayer E, et al. Analysis of minimal residual disease by Ig/TCR gene rearrangements: guidelines for interpretation of real-time quantitative PCR data. Leukemia. 2007;21(4):604–11.
    • (2007) Leukemia. , vol.21 , Issue.4 , pp. 604-611
    • Van der Velden, V.1    Cazzaniga, G.2    Schrauder, A.3    Hancock, J.4    Bader, P.5    Panzer-Grumayer, E.6
  • 21
    • 58149331359 scopus 로고    scopus 로고
    • Standardization of flow cytometric minimal residual disease evaluation in acute lymphoblastic leukemia: multicentric assessment is feasible
    • Dworzak MN, Gaipa G, Ratei R, Veltroni M, Schumich A, Maglia O, et al. Standardization of flow cytometric minimal residual disease evaluation in acute lymphoblastic leukemia: multicentric assessment is feasible. Cytom Part B Clin Cytom. 2008;74(6):331–40.
    • (2008) Cytom Part B Clin Cytom. , vol.74 , Issue.6 , pp. 331-340
    • Dworzak, M.N.1    Gaipa, G.2    Ratei, R.3    Veltroni, M.4    Schumich, A.5    Maglia, O.6
  • 22
    • 0033902614 scopus 로고    scopus 로고
    • Improved assessment of minimal residual disease in B cell malignancies using fluorogenic consensus probes for real-time quantitative PCR
    • Brüggemann M, Droese J, Bolz I, Lüth P, Pott C, Von Neuhoff N, et al. Improved assessment of minimal residual disease in B cell malignancies using fluorogenic consensus probes for real-time quantitative PCR. Leukemia (08876924). 2000;14(8):1419–25.
    • (2000) Leukemia (08876924). , vol.14 , Issue.8 , pp. 1419-1425
    • Brüggemann, M.1    Droese, J.2    Bolz, I.3    Lüth, P.4    Pott, C.5    Von Neuhoff, N.6
  • 23
    • 0034850655 scopus 로고    scopus 로고
    • WillemseM, Van Wering E, Van Weerden J, Kamps W, Van Dongen J. Precursor-B-ALL with D H-J H gene rearrangements have an immature immunogenotype with a high frequency of oligoclonality and hyperdiploidy of chromosome 14
    • Szczepański T. WillemseM, Van Wering E, Van Weerden J, Kamps W, Van Dongen J. Precursor-B-ALL with D H-J H gene rearrangements have an immature immunogenotype with a high frequency of oligoclonality and hyperdiploidy of chromosome 14. Leukemia (08876924). 2001;15(9):1415–23.
    • (2001) Leukemia (08876924). , vol.15 , Issue.9 , pp. 1415-1423
    • Szczepański, T.1
  • 24
    • 0036248389 scopus 로고    scopus 로고
    • Low frequency of clonotypic Ig and T‐cell receptor gene rearrangements in t (4; 11) infant acute lymphoblastic leukaemia and its implication for the detection of minimal residual disease
    • PID: 11972513, COI: 1:CAS:528:DC%2BD38XkvVGltbc%3
    • Peham M, Panzer S, Fasching K, Haas OA, Fischer S, Marschalek R, et al. Low frequency of clonotypic Ig and T‐cell receptor gene rearrangements in t (4; 11) infant acute lymphoblastic leukaemia and its implication for the detection of minimal residual disease. Br J Haematol. 2002;117(2):315–21.
    • (2002) Br J Haematol. , vol.117 , Issue.2 , pp. 315-321
    • Peham, M.1    Panzer, S.2    Fasching, K.3    Haas, O.A.4    Fischer, S.5    Marschalek, R.6
  • 25
    • 0036009608 scopus 로고    scopus 로고
    • Molecular monitoring of residual disease using antigen receptor genes in childhood acute lymphoblastic leukaemia
    • PID: 1198791
    • Szczepański T, Flohr T, van der Velden VH, Bartram CR, van Dongen JJ. Molecular monitoring of residual disease using antigen receptor genes in childhood acute lymphoblastic leukaemia. Best Pract Res Clin Haematol. 2002;15(1):37–57.
    • (2002) Best Pract Res Clin Haematol. , vol.15 , Issue.1 , pp. 37-57
    • Szczepański, T.1    Flohr, T.2    van der Velden, V.H.3    Bartram, C.R.4    van Dongen, J.J.5
  • 26
    • 0036114311 scopus 로고    scopus 로고
    • Immunoglobulin kappa deleting element rearrangements in precursor-B acute lymphoblastic leukemia are stable targetsfor detection of minimal residual disease by real-time quantitative PCR
    • Van der Velden V, Willemse M, Van der Schoot C, Hählen K, Van Wering E, Van Dongen J. Immunoglobulin kappa deleting element rearrangements in precursor-B acute lymphoblastic leukemia are stable targetsfor detection of minimal residual disease by real-time quantitative PCR. Leukemia (08876924). 2002;16(5):928–36.
    • (2002) Leukemia (08876924). , vol.16 , Issue.5 , pp. 928-936
    • Van der Velden, V.1    Willemse, M.2    Van der Schoot, C.3    Hählen, K.4    Van Wering, E.5    Van Dongen, J.6
  • 27
    • 0028670764 scopus 로고    scopus 로고
    • Beishuizen A, Verhoeven MA, Mol EJ, van Dongen JJ. Detection of immunoglobulin kappa light-chain gene rearrangement patterns by Southern blot analysis. Leukemia. 1994; 8(12):2228–36; discussion 37–9
    • Beishuizen A, Verhoeven MA, Mol EJ, van Dongen JJ. Detection of immunoglobulin kappa light-chain gene rearrangement patterns by Southern blot analysis. Leukemia. 1994; 8(12):2228–36; discussion 37–9.
  • 28
    • 0036051771 scopus 로고    scopus 로고
    • T cell receptor gamma gene rearrangements as targets for detection of minimal residual disease in acute lymphoblastic leukemia by real-time quantitative PCR analysis
    • Van der Velden V, Wijkhujis J, Jacobs D, Van Wering E, Van Dongen J. T cell receptor gamma gene rearrangements as targets for detection of minimal residual disease in acute lymphoblastic leukemia by real-time quantitative PCR analysis. Leukemia (08876924). 2002;16(7):1372–80.
    • (2002) Leukemia (08876924). , vol.16 , Issue.7 , pp. 1372-1380
    • Van der Velden, V.1    Wijkhujis, J.2    Jacobs, D.3    Van Wering, E.4    Van Dongen, J.5
  • 29
    • 31344446387 scopus 로고    scopus 로고
    • Rearrangements of IgH, TCRD and TCRG genes as clonality marker of childhood acute lymphoblastic leukemia
    • PID: 16404354, COI: 1:CAS:528:DC%2BD28XhsFehsL4%3
    • Meleshko A, Lipay N, Stasevich I, Potapnev M. Rearrangements of IgH, TCRD and TCRG genes as clonality marker of childhood acute lymphoblastic leukemia. Exp Oncol. 2005;27(4):319–24.
    • (2005) Exp Oncol. , vol.27 , Issue.4 , pp. 319-324
    • Meleshko, A.1    Lipay, N.2    Stasevich, I.3    Potapnev, M.4
  • 30
    • 0033931757 scopus 로고    scopus 로고
    • T cell receptor gamma (TCRG) gene rearrangements in T cell acute lymphoblastic leukemia reflect ‘end-stage’recombinations: implications for minimal residual disease monitoring
    • Szczepański T, Langerak A, Willemse M, Wolvers-Tettero I, Van Wering E, Van Dongen J. T cell receptor gamma (TCRG) gene rearrangements in T cell acute lymphoblastic leukemia reflect ‘end-stage’recombinations: implications for minimal residual disease monitoring. Leukemia (08876924). 2000;14(7):1208–14.
    • (2000) Leukemia (08876924). , vol.14 , Issue.7 , pp. 1208-1214
    • Szczepański, T.1    Langerak, A.2    Willemse, M.3    Wolvers-Tettero, I.4    Van Wering, E.5    Van Dongen, J.6
  • 31
    • 0032855020 scopus 로고    scopus 로고
    • Easy detection of all T cell receptor gamma (TCRG) gene rearrangements by Southern blot analysis: recommendations for optimal results
    • COI: 1:CAS:528:DyaK1MXntVSqtLo%3
    • Moreau E, Langerak A, van Gastel-Mol E, Wolvers-Tettero I, Zhan M, Zhou Q, et al. Easy detection of all T cell receptor gamma (TCRG) gene rearrangements by Southern blot analysis: recommendations for optimal results. Leukemia (08876924). 1999;13(10):1620–6.
    • (1999) Leukemia (08876924). , vol.13 , Issue.10 , pp. 1620-1626
    • Moreau, E.1    Langerak, A.2    van Gastel-Mol, E.3    Wolvers-Tettero, I.4    Zhan, M.5    Zhou, Q.6
  • 32
    • 9144265458 scopus 로고    scopus 로고
    • Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: report of the BIOMED-2 Concerted Action BMH4-CT98-3936
    • PID: 1467165
    • Van Dongen J, Langerak A, Brüggemann M, Evans P, Hummel M, Lavender F, et al. Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: report of the BIOMED-2 Concerted Action BMH4-CT98-3936. Leukemia. 2003;17(12):2257–317.
    • (2003) Leukemia. , vol.17 , Issue.12 , pp. 2257-2317
    • Van Dongen, J.1    Langerak, A.2    Brüggemann, M.3    Evans, P.4    Hummel, M.5    Lavender, F.6
  • 33
    • 33746967636 scopus 로고    scopus 로고
    • Methodological approach to minimal residual disease detection by flow cytometry in adult B-lineage acute lymphoblastic leukemia
    • PID: 1688505
    • Krampera M, Perbellini O, Vincenzi C, Zampieri F, Pasini A, Scupoli MT, et al. Methodological approach to minimal residual disease detection by flow cytometry in adult B-lineage acute lymphoblastic leukemia. Haematologica. 2006;91(8):1109–12.
    • (2006) Haematologica. , vol.91 , Issue.8 , pp. 1109-1112
    • Krampera, M.1    Perbellini, O.2    Vincenzi, C.3    Zampieri, F.4    Pasini, A.5    Scupoli, M.T.6
  • 34
    • 47049093795 scopus 로고    scopus 로고
    • Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia and its relationship to other prognostic factors: a Children’s Oncology Group study
    • PID: 18388178, COI: 1:CAS:528:DC%2BD1cXnsVOkt74%3
    • Borowitz MJ, Devidas M, Hunger SP, Bowman WP, Carroll AJ, Carroll WL, et al. Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia and its relationship to other prognostic factors: a Children’s Oncology Group study. Blood. 2008;111(12):5477–85.
    • (2008) Blood. , vol.111 , Issue.12 , pp. 5477-5485
    • Borowitz, M.J.1    Devidas, M.2    Hunger, S.P.3    Bowman, W.P.4    Carroll, A.J.5    Carroll, W.L.6
  • 35
    • 70449711125 scopus 로고    scopus 로고
    • Risk of relapse of childhood acute lymphoblastic leukemia is predicted by flow cytometric measurement of residual disease on day 15 bone marrow
    • PID: 1980569
    • Basso G, Veltroni M, Valsecchi MG, Dworzak MN, Ratei R, Silvestri D, et al. Risk of relapse of childhood acute lymphoblastic leukemia is predicted by flow cytometric measurement of residual disease on day 15 bone marrow. J Clin Oncol. 2009;27(31):5168–74.
    • (2009) J Clin Oncol. , vol.27 , Issue.31 , pp. 5168-5174
    • Basso, G.1    Veltroni, M.2    Valsecchi, M.G.3    Dworzak, M.N.4    Ratei, R.5    Silvestri, D.6
  • 36
    • 0037085750 scopus 로고    scopus 로고
    • Prognostic significance and modalities of flow cytometric minimal residual disease detection in childhood acute lymphoblastic leukemia
    • PID: 11877265, COI: 1:CAS:528:DC%2BD38XitF2nt70%3
    • Dworzak M. Prognostic significance and modalities of flow cytometric minimal residual disease detection in childhood acute lymphoblastic leukemia. Blood. 2002;99:1952–8.
    • (2002) Blood. , vol.99 , pp. 1952-1958
    • Dworzak, M.1
  • 37
    • 17944380938 scopus 로고    scopus 로고
    • BIOMED-1 concerted action report: flow cytometric immunophenotyping of precursor B-ALL with standardized triple-stainings
    • COI: 1:CAS:528:DC%2BD3MXms1Ort7o%3
    • Lucio P, Gaipa G, Van Lochem E, Van Wering E, Porwit-MacDonald A, Faria T, et al. BIOMED-1 concerted action report: flow cytometric immunophenotyping of precursor B-ALL with standardized triple-stainings. Leukemia (08876924). 2001;15(8):1185–92.
    • (2001) Leukemia (08876924). , vol.15 , Issue.8 , pp. 1185-1192
    • Lucio, P.1    Gaipa, G.2    Van Lochem, E.3    Van Wering, E.4    Porwit-MacDonald, A.5    Faria, T.6
  • 38
    • 7044250032 scopus 로고    scopus 로고
    • CD99 expression in T-lineage ALL: implications for flow cytometric detection of minimal residual disease
    • PID: 14961034, COI: 1:CAS:528:DC%2BD2cXisVyru7c%3
    • Dworzak M, Fröschl G, Printz D, De Zen L, Gaipa G, Ratei R, et al. CD99 expression in T-lineage ALL: implications for flow cytometric detection of minimal residual disease. Leukemia. 2004;18(4):703–8.
    • (2004) Leukemia. , vol.18 , Issue.4 , pp. 703-708
    • Dworzak, M.1    Fröschl, G.2    Printz, D.3    De Zen, L.4    Gaipa, G.5    Ratei, R.6
  • 39
    • 0031956480 scopus 로고    scopus 로고
    • Comparative phenotype mapping of normal vs. malignant pediatric B-lymphopoiesis unveils leukemia-associated aberrations
    • PID: 9546313, COI: 1:STN:280:DyaK1c3gs1eruw%3D%3
    • Dworzak M, Fritsch G, Fleischer C, Printz D, Fröschl G, Buchinger P, et al. Comparative phenotype mapping of normal vs. malignant pediatric B-lymphopoiesis unveils leukemia-associated aberrations. Exp Hematol. 1998;26(4):305–13.
    • (1998) Exp Hematol. , vol.26 , Issue.4 , pp. 305-313
    • Dworzak, M.1    Fritsch, G.2    Fleischer, C.3    Printz, D.4    Fröschl, G.5    Buchinger, P.6
  • 40
    • 0032770146 scopus 로고    scopus 로고
    • Detection of minimal residual disease in acute leukemia by flow cytometry
    • PID: 10440852, COI: 1:STN:280:DyaK1MzmvFOksg%3D%3
    • Campana D, Coustan-Smith E. Detection of minimal residual disease in acute leukemia by flow cytometry. Cytometry. 1999;38(4):139–52.
    • (1999) Cytometry. , vol.38 , Issue.4 , pp. 139-152
    • Campana, D.1    Coustan-Smith, E.2
  • 41
    • 0032957090 scopus 로고    scopus 로고
    • A limited antibody panel can distinguish B-precursor acute lymphoblastic leukemia from normal B precursors with four color flow cytometry: implications for residual disease detection
    • COI: 1:STN:280:DyaK1M3ivFKktw%3D%3
    • Weir E, Cowan K, LeBeau P, Borowitz M. A limited antibody panel can distinguish B-precursor acute lymphoblastic leukemia from normal B precursors with four color flow cytometry: implications for residual disease detection. Leukemia (08876924). 1999;13(4):558–67.
    • (1999) Leukemia (08876924). , vol.13 , Issue.4 , pp. 558-567
    • Weir, E.1    Cowan, K.2    LeBeau, P.3    Borowitz, M.4
  • 42
    • 0344823957 scopus 로고    scopus 로고
    • Expression of CD58 in normal, regenerating and leukemic bone marrow B cells: implications for the detection of minimal residual disease in acute lymphocytic leukemia
    • PID: 1460775
    • Veltroni M, De Zen L, Sanzari MC, Maglia O, Dworzak MN, Ratei R, et al. Expression of CD58 in normal, regenerating and leukemic bone marrow B cells: implications for the detection of minimal residual disease in acute lymphocytic leukemia. Haematologica. 2003;88(11):1245–52.
    • (2003) Haematologica. , vol.88 , Issue.11 , pp. 1245-1252
    • Veltroni, M.1    De Zen, L.2    Sanzari, M.C.3    Maglia, O.4    Dworzak, M.N.5    Ratei, R.6
  • 43
    • 0034667685 scopus 로고    scopus 로고
    • Clinical importance of minimal residual disease in childhood acute lymphoblastic leukemia
    • PID: 11023499, COI: 1:CAS:528:DC%2BD3cXnt12gsLY%3
    • Coustan-Smith E, Sancho J, Hancock ML, Boyett JM, Behm FG, Raimondi SC, et al. Clinical importance of minimal residual disease in childhood acute lymphoblastic leukemia. Blood. 2000;96(8):2691–6.
    • (2000) Blood. , vol.96 , Issue.8 , pp. 2691-2696
    • Coustan-Smith, E.1    Sancho, J.2    Hancock, M.L.3    Boyett, J.M.4    Behm, F.G.5    Raimondi, S.C.6
  • 45
    • 0037560363 scopus 로고    scopus 로고
    • Flow cytometric detection of minimal residual disease in acute lymphoblastic leukemia
    • PID: 1456564
    • Dworzak MN, Panzer-Grümayer ER. Flow cytometric detection of minimal residual disease in acute lymphoblastic leukemia. Leuk Lymphoma. 2003;44(9):1445–55.
    • (2003) Leuk Lymphoma. , vol.44 , Issue.9 , pp. 1445-1455
    • Dworzak, M.N.1    Panzer-Grümayer, E.R.2
  • 46
    • 0035128917 scopus 로고    scopus 로고
    • Quantification of minimal residual disease in children with oligoclonal B-precursor acute lymphoblastic leukemia indicates that the clones that grow out during relapse already have the slowest rate of reduction during induction therapy
    • De Haas V, Verhagen O, von dem Borne A, Kroes W, Van Den Berg H, Van Der Schoot C. Quantification of minimal residual disease in children with oligoclonal B-precursor acute lymphoblastic leukemia indicates that the clones that grow out during relapse already have the slowest rate of reduction during induction therapy. Leukemia. 2001;15(1):134–40.
    • (2001) Leukemia , vol.15 , Issue.1 , pp. 134-140
    • De Haas, V.1    Verhagen, O.2    von dem Borne, A.3    Kroes, W.4    Van Den Berg, H.5    Van Der Schoot, C.6
  • 47
    • 0036660158 scopus 로고    scopus 로고
    • Prognostic importance of measuring early clearance of leukemic cells by flow cytometry in childhood acute lymphoblastic leukemia
    • PID: 12070008, COI: 1:CAS:528:DC%2BD38XltF2rs7s%3
    • Coustan-Smith E, Sancho J, Behm FG, Hancock ML, Razzouk BI, Ribeiro RC, et al. Prognostic importance of measuring early clearance of leukemic cells by flow cytometry in childhood acute lymphoblastic leukemia. Blood. 2002;100(1):52–8.
    • (2002) Blood. , vol.100 , Issue.1 , pp. 52-58
    • Coustan-Smith, E.1    Sancho, J.2    Behm, F.G.3    Hancock, M.L.4    Razzouk, B.I.5    Ribeiro, R.C.6
  • 48
    • 77951441599 scopus 로고    scopus 로고
    • Molecular response to treatment redefines all prognostic factors in children and adolescents with B-cell precursor acute lymphoblastic leukemia: results in 3184 patients of the AIEOP-BFM ALL 2000 study
    • PID: 20154213, COI: 1:CAS:528:DC%2BC3cXlvVags7w%3
    • Conter V, Bartram CR, Valsecchi MG, Schrauder A, Panzer-Grümayer R, Möricke A, et al. Molecular response to treatment redefines all prognostic factors in children and adolescents with B-cell precursor acute lymphoblastic leukemia: results in 3184 patients of the AIEOP-BFM ALL 2000 study. Blood. 2010;115(16):3206–14.
    • (2010) Blood. , vol.115 , Issue.16 , pp. 3206-3214
    • Conter, V.1    Bartram, C.R.2    Valsecchi, M.G.3    Schrauder, A.4    Panzer-Grümayer, R.5    Möricke, A.6
  • 49
    • 80052172961 scopus 로고    scopus 로고
    • Late MRD response determines relapse risk overall and in subsets of childhood T-cell ALL: results of the AIEOP-BFM-ALL 2000 study
    • PID: 21719599, COI: 1:CAS:528:DC%2BC3MXhtFGisrn
    • Schrappe M, Valsecchi MG, Bartram CR, Schrauder A, Panzer-Grümayer R, Möricke A, et al. Late MRD response determines relapse risk overall and in subsets of childhood T-cell ALL: results of the AIEOP-BFM-ALL 2000 study. Blood. 2011;118(8):2077–84.
    • (2011) Blood. , vol.118 , Issue.8 , pp. 2077-2084
    • Schrappe, M.1    Valsecchi, M.G.2    Bartram, C.R.3    Schrauder, A.4    Panzer-Grümayer, R.5    Möricke, A.6
  • 50
    • 34548817262 scopus 로고    scopus 로고
    • Quantitative analysis of minimal residual disease predicts relapse in children with B-lineage acute lymphoblastic leukemia in DFCI ALL Consortium Protocol 95-01
    • PID: 17485550, COI: 1:CAS:528:DC%2BD2sXhtVSgsbv
    • Zhou J, Goldwasser MA, Li A, Dahlberg SE, Neuberg D, Wang H, et al. Quantitative analysis of minimal residual disease predicts relapse in children with B-lineage acute lymphoblastic leukemia in DFCI ALL Consortium Protocol 95-01. Blood. 2007;110(5):1607–11.
    • (2007) Blood. , vol.110 , Issue.5 , pp. 1607-1611
    • Zhou, J.1    Goldwasser, M.A.2    Li, A.3    Dahlberg, S.E.4    Neuberg, D.5    Wang, H.6
  • 51
    • 0036786910 scopus 로고    scopus 로고
    • Use of peripheral blood instead of bone marrow to monitor residual disease in children with acute lymphoblastic leukemia
    • PID: 12239148, COI: 1:CAS:528:DC%2BD38XnvVGisL4%3
    • Coustan-Smith E, Sancho J, Hancock ML, Razzouk BI, Ribeiro RC, Rivera GK, et al. Use of peripheral blood instead of bone marrow to monitor residual disease in children with acute lymphoblastic leukemia. Blood. 2002;100(7):2399–402.
    • (2002) Blood. , vol.100 , Issue.7 , pp. 2399-2402
    • Coustan-Smith, E.1    Sancho, J.2    Hancock, M.L.3    Razzouk, B.I.4    Ribeiro, R.C.5    Rivera, G.K.6
  • 52
    • 27644558593 scopus 로고    scopus 로고
    • Comparison of diagnostic and relapse flow cytometry phenotypes in childhood acute lymphoblastic leukemia: implications for residual disease detection: a report from the children’s oncology group
    • Borowitz MJ, Pullen DJ, Winick N, Martin PL, Bowman WP, Camitta B. Comparison of diagnostic and relapse flow cytometry phenotypes in childhood acute lymphoblastic leukemia: implications for residual disease detection: a report from the children’s oncology group. Cytom Part B Clin Cytom. 2005;68(1):18–24.
    • (2005) Cytom Part B Clin Cytom. , vol.68 , Issue.1 , pp. 18-24
    • Borowitz, M.J.1    Pullen, D.J.2    Winick, N.3    Martin, P.L.4    Bowman, W.P.5    Camitta, B.6
  • 53
    • 19944428207 scopus 로고    scopus 로고
    • Drug-induced immunophenotypic modulation in childhood ALL: implications for minimal residual disease detection
    • PID: 15538405, COI: 1:STN:280:DC%2BD2cnhvVKnsA%3D%3
    • Gaipa G, Basso G, Maglia O, Leoni V, Faini A, Cazzaniga G, et al. Drug-induced immunophenotypic modulation in childhood ALL: implications for minimal residual disease detection. Leukemia. 2005;19(1):49–56.
    • (2005) Leukemia. , vol.19 , Issue.1 , pp. 49-56
    • Gaipa, G.1    Basso, G.2    Maglia, O.3    Leoni, V.4    Faini, A.5    Cazzaniga, G.6
  • 54
    • 30444437486 scopus 로고    scopus 로고
    • Treatment of acute lymphoblastic leukemia
    • PID: 16407512, COI: 1:CAS:528:DC%2BD28XisFWksQ%3D%3
    • Pui C-H, Evans WE. Treatment of acute lymphoblastic leukemia. N Engl J Med. 2006;354(2):166–78.
    • (2006) N Engl J Med. , vol.354 , Issue.2 , pp. 166-178
    • Pui, C.-H.1    Evans, W.E.2
  • 55
    • 47049093795 scopus 로고    scopus 로고
    • Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia and its relationship to other prognostic factors: a Children’s Oncology Group study
    • Borowitz MJ, Devidas M, Hunger SP, Bowman WP, Carroll AJ, Carroll WL, et al. Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia and its relationship to other prognostic factors: a Children’s Oncology Group study. Blood. 2008 Jun 15;111(12):5477-85.
    • (2008) Blood , vol.111 , Issue.12 , pp. 5477-5485
    • Borowitz, M.J.1    Devidas, M.2    Hunger, S.P.3    Bowman, W.P.4    Carroll, A.J.5    Carroll, W.L.6
  • 56
    • 42349085052 scopus 로고    scopus 로고
    • Minimal residual disease-directed risk stratification using real-time quantitative PCR analysis of immunoglobulin and T-cell receptor gene rearrangements in the international multicenter trial AIEOP-BFM ALL 2000 for childhood acute lymphoblastic leukemia
    • PID: 18239620, COI: 1:CAS:528:DC%2BD1cXks12rtbc%3
    • Flohr T, Schrauder A, Cazzaniga G, Panzer-Grümayer R, Van Der Velden V, Fischer S, et al. Minimal residual disease-directed risk stratification using real-time quantitative PCR analysis of immunoglobulin and T-cell receptor gene rearrangements in the international multicenter trial AIEOP-BFM ALL 2000 for childhood acute lymphoblastic leukemia. Leukemia. 2008;22(4):771–82.
    • (2008) Leukemia. , vol.22 , Issue.4 , pp. 771-782
    • Flohr, T.1    Schrauder, A.2    Cazzaniga, G.3    Panzer-Grümayer, R.4    Van Der Velden, V.5    Fischer, S.6
  • 58
    • 57449097398 scopus 로고    scopus 로고
    • Minimal residual disease detection in childhood acute lymphoblastic leukaemia patients at multiple time-points reveals high levels of concordance between molecular and immunophenotypic approaches
    • PID: 1901672
    • Ryan J, Quinn F, Meunier A, Boublikova L, Crampe M, Tewari P, et al. Minimal residual disease detection in childhood acute lymphoblastic leukaemia patients at multiple time-points reveals high levels of concordance between molecular and immunophenotypic approaches. Br J Haematol. 2009;144(1):107–15.
    • (2009) Br J Haematol. , vol.144 , Issue.1 , pp. 107-115
    • Ryan, J.1    Quinn, F.2    Meunier, A.3    Boublikova, L.4    Crampe, M.5    Tewari, P.6
  • 59
    • 70449711125 scopus 로고    scopus 로고
    • Risk of relapse of childhood acute lymphoblastic leukemia is predicted by flow cytometric measurement of residual disease on day 15 bone marrow
    • PID: 1980569
    • Basso G, Veltroni M, Grazia Valsecchi M, Dworzak MN, Ratei R, D Silvestri, et al. Risk of relapse of childhood acute lymphoblastic leukemia is predicted by flow cytometric measurement of residual disease on day 15 bone marrow. J Clin Oncol. 2009;27(31):5168–74.
    • (2009) J Clin Oncol , vol.27 , Issue.31 , pp. 5168-5174
    • Basso, G.1    Veltroni, M.2    Grazia Valsecchi, M.3    Dworzak, M.N.4    Ratei, R.5    D, S.6
  • 60
    • 0038715051 scopus 로고    scopus 로고
    • Assessment of clonal stability of minimal residual disease targets between 1st and 2nd relapse of childhood precursor B-cell acute lymphoblastic leukemia
    • PID: 12857551, COI: 1:CAS:528:DC%2BD3sXntFOrt7g%3
    • Guggemos A, Eckert C, Szczepanski T, Hanel C, Taube T, van der Velden V, et al. Assessment of clonal stability of minimal residual disease targets between 1st and 2nd relapse of childhood precursor B-cell acute lymphoblastic leukemia. Haematologica. 2003;88(7):737–46.
    • (2003) Haematologica. , vol.88 , Issue.7 , pp. 737-746
    • Guggemos, A.1    Eckert, C.2    Szczepanski, T.3    Hanel, C.4    Taube, T.5    van der Velden, V.6
  • 61
    • 84869826772 scopus 로고    scopus 로고
    • Massive evolution of the immunoglobulin heavy chain locus in children with B precursor acute lymphoblastic leukemia
    • PID: 22932801, COI: 1:CAS:528:DC%2BC38XhslOqu7z
    • Gawad C, Pepin F, Carlton VE, Klinger M, Logan AC, Miklos DB, et al. Massive evolution of the immunoglobulin heavy chain locus in children with B precursor acute lymphoblastic leukemia. Blood. 2012;120(22):4407–17.
    • (2012) Blood. , vol.120 , Issue.22 , pp. 4407-4417
    • Gawad, C.1    Pepin, F.2    Carlton, V.E.3    Klinger, M.4    Logan, A.C.5    Miklos, D.B.6
  • 62
    • 0037082505 scopus 로고    scopus 로고
    • Precise quantification of minimal residual disease at day 29 allows identification of children with acute lymphoblastic leukemia and anexcellent outcome
    • PID: 11830473, COI: 1:CAS:528:DC%2BD38XhtlWqsb0%3
    • Nyvold C. Precise quantification of minimal residual disease at day 29 allows identification of children with acute lymphoblastic leukemia and anexcellent outcome. Blood. 2002;99:1253–8.
    • (2002) Blood. , vol.99 , pp. 1253-1258
    • Nyvold, C.1
  • 64
    • 27644558593 scopus 로고    scopus 로고
    • Comparisonof diagnostic and relapse flow cytometry phenotypes in childhood acute lymphoblastic leukemia: implications for residual disease detection: a report from the children’s oncology group
    • Borowitz M, Pullen D, Winick N, Martin P, Bowman W, Camitta B. Comparisonof diagnostic and relapse flow cytometry phenotypes in childhood acute lymphoblastic leukemia: implications for residual disease detection: a report from the children’s oncology group. Cytom Part B Clin Cytom. 2005;68(1):18–24.
    • (2005) Cytom Part B Clin Cytom. , vol.68 , Issue.1 , pp. 18-24
    • Borowitz, M.1    Pullen, D.2    Winick, N.3    Martin, P.4    Bowman, W.5    Camitta, B.6
  • 65
    • 0030886271 scopus 로고    scopus 로고
    • Multiparameter phenotype mapping of normal and post-chemotherapy B lymphopoiesis in pediatric bone marrow
    • COI: 1:STN:280:DyaK2svgslKgsw%3D%3
    • Dworzak M, Fritsch G, Fleischer C, Printz D, Fröschl G, Buchinger P, et al. Multiparameter phenotype mapping of normal and post-chemotherapy B lymphopoiesis in pediatric bone marrow. Leukemia (08876924). 1997;11(8):1266–73.
    • (1997) Leukemia (08876924). , vol.11 , Issue.8 , pp. 1266-1273
    • Dworzak, M.1    Fritsch, G.2    Fleischer, C.3    Printz, D.4    Fröschl, G.5    Buchinger, P.6
  • 66
    • 0035889131 scopus 로고    scopus 로고
    • Immunophenotypic analysis of hematogones (B-lymphocyte precursors) in 662 consecutive bone marrow specimens by 4-color flow cytometry
    • PID: 11588048, COI: 1:CAS:528:DC%2BD3MXnslCqs7s%3
    • McKenna RW, Washington LT, Aquino DB, Picker LJ, Kroft SH. Immunophenotypic analysis of hematogones (B-lymphocyte precursors) in 662 consecutive bone marrow specimens by 4-color flow cytometry. Blood. 2001;98(8):2498–507.
    • (2001) Blood. , vol.98 , Issue.8 , pp. 2498-2507
    • McKenna, R.W.1    Washington, L.T.2    Aquino, D.B.3    Picker, L.J.4    Kroft, S.H.5
  • 67
    • 77952570617 scopus 로고    scopus 로고
    • CD11b is a therapy resistance-and minimal residual disease—specific marker in precursor B-cell acute lymphoblastic leukemia
    • PID: 20228269, COI: 1:CAS:528:DC%2BC3cXms1egu7Y%3
    • Rhein P, Mitlohner R, Basso G, Gaipa G, Dworzak MN, Kirschner-Schwabe R, et al. CD11b is a therapy resistance-and minimal residual disease—specific marker in precursor B-cell acute lymphoblastic leukemia. Blood. 2010;115(18):3763–71.
    • (2010) Blood. , vol.115 , Issue.18 , pp. 3763-3771
    • Rhein, P.1    Mitlohner, R.2    Basso, G.3    Gaipa, G.4    Dworzak, M.N.5    Kirschner-Schwabe, R.6
  • 68
    • 66249133415 scopus 로고    scopus 로고
    • Overexpression of CD49f in precursor B-cell acute lymphoblastic leukemia: Potential usefulness in minimal residual disease detection
    • DiGiuseppe JA, Fuller SG, Borowitz MJ. Overexpression of CD49f in precursor B-cell acute lymphoblastic leukemia: Potential usefulness in minimal residual disease detection. Cytom Part B Clin Cytom. 2009;76(2):150–5.
    • (2009) Cytom Part B Clin Cytom. , vol.76 , Issue.2 , pp. 150-155
    • DiGiuseppe, J.A.1    Fuller, S.G.2    Borowitz, M.J.3
  • 69
    • 70449721037 scopus 로고    scopus 로고
    • Aberrant underexpression of CD81 in precursor B-cell acute lymphoblastic leukemia utility in detection of minimal residual disease by flow cytometry
    • PID: 1984680
    • Muzzafar T, Medeiros LJ, Wang SA, Brahmandam A, Thomas DA, Jorgensen JL. Aberrant underexpression of CD81 in precursor B-cell acute lymphoblastic leukemia utility in detection of minimal residual disease by flow cytometry. Am J Clin Pathol. 2009;132(5):692–8.
    • (2009) Am J Clin Pathol. , vol.132 , Issue.5 , pp. 692-698
    • Muzzafar, T.1    Medeiros, L.J.2    Wang, S.A.3    Brahmandam, A.4    Thomas, D.A.5    Jorgensen, J.L.6
  • 70
    • 2342540402 scopus 로고    scopus 로고
    • Comparative analysis of flow cytometry and polymerase chain reaction for the detection of minimal residual disease in childhood acute lymphoblastic leukemia
    • PID: 15029212, COI: 1:CAS:528:DC%2BD2cXjtlyitLg%3
    • Neale G, Coustan-Smith E, Stow P, Pan Q, Chen X, Pui C, et al. Comparative analysis of flow cytometry and polymerase chain reaction for the detection of minimal residual disease in childhood acute lymphoblastic leukemia. Leukemia. 2004;18(5):934–8.
    • (2004) Leukemia. , vol.18 , Issue.5 , pp. 934-938
    • Neale, G.1    Coustan-Smith, E.2    Stow, P.3    Pan, Q.4    Chen, X.5    Pui, C.6
  • 71
    • 0141725588 scopus 로고    scopus 로고
    • Age-related patterns of immunoglobulin and T-cell receptor gene rearrangements in precursor-B-ALL: implications for detection of minimal residual disease
    • PID: 1297078
    • Van der Velden V, Szczepanski T, Wijkhuijs J, Hart P, Hoogeveen P, Hop W, et al. Age-related patterns of immunoglobulin and T-cell receptor gene rearrangements in precursor-B-ALL: implications for detection of minimal residual disease. Leukemia. 2003;17(9):1834–44.
    • (2003) Leukemia. , vol.17 , Issue.9 , pp. 1834-1844
    • Van der Velden, V.1    Szczepanski, T.2    Wijkhuijs, J.3    Hart, P.4    Hoogeveen, P.5    Hop, W.6
  • 72
    • 5744223871 scopus 로고    scopus 로고
    • Analysis of minimal residual disease in childhood acute lymphoblastic leukemia: comparison between RQ-PCR analysis of Ig/TcR gene rearrangements and multicolor flow cytometric immunophenotyping
    • PID: 15295608, COI: 1:CAS:528:DC%2BD2cXnvV2qsLs%3
    • Malec M, Van der Velden V, Björklund E, Wijkhuijs J, Söderhäll S, Mazur J, et al. Analysis of minimal residual disease in childhood acute lymphoblastic leukemia: comparison between RQ-PCR analysis of Ig/TcR gene rearrangements and multicolor flow cytometric immunophenotyping. Leukemia. 2004;18(10):1630–6.
    • (2004) Leukemia. , vol.18 , Issue.10 , pp. 1630-1636
    • Malec, M.1    Van der Velden, V.2    Björklund, E.3    Wijkhuijs, J.4    Söderhäll, S.5    Mazur, J.6
  • 73
    • 33947381440 scopus 로고    scopus 로고
    • Optimization of PCR-based minimal residual disease diagnostics for childhood acute lymphoblastic leukemia in a multi-center setting
    • PID: 1728785
    • Van der Velden V, Panzer-Grümayer E, Cazzaniga G, Flohr T, Sutton R, Schrauder A, et al. Optimization of PCR-based minimal residual disease diagnostics for childhood acute lymphoblastic leukemia in a multi-center setting. Leukemia. 2007;21(4):706–13.
    • (2007) Leukemia. , vol.21 , Issue.4 , pp. 706-713
    • Van der Velden, V.1    Panzer-Grümayer, E.2    Cazzaniga, G.3    Flohr, T.4    Sutton, R.5    Schrauder, A.6
  • 74
    • 38349143355 scopus 로고    scopus 로고
    • Long-term results of the AIEOP-ALL-95 trial for childhood acute lymphoblastic leukemia: insight on the prognostic value of DNA index in the framework of berlin-frankfurt-muenster-based chemotherapy
    • PID: 1818266
    • Aricò M, Valsecchi MG, Rizzari C, Barisone E, Biondi A, Casale F, et al. Long-term results of the AIEOP-ALL-95 trial for childhood acute lymphoblastic leukemia: insight on the prognostic value of DNA index in the framework of berlin-frankfurt-muenster-based chemotherapy. J Clin Oncol. 2008;26(2):283–9.
    • (2008) J Clin Oncol. , vol.26 , Issue.2 , pp. 283-289
    • Aricò, M.1    Valsecchi, M.G.2    Rizzari, C.3    Barisone, E.4    Biondi, A.5    Casale, F.6
  • 75
    • 66749117163 scopus 로고    scopus 로고
    • Establishment and validation of a standard protocol for the detection of minimal residual disease in B lineage childhood acute lymphoblastic leukemia by flow cytometry in a multi-center setting
    • PID: 1937707
    • Irving J, Jesson J, Virgo P, Case M, Minto L, Eyre L, et al. Establishment and validation of a standard protocol for the detection of minimal residual disease in B lineage childhood acute lymphoblastic leukemia by flow cytometry in a multi-center setting. Haematologica. 2009;94(6):870–4.
    • (2009) Haematologica. , vol.94 , Issue.6 , pp. 870-874
    • Irving, J.1    Jesson, J.2    Virgo, P.3    Case, M.4    Minto, L.5    Eyre, L.6
  • 77
    • 0032757710 scopus 로고    scopus 로고
    • Standardized RT-PCR analysis of fusion gene transcripts from chromosome aberrations in acute leukemia for detection of minimal residual disease
    • Van Dongen J, Macintyre E, Gabert J, Delabesse E, Rossi V, Saglio G, et al. Standardized RT-PCR analysis of fusion gene transcripts from chromosome aberrations in acute leukemia for detection of minimal residual disease. Leukemia (08876924). 1999;13(12):1901–28.
    • (1999) Leukemia (08876924). , vol.13 , Issue.12 , pp. 1901-1928
    • Van Dongen, J.1    Macintyre, E.2    Gabert, J.3    Delabesse, E.4    Rossi, V.5    Saglio, G.6
  • 78
    • 78349293365 scopus 로고    scopus 로고
    • Prospective comparison of two flow cytometry methodologies for monitoring minimal residual disease in a multicenter treatment protocol of childhood acute lymphoblastic leukemia
    • Luria D, Rosenthal E, Steinberg D, Kodman Y, Safanaiev M, Amariglio N, et al. Prospective comparison of two flow cytometry methodologies for monitoring minimal residual disease in a multicenter treatment protocol of childhood acute lymphoblastic leukemia. Cytom Part B Clin Cytom. 2010;78(6):365–71.
    • (2010) Cytom Part B Clin Cytom. , vol.78 , Issue.6 , pp. 365-371
    • Luria, D.1    Rosenthal, E.2    Steinberg, D.3    Kodman, Y.4    Safanaiev, M.5    Amariglio, N.6
  • 79
    • 27844468129 scopus 로고    scopus 로고
    • Four-color flow cytometry bypasses limitations of IG/TCR polymerase chain reaction for minimal residual disease detection in certain subsets of children with acute lymphoblastic leukemia
    • PID: 16266899, COI: 1:CAS:528:DC%2BD2MXht12qtLr
    • Robillard N, Cavé H, Méchinaud F, Guidal C, Garnache-Ottou F, Rohrlich PS, et al. Four-color flow cytometry bypasses limitations of IG/TCR polymerase chain reaction for minimal residual disease detection in certain subsets of children with acute lymphoblastic leukemia. Haematologica. 2005;90(11):1516–23.
    • (2005) Haematologica. , vol.90 , Issue.11 , pp. 1516-1523
    • Robillard, N.1    Cavé, H.2    Méchinaud, F.3    Guidal, C.4    Garnache-Ottou, F.5    Rohrlich, P.S.6
  • 80
    • 84919910429 scopus 로고    scopus 로고
    • Gaipa G, Cazzaniga G, Valsecchi MG, Panzer-Grümayer R, Buldini B, Silvestri D, et al. Time point-dependent concordance of flow cytometry and RQ-PCR in minimal residual disease detection in childhood acute lymphoblastic leukemia. Haematologica. 2012: Haematologica. 2011.060426
    • Gaipa G, Cazzaniga G, Valsecchi MG, Panzer-Grümayer R, Buldini B, Silvestri D, et al. Time point-dependent concordance of flow cytometry and RQ-PCR in minimal residual disease detection in childhood acute lymphoblastic leukemia. Haematologica. 2012: Haematologica. 2011.060426
  • 81
    • 40749122967 scopus 로고    scopus 로고
    • Non-specific amplification of patient-specific Ig/TCR gene rearrangements depends on the time point during therapy: implications for minimal residual disease monitoring
    • PID: 1785155
    • Van der Velden V, Wijkhuijs J, Van Dongen J. Non-specific amplification of patient-specific Ig/TCR gene rearrangements depends on the time point during therapy: implications for minimal residual disease monitoring. Leukemia. 2008;22(3):641–4.
    • (2008) Leukemia. , vol.22 , Issue.3 , pp. 641-644
    • Van der Velden, V.1    Wijkhuijs, J.2    Van Dongen, J.3
  • 82
    • 0035105325 scopus 로고    scopus 로고
    • Detection of minimal residual disease in acute lymphoblastic leukemia: the St Jude experience
    • PID: 11236945, COI: 1:STN:280:DC%2BD3M7otVyksg%3D%3
    • Campana D, Neale G, Coustan-Smith E, Pui C. Detection of minimal residual disease in acute lymphoblastic leukemia: the St Jude experience. Leukemia. 2001;15(2):278–9.
    • (2001) Leukemia. , vol.15 , Issue.2 , pp. 278-279
    • Campana, D.1    Neale, G.2    Coustan-Smith, E.3    Pui, C.4
  • 83
    • 85014425337 scopus 로고    scopus 로고
    • Pattern of immunoglobulin and T-cell receptor-δ/γ gene rearrangements in Iranian children with B-precursor acute lymphoblastic leukemia
    • Poopak B, Saki N, Purfatholah AA, Najmabadi H, Mortazavi Y, Arzanian MT, et al. Pattern of immunoglobulin and T-cell receptor-δ/γ gene rearrangements in Iranian children with B-precursor acute lymphoblastic leukemia. Hematology. 2013.
    • (2013) Hematology
    • Poopak, B.1    Saki, N.2    Purfatholah, A.A.3    Najmabadi, H.4    Mortazavi, Y.5    Arzanian, M.T.6
  • 84
    • 0043028676 scopus 로고    scopus 로고
    • Clonality profile in relapsed precursor-B-ALL children by genescan and sequencing analyses. Consequences on minimal residual disease monitoring
    • PID: 12886245, COI: 1:CAS:528:DC%2BD3sXlslOitrg%3
    • Germano GD, Del Giudice L, Palatron S, Giarin E, Cazzaniga G, Biondi A, et al. Clonality profile in relapsed precursor-B-ALL children by genescan and sequencing analyses. Consequences on minimal residual disease monitoring. Leukemia. 2003;17(8):1573–82.
    • (2003) Leukemia , vol.17 , Issue.8 , pp. 1573-1582
    • Germano, G.D.1    Del Giudice, L.2    Palatron, S.3    Giarin, E.4    Cazzaniga, G.5    Biondi, A.6
  • 85
    • 84871525322 scopus 로고    scopus 로고
    • Deep-sequencing approach for minimal residual disease detection in acute lymphoblastic leukemia
    • PID: 23074282, COI: 1:CAS:528:DC%2BC3sXms1eksA%3D%3
    • Faham M, Zheng J, Moorhead M, Carlton VE, Stow P, Coustan-Smith E, et al. Deep-sequencing approach for minimal residual disease detection in acute lymphoblastic leukemia. Blood. 2012;120(26):5173–80.
    • (2012) Blood. , vol.120 , Issue.26 , pp. 5173-5180
    • Faham, M.1    Zheng, J.2    Moorhead, M.3    Carlton, V.E.4    Stow, P.5    Coustan-Smith, E.6
  • 86
    • 77954601328 scopus 로고    scopus 로고
    • Boyd SD, Marshall EL, Merker JD, Maniar JM, Zhang LN, Sahaf B, et al. Measurement and clinical monitoring of human lymphocyte clonality by massively parallel VDJ pyrosequencing. Sci Transl Med. 2009;1(12):12ra23.
    • Boyd SD, Marshall EL, Merker JD, Maniar JM, Zhang LN, Sahaf B, et al. Measurement and clinical monitoring of human lymphocyte clonality by massively parallel VDJ pyrosequencing. Sci Transl Med. 2009;1(12):12ra23.
  • 87
    • 0032870962 scopus 로고    scopus 로고
    • Clinically useful information provided by the flow cytometric immunophenotyping of hematological malignancies: current status and future directions
    • Orfao A, Schmitz G, Brando B, Ruiz-Arguelles A, Basso G, Braylan R, et al. Clinically useful information provided by the flow cytometric immunophenotyping of hematological malignancies: current status and future directions. Clin Chem. 1999;45(10):1709.
    • (1999) Clin Chem. , vol.45 , Issue.10 , pp. 1709
    • Orfao, A.1    Schmitz, G.2    Brando, B.3    Ruiz-Arguelles, A.4    Basso, G.5    Braylan, R.6


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