Quantification of minimal residual disease in children with oligoclonal B-precursor acute lymphoblastic leukemia indicates that the clones that grow out during relapse already have the slowest rate of reduction during induction therapy

Leukemia

Volumn 15, Issue 1, 2001, Pages 134-140

  De Haas, V ^a   Verhagen, O J H M ^a   Von Dem Borne, A E G Kr ^b   Kroes, W ^b   Van Den Berg, H ^a   Van Der Schoot, C E ^a,b  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

Acute lymphoblastic leukemia (ALL); Antigen receptor rearrangements; Clonal evolution; Minimal residual disease (MRD); Oligoclonality

Indexed keywords

ASPARAGINASE; CYTARABINE; DAUNORUBICIN; IMMUNOGLOBULIN HEAVY CHAIN; LYMPHOCYTE ANTIGEN RECEPTOR; METHOTREXATE; PREDNISOLONE; T LYMPHOCYTE RECEPTOR DELTA CHAIN; VINCRISTINE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ARTICLE; B CELL LEUKEMIA; BONE MARROW; CANCER RECURRENCE; CASE REPORT; CELL KINETICS; CHILD; DILUTION; GENE REARRANGEMENT; HUMAN; HYPOTHESIS; IMMUNOGLOBULIN GENE; LEUKEMIA REMISSION; LYMPHOCYTE CLONE; MALE; MINIMAL RESIDUAL DISEASE; POLYMERASE CHAIN REACTION; PRE B LYMPHOCYTE; PRIORITY JOURNAL; RECEPTOR GENE; T LYMPHOCYTE RECEPTOR GENE;

EID: 0035128917     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2401970     Document Type: Article

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