Effects of toluene, acrolein and vinyl chloride on motor activity of Drosophila melanogaster

Neurotoxicology and Teratology

Volumn 47, Issue , 2015, Pages 114-124

  Tatum Gibbs, K R ^a   McKee, J M ^b   Higuchi, M ^b   Bushnell, P J ^b  

^a OAK RIDGE INSTITUTE FOR SCIENCE AND EDUCATION   (United States)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Fruit fly; Narcosis; Sex difference; Toxicity screening; Volatile organic compounds

Indexed keywords

ACROLEIN; TOLUENE; VINYL CHLORIDE; AIR POLLUTANT; CARCINOGEN; VOLATILE ORGANIC COMPOUND;

ARTICLE; CONCENTRATION (PARAMETERS); DROSOPHILA MELANOGASTER; FEMALE; MALE; MOTOR ACTIVITY; NONHUMAN; POLLUTION TRANSPORT; SEX DIFFERENCE; TOXICITY TESTING; AIR POLLUTANT; ANALYSIS OF VARIANCE; ANIMAL; DOSE RESPONSE; DRUG EFFECTS; TIME; TOXICITY;

ACROLEIN; AIR POLLUTANTS; ANALYSIS OF VARIANCE; ANIMALS; CARCINOGENS; DOSE-RESPONSE RELATIONSHIP, DRUG; DROSOPHILA MELANOGASTER; FEMALE; MALE; MOTOR ACTIVITY; TIME FACTORS; TOLUENE; VINYL CHLORIDE; VOLATILE ORGANIC COMPOUNDS;

EID: 84919919309     PISSN: 08920362     EISSN: 18729738     Source Type: Journal    
DOI: 10.1016/j.ntt.2014.11.008     Document Type: Article

References (49)

1. (EPA), U.S.E.P.A. The U.S. Environmental Protection Agency's strategic plan for evaluating the toxicity of chemicals. The ORD future of toxicology working group 2009.
2. Al-Anzi B., Tracey W.D., Benzer S. Response of Drosophila to wasabi is mediated by painless, the fly homolog of mammalian TRPA1/ANKTM1. Curr Biol 2006, 16(10):1034-1040.
3. Anholt R.R., Lyman R.F., Mackay T.F. Effects of single P-element insertions on olfactory behavior in Drosophila melanogaster. Genetics 1996, 143(1):293-301.
4. Benignus V.A., Boyes W.K., Bushnell P.J. A dosimetric analysis of behavioral effects of acute toluene exposure in rats and humans. Toxicol Sci 1998, 43(2):186-195.
5. Brown E.B., Layne J.E., Zhu C., Jegga A.G., Rollmann S.M. Genome-wide association mapping of natural variation in odour-guided behaviour in Drosophila. Genes Brain Behav 2013, 12(5):503-515.
6. Bushnell P.J., Evans H.L., Palmes E.D. Effects of toluene inhalation on carbon dioxide production and locomotor activity in mice. Fundam Appl Toxicol 1985, 5(5):971-977.
7. Collins F.S., Gray G.M., Bucher J.R. Toxicology. Transforming environmental health protection. Science 2008, 319(5865):906-907.
8. Dix D.J., Kavlock R.J., Houck J., Martin M.T., Judson R. ToxCast (Retrieved 8 August, 2008, from). http://www.epa.gov/ncct/toxcast.
9. Fernandez M.P., Kravitz E.A. Aggression and courtship in Drosophila: pheromonal communication and sex recognition. J Comp Physiol A Neuroethol Sens Neural Behav Physiol 2013, 199(11):1065-1076.
10. Firestone M., Kavlock R., Zenick H., Kramer M., U.S.E.P.A.W.G.o.t.F.o.T.T. The U.S. Environmental Protection Agency strategic plan for evaluating the toxicity of chemicals. J Toxic Environ Health B 2010, 13(2-4):139-162.
11. Gaudry Q., Nagel K.I., Wilson R.I. Smelling on the fly: sensory cues and strategies for olfactory navigation in Drosophila. Curr Opin Neurobiol 2012, 22(2):216-222.
12. Harbison S.T., McCoy L.J., Mackay T.F. Genome-wide association study of sleep in Drosophila melanogaster. BMC Genomics 2013, 14:281.
13. Herrero P. Fruit fly behavior in response to chemosensory signals. Peptides 2012, 38(2):228-237.
14. Hinman D.J. Biphasic dose-response relationship for effects of toluene inhalation on locomotor activity. Pharmacol Biochem Behav 1987, 26(1):65-69.
15. Huang W., Richards S., Carbone M.A., Zhu D., Anholt R.R., Ayroles J.F., et al. Epistasis dominates the genetic architecture of Drosophila quantitative traits. Proc Natl Acad Sci U S A 2012, 109(39):15553-15559.
16. Huang W., Massouras A., Inoue Y., Peiffer J., Ramia M., Tarone A.M., et al. Natural variation in genome architecture among 205 Drosophila melanogaster genetic reference panel lines. Genome Res 2014, 24(7):1193-1208.
17. Huber R., Hill S.L., Holladay C., Biesiadecki M., Tononi G., Cirelli C. Sleep homeostasis in Drosophila melanogaster. Sleep 2004, 27(4):628-639.
18. Inamdar A.A., Hossain M.M., Bernstein A.I., Miller G.W., Richardson J.R., Bennett J.W. Fungal-derived semiochemical 1-octen-3-ol disrupts dopamine packaging and causes neurodegeneration. Proc Natl Acad Sci U S A 2013, 110(48):19561-19566.
19. Inamdar A.A., Zaman T., Morath S.U., Pu D.C., Bennett J.W. Drosophila melanogaster as a model to characterize fungal volatile organic compounds. Environ Toxicol 2014, 29(7):829-836.
20. Jordan K.W., Craver K.L., Magwire M.M., Cubilla C.E., Mackay T.F., Anholt R.R. Genome-wide association for sensitivity to chronic oxidative stress in Drosophila melanogaster. PLoS ONE 2012, 7(6):e38722.
21. Judson R., Richard A., Dix D.J., Houck K., Martin M., Kavlock R., et al. The toxicity data landscape for environmental chemicals. Environ Health Perspect 2008, 117(5).
22. Judson R.S., Houck K.A., Kavlock R.J., Knudsen T.B., Martin M.T., Mortensen H.M., et al. In vitro screening of environmental chemicals for targeted testing prioritization: the ToxCast project. Environ Health Perspect 2009, 118(4).
23. Kang K., Pulver S.R., Panzano V.C., Chang E.C., Griffith L.C., Theobald D.L., et al. Analysis of Drosophila TRPA1 reveals an ancient origin for human chemical nociception. Nature 2010, 464(7288):597-600.
24. Kavlock R., Chandler K., Houck K., Hunter S., Judson R., Kleinstreuer N., et al. Update on EPA's ToxCast program: providing high throughput decision support tools for chemical risk management. Chem Res Toxicol 2012, 25(7):1287-1302.
25. Mackay T.F.C., Richards S., Stone E.A., Barbadilla A., Ayroles J.F., Zhu D., et al. The Drosophila melanogaster genetic reference panel. Nature 2012, 482(7384):173-178.
26. Moore M.S., DeZazzo J., Luk A.Y., Tully T., Singh C.M., Heberlein U. Ethanol intoxication in Drosophila: genetic and pharmacological evidence for regulation by the cAMP signaling pathway. Cell 1998, 93(6):997-1007.
27. Morozova T.V., Mackay T.F., Anholt R.R. Transcriptional networks for alcohol sensitivity in Drosophila melanogaster. Genetics 2011, 187(4):1193-1205.
28. Morozova T.V., Mackay T.F., Anholt R.R. Genetics and genomics of alcohol sensitivity. Mol Genet Genomics 2014, 289(3):253-269.
29. NRC Toxicity testing in the 21st century: a vision and a strategy 2007, National Academies Press, Washington D.C.
30. Parr J., Large A., Wang X., Fowler S.C., Ratzlaff K.L., Ruden D.M. The inebri-actometer: a device for measuring the locomotor activity of Drosophila exposed to ethanol vapor. J Neurosci Methods 2001, 107(1-2):93-99.
31. Rieger D., Fraunholz C., Popp J., Bichler D., Dittmann R., Helfrich-Forster C. The fruit fly Drosophila melanogaster favors dim light and times its activity peaks to early dawn and late dusk. J Biol Rhythms 2007, 22(5):387-399.
32. Sambandan D., Yamamoto A., Fanara J.J., Mackay T.F., Anholt R.R. Dynamic genetic interactions determine odor-guided behavior in Drosophila melanogaster. Genetics 2006, 174(3):1349-1363.
33. Scholz H. Intoxicated fly brains: neurons mediating ethanol-induced behaviors. J Neurogenet 2009, 23(1-2):111-119.
34. Shukla S.J., Huang R., Austin C.P., Xia M. The future of toxicity testing: a focus on in vitro methods using a quantitative high-throughput screening platform. Drug Discov Today 2010, 15(23-24):997-1007.
35. Singh C.M., Heberlein U. Genetic control of acute ethanol-induced behaviors in Drosophila. Alcohol Clin Exp Res 2000, 24(8):1127-1136.
36. Swarup S., Huang W., Mackay T.F., Anholt R.R. Analysis of natural variation reveals neurogenetic networks for Drosophila olfactory behavior. Proc Natl Acad Sci U S A 2013, 110(3):1017-1022.
37. Tegeris J.S., Balster R.L. A comparison of the acute behavioral effects of alkylbenzenes using a functional observational battery in mice. Fundam Appl Toxicol 1994, 22(2):240-250.
38. Tice R.R., Austin C.P., Kavlock R.J., Bucher J.R. Improving the human hazard characterization of chemicals: a Tox21 update. Environ Health Perspect 2013, 121(7):756-765.
39. Tunstall N.E., Warr C.G. Chemical communication in insects: the peripheral odour coding system of Drosophila melanogaster. Adv Exp Med Biol 2012, 739:59-77.
40. U.S. Environmental Protection Agency, E Toxicological review of acrolein 2003, Government Printing Office, Washington, DC.
41. U.S. Environmental Protection Agency, E. Toxicological review of vinyl chloride 2000, Government Printing Office, Washington, DC.
42. U.S. Environmental Protection Agency, E. Toxicological review of toluene (CAS no. 108-88-3). Support of summary information on the Integrated Risk Information System (IRIS) 2005, US Government Printing Office, Washington, DC.
43. Vet L.E.M., Van Lenteren J.C., Heymans M., Meelis E. An airflow olfactometer for measuring olfactory responses of hymenopterous parasitoids and other small insects. Physiol Entomol 1983, 8:97-106.
44. Vosshall L.B., Stocker R.F. Molecular architecture of smell and taste in Drosophila. Annu Rev Neurosci 2007, 30:505-533.
45. Wasserkort R., Koller T. Screening toxic effects of volatile organic compounds using Drosophila melanogaster. J Appl Toxicol 1997, 17(2):119-125.
46. Weber A.L., Khan G.F., Magwire M.M., Tabor C.L., Mackay T.F., Anholt R.R. Genome-wide association analysis of oxidative stress resistance in Drosophila melanogaster. PLoS ONE 2012, 7(4):e34745.
47. Wolf F.W., Rodan A.R., Tsai L.T., Heberlein U. High-resolution analysis of ethanol-induced locomotor stimulation in Drosophila. J Neurosci 2002, 22(24):11035-11044.
48. Wood R.W., Colotla V.A. Biphasic changes in mouse motor activity during exposure to toluene. Fundam Appl Toxicol 1990, 14(1):6-14.
49. Zhou S., Campbell T.G., Stone E.A., Mackay T.F., Anholt R.R. Phenotypic plasticity of the Drosophila transcriptome. PLoS Genet 2012, 8(3):e1002593.