Estradiol regulation of hypothalamic astrocyte adenosine 5'-monophosphate-activated protein kinase activity: Role of hindbrain catecholamine signaling

Brain Research Bulletin

Volumn 110, Issue , 2015, Pages 47-53

  Tamrakar, Pratistha ^a   Briski, Karen P ^a  

^a UNIVERSITY OF LOUISIANA AT MONROE   (United States)

Author keywords

6 OHDA; Astrocyte; Insulin induced hypoglycemia; Laser catapult microdissection; PhosphoAMPK; Ventromedial hypothalamic nucleus

Indexed keywords

CATECHOLAMINE; ESTRADIOL; GLIAL FIBRILLARY ACIDIC PROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; NEUROTOXIN; OXIDOPAMINE; ADRENERGIC RECEPTOR STIMULATING AGENT; ANTIDIABETIC AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY LABELING; ARCUATE NUCLEUS; ARTICLE; ASTROCYTE; BRAIN FOURTH VENTRICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; HORMONAL REGULATION; HYPOTHALAMIC PARAVENTRICULAR NUCLEUS; HYPOTHALAMUS; HYPOTHALAMUS VENTROMEDIAL NUCLEUS; IMMUNOCYTOCHEMISTRY; INSULIN HYPOGLYCEMIA; LATERAL HYPOTHALAMUS; NONHUMAN; PARAVENTRICULAR THALAMIC NUCLEUS; PROTEIN EXPRESSION; RAT; RHOMBENCEPHALON; WESTERN BLOTTING; ANIMAL; DRUG EFFECTS; ENZYMOLOGY; HYPOGLYCEMIA; METABOLISM; OVARIECTOMY; PHOSPHORYLATION; SPRAGUE DAWLEY RAT;

ADRENERGIC AGENTS; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; ASTROCYTES; CATECHOLAMINES; ESTRADIOL; FEMALE; GLIAL FIBRILLARY ACIDIC PROTEIN; HYPOGLYCEMIA; HYPOGLYCEMIC AGENTS; HYPOTHALAMUS; INSULIN; OVARIECTOMY; OXIDOPAMINE; PHOSPHORYLATION; RATS, SPRAGUE-DAWLEY; RHOMBENCEPHALON;

EID: 84919782917     PISSN: 03619230     EISSN: 18732747     Source Type: Journal    
DOI: 10.1016/j.brainresbull.2014.12.002     Document Type: Article

References (31)

1. Alquier T., Kawashima J., Tsuji Y., Kahn B.B. Role of hypothalamic adenosine 5'-monophosphate-activated protein kinase in the impaired counterregulatory response induced by repetitive neuroglucopenia. Endocrinology 2007, 148:1367-1375.
2. Bellin S.I., Ritter S. Insulin-induced elevation of hypothalamic norepinephrine turnover persists after glucorestoration unless feeding occurs. Brain Res. 1981, 217:327-337.
3. Beverly J.L., De Vries M.G., Bouman S.D., Arseneau L.M. Noradrenergic and GABAergic systems in the medial hypothalamus are activated during hypoglycemia. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2001, 280:R563-R569.
4. Briski K.P., Marshall E.S., Sylvester P.W. Effects of estradiol on glucoprivic transactivation of catecholaminergic neurons in the female rat caudal brainstem. Neuroendocrinology 2001, 73:369-377.
5. Butcher R.L., Collins W.E., Fugo N.W. Plasma concentrations of LH, FSH, progesterone, and estradiol-17beta throughout the 4-day estrous cycle of the rat. Endocrinology 1974, 94:1704-1708.
6. Cherian A., Briski K.P. Estradiol regulates phosphoAMPK, glucokinase, substrate transporter, and dopamine-beta-hydroxylase adaptation to repeated insulin-induced hypoglycemia in female rat A2 noradrenergic neurons. J. Neurosci. Res. 2012, 90:1347-1358.
7. Claret M., Smith M.A., Batterham R.L., Selman C., Choudhury A.I., Fryer L.G., Clements M., Al-Qassab H., Heffron H., Xu A.W., Speakman J.R., Barsh G.S., Viollet B., Vaulont S., Ashford M.L., Carling D., Withers D.J. AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons. J. Clin. Invest. 2007, 117:2325-2336.
8. Dong J.H., Chen X., Cui M., Yu X., Pang Q., Sun J.P. β2-Adrenergic receptor and astrocyte glucose metabolism. J. Mol. Neurosci. 2012, 48:456-463.
9. Fillenz M., Lowry J.P., Boutelle M.G., Fray A.E. The role of astrocytes and noradrenaline in neuronal glucose metabolism. Acta Physiol. Scand. 1999, 167:275-284.
10. Fuente-Martin E., Garcia-Caceres C., Morselli E., Clegg D.J., Chowen J.A., Finan B., Brinton R.D., Tschöp M.H. Estrogen, astrocytes and the neuroendocrine control of metabolism. Rev. Endocr. Metab. Disord. 2013, 14:331-338.
11. Gabryel B., Kost A., Kasprowska D., Liber S., Machnik G., Wiaderkiewicz R., Labuzek K. AMP-activated protein kinase is involved in induction of protective autophagy in astrocytes exposed to oxygen-glucose deprivation. Cell Biol. Int. 2014, 10.1002/cbin.10299.
12. Goodman R.L. A quantitative analysis of the physiological role of estradiol and progesterone in the control of tonic and surge secretion of luteinizing hormone in the rat. Endocrinology 1978, 102:142-150.
13. Gujar A.D., Ibrahim B.A., Tamrakar P., Koshy Cherian A., Briski K.P. Hindbrain lactostasis regulates hypothalamic AMPK activity and hypothalamic metabolic neurotransmitter mRNA and protein responses to hypoglycemia. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2014, 306:R457-R469.
14. Han S.M., Namkoong C., Jang P.G., Park I.S., Hong S.W., Katakami H., Chun S., Kim S.W., Park J.Y., Lee K.U., Kim M.S. Hypothalamic AMP-activated protein kinase mediates counter-regulatory responses to hypoglycaemia in rats. Diabetologia 2005, 48:2170-2178.
15. 2+]. Neurochem. Int. 2010, 57:411-420.
16. Iwabuchi S., Kawahara K., Harata N.C. Effects of pharmacological inhibition of AMP-activated protein kinase on GLUT3 expression and the development of ischemic tolerance in astrocytes. Neurosci. Res. 2014, pii:S0168-0102(14)00072-8. 10.1016/j.neures.2014.04.007.
17. Kale A.Y., Paranjape S.A., Briski K.P. I.C.V. administration of the nonsteroidal glucocorticoid receptor antagonist, CP 4-72555, prevents exacerbated hypoglycemia during repeated insulin administration. Neuroscience 2006, 140:555-565.
18. Kuo J., Hariri O.R., Bondar G., Ogi J., Micevych P. Membrane estrogen receptor-alpha interacts with metabotropic glutamate receptor type 1a to mobilize intracellular calcium in hypothalamic astrocytes. Endocrinology 2009, 150:1369-1376.
19. Mountjoy P.D., Bailey S.J., Rutter G.A. Inhibition by glucose or leptin of hypothalamic neurons expressing neuropeptide Y requires changes in AMP-activated protein kinase activity. Diabetologia 2007, 50:168-177.
20. Murphy B.A., Fioramonti X., Jochnowitz N., Fakira K., Gagen K., Contie S., Lorsignol A., Penicaud L., Martin W.J., Routh V.H. Fasting enhances the response of arcuate neuropeptide Y glucose-inhibited neurons to decreased extracellular glucose. Am. J. Physiol. Cell Physiol. 2009, 296:C746-C756.
21. Magistretti P.J., Sorg O., Yu N., Martin J.L., Pellerin L. Neurotransmitters regulate energy metabolism in astrocytes: implications for the metabolic trafficking between neural cells. Dev. Neurosci. 1993, 15:306-312.
22. Martínez de Morentin P.B., González-García I., Martins L., Lage R., Fernández-Mallo D., Martínez-Sánchez N., Ruíz-Pino F., Liu J., Morgan D.A., Pinilla L., Gallego R., Saha A.K., Kalsbeek A., Fliers E., Bisschop P.H., Diéguez C., Nogueiras R., Rahmouni K., Tena-Sempere M., López M. Estradiol regulates brown adipose tissue thermogenesis via hypothalamic AMPK. Cell Metab. 2014, 20:41-53.
23. Micevych P.E., Chaban V., Ogi J., Dewing P., Lu J.K., Sinchak K. Estradiol stimulation progesterone synthesis in hypothalamic astrocyte cultures. Endocrinology 2007, 148:782-789.
24. Nedungadi T.P., Goleman W.L., Paranjape S.A., Kale A.Y., Briski K.P. Effects of estradiol on glycemic and CNS neuronal activational responses to recurrent insulin-induced hypoglycemia in the ovariectomized female rat. Neuroendocrinology 2006, 84:235-243.
25. Oomura Y. Glucose as a regulator of neuronal activity. Adv. Metab. Disord. 1983, 10:31-65.
26. Oomura Y., Yoshimatsu H. Neural network of glucose monitoring system. J. Auton. Nerv. Syst. 1984, 10:359-372.
27. Paranpape S.A., Briski K.P. Recurrent insulin-induced hypoglycemia causes site-specific patterns of habituation or amplification of CNS neuronal genomic activation. Neuroscience 2005, 130:957-970.
28. Pellerin L., Magistretti P.J. Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization. Proc. Natl. Acad. Sci. 1994, 91:10625-10629.
29. Selvage D.J., Lee S.Y., Parsons L.H., Seo D.O., Rivier C.L. A hypothalamic-testicular neural pathway is influenced by brain catecholamines, but not testicular blood flow. Endocrinology 2004, 145:1750-1759.
30. Stobart J.L., Anderson C.M. Role of astrocytes as gatekeepers of neuronal energy supply. Front. Cell. Neurosci. 2013, 7:1-21.
31. Tamrakar P., Shrestha P., Briski K.P. Sex-specific basal and hypoglycemic patterns of in vivo caudal dorsal vagal complex astrocyte glycogen metabolic enzyme protein expression. Brain Res. 2014, 10.1016/j.brainres.2014.08.042.