The antipsoriatic agent monomethylfumarate has antiproliferative, prodifferentiative, and anti-inflammatory effects on keratinocytes

Journal of Pharmacology and Experimental Therapeutics

Volumn 352, Issue 1, 2015, Pages 90-97

  Helwa, Inas ^a,b,c   Patel, Ravi ^c   Karempelis, Peter ^c   Kaddour Djebbar, Ismail ^a,c   Choudhary, Vivek ^a,c   Bollag, Wendy B ^a,b,c  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b AUGUSTA UNIVERSITY   (United States)

^c MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIPSORIASIS AGENT; CYTOKERATIN 10; CYTOKINE; DNA; FUMARIC ACID METHYL ESTER; INTERLEUKIN 1ALPHA; INTERLEUKIN 6; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; TRITIUM; TUMOR NECROSIS FACTOR ALPHA; ANTIINFLAMMATORY AGENT; CITRACONIC ACID; FUMARIC ACID DERIVATIVE; MALEIC ACID DERIVATIVE; MESSENGER RNA;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA SYNTHESIS; DRUG ACTIVITY; DRUG TARGETING; ENZYME ACTIVITY; HUMAN; HUMAN CELL; KERATINOCYTE; NONHUMAN; PRODIFFERENTIATIVE EFFECT; PROTEIN EXPRESSION; PSORIASIS; ANIMAL; BIOSYNTHESIS; CYTOLOGY; DOSE RESPONSE; DRUG EFFECTS; ENDOTHELIUM CELL; FEMALE; GENE EXPRESSION REGULATION; GENETICS; MALE; METABOLISM; MOUSE; PATHOLOGY; SECRETION (PROCESS);

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL DIFFERENTIATION; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; FEMALE; FUMARATES; GENE EXPRESSION REGULATION; KERATINOCYTES; MALE; MALEATES; MICE; PSORIASIS; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84919775660     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.114.218818     Document Type: Article

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