Monomethylfumarate reduces in vitro migration of mononuclear cells

Neurological Sciences

Volumn 35, Issue 7, 2014, Pages 1121-1125

  Dehmel, T ^a   Dobert M ^a   Pankratz, S ^b   Leussink, V I ^a   Hartung, H P ^a   Wiendl, H ^b   Kieseier, B C ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

Blood brain barrier; Chemokines; Diemethylfumarate; Fumaric acid; Matrix metalloproteinases; Mode of action; Multiple sclerosis; Therapy

Indexed keywords

ALPHA4 INTEGRIN; BETA1 INTEGRIN; CHEMOKINE RECEPTOR CCR5; FUMARIC ACID METHYL ESTER; GLUTAMATE CYSTEINE LIGASE; HEME OXYGENASE 1; MATRIX METALLOPROTEINASE; NADPH OXIDOREDUCTASE 1; OXIDOREDUCTASE; UNCLASSIFIED DRUG; CITRACONIC ACID; FUMARIC ACID DERIVATIVE; LEUKOCYTE ANTIGEN; MALEIC ACID DERIVATIVE; NFE2L2 PROTEIN, HUMAN; NQO1 PROTEIN, HUMAN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); TRANSCRIPTION FACTOR NRF2;

ADULT; ARTICLE; CELL MIGRATION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; LYMPHOCYTE; MACROPHAGE; MALE; MULTIPLE SCLEROSIS; OXIDATIVE STRESS; PERIPHERAL BLOOD MONONUCLEAR CELL; T LYMPHOCYTE; BLOOD; CELL MOTION; DRUG EFFECTS; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MONONUCLEAR CELL; NONPARAMETRIC TEST; PHYSIOLOGY; SIGNAL TRANSDUCTION; TIME;

ADULT; ANTIGENS, CD; CELL MOVEMENT; FEMALE; FLOW CYTOMETRY; FUMARATES; GENE EXPRESSION REGULATION; GLUTAMATE-CYSTEINE LIGASE; HEME OXYGENASE-1; HUMANS; LEUKOCYTES, MONONUCLEAR; MALE; MALEATES; MULTIPLE SCLEROSIS; NAD(P)H DEHYDROGENASE (QUINONE); NF-E2-RELATED FACTOR 2; SIGNAL TRANSDUCTION; STATISTICS, NONPARAMETRIC; TIME FACTORS;

EID: 84903373727     PISSN: 15901874     EISSN: 15903478     Source Type: Journal    
DOI: 10.1007/s10072-014-1663-2     Document Type: Article

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