Knockdown of ANLN by lentivirus inhibits cell growth and migration in human breast cancer

Molecular and Cellular Biochemistry

Volumn 398, Issue 1-2, 2015, Pages 11-19

  Zhou, Weibing ^a   Wang, Zhan ^a   Shen, Ni ^a   Pi, Weiwei ^a   Jiang, Wuzhong ^a   Huang, Juan ^a   Hu, Yuanping ^a   Li, Xiong ^a   Sun, Lunquan ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Anillin; Breast cancer; Immunohistochemistry; Proliferation; RNA interference

Indexed keywords

ACTIN BINDING PROTEIN; CYCLIN D1; CYCLIN DEPENDENT KINASE 1; PROTEIN ANILLIN; UNCLASSIFIED DRUG; ACTIN-BINDING PROTEIN ANILLIN, HUMAN;

ARTICLE; BREAST CANCER; CANCER INHIBITION; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE PROGRESSION; CELL PROLIFERATION; COLONY FORMATION; CONTROLLED STUDY; DOWN REGULATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LENTIVIRINAE; MAJOR CLINICAL STUDY; MIGRATION INHIBITION; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RNA INTERFERENCE; BREAST TUMOR; CELL CYCLE; CELL MOTION; DRUG SCREENING; FEMALE; FLUORESCENCE MICROSCOPY; GENE EXPRESSION REGULATION; GENETICS; HEK293 CELL LINE; METABOLISM; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL LINE; WESTERN BLOTTING;

LENTIVIRUS;

BLOTTING, WESTERN; BREAST NEOPLASMS; CELL CYCLE; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HEK293 CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; LENTIVIRUS; MICROFILAMENT PROTEINS; MICROSCOPY, FLUORESCENCE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TUMOR STEM CELL ASSAY;

EID: 84919773167     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-014-2200-6     Document Type: Article

References (27)

1. Field CM, Alberts BM (1995) Anillin, a contractile ring protein that cycles from the nucleus to the cell cortex. J Cell Biol 131:165–178
2. Zhang L, Maddox AS (2010) Anillin. Curr Biol 20:R135–R136. doi:10.1016/j.cub.2009.12.017
3. Piekny AJ, Maddox AS (2010) The myriad roles of Anillin during cytokinesis. Semin Cell Dev Biol 21:881–891. doi:10.1016/j.semcdb.2010.08.002
4. Hickson GR, O’Farrell PH (2008) Anillin: a pivotal organizer of the cytokinetic machinery. Biochem Soc Trans 36:439–441. doi:10.1042/BST0360439
5. Sisson JC, Field C, Ventura R, Royou A, Sullivan W (2000) Lava lamp, a novel peripheral golgi protein, is required for Drosophila melanogaster cellularization. J Cell Biol 151:905–918
6. Straight AF, Field CM, Mitchison TJ (2005) Anillin binds nonmuscle myosin II and regulates the contractile ring. Mol Biol Cell 16:193–201. doi:10.1091/mbc.E04-08-0758
7. Oegema K, Savoian MS, Mitchison TJ, Field CM (2000) Functional analysis of a human homologue of the Drosophila actin binding protein anillin suggests a role in cytokinesis. J Cell Biol 150:539–552
8. Kinoshita M, Field CM, Coughlin ML, Straight AF, Mitchison TJ (2002) Self- and actin-templated assembly of Mammalian septins. Dev Cell 3:791–802
9. Piekny AJ, Glotzer M (2008) Anillin is a scaffold protein that links RhoA, actin, and myosin during cytokinesis. Curr Biol 18:30–36. doi:10.1016/j.cub.2007.11.068
10. D’Avino PP, Takeda T, Capalbo L, Zhang W, Lilley KS, Laue ED, Glover DM (2008) Interaction between anillin and RacGAP50C connects the actomyosin contractile ring with spindle microtubules at the cell division site. J Cell Sci 121:1151–1158. doi:10.1242/jcs.026716
11. Gregory SL, Ebrahimi S, Milverton J, Jones WM, Bejsovec A, Saint R (2008) Cell division requires a direct link between microtubule-bound RacGAP and anillin in the contractile ring. Curr Biol 18:25–29. doi:10.1016/j.cub.2007.11.050
12. Hall PA, Todd CB, Hyland PL, McDade SS, Grabsch H, Dattani M, Hillan KJ, Russell SE (2005) The septin-binding protein anillin is overexpressed in diverse human tumors. Clin Cancer Res 11:6780–6786. doi:10.1158/1078-0432.ccr-05-0997
13. Olakowski M, Tyszkiewicz T, Jarzab M, Krol R, Oczko-Wojciechowska M, Kowalska M, Kowal M, Gala GM, Kajor M, Lange D, Chmielik E, Gubala E, Lampe P, Jarzab B (2009) NBL1 and anillin (ANLN) genes over-expression in pancreatic carcinoma. Folia Histochem Cytobiol 47:249–255. doi:10.2478/v10042-009-0031-1
14. Suzuki C, Daigo Y, Ishikawa N, Kato T, Hayama S, Ito T, Tsuchiya E, Nakamura Y (2005) ANLN plays a critical role in human lung carcinogenesis through the activation of RHOA and by involvement in the phosphoinositide 3-kinase/AKT pathway. Cancer Res 65:11314–11325. doi:10.1158/0008-5472.CAN-05-1507
15. den Hollander P, Savage MI, Brown PH (2013) Targeted Therapy for Breast Cancer Prevention. Front Oncol 3:250. doi:10.3389/fonc.2013.00250
16. Labrie F (2007) Drug insight: breast cancer prevention and tissue-targeted hormone replacement therapy. Nat Clin Pract Endocrinol Metab 3:584–593. doi:10.1038/ncpendmet0559
17. Pc OL, Penny SA, Dolan RT, Kelly CM, Madden SF, Rexhepaj E, Brennan DJ, McCann AH, Ponten F, Uhlen M, Zagozdzon R, Duffy MJ, Kell MR, Jirstrom K, Gallagher WM (2013) Systematic antibody generation and validation via tissue microarray technology leading to identification of a novel protein prognostic panel in breast cancer. BMC Cancer 13:175. doi:10.1186/1471-2407-13-175
18. Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D (2011) Global cancer statistics. CA Cancer J Clin 61:69–90. doi:10.3322/caac.20107
19. Bartosch B, Cosset FL (2004) Strategies for retargeted gene delivery using vectors derived from lentiviruses. Curr Gene Ther 4:427–443
20. Emeagi PU, Goyvaerts C, Maenhout S, Pen J, Thielemans K, Breckpot K (2013) Lentiviral vectors: a versatile tool to fight cancer. Curr Mol Med 13:602–625
21. Shimizu S, Seki N, Sugimoto T, Horiguchi S, Tanzawa H, Hanazawa T, Okamoto Y (2007) Identification of molecular targets in head and neck squamous cell carcinomas based on genome-wide gene expression profiling. Oncol Rep 18:1489–1497
22. Skrzypski M, Jassem E, Taron M, Sanchez JJ, Mendez P, Rzyman W, Gulida G, Raz D, Jablons D, Provencio M, Massuti B, Chaib I, Perez-Roca L, Jassem J, Rosell R (2008) Three-gene expression signature predicts survival in early-stage squamous cell carcinoma of the lung. Clin Cancer Res 14:4794–4799. doi:10.1158/1078-0432.CCR-08-0576
23. Ronkainen H, Hirvikoski P, Kauppila S, Vaarala MH (2011) Anillin expression is a marker of favourable prognosis in patients with renal cell carcinoma. Oncol Rep 25:129–133
24. Kim H, Kim K, Yu SJ, Jang ES, Yu J, Cho G, Yoon JH, Kim Y (2013) Development of biomarkers for screening hepatocellular carcinoma using global data mining and multiple reaction monitoring. PLoS ONE 8:e63468. doi:10.1371/journal.pone.0063468
25. Hong J, Liu Z, Zhu H, Zhang X, Liang Y, Yao S, Wang F, Xie X, Zhang B, Tan T, Fu L, Nie J, Cheng C (2014) The tumor suppressive role of NUMB isoform 1 in esophageal squamous cell carcinoma. Oncotarget 5:5602–5614
26. Dong Y, Sui L, Sugimoto K, Tai Y, Tokuda M (2001) Cyclin D1-CDK4 complex, a possible critical factor for cell proliferation and prognosis in laryngeal squamous cell carcinomas. Int J Cancer 95:209–215
27. Zhong Z, Yeow WS, Zou C, Wassell R, Wang C, Pestell RG, Quong JN, Quong AA (2010) Cyclin D1/cyclin-dependent kinase 4 interacts with filamin A and affects the migration and invasion potential of breast cancer cells. Cancer Res 70:2105–2114. doi:10.1158/0008-5472.CAN-08-1108