Identification of molecular targets in head and neck squamous cell carcinomas based on genome-wide gene expression profiling

Oncology Reports

Volumn 18, Issue 6, 2007, Pages 1489-1497

  Shimizu, Satoya ^a   Seki, Naohiko ^a   Sugimoto, Takashi ^a   Horiguchi, Shigetoshi ^a   Tanzawa, Hideki ^a   Hanazawa, Toyoyuki ^a   Okamoto, Yoshitaka ^a  

^a CHIBA UNIVERSITY   (Japan)

Author keywords

7p14; Activin A; ANLN; Comparative genomic hybridization; Head and neck squamous cell carcinoma; Inhibin A; Microarray

Indexed keywords

DNA; MESSENGER RNA; RNA;

ARTICLE; CHROMOSOME 7; CHROMOSOME MAP; GENE EXPRESSION PROFILING; GENETICS; GENOME; HEAD AND NECK TUMOR; HUMAN; MIDDLE AGED; PATHOLOGY; SQUAMOUS CELL CARCINOMA;

CARCINOMA, SQUAMOUS CELL; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 7; DNA, NEOPLASM; GENE EXPRESSION PROFILING; GENOME, HUMAN; HEAD AND NECK NEOPLASMS; HUMANS; MIDDLE AGED; RNA, MESSENGER; RNA, NEOPLASM;

EID: 38449105399     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.18.6.1489     Document Type: Article

References (19)

1. Choi P and Chen C: Genetic expression profiles and biologic pathway alterations in head and neck squamous cell carcinoma. Cancer 104: 1113-1128, 2005. (Pubitemid 41278946)
2. Speicher MR, Howe C, Crotty P, du-Manoir S, Costa J and Ward DC: Comparative genomic hybridization detects novel deletions and amplifications in head and neck squamous cell carcinomas. Cancer Res 55: 1010-1013, 1995.
3. Bockmuhl U, Schluns K, Schmidt S, Matthias S and Petersen I: Chromosomal alterations during metastasis formation of head and neck squamous cell carcinoma. Gene Chromosomes Cancer 33: 29-35, 2002.
4. Halvorsen OJ, Oyan AM, Bo TH, Olsen S, Rostad K, Haukaas SA, Bakke AM, Marzolf B, Dimitrov K, Stordrange L, Lin B, Jonassen I, Hood L, Akslen LA and Kalland KH: Gene expression profiles in prostate cancer: association with patient subgroups and tumour differentiation. Int J Oncol 26: 329-336, 2005.
5. Nishidate T, Katagiri T, Lin ML, Mano Y, Miki Y, Kasumi F, Yoshimoto M, Tsunoda T, Hirata K and Nakamura Y: Genome-wide gene-expression profiles of breast-cancer cells purified with laser microbeam microdissection: identification of genes associated with progression and metastasis. Int J Oncol 25: 797-819, 2004.
6. Inoue Y, Shirane M, Miki C, Hiro J, Tanaka K, Kobayashi M, Mori K, Yanagi H and Kusunoki M: Gene expression profiles of colorectal carcinoma in neo-adjuvant chemotherapy. Int J Oncol 25: 1641-1649, 2004.
7. Reissmann PT, Koga H, Figlin RA, Holmes EC and Slamon DJ: Amplification and overexpression of the cyclin D1 and epidermal growth factor receptor genes in non-small-cell lung cancer. J Cancer Res Clin Oncol 125: 61-70, 1999. (Pubitemid 29161456)
8. Hashimoto Y, Oga A, Okami K, Imate Y, Yamashita Y and Sasaki K: Relationship between cytogenetic aberrations by CGH coupled with tissue microdissection and DNA ploidy by laser scanning cytometry in head and neck squamous cell carcinoma. Cytometry 40: 161-66, 2000. (Pubitemid 30322379)
9. Myllykangas S, Himberg J, Bohling T, Nagy B, Hollmen J and Knuutila S: DNA copy number amplification profiling of human neoplasms. Oncogene 25: 7324-7332, 2006. (Pubitemid 44809098)
10. Liehr T, Ries J, Wolff E, Fiedler W, Dahse R, Ernst G, Steininger H, Koscielny S, Girod S and Gebhart E: Gain of DNA copy number on chromosomes 3q26-qter and 5p14-pter is a frequent finding in head and neck squamous cell carcinomas. Int J Mol Med 2: 173-179, 1998.
11. Gebhart E, Ries J, Wiltfang J, Liehr T and Efferth T: Genomic gain of the epidermal growth factor receptor harboring band 7p12 is part of a complex pattern of genomic imbalances in oral squamous cell carcinomas. Arch Med Res 35: 385-394, 2004. (Pubitemid 40018178)
12. Zhang Y, Musci T and Derynck R: The tumor suppressor Smad4/DPC4 as a central mediator of Smad function. Curr Biol 7: 270-276, 1997. (Pubitemid 27176853)
13. Kleeff J, Ishiwata T, Friess H, Buchler MW and Korc M: Concomitant over-expression of activin/inhibin beta subunits and their receptors in human pancreatic cancer. Int J Cancer 77: 860-868, 1998. (Pubitemid 28378134)
14. Thomas TZ, Wang H, Niclasen P, O'Bryan MK, Evans LW, Groome NP, Pedersen J and Risbridger GP: Expression and localization of activin subunits and follistatins in tissues from men with high grade prostate cancer. J Clin Endocrinol Metab 82: 3851-3858, 1997. (Pubitemid 27509382)
15. Zheng W, Luo MP, Welt C, Lambert-Messerlian G, Sung CJ, Zhang Z, Ying SY, Schneyer AL, Lauchlan SC and Felix JC: Imbalanced expression of inhibin and activin subunits in primary epithelial ovarian cancer. Gynecol Oncol 69: 23-31, 1998. (Pubitemid 28201667)
16. Petraglia F, Florio P, Luisi S, Gallo R, Gadducci A, Vigano P, Di Blasio AM, Genazzani AR and Vale W: Expression and secretion of inhibin and activin in normal and neoplastic uterine tissues. High levels of serum activin A in women with endometrial and cervical carcinoma. J Clin Endocrinol Metab 83: 1194-1200, 1998. (Pubitemid 28496392)
17. Wildi S, Kleeff J, Maruyama H, Maurer CA, Buchler MW and Korc M: Overexpression of activin A in stage IV colorectal cancer. Gut 49: 409-417, 2001. (Pubitemid 32802577)
18. Poulaki V, Mitsiades N, Kruse FE, Radetzky S, Iliaki E, Kirchhof B and Joussen AM: Activin a in the regulation of corneal neovascularization and vascular endothelial growth factor expression. Am J Pathol 164: 1293-1302, 2004. (Pubitemid 38387795)
19. Kyzas PA, Stefanou D, Batistatou A and Agnantis NJ: Prognostic significance of VEGF immunohistochemical expression and tumor angiogenesis in head and neck squamous cell carcinoma. J Cancer Res Clin Oncol 131: 624-630, 2005. (Pubitemid 41558557)