Pet ownership is associated with increased risk of non-atopic asthma and reduced risk of atopy in childhood: Findings from a UK birth cohort

Clinical and Experimental Allergy

Volumn 45, Issue 1, 2015, Pages 200-210

  Collin, S M ^a   Granell, R ^a   Westgarth, C ^b   Murray, J ^a   Paul, E ^a   Sterne, J A C ^a   John Henderson, A ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

ALSPAC birth cohort; Asthma; Atopy; Pets

Indexed keywords

HOUSE DUST ALLERGEN;

ALLERGIC ASTHMA; ARTICLE; ASTHMA; CAT; CHILD; CHILDHOOD; CONTACT SENSITIZATION; CONTROLLED STUDY; DERMATOPHAGOIDES; DISEASE PREDISPOSITION; GRASS; HUMAN; MAJOR CLINICAL STUDY; NON ATOPIC ASTHMA; OUTCOME ASSESSMENT; PET ANIMAL; PRENATAL EXPOSURE; PRICK TEST; PRIORITY JOURNAL; RABBIT; RODENT; SCHOOL CHILD; UNITED KINGDOM; ADULT; AGE; ANIMAL; CLINICAL TRIAL; FEMALE; FOLLOW UP; GREAT BRITAIN; INFANT; MALE; MATERNAL EXPOSURE; MULTICENTER STUDY; NEWBORN; PREGNANCY; PRESCHOOL CHILD; REGISTER; RISK FACTOR;

ADULT; AGE FACTORS; ANIMALS; ASTHMA; CATS; CHILD; CHILD, PRESCHOOL; FEMALE; FOLLOW-UP STUDIES; GREAT BRITAIN; HUMANS; INFANT; INFANT, NEWBORN; MALE; MATERNAL EXPOSURE; PETS; PREGNANCY; RABBITS; REGISTRIES; RISK FACTORS; RODENTIA;

EID: 84919742356     PISSN: 09547894     EISSN: 13652222     Source Type: Journal    
DOI: 10.1111/cea.12380     Document Type: Article

References (40)

1. Sennhauser FH, Braun-Fahrlander C, Wildhaber JH. The burden of asthma in children: a European perspective. Paediatr Respir Rev 2005; 6:2-7.
2. Wildhaber J, Carroll WD, Brand PL. Global impact of asthma on children and adolescents' daily lives: the room to breathe survey. Pediatr Pulmonol 2012; 47:346-57.
3. Peters JL, Boynton-Jarrett R, Sandel M. Prenatal environmental factors influencing IgE levels, atopy and early asthma. Curr Opin Allergy Clin Immunol 2013; 13:187-92.
4. Blekic M, Kljaic Bukvic B, Aberle N et al. 17q12-21 and asthma: interactions with early-life environmental exposures. Ann Allergy Asthma Immunol 2013; 110:347-53 e342.
5. Gowers AM, Cullinan P, Ayres JG et al. Does outdoor air pollution induce new cases of asthma? Biological plausibility and evidence; a review. Respirology 2012; 17:887-98.
6. Saglani S, Bush A. The early-life origins of asthma. Curr Opin Allergy Clin Immunol 2007; 7:83-90.
7. Pearce N, Douwes J. The global epidemiology of asthma in children. Int J Tuberc Lung Dis 2006; 10:125-32.
8. Anderson HR, Gupta R, Strachan DP, Limb ES. 50 years of asthma: UK trends from 1955 to 2004. Thorax 2007; 62:85-90.
9. Westgarth C, Heron J, Ness AR et al. Family pet ownership during childhood: findings from a UK birth cohort and implications for public health research. Int J Environ Res Public Health 2010; 7:3704-29.
10. Apelberg BJ, Aoki Y, Jaakkola JJ. Systematic review: Exposure to pets and risk of asthma and asthma-like symptoms. J Allergy Clin Immunol 2001; 107:455-60.
11. Takkouche B, Gonzalez-Barcala FJ, Etminan M, Fitzgerald M. Exposure to furry pets and the risk of asthma and allergic rhinitis: a meta-analysis. Allergy 2008; 63:857-64.
12. Lodrup Carlsen KC, Roll S, Carlsen KH et al. Does pet ownership in infancy lead to asthma or allergy at school age? Pooled analysis of individual participant data from 11 European birth cohorts. PLoS One 2012; 7:e43214.
13. von Mutius E. Allergies, infections and the hygiene hypothesis-the epidemiological evidence. Immunobiology 2007; 212:433-9.
14. Douwes J, Brooks C, van Dalen C, Pearce N. Importance of allergy in asthma: an epidemiologic perspective. Curr Allergy Asthma Rep 2011; 11:434-44.
15. Boyd A, Golding J, Macleod J et al. Cohort profile: The 'Children of the 90s'-the index offspring of the Avon longitudinal study of parents and children. Int J Epidemiol 2013; 42:111-27.
16. Fraser A, Macdonald-Wallis C, Tilling K et al. Cohort profile: The Avon longitudinal study of parents and children: ALSPAC mothers cohort. Int J Epidemiol 2013; 42:97-110.
17. Roberts G, Peckitt C, Northstone K et al. Relationship between aeroallergen and food allergen sensitization in childhood. Clin Exp Allergy 2005; 35:933-40.
18. Yan K, Salome C, Woolcock AJ. Rapid method for measurement of bronchial responsiveness. Thorax 1983; 38:760-5.
19. Granell R, Sterne JA, Henderson J. Associations of different phenotypes of wheezing illness in early childhood with environmental variables implicated in the aetiology of asthma. PLoS ONE 2012; 7:e48359.
20. Mishra G, Nitsch D, Black S, De SB, Kuh D, Hardy R. A structured approach to modelling the effects of binary exposure variables over the life course. Int J Epidemiol 2009; 38:528-37.
21. Callard RE, Hamvas R, Chatterton C et al. Parents ASTALSo, children. An interaction between the IL-4Ralpha gene and infection is associated with atopic eczema in young children. Clin Exp Allergy 2002; 32:990-3.
22. Cookson H, Granell R, Joinson C, Ben-Shlomo Y, Henderson AJ. Mothers' anxiety during pregnancy is associated with asthma in their children. J Allergy Clin Immunol 2009; 123(847-853):e811.
23. Shaheen SO, Newson RB, Henderson AJ et al. Umbilical cord trace elements and minerals and risk of early childhood wheezing and eczema. Eur Respir J 2004; 24:292-7.
24. Shaheen SO, Newson RB, Henderson AJ et al. Prenatal paracetamol exposure and risk of asthma and elevated immunoglobulin E in childhood. Clin Exp Allergy 2005; 35:18-25.
25. Shaheen SO, Northstone K, Newson RB, Emmett PM, Sherriff A, Henderson AJ. Dietary patterns in pregnancy and respiratory and atopic outcomes in childhood. Thorax 2009; 64:411-7.
26. Bergmann MM, Jacobs EJ, Hoffmann K, Boeing H. Agreement of self-reported medical history: comparison of an in-person interview with a self-zadministered questionnaire. Eur J Epidemiol 2004; 19:411-6.
27. Smith HE, Hogger C, Lallemant C, Crook D, Frew AJ. Is structured allergy history sufficient when assessing patients with asthma and rhinitis in general practice? J Allergy Clin Immunol 2009; 123:646-50.
28. Henderson J, Granell R, Heron J et al. Associations of wheezing phenotypes in the first 6 years of life with atopy, lung function and airway responsiveness in mid-childhood. Thorax 2008; 63:974-80.
29. Pekkanen J, Lampi J, Genuneit J, Hartikainen AL, Jarvelin MR. Analyzing atopic and non-atopic asthma. Eur J Epidemiol 2012; 27:281-6.
30. Greenland S. Quantifying biases in causal models: classical confounding vs collider-stratification bias. Epidemiology (Cambridge, Mass) 2003; 14:300-6.
31. Cornish RP, Henderson J, Boyd AW, Granell R, Van Staa T, Macleod J. Validating childhood asthma in an epidemiological study using linked electronic patient records. BMJ Open 2014; 4:e005345.
32. Platts-Mills T, Vaughan J, Squillace S, Woodfolk J, Sporik R. Sensitisation, asthma, and a modified Th2 response in children exposed to cat allergen: a population-based cross-sectional study. Lancet 2001; 357:752-6.
33. Erwin EA, Custis N, Ronmark E et al. Asthma and indoor air: contrasts in the dose response to cat and dust-mite. Indoor Air 2005; 15(Suppl 10):33-9.
34. Zahradnik E, Raulf M. Animal allergens and their presence in the environment. Front Immunol 2014; 5:76.
35. Liu AH. Something old, something new: indoor endotoxin, allergens and asthma. Paediatr Respir Rev 2004; 5 (Suppl. A):S65-71.
36. Platts-Mills TA, Woodfolk JA. Allergens and their role in the allergic immune response. Immunol Rev 2011; 242:51-68.
37. Walsh MG. Toxocara infection and diminished lung function in a nationally representative sample from the United States population. Int J Parasitol 2011; 41:243-7.
38. Bisgaard H, Bonnelykke K, Stokholm J. Immune-mediated diseases and microbial exposure in early life. Clin Exp Allergy 2014; 44:475-81.
39. Herzog H. The impact of pets on human health and psychological well-being: fact, fiction, or hypothesis? Curr Dir Psychol Sci 2011; 20:236-9.
40. Spycher BD, Henderson J, Granell R et al. Genome-wide prediction of childhood asthma and related phenotypes in a longitudinal birth cohort. J Allergy Clin Immunol 2012; 130:503-9.