A randomized, three-period crossover study of umeclidinium as monotherapy in adult patients with asthma

Respiratory Medicine

Volumn 109, Issue 1, 2015, Pages 63-73

  Lee, Laurie A ^a   Briggs, Anne ^b   Edwards, Lisa D ^a   Yang, Shuying ^b   Pascoe, Steven ^a  

^a GLAXOSMITHKLINE   (United States)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Asthma; Fixed dose combination; Inhaled corticosteroid; Muscarinic antagonist; Trough FEV1

Indexed keywords

PLACEBO; UMECLIDINIUM; BRONCHODILATING AGENT; MUSCARINIC RECEPTOR BLOCKING AGENT; QUINUCLIDINE DERIVATIVE;

ABNORMAL LABORATORY RESULT; ADULT; AREA UNDER THE CURVE; ARTICLE; ASTHMA; CONTROLLED STUDY; CROSSOVER PROCEDURE; DISEASE EXACERBATION; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG ABSORPTION; DRUG EFFICACY; DRUG SAFETY; DRUG WITHDRAWAL; EYELID EDEMA; FEMALE; FORCED EXPIRATORY VOLUME; HEADACHE; HUMAN; MAJOR CLINICAL STUDY; MALE; MAXIMUM PLASMA CONCENTRATION; MIDDLE AGED; MONOTHERAPY; MULTICENTER STUDY; MYALGIA; PHARYNGITIS; PREDICTIVE VALUE; RANDOMIZED CONTROLLED TRIAL; RHINOPHARYNGITIS; SPIROMETRY; SUPRAVENTRICULAR TACHYCARDIA; T WAVE INVERSION; TASTE DISORDER; THROAT IRRITATION; TIME TO MAXIMUM PLASMA CONCENTRATION; YOUNG ADULT; ADOLESCENT; CLINICAL TRIAL; DRUG EFFECTS; INHALATIONAL DRUG ADMINISTRATION; METABOLISM; PATHOPHYSIOLOGY; TREATMENT OUTCOME;

ADMINISTRATION, INHALATION; ADOLESCENT; ADULT; ASTHMA; BRONCHODILATOR AGENTS; CROSS-OVER STUDIES; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; FEMALE; FORCED EXPIRATORY VOLUME; HUMANS; MALE; MIDDLE AGED; MUSCARINIC ANTAGONISTS; QUINUCLIDINES; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84919725824     PISSN: 09546111     EISSN: 15323064     Source Type: Journal    
DOI: 10.1016/j.rmed.2014.10.009     Document Type: Article

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