miR-451 inhibits invasion and proliferation of bladder cancer by regulating EMT

International Journal of Clinical and Experimental Pathology

Volumn 7, Issue 11, 2014, Pages 7653-7662

  Zeng, Tao ^a,b   Peng, Lifen ^b   Chao, Chaohai ^a   Fu, Bin ^a   Wang, Gongxian ^a   Wang, Yibing ^a   Zhu, Xinshen ^b  

^a NANCHANG UNIVERSITY   (China)

^b People's Hospital of Jiangxi Province   (China)

Author keywords

Bladder cancer; EMT; miR 451

Indexed keywords

CADHERIN; MICRORNA; MIRN451 MICRORNA, HUMAN; SNAIL FAMILY TRANSCRIPTION FACTORS; TRANSCRIPTION FACTOR; VIMENTIN;

BLADDER TUMOR; CELL ADHESION; CELL MOTION; CELL PROLIFERATION; DOWN REGULATION; EPITHELIAL MESENCHYMAL TRANSITION; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; PATHOLOGY; TUMOR CELL LINE;

CADHERINS; CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; DOWN-REGULATION; EPITHELIAL-MESENCHYMAL TRANSITION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MICRORNAS; TRANSCRIPTION FACTORS; URINARY BLADDER NEOPLASMS; VIMENTIN;

EID: 84919664604     PISSN: None     EISSN: 19362625     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Jemal A, Bray F, Center MM, Ferlay J, Ward E and Forman D. Global cancer statistics. CA Cancer J Clin 2011; 61: 69-90.
2. Nargund VH, Tanabalan CK and Kabir MN. Management of non-muscle-invasive (superficial) bladder cancer. Semin Oncol 2012; 39: 13.
3. Bartel DP. MicroRNAs: target recognition and regulatory functions. Cell 2009; 136: 215-233.
4. Rosenfeld N, Aharonov R, Meiri E, Rosenwald S, Spector Y, Zepeniuk M, Benjamin H, Shabes N, Tabak S and Levy A. MicroRNAs accurately identify cancer tissue origin. Nat Biotechnol 2008; 26: 462-469.
5. Chan JK, Blansit K, Kiet T, Sherman A, Wong G, Earle C and Bourguignon LY. The inhibition of miR-21 promotes apoptosis and chemosensitivity in ovarian cancer. Gynecol Oncol 2014; 132: 739-744.
6. Zhang JG, Wang JJ, Zhao F, Liu Q, Jiang K and Yang GH. MicroRNA-21 (miR-21) represses tumor suppressor PTEN and promotes growth and invasion in non-small cell lung cancer (NSCLC). Clin Chim Acta 2010; 411: 846-852.
7. Xia Y, Wu Y, Liu B, Wang P and Chen Y. Downregulation of miR-638 promotes invasion and proliferation by regulating SOX2 and induces EMT in NSCLC. FEBS Lett 2014; 588: 2238-2245.
8. Engelsvold DH, Utheim TP, Olstad OK, Gonzalez P, Eidet JR, Lyberg T, Trøseid AMS, Dartt DA and Raeder S. miRNA and mRNA expression profiling identifies members of the miR-200 family as potential regulators of epithelial-mesenchymal transition in pterygium. Expe Eye Res 2013; 115: 189-198.
9. Li Y, Wang H, Tao K, Xiao Q, Huang Z, Zhong L, Cao W, Wen J and Feng W. miR-29b suppresses CML cell proliferation and induces apoptosis via regulation of BCR/ABL1 protein. Exp Cell Res 2013; 319: 1094-1101.
10. Uchida Y, Chiyomaru T, Enokida H, Kawakami K, Tatarano S, Kawahara K, Nishiyama K, Seki N and Nakagawa M. MiR-133a induces apoptosis through direct regulation of GSTP1 in bladder cancer cell lines. Urol Oncol 2013; 31: 115-123.
11. Zhu X, Li Y, Shen H, Li H, Long L, Hui L and Xu W. miR-137 inhibits the proliferation of lung cancer cells by targeting Cdc42 and Cdk6. FEBS Lett 2013; 587: 73-81.
12. Bo K, Yang G, Chong D, Qi S, Shan X, Chen-Qing W, Xinyang W, Dalin H and Peng G. miR-145 inhibits invasion of bladder cancer cells by targeting PAK1. Urol Oncol 2014; 32: 846-54.
13. Chen L, Dai YM, Ji CB, Yang L, Shi CM, Xu GF, Pang LX, Huang FY, Zhang CM and Guo XR. MiR-146b is a regulator of human visceral preadipocyte proliferation and differentiation and its expression is altered in human obesity. Mol Cell Endocrinol 2014; 393: 65-74.
14. Dong L, Cong L, Xiyin W, Sigurdur I and Huiping C. MicroRNA-451 suppresses tumor cell growth by down-regulating IL6R gene expression. Cancer Epidemiol 2014; 38: 7.
15. Bandres E, Bitarte N, Arias F, Agorreta J, Fortes P, Agirre X, Zarate R, Diaz-Gonzalez JA, Ramirez N and Sola JJ. microRNA-451 regulates macrophage migration inhibitory factor production and proliferation of gastrointestinal cancer cells. Clin Cancer Res 2009; 15: 2281-2290.
16. Gal H, Pandi G, Kanner AA, Ram Z, Lithwick-Yanai G, Amariglio N, Rechavi G and Givol D. MIR-451 and Imatinib mesylate inhibit tumor growth of Glioblastoma stem cells. Biochem Biophys Res Commun 2008; 376: 86-90.
17. Heldin CH, Landström M and Moustakas A. Mechanism of TGF-ß signaling to growth arrest, apoptosis, and epithelial-mesenchymal transition. Curr Opin Cell Biol 2009; 21: 166-176.
18. Thiery JP, Acloque H, Huang RY and Nieto MA. Epithelial-mesenchymal transitions in development and disease. Cell 2009; 139: 871-890.
19. Mahlamäki EH , Bärlund M, Tanner M, Gorunova L, Höglund M, Karhu R, Kallioniemi A. Frequent amplification of 8q24, 11q, 17q, and 20q-specific genes in pancreatic cancer. Genes Chromosomes Cancer 2002; 35: 353-341.
20. Varis A, Wolf M, Monni O, Vakkari ML, Kokkola A, Moskaluk C, Frierson H, Powell SM, Knuutila S, Kallioniemi A and El-Rifai W. Targets of gene amplification and overexpression at 17q in gastric cancer. Cancer Res 2002; 62: 2625-2634.
21. Kim Y, Roh S, Lawler S and Friedman A. miR451 and AMPK mutual antagonism in glioma cell migration and proliferation: a mathematical model. PLoS One 2011; 6: e28293.