Detecting Functional Divergence after Gene Duplication through Evolutionary Changes in Posttranslational Regulatory Sequences

PLoS Computational Biology

Volumn 10, Issue 12, 2014, Pages

  Nguyen Ba, Alex N ^a,b   Strome, Bob ^a   Hua, Jun Jie ^a   Desmond, Jonathan ^a   Gagnon Arsenault, Isabelle ^c   Weiss, Eric L ^d   Landry, Christian R ^c   Moses, Alan M ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITÉ LAVAL   (Canada)

^d NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYMATIC ACTIVITIES; EVOLUTIONARY CHANGES; EVOLUTIONARY MECHANISMS; FUNCTIONALIZATIONS; GENE DUPLICATIONS; MOLECULAR FUNCTION; NEW FUNCTIONS; PARALOGS; POSTTRANSLATIONAL REGULATION; REGULATORY SEQUENCES;

GENES;

ACE2 GENE; ARTICLE; CANDIDA ALBICANS; CANDIDA GLABRATA; CANDIDA PARAPSILOSIS; CANDIDA TROPICALIS; CBK1 GENE; CELLULAR DISTRIBUTION; CLAVISPORA LUSITANIAE; CONTROLLED STUDY; DEBARYOMYCES HANSENII; EREMOTHECIUM; FKH1 GENE; FKH2 GENE; GENE; GENE DUPLICATION; GENETIC VARIABILITY; KLUYVEROMYCES LACTIS; LACHANCEA KLUYVERI; MEYEROZYMA GUILLIERMONDII; MOLECULAR EVOLUTION; NONHUMAN; NUCLEOTIDE MOTIF; PARALOGY; RCK1 GENE; RCK2 GENE; REGULATORY SEQUENCE; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES UVARUM; SEQUENCE ALIGNMENT; SWI5 GENE; TORULASPORA; YEAST; ZYGOSACCHAROMYCES ROUXII; AMINO ACID SEQUENCE; BIOLOGICAL MODEL; BIOLOGY; BUDDING YEAST; COMPUTER SIMULATION; DNA SEQUENCE; GENETICS; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PROTEIN PROCESSING;

SACCHAROMYCETALES;

AMINO ACID SEQUENCE; BASE SEQUENCE; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; EVOLUTION, MOLECULAR; GENE DUPLICATION; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; PROTEIN PROCESSING, POST-TRANSLATIONAL; REGULATORY SEQUENCES, NUCLEIC ACID; SACCHAROMYCETALES; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, DNA;

EID: 84919628504     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1003977     Document Type: Article

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