Danzhi Xiaoyao San ameliorates depressive-like behavior by shifting toward serotonin via the downregulation of hippocampal indoleamine 2,3-dioxygenase

Journal of Ethnopharmacology

Volumn 160, Issue , 2015, Pages 86-93

  Zhu, Xiaoxia ^a   Jing, Linlin ^a   Chen, Chun ^a   Shao, Meng ^a   Fan, Qin ^a   Diao, Jianxin ^a   Liu, Yuanliang ^a   Lv, Zhiping ^a   Sun, Xuegang ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

Cytokine; Danzhi Xiaoyao San; Depressive like behavior; Hippocampus; Indoleamine 2,3 dioxygenase; Tryptophan catabolite

Indexed keywords

CHINESE DRUG; DANZHI XIAOYAO SAN; FERULIC ACID; FLUOXETINE; GAMMA INTERFERON; GARDENOSIDE; INDOLEAMINE 2,3 DIOXYGENASE; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 6; KYNURENINE; LIGUSTILIDE; PAENIFLORIN; PEONOL; PLANT MEDICINAL PRODUCT; SEROTONIN; SUCROSE; TRYPTOPHAN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ANTIDEPRESSANT AGENT; CYTOKINE; DANZHI XIAOYAO; HERBACEOUS AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDEPRESSANT ACTIVITY; ARTICLE; BODY WEIGHT; CHRONIC STRESS; CHRONIC UNPREDICTABLE MILD STRESS; CONTROLLED STUDY; DEPRESSION; DOWN REGULATION; ELECTROSPRAY MASS SPECTROMETRY; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; EXTRACTION; HIPPOCAMPUS; LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; RAT; SUCROSE PREFERENCE TEST; UPREGULATION; WESTERN BLOTTING; ANIMAL; ANIMAL BEHAVIOR; BIOSYNTHESIS; BLOOD; DRUG EFFECTS; ENZYMOLOGY; METABOLISM; MOTOR ACTIVITY;

RATTUS;

ANIMALS; ANTIDEPRESSIVE AGENTS; BEHAVIOR, ANIMAL; CYTOKINES; DOWN-REGULATION; DRUGS, CHINESE HERBAL; FLUOXETINE; HIPPOCAMPUS; INDOLEAMINE-PYRROLE 2,3,-DIOXYGENASE; KYNURENINE; MALE; MOTOR ACTIVITY; RATS; SEROTONIN; TRYPTOPHAN; UP-REGULATION;

EID: 84919624623     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2014.11.031     Document Type: Article

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