Permissive changes in the neuraminidase play a dominant role in improving the viral fitness of oseltamivir-resistant seasonal influenza A(H1N1) strains

Antiviral Research

Volumn 114, Issue , 2015, Pages 57-61

  Abed, Yacine ^a   Pizzorno, Andrés ^a   Bouhy, Xavier ^a   Boivin, Guy ^a  

^a LAVAL UNIVERSITY   (Canada)

Author keywords

Fitness; H1N1; Influenza; Neuraminidase; Oseltamivir; Resistance

Indexed keywords

N ACETYLNEURAMINIC ACID; OSELTAMIVIR; SIALIDASE; ANTIVIRUS AGENT; NA PROTEIN, INFLUENZA A VIRUS; VIRUS PROTEIN;

ANTIVIRAL RESISTANCE; ARTICLE; CONTROLLED STUDY; GENETIC REASSORTMENT; GENETIC VARIABILITY; GENOTYPE; HUMAN; INFLUENZA A (H1N1); INFLUENZA VIRUS A H1N1; NONHUMAN; NUCLEOTIDE SEQUENCE; REVERTANT; SEASONAL INFLUENZA; VIRUS RECOMBINANT; VIRUS REPLICATION; VIRUS STRAIN; WILD TYPE; DRUG EFFECTS; GENETICS; INFLUENZA; METABOLISM; MISSENSE MUTATION; PHYSIOLOGY; REPRODUCTIVE FITNESS; SEASON; VIROLOGY; VIRUS LOAD;

ANTIVIRAL AGENTS; DRUG RESISTANCE, VIRAL; GENETIC FITNESS; HUMANS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA, HUMAN; MUTATION, MISSENSE; NEURAMINIDASE; OSELTAMIVIR; SEASONS; VIRAL LOAD; VIRAL PROTEINS; VIRUS REPLICATION;

EID: 84919623122     PISSN: 01663542     EISSN: 18729096     Source Type: Journal    
DOI: 10.1016/j.antiviral.2014.12.006     Document Type: Article

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