Emergence of oseltamivir-resistant pandemic H1N1 virus during prophylaxis

New England Journal of Medicine

Volumn 361, Issue 23, 2009, Pages 2296-2297

  Baz, Mariana ^a   Abed, Yacine ^a   Papenburg, Jesse ^a   Bouhy, Xavier ^a   Hamelin, Marie Ève ^a   Boivin, Guy ^a  

^a LAVAL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

OSELTAMIVIR; ZANAMIVIR; ANTIVIRUS AGENT; ENZYME INHIBITOR; SIALIDASE;

ADOLESCENT; ADULT; ANTIVIRAL THERAPY; CASE REPORT; CLINICAL FEATURE; HUMAN; INFLUENZA; INFLUENZA VIRUS A H1N1; LETTER; MALE; NASOPHARYNGEAL ASPIRATION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROPHYLAXIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ANTIVIRAL RESISTANCE; ASTHMA; CHEMOPROPHYLAXIS; CHRONIC OBSTRUCTIVE LUNG DISEASE; DRUG ANTAGONISM; DRUG EFFECT; EPIDEMIC; GENETICS; ISOLATION AND PURIFICATION; MICROBIOLOGICAL EXAMINATION; MUTATION;

ADOLESCENT; ANTIVIRAL AGENTS; ASTHMA; CHEMOPREVENTION; DISEASE OUTBREAKS; DRUG RESISTANCE, VIRAL; ENZYME INHIBITORS; HUMANS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA, HUMAN; MALE; MICROBIAL SENSITIVITY TESTS; MUTATION; NEURAMINIDASE; OSELTAMIVIR; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE;

EID: 73349123478     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMc0910060     Document Type: Letter

References (5)

1. Updated interim recommendations for the use of antiviral medications in the treatment and prevention of influenza for the 2009-2010 season. Atlanta: Centers for Disease Control and Prevention. (Accessed November 9, 2009, at http://www.cdc.gov/h1n1flu/recommendations.htm.)
2. Abed Y, Goyette N, Boivin G. A reverse genetics study of resistance to neuraminidase inhibitors in an influenza A/H1N1 virus. Antivir Ther 2004;9:577-81.
3. Dharan NJ, Gubareva LV, Meyer JJ, et al. Infections with oseltamivir-resistant influenza A(H1N1) virus in the United States. JAMA 2009;301:1034-41.
4. de Jong MD, Tran TT, Truong HK, et al. Oseltamivir resistance during treatment of influenza A (H5N1) infection. N Engl J Med 2005;353:2667-72.
5. Antiviral use and the risk of drug resistance: pandemic (H1N1) 2009 briefing note 12. Geneva: World Health Organization, September 25, 2009. (Accessed November 9, 2009, at http://www.who.int/csr/disease/swineflu/notes/ h1n1-antiviral-use-20090925/en/index.html.)