Role of permissive neuraminidase mutations in influenza A/Brisbane/59/2007-like (H1N1) viruses

PLoS Pathogens

Volumn 7, Issue 12, 2011, Pages

  Abed, Yacine ^a   Pizzorno, Andrés ^a   Bouhy, Xavier ^a   Boivin, Guy ^a  

^a LAVAL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

SIALIDASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; BINDING AFFINITY; CELL SURFACE; DISEASE TRANSMISSION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME KINETICS; FLUOROMETRY; GENE MUTATION; IC 50; IN VITRO STUDY; IN VIVO STUDY; INFLUENZA VIRUS A H1N1; MALE; NONHUMAN; PROTEIN EXPRESSION; VIRUS REPLICATION; VIRUS STRAIN; ANIMAL; ANTIVIRAL RESISTANCE; FERRET; GENETICS; METABOLISM; MUTATION; ORTHOMYXOVIRUS INFECTION; PATHOGENICITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

MUSTELA; ORTHOMYXOVIRIDAE;

ANIMALS; DRUG RESISTANCE, VIRAL; FERRETS; INFLUENZA A VIRUS, H1N1 SUBTYPE; MUTATION; NEURAMINIDASE; ORTHOMYXOVIRIDAE INFECTIONS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; VIRUS REPLICATION;

EID: 84855259703     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002431     Document Type: Article

References (27)

1. Reid AH, Fanning TG, Janczewski TA, Taubenberger JK, (2000) Characterization of the 1918 "Spanish" influenza virus neuraminidase gene. Proc Natl Acad Sci USA 97: 6785-6790.
2. Boltz DA, Aldridge JR Jr, Webster RG, Govorkova EA, (2010) Drugs in development for influenza. Drugs 70: 1349-1362.
3. Colman PM, Hoyne PA, Lawrence MC, (1993) Sequence and structure alignment of paramyxovirus hemagglutinin-neuraminidase with influenza virus neuraminidase. J Virol 67: 2972-2980.
4. Lackenby A, Hungnes O, Dudman SG, Meijer A, Paget WJ, et al. (2008) Emergence of resistance to oseltamivir among influenza A(H1N1) viruses in Europe. 13 Euro Surveill pii: 8026.
5. Hurt AC, Ernest J, Deng YM, Iannello P, Besselaar TG, et al. (2009) Emergence and spread of oseltamivir-resistant A(H1N1) influenza viruses in Oceania, South East Asia and South Africa. Antiviral Res 83: 90-93.
6. Hauge SH, Dudman S, Borgen K, Lackenby A, Hungnes O, (2009) Oseltamivir-resistant influenza viruses A (H1N1), Norway, 2007-08. Emerg Infect Dis 15: 155-162.
7. Dharan NJ, Gubareva LV, Meyer JJ, Okomo-Adhiambo M, McClinton RC, et al. (2009) Infections with oseltamivir-resistant influenza A(H1N1) virus in the United States. Jama 301: 1034-1041.
8. Herlocher ML, Truscon R, Elias S, Yen HL, Roberts NA, et al. (2004) Influenza viruses resistant to the antiviral drug oseltamivir: transmission studies in ferrets. J Infect Dis 190: 1627-1630.
9. Ives JA, Carr JA, Mendel DB, Tai CY, Lambkin R, et al. (2002) The H274Y mutation in the influenza A/H1N1 neuraminidase active site following oseltamivir phosphate treatment leave virus severely compromised both in vitro and in vivo. Antiviral Res 55: 307-317.
10. Baz M, Abed Y, Simon P, Hamelin ME, Boivin G, (2010) Effect of the neuraminidase mutation H274Y conferring resistance to oseltamivir on the replicative capacity and virulence of old and recent human influenza A(H1N1) viruses. J Infect Dis 201: 740-745.
11. Rameix-Welti MA, Enouf V, Cuvelier F, Jeannin P, van der Werf S, (2008) Enzymatic properties of the neuraminidase of seasonal H1N1 influenza viruses provide insights for the emergence of natural resistance to oseltamivir. PLoS Pathog 4: e1000103.
12. Collins PJ, Haire LF, Lin YP, Liu J, Russell RJ, et al. (2009) Structural basis for oseltamivir resistance of influenza viruses. Vaccine 27: 6317-6323.
13. Bloom JD, Gong LI, Baltimore D, (2010) Permissive secondary mutations enable the evolution of influenza oseltamivir resistance. Science 328: 1272-1275.
14. Hayden FG, Palese P, (2002) Influenza virus. In: Douglas RWJ, Richman D, Hayden FG, editors. Clinical Virology. 2nd edition. Washington DC ASM Press pp. 891-920.
15. Palese P, Compans RW, (1976) Inhibition of influenza virus replication in tissue culture by 2-deoxy-2,3-dehydro-N-trifluoroacetylneuraminic acid (FANA): mechanism of action. J Gen Virol 33: 159-163.
16. Hensley SE, Das SR, Gibbs JS, Bailey AL, Schmidt LM, et al. (2011) Influenza a virus hemagglutinin antibody escape promotes neuraminidase antigenic variation and drug resistance. PLoS One 6: e15190.
17. Russell RJ, Haire LF, Stevens DJ, Collins PJ, Lin YP, et al. (2006) The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design. Nature 443: 45-49.
18. Kryazhimskiy S, Dushoff J, Bazykin GA, Plotkin JB, (2011) Prevalence of epistasis in the evolution of influenza a surface proteins. PLoS Genet 7: e1001301.
19. Yang JR, Lin YC, Huang YP, Su CH, Lo J, et al. (2011) Reassortment and mutations associated with emergence and spread of oseltamivir-resistant seasonal influenza A/H1N1 viruses in 2005-2009. PLoS One 6: e18177.
20. Bloom JD, Nayak JS, Baltimore D, (2011) A computational-experimental approach identifies mutations that enhance surface expression of an oseltamivir-resistant influenza neuraminidase. PLoS One 6: e22201.
21. Hoffmann E, Stech J, Guan Y, Webster RG, Perez DR, (2001) Universal primer set for the full-length amplification of all influenza A viruses. Arch Virol 146: 2275-2289.
22. Liu Q, Wang S, Ma G, Pu J, Forbes NE, et al. (2009) Improved and simplified recombineering approach for influenza virus reverse genetics. J Mol Genet Med 3: 225-231.
23. Abed Y, Baz M, Boivin G, (2006) Impact of neuraminidase mutations conferring influenza resistance to neuraminidase inhibitors in the N1 and N2 genetic backgrounds. Antivir Ther 11: 971-976.
24. Duan S, Boltz DA, Seiler P, Li J, Bragstad K, et al. (2010) Oseltamivir-resistant pandemic H1N1/2009 influenza virus possesses lower transmissibility and fitness in ferrets. PLoS Pathog 6: e1001022.
25. Pizzorno A, Bouhy X, Abed Y, Boivin G, (2011) Generation and characterization of recombinant pandemic influenza A(H1N1) viruses resistant to neuraminidase inhibitors. J Infect Dis 203: 25-31.
26. Abed Y, Goyette N, Boivin G, (2004) A reverse genetics study of resistance to neuraminidase inhibitors in an influenza A/H1N1 virus. Antivir Ther 9: 577-581.
27. Hamelin ME, Baz M, Abed Y, Couture C, Joubert P, et al. (2010) Oseltamivir-resistant pandemic A/H1N1 virus is as virulent as its wild-type counterpart in mice and ferrets. PLoS Pathog 6: e1001015.