Cornea-infiltrating and lymph node dendritic cells contribute to CD4+ T cell expansion after herpes simplex virus-1 ocular infection

Journal of Immunology

Volumn 194, Issue 1, 2015, Pages 379-387

  Buela, Kristine Ann G ^a   Hendricks, Robert L ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIPHTHERIA TOXIN RECEPTOR; GLYCOPROTEIN P 15095; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; RECEPTOR; UNCLASSIFIED DRUG; DIPHTHERIA TOXIN; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; HLA ANTIGEN CLASS 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ T LYMPHOCYTE; CELL EXPANSION; CONTROLLED STUDY; CORNEA INFILTRATING DENDRITIC CELL; DENDRITIC CELL; DEPLETION; DRAINING LYMPH NODE DENDRITIC CELL; FEMALE; HERPES SIMPLEX KERATITIS; HERPES SIMPLEX VIRUS 1; MOUSE; NONHUMAN; PROMOTER REGION; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; C57BL MOUSE; CELL DIFFERENTIATION; CORNEA; CYTOLOGY; EPITHELIUM CELL; GENETICS; IMMUNOLOGY; LYMPH NODE; MACROPHAGE; PATHOLOGY; TRANSGENIC MOUSE; VIROLOGY;

ANIMALS; ANTIGENS, CD11C; CD4-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CORNEA; DENDRITIC CELLS; DIPHTHERIA TOXIN; EPITHELIAL CELLS; FEMALE; HEPARIN-BINDING EGF-LIKE GROWTH FACTOR; HERPESVIRUS 1, HUMAN; HISTOCOMPATIBILITY ANTIGENS CLASS II; KERATITIS, HERPETIC; LYMPH NODES; MACROPHAGES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, TRANSGENIC; PROMOTER REGIONS, GENETIC;

EID: 84919607800     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1402326     Document Type: Article

References (36)

1. Streilein, J. W. 2003. Ocular immune privilege: Therapeutic opportunities from an experiment of nature. Nat. Rev. Immunol. 3: 879-889.
2. Knickelbein, J. E., S. C. Watkins, P. G. McMenamin, and R. L. Hendricks. 2009. Stratification of antigen-presenting cells within the normal cornea. Ophthalmol. Eye Dis. 1: 45-54.
3. Knickelbein, J. E., K. A. Buela, and R. L. Hendricks. 2014. Antigenpresenting cells are stratified within normal human corneas and are rapidly mobilized during ex vivo viral infection. Invest. Ophthalmol. Vis. Sci. 55: 1118-1123.
4. Tang, Q., and R. L. Hendricks. 1996. Interferon gamma regulates platelet endothelial cell adhesion molecule 1 expression and neutrophil infiltration into herpes simplex virus-infected mouse corneas. J. Exp. Med. 184: 1435-1447.
5. Stumpf, T. H., C. Shimeld, D. L. Easty, and T. J. Hill. 2001. Cytokine production in a murine model of recurrent herpetic stromal keratitis. Invest. Ophthalmol. Vis. Sci. 42: 372-378.
6. Frank, G. M., S. J. Divito, D. M. Maker, M. Xu, and R. L. Hendricks. 2010. A novel p40-independent function of IL-12p35 is required for progression and maintenance of herpes stromal keratitis. Invest. Ophthalmol. Vis. Sci. 51: 3591-3598.
7. Duan, R., L. Remeijer, J. M. van Dun, A. D. Osterhaus, and G. M. Verjans. 2007. Granulocyte macrophage colony-stimulating factor expression in human herpetic stromal keratitis: Implications for the role of neutrophils in HSK. Invest. Ophthalmol. Vis. Sci. 48: 277-284.
8. Maertzdorf, J., A. D. M. E. Osterhaus, and G. M. G. M. Verjans. 2002. IL-17 expression in human herpetic stromal keratitis: Modulatory effects on chemokine production by corneal fibroblasts. J. Immunol. 169: 5897-5903.
9. Suryawanshi, A., T. Veiga-Parga, N. K. Rajasagi, P. B. Reddy, S. Sehrawat, S. Sharma, and B. T. Rouse. 2011. Role of IL-17 and Th17 cells in herpes simplex virus-induced corneal immunopathology. J. Immunol. 187: 1919- 1930.
10. Foti, M., F. Granucci, and P. Ricciardi-Castagnoli. 2004. A central role for tissueresident dendritic cells in innate responses. Trends Immunol. 25: 650-654.
11. Heath, W. R., and F. R. Carbone. 2013. The skin-resident and migratory immune system in steady state and memory: Innate lymphocytes, dendritic cells and T cells. Nat. Immunol. 14: 978-985.
12. Foti, M., F. Granucci, M. Pelizzola, O. Beretta, and P. Ricciardi-Castagnoli. 2006. Dendritic cells in pathogen recognition and induction of immune responses: A functional genomics approach. J. Leukoc. Biol. 79: 913-916.
13. Frank, G. M., K. A. Buela, D. M. Maker, S. A. Harvey, and R. L. Hendricks. 2012. Early responding dendritic cells direct the local NK response to control herpes simplex virus 1 infection within the cornea. J. Immunol. 188: 1350-1359.
14. Lepisto, A. J., G. M. Frank, M. Xu, P. M. Stuart, and R. L. Hendricks. 2006. CD8 T cells mediate transient herpes stromal keratitis in CD4-deficient mice. Invest. Ophthalmol. Vis. Sci. 47: 3400-3409.
15. Yun, H., A. M. Rowe, K. L. Lathrop, S. A. Harvey, and R. L. Hendricks. 2014. Reversible nerve damage and corneal pathology in murine herpes simplex stromal keratitis. J. Virol. 88: 7870-7880.
16. Hendricks, R. L., and T. M. Tumpey. 1990. Contribution of virus and immune factors to herpes simplex virus type I-induced corneal pathology. Invest. Ophthalmol. Vis. Sci. 31: 1929-1939.
17. Divito, S. J., and R. L. Hendricks. 2008. Activated inflammatory infiltrate in HSV-1-infected corneas without herpes stromal keratitis. Invest. Ophthalmol. Vis. Sci. 49: 1488-1495.
18. Hendricks, R. L., M. Janowicz, and T. M. Tumpey. 1992. Critical role of corneal Langerhans cells in the CD4- but not CD8-mediated immunopathology in herpes simplex virus-1-infected mouse corneas. J. Immunol. 148: 2522-2529.
19. Zammit, D. J., L. S. Cauley, Q. M. Pham, and L. Lefrancois. 2005. Dendritic cells maximize the memory CD8 T cell response to infection. Immunity 22: 561-570.
20. Schindelin, J., I. Arganda-Carreras, E. Frise, V. Kaynig, M. Longair, T. Pietzsch, S. Preibisch, C. Rueden, S. Saalfeld, B. Schmid, et al. 2012. Fiji: An open-source platform for biological-image analysis. Nat. Methods 9: 676-682.
21. Lee, H. K., M. Zamora, M. M. Linehan, N. Iijima, D. Gonzalez, A. Haberman, and A. Iwasaki. 2009. Differential roles of migratory and resident DCs in T cell priming after mucosal or skin HSV-1 infection. J. Exp. Med. 206: 359-370.
22. Wikstrom, M. E., and P. A. Stumbles. 2007. Mouse respiratory tract dendritic cell subsets and the immunological fate of inhaled antigens. Immunol. Cell Biol. 85: 182-188.
23. Nakano, H., K. L. Lin, M. Yanagita, C. Charbonneau, D. N. Cook, T. Kakiuchi, and M. D. Gunn. 2009. Blood-derived inflammatory dendritic cells in lymph nodes stimulate acute T helper type 1 immune responses. Nat. Immunol. 10: 394-402.
24. Gebhardt, T., P. G. Whitney, A. Zaid, L. K. Mackay, A. G. Brooks, W. R. Heath, F. R. Carbone, and S. N. Mueller. 2011. Different patterns of peripheral migration by memory CD4+ and CD8+ T cells. Nature 477: 216-219.
25. Lee, E. J., J. T. Rosenbaum, and S. R. Planck. 2010. Epifluorescence intravital microscopy of murine corneal dendritic cells. Invest. Ophthalmol. Vis. Sci. 51: 2101-2108.
26. Liu, Y., P. Hamrah, Q. Zhang, A. W. Taylor, and M. R. Dana. 2002. Draining lymph nodes of corneal transplant hosts exhibit evidence for donor major histocompatibility complex (MHC) class II-positive dendritic cells derived from MHC class II-negative grafts. J. Exp. Med. 195: 259-268.
27. Kruse, M., O. Rosorius, F. Krätzer, G. Stelz, C. Kuhnt, G. Schuler, J. Hauber, and A. Steinkasserer. 2000. Mature dendritic cells infected with herpes simplex virus type 1 exhibit inhibited T-cell stimulatory capacity. J. Virol. 74: 7127-7136.
28. Mikloska, Z., L. Bosnjak, and A. L. Cunningham. 2001. Immature monocytederived dendritic cells are productively infected with herpes simplex virus type 1. J. Virol. 75: 5958-5964.
29. Salio, M., M. Cella, M. Suter, and A. Lanzavecchia. 1999. Inhibition of dendritic cell maturation by herpes simplex virus. Eur. J. Immunol. 29: 3245-3253.
30. Samady, L., E. Costigliola, L. MacCormac, Y. McGrath, S. Cleverley, C. E. Lilley, J. Smith, D. S. Latchman, B. Chain, and R. S. Coffin. 2003. Deletion of the virion host shutoff protein (vhs) from herpes simplex virus (HSV) relieves the viral block to dendritic cell activation: Potential of vhs- HSV vectors for dendritic cell-mediated immunotherapy. J. Virol. 77: 3768-3776.
31. Allenspach, E. J., M. P. Lemos, P. M. Porrett, L. A. Turka, and T. M. Laufer. 2008. Migratory and lymphoid-resident dendritic cells cooperate to efficiently prime naive CD4 T cells. Immunity 29: 795-806.
32. Mueller, S. N., C. M. Jones, C. M. Smith, W. R. Heath, and F. R. Carbone. 2002. Rapid cytotoxic T lymphocyte activation occurs in the draining lymph nodes after cutaneous herpes simplex virus infection as a result of early antigen presentation and not the presence of virus. J. Exp. Med. 195: 651-656.
33. Chen, H., and R. L. Hendricks. 1998. B7 costimulatory requirements of T cells at an inflammatory site. J. Immunol. 160: 5045-5052.
34. Seo, S. K., H. Y. Park, J. H. Choi, W. Y. Kim, Y. H. Kim, H. W. Jung, B. Kwon, H. W. Lee, and B. S. Kwon. 2003. Blocking 4-1BB/4-1BB ligand interactions prevents herpetic stromal keratitis. J. Immunol. 171: 576-583.
35. Xu, M., A. J. Lepisto, and R. L. Hendricks. 2004. CD154 signaling regulates the Th1 response to herpes simplex virus-1 and inflammation in infected corneas. J. Immunol. 173: 1232-1239.
36. Iijima, N., L. M. Mattei, and A. Iwasaki. 2011. Recruited inflammatory monocytes stimulate antiviral Th1 immunity in infected tissue. Proc. Natl. Acad. Sci. USA 108: 284-289.