메뉴 건너뛰기




Volumn 356, Issue 2, 2015, Pages 962-970

MiR-1181 inhibits stem cell-like phenotypes and suppresses SOX2 and STAT3 in human pancreatic cancer

Author keywords

Cancer stem cells; MiR 1181; Pancreatic cancer; SOX2; STAT3

Indexed keywords

MICRORNA; MICRORNA 1181; STAT3 PROTEIN; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG; MESSENGER RNA; SMALL INTERFERING RNA; SOX2 PROTEIN, HUMAN; STAT3 PROTEIN, HUMAN; TRANSCRIPTION FACTOR SOX;

EID: 84919499625     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2014.11.007     Document Type: Article
Times cited : (64)

References (42)
  • 2
    • 77951755278 scopus 로고    scopus 로고
    • Pancreatic cancer
    • Hidalgo M. Pancreatic cancer. N. Engl. J. Med 2010, 362:1605-1617.
    • (2010) N. Engl. J. Med , vol.362 , pp. 1605-1617
    • Hidalgo, M.1
  • 4
    • 80455127294 scopus 로고    scopus 로고
    • Common cancer stem cell gene variants predict colon cancer recurrence
    • Gerger A., Zhang W., Yang D., Bohanes P., Ning Y., Winder T., et al. Common cancer stem cell gene variants predict colon cancer recurrence. Clin. Cancer Res 2011, 17:6934-6943.
    • (2011) Clin. Cancer Res , vol.17 , pp. 6934-6943
    • Gerger, A.1    Zhang, W.2    Yang, D.3    Bohanes, P.4    Ning, Y.5    Winder, T.6
  • 7
    • 34548455927 scopus 로고    scopus 로고
    • Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer
    • Hermann P.C., Huber S.L., Herrler T., Aicher A., Ellwart J.W., Guba M., et al. Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer. Cell Stem Cell 2007, 1:313-323.
    • (2007) Cell Stem Cell , vol.1 , pp. 313-323
    • Hermann, P.C.1    Huber, S.L.2    Herrler, T.3    Aicher, A.4    Ellwart, J.W.5    Guba, M.6
  • 10
    • 71849118588 scopus 로고    scopus 로고
    • Comparative analysis of tumorbiology and CD133 positivity in primary and recurrent pancreatic ductal adenocarcinoma
    • Welsch T., Keleg S., Bergmann F., Degrate L., Bauer S., Schmidt J. Comparative analysis of tumorbiology and CD133 positivity in primary and recurrent pancreatic ductal adenocarcinoma. Clin. Exp. Metastasis 2009, 26:701-711.
    • (2009) Clin. Exp. Metastasis , vol.26 , pp. 701-711
    • Welsch, T.1    Keleg, S.2    Bergmann, F.3    Degrate, L.4    Bauer, S.5    Schmidt, J.6
  • 11
    • 84904246245 scopus 로고    scopus 로고
    • SOX2 controls tumour initiation and cancer stem-cell functions in squamous-cell carcinoma
    • Boumahdi S., Driessens G., Lapouge G., Rorive S., Nassar D., Le Mercier M., et al. SOX2 controls tumour initiation and cancer stem-cell functions in squamous-cell carcinoma. Nature 2014, 511(7508):246-250.
    • (2014) Nature , vol.511 , Issue.7508 , pp. 246-250
    • Boumahdi, S.1    Driessens, G.2    Lapouge, G.3    Rorive, S.4    Nassar, D.5    Le Mercier, M.6
  • 12
    • 84896514133 scopus 로고    scopus 로고
    • Sox2 is required to maintain cancer stem cells in a mouse model of high-grade oligodendroglioma
    • Favaro R., Appolloni I., Pellegatta S., Sanga A.B., Pagella P., Gambini E., et al. Sox2 is required to maintain cancer stem cells in a mouse model of high-grade oligodendroglioma. Cancer Res 2014, 74:1833-1844.
    • (2014) Cancer Res , vol.74 , pp. 1833-1844
    • Favaro, R.1    Appolloni, I.2    Pellegatta, S.3    Sanga, A.B.4    Pagella, P.5    Gambini, E.6
  • 13
  • 14
    • 33646865180 scopus 로고    scopus 로고
    • Control of developmental regulators by Polycomb in human embryonic stem cells
    • Lee T.I., Jenner R.G., Boyer L.A., Guenther M.G., Levine S.S., Kumar R.M., et al. Control of developmental regulators by Polycomb in human embryonic stem cells. Cell 2006, 125:301-313.
    • (2006) Cell , vol.125 , pp. 301-313
    • Lee, T.I.1    Jenner, R.G.2    Boyer, L.A.3    Guenther, M.G.4    Levine, S.S.5    Kumar, R.M.6
  • 16
    • 84866849548 scopus 로고    scopus 로고
    • Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer
    • Rudin C.M., Durinck S., Stawiski E.W., Poirier J.T., Modrusan Z., Shames D.S., et al. Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer. Nat. Genet 2012, 44:1111-1116.
    • (2012) Nat. Genet , vol.44 , pp. 1111-1116
    • Rudin, C.M.1    Durinck, S.2    Stawiski, E.W.3    Poirier, J.T.4    Modrusan, Z.5    Shames, D.S.6
  • 17
    • 33646051846 scopus 로고    scopus 로고
    • Histopathologic evaluation of stepwise progression of pancreatic carcinoma with immunohistochemical analysis of gastric epithelial transcription factor SOX2: comparison of expression patterns between invasive components and cancerous or nonneoplastic intraductal components
    • Sanada Y., Yoshida K., Ohara M., Oeda M., Konishi K., Tsutani Y. Histopathologic evaluation of stepwise progression of pancreatic carcinoma with immunohistochemical analysis of gastric epithelial transcription factor SOX2: comparison of expression patterns between invasive components and cancerous or nonneoplastic intraductal components. Pancreas 2006, 32:164-170.
    • (2006) Pancreas , vol.32 , pp. 164-170
    • Sanada, Y.1    Yoshida, K.2    Ohara, M.3    Oeda, M.4    Konishi, K.5    Tsutani, Y.6
  • 18
  • 19
    • 84875129324 scopus 로고    scopus 로고
    • Sox2 cooperates with inflammation-mediated Stat3 activation in the malignant transformation of foregut basal progenitor cells
    • Liu K., Jiang M., Lu Y., Chen H., Sun J., Wu S., et al. Sox2 cooperates with inflammation-mediated Stat3 activation in the malignant transformation of foregut basal progenitor cells. Cell Stem Cell 2013, 12:304-315.
    • (2013) Cell Stem Cell , vol.12 , pp. 304-315
    • Liu, K.1    Jiang, M.2    Lu, Y.3    Chen, H.4    Sun, J.5    Wu, S.6
  • 20
    • 44649117905 scopus 로고    scopus 로고
    • Integration of external signaling pathways with the core transcriptional network in embryonic stem cells
    • Chen X., Xu H., Yuan P., Fang F., Huss M., Vega V.B., et al. Integration of external signaling pathways with the core transcriptional network in embryonic stem cells. Cell 2008, 133:1106-1117.
    • (2008) Cell , vol.133 , pp. 1106-1117
    • Chen, X.1    Xu, H.2    Yuan, P.3    Fang, F.4    Huss, M.5    Vega, V.B.6
  • 21
    • 22744433845 scopus 로고    scopus 로고
    • The transcription factor Stat3 is dispensable for pancreatic beta-cell development and function
    • Lee J.Y., Hennighausen L. The transcription factor Stat3 is dispensable for pancreatic beta-cell development and function. Biochem. Biophys. Res. Commun 2005, 334:764-768.
    • (2005) Biochem. Biophys. Res. Commun , vol.334 , pp. 764-768
    • Lee, J.Y.1    Hennighausen, L.2
  • 22
    • 79953761842 scopus 로고    scopus 로고
    • Stat3 and MMP7 contribute to pancreatic ductal adenocarcinoma initiation and progression
    • Fukuda A., Wang S.C., Morris J.P., Folias A.E., Liou A., Kim G.E., et al. Stat3 and MMP7 contribute to pancreatic ductal adenocarcinoma initiation and progression. Cancer Cell 2011, 19:441-455.
    • (2011) Cancer Cell , vol.19 , pp. 441-455
    • Fukuda, A.1    Wang, S.C.2    Morris, J.P.3    Folias, A.E.4    Liou, A.5    Kim, G.E.6
  • 23
    • 0042825695 scopus 로고    scopus 로고
    • Activated signal transducer and activator of transcription 3 (STAT3) supports the malignant phenotype of human pancreatic cancer
    • Scholz A., Heinze S., Detjen K.M., Peters M., Welzel M., Hauff P., et al. Activated signal transducer and activator of transcription 3 (STAT3) supports the malignant phenotype of human pancreatic cancer. Gastroenterology 2003, 125:891-905.
    • (2003) Gastroenterology , vol.125 , pp. 891-905
    • Scholz, A.1    Heinze, S.2    Detjen, K.M.3    Peters, M.4    Welzel, M.5    Hauff, P.6
  • 24
    • 0037461934 scopus 로고    scopus 로고
    • Stat3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasis
    • Wei D., Le X., Zheng L., Wang L., Frey J.A., Gao A.C., et al. Stat3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasis. Oncogene 2003, 22:319-329.
    • (2003) Oncogene , vol.22 , pp. 319-329
    • Wei, D.1    Le, X.2    Zheng, L.3    Wang, L.4    Frey, J.A.5    Gao, A.C.6
  • 26
    • 84876132890 scopus 로고    scopus 로고
    • Activation of the IL-6R/Jak/stat pathway is associated with a poor outcome in resected pancreatic ductal adenocarcinoma
    • Denley S.M., Jamieson N.B., McCall P., Oien K.A., Morton J.P., Carter C.R., et al. Activation of the IL-6R/Jak/stat pathway is associated with a poor outcome in resected pancreatic ductal adenocarcinoma. J. Gastrointest. Surg 2013, 17:887-898.
    • (2013) J. Gastrointest. Surg , vol.17 , pp. 887-898
    • Denley, S.M.1    Jamieson, N.B.2    McCall, P.3    Oien, K.A.4    Morton, J.P.5    Carter, C.R.6
  • 27
    • 84899959071 scopus 로고    scopus 로고
    • Tumor-induced STAT3 activation in monocytic myeloid-derived suppressor cells enhances stemness and mesenchymal properties in human pancreatic cancer
    • Panni R.Z., Sanford D.E., Belt B.A., Mitchem J.B., Worley L.A., Goetz B.D., et al. Tumor-induced STAT3 activation in monocytic myeloid-derived suppressor cells enhances stemness and mesenchymal properties in human pancreatic cancer. Cancer Immunol. Immunother 2014, 63:513-528.
    • (2014) Cancer Immunol. Immunother , vol.63 , pp. 513-528
    • Panni, R.Z.1    Sanford, D.E.2    Belt, B.A.3    Mitchem, J.B.4    Worley, L.A.5    Goetz, B.D.6
  • 28
    • 70350212976 scopus 로고    scopus 로고
    • STAT3 is required for proliferation and maintenance of multipotency in glioblastoma stem cells
    • Sherry M.M., Reeves A., Wu J.K., Cochran B.H. STAT3 is required for proliferation and maintenance of multipotency in glioblastoma stem cells. Stem Cells 2009, 27:2383-2392.
    • (2009) Stem Cells , vol.27 , pp. 2383-2392
    • Sherry, M.M.1    Reeves, A.2    Wu, J.K.3    Cochran, B.H.4
  • 29
    • 79751473114 scopus 로고    scopus 로고
    • The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44
    • Liu C., Kelnar K., Liu B., Chen X., Calhoun-Davis T., Li H., et al. The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44. Nat. Med 2011, 17:211-215.
    • (2011) Nat. Med , vol.17 , pp. 211-215
    • Liu, C.1    Kelnar, K.2    Liu, B.3    Chen, X.4    Calhoun-Davis, T.5    Li, H.6
  • 30
    • 84878610693 scopus 로고    scopus 로고
    • MiR145 targets the SOX9/ADAM17 axis to inhibit tumor-initiating cells and IL-6-mediated paracrine effects in head and neck cancer
    • Yu C.C., Tsai L.L., Wang M.L., Yu C.H., Lo W.L., Chang Y.C., et al. miR145 targets the SOX9/ADAM17 axis to inhibit tumor-initiating cells and IL-6-mediated paracrine effects in head and neck cancer. Cancer Res 2013, 73:3425-3440.
    • (2013) Cancer Res , vol.73 , pp. 3425-3440
    • Yu, C.C.1    Tsai, L.L.2    Wang, M.L.3    Yu, C.H.4    Lo, W.L.5    Chang, Y.C.6
  • 31
    • 84879869302 scopus 로고    scopus 로고
    • Downregulation of miR-452 promotes stem-like traits and tumorigenicity of gliomas
    • Liu L., Chen K., Wu J., Shi L., Hu B., Cheng S., et al. Downregulation of miR-452 promotes stem-like traits and tumorigenicity of gliomas. Clin. Cancer Res 2013, 19:3429-3438.
    • (2013) Clin. Cancer Res , vol.19 , pp. 3429-3438
    • Liu, L.1    Chen, K.2    Wu, J.3    Shi, L.4    Hu, B.5    Cheng, S.6
  • 33
    • 77957255799 scopus 로고    scopus 로고
    • Transcriptional control of tight junction proteins via a protein kinase C signal pathway in human telomerase reverse transcriptase-transfected human pancreatic duct epithelial cells
    • Yamaguchi H., Kojima T., Ito T., Kimura Y., Imamura M., Son S., et al. Transcriptional control of tight junction proteins via a protein kinase C signal pathway in human telomerase reverse transcriptase-transfected human pancreatic duct epithelial cells. Am. J. Pathol 2010, 177:698-712.
    • (2010) Am. J. Pathol , vol.177 , pp. 698-712
    • Yamaguchi, H.1    Kojima, T.2    Ito, T.3    Kimura, Y.4    Imamura, M.5    Son, S.6
  • 34
    • 80755141289 scopus 로고    scopus 로고
    • Methylation of cancer-stem-cell-associated Wnt target genes predicts poor prognosis in colorectal cancer patients
    • de Sousa E.M.F., Colak S., Buikhuisen J., Koster J., Cameron K., de Jong J.H., et al. Methylation of cancer-stem-cell-associated Wnt target genes predicts poor prognosis in colorectal cancer patients. Cell Stem Cell 2011, 9:476-485.
    • (2011) Cell Stem Cell , vol.9 , pp. 476-485
    • de Sousa, E.M.F.1    Colak, S.2    Buikhuisen, J.3    Koster, J.4    Cameron, K.5    de Jong, J.H.6
  • 35
    • 53249113793 scopus 로고    scopus 로고
    • Pancreatic cancer stem cells: implications for the treatment of pancreatic cancer
    • Simeone D.M. Pancreatic cancer stem cells: implications for the treatment of pancreatic cancer. Clin. Cancer Res 2008, 14:5646-5648.
    • (2008) Clin. Cancer Res , vol.14 , pp. 5646-5648
    • Simeone, D.M.1
  • 36
    • 77950828177 scopus 로고    scopus 로고
    • MUC4 down-regulation reverses chemoresistance of pancreatic cancer stem/progenitor cells and their progenies
    • Mimeault M., Johansson S.L., Senapati S., Momi N., Chakraborty S., Batra S.K. MUC4 down-regulation reverses chemoresistance of pancreatic cancer stem/progenitor cells and their progenies. Cancer Lett 2010, 295:69-84.
    • (2010) Cancer Lett , vol.295 , pp. 69-84
    • Mimeault, M.1    Johansson, S.L.2    Senapati, S.3    Momi, N.4    Chakraborty, S.5    Batra, S.K.6
  • 37
    • 77954921889 scopus 로고    scopus 로고
    • Enhanced cell migration and invasion of CD133+ pancreatic cancer cells cocultured with pancreatic stromal cells
    • Moriyama T., Ohuchida K., Mizumoto K., Cui L., Ikenaga N., Sato N., et al. Enhanced cell migration and invasion of CD133+ pancreatic cancer cells cocultured with pancreatic stromal cells. Cancer 2010, 116:3357-3368.
    • (2010) Cancer , vol.116 , pp. 3357-3368
    • Moriyama, T.1    Ohuchida, K.2    Mizumoto, K.3    Cui, L.4    Ikenaga, N.5    Sato, N.6
  • 38
    • 79953756112 scopus 로고    scopus 로고
    • Stat3/Socs3 activation by IL-6 transsignaling promotes progression of pancreatic intraepithelial neoplasia and development of pancreatic cancer
    • Lesina M., Kurkowski M.U., Ludes K., Rose-John S., Treiber M., Kloppel G., et al. Stat3/Socs3 activation by IL-6 transsignaling promotes progression of pancreatic intraepithelial neoplasia and development of pancreatic cancer. Cancer Cell 2011, 19:456-469.
    • (2011) Cancer Cell , vol.19 , pp. 456-469
    • Lesina, M.1    Kurkowski, M.U.2    Ludes, K.3    Rose-John, S.4    Treiber, M.5    Kloppel, G.6
  • 39
    • 70350223977 scopus 로고    scopus 로고
    • Targeting interleukin 6 signaling suppresses glioma stem cell survival and tumor growth
    • Wang H., Lathia J.D., Wu Q., Wang J., Li Z., Heddleston J.M., et al. Targeting interleukin 6 signaling suppresses glioma stem cell survival and tumor growth. Stem Cells 2009, 27:2393-2404.
    • (2009) Stem Cells , vol.27 , pp. 2393-2404
    • Wang, H.1    Lathia, J.D.2    Wu, Q.3    Wang, J.4    Li, Z.5    Heddleston, J.M.6
  • 40
    • 84883635039 scopus 로고    scopus 로고
    • Inhibiting signal transducer and activator of transcription-3 increases response to gemcitabine and delays progression of pancreatic cancer
    • Venkatasubbarao K., Peterson L., Zhao S., Hill P., Cao L., Zhou Q., et al. Inhibiting signal transducer and activator of transcription-3 increases response to gemcitabine and delays progression of pancreatic cancer. Mol. Cancer 2013, 12:104.
    • (2013) Mol. Cancer , vol.12 , pp. 104
    • Venkatasubbarao, K.1    Peterson, L.2    Zhao, S.3    Hill, P.4    Cao, L.5    Zhou, Q.6
  • 41
    • 34247884391 scopus 로고    scopus 로고
    • Translating microRNA discovery into clinical biomarkers in cancer
    • Waldman S.A., Terzic A. Translating microRNA discovery into clinical biomarkers in cancer. JAMA 2007, 297:1923-1925.
    • (2007) JAMA , vol.297 , pp. 1923-1925
    • Waldman, S.A.1    Terzic, A.2
  • 42
    • 84861466680 scopus 로고    scopus 로고
    • MicroRNA profiling of a CD133(+) spheroid-forming subpopulation of the OVCAR3 human ovarian cancer cell line
    • Nam E.J., Lee M., Yim G.W., Kim J.H., Kim S., Kim S.W., et al. MicroRNA profiling of a CD133(+) spheroid-forming subpopulation of the OVCAR3 human ovarian cancer cell line. BMC Med. Genomics 2012, 5:18.
    • (2012) BMC Med. Genomics , vol.5 , pp. 18
    • Nam, E.J.1    Lee, M.2    Yim, G.W.3    Kim, J.H.4    Kim, S.5    Kim, S.W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.