Translating microRNA discovery into clinical biomarkers in cancer

JAMA

Volumn 297, Issue 17, 2007, Pages 1923-1925

  Waldman, Scott A ^a,c   Terzic, Andre ^b  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b MAYO CLINIC   (United States)

^c NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; DOUBLE STRANDED RNA; MICRORNA; TUMOR MARKER;

CANCER PREVENTION; CANCER SURVIVAL; CARCINOGENESIS; CHRONIC PANCREATITIS; CLINICAL PRACTICE; EDITORIAL; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE MAPPING; GENETIC EPIGENESIS; GENETIC TRANSCRIPTION; GENOMIC INSTABILITY; HUMAN; PANCREAS CANCER; PRIORITY JOURNAL; PROGNOSIS; TUMOR GROWTH; DNA MICROARRAY; GENETIC MARKER; GENETICS; NOTE; PANCREAS CARCINOMA; PANCREAS TUMOR;

CARCINOMA, PANCREATIC DUCTAL; GENETIC MARKERS; HUMANS; MICRORNAS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PANCREATIC NEOPLASMS;

EID: 34247884391     PISSN: 00987484     EISSN: 15383598     Source Type: Journal    
DOI: 10.1001/jama.297.17.1923     Document Type: Editorial

References (25)

1. American Cancer Society. Cancer statistics 2006. http://www.cancer.org. Accessibility verified April 9, 2007.
2. Dalton WS, Friend SH. Cancer biomarkers - an invitation to the table. Science. 2006;312:1165-1168.
3. Mathers CD, Loncar D. Projections of global mortality and burden of disease from 2002 to 2030. PLoS Med. 2006;3:e442.
4. Wilson C, Schulz S, Waldman SA. Biomarker development, commercialization, and regulation: individualization of medicine lost in translation. Clin Pharmacol Ther. 2007;81:153-155.
5. Wagner JA, Williams SA, Webster CJ. Biomarkers and surrogate end points for fit-for-purpose development and regulatory evaluation of new drugs. Clin Pharmacol Ther. 2007;81:104-107.
6. Calin GA, Croce CM. MicroRNA signatures in human cancers. Nat Rev Cancer. 2006;6:857-866.
7. Chen CZ. MicroRNAs as oncogenes and tumor suppressors. N Engl J Med. 2005;353:1768-1771.
8. Harfe BD. MicroRNAs in vertebrate development. Curr Opin Genet Dev. 2005;15:410-415.
9. Pasquinelli AE, Hunter S, Bracht J. MicroRNAs: a developing story. Curr Opin Genet Dev. 2005;15:200-205.
10. Bishop JM. Molecular themes in oncogenesis. Cell. 1991;64:235-248.
11. Weinberg RA. Tumor suppressor genes. Science. 1991;254:1138-1146.
12. Lu J, Getz G, Miska EA, et al. MicroRNA expression profiles classify human cancers. Nature. 2005;435:834-838.
13. Volinia S, Calin GA, Liu CG, et al. A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci U S A. 2006;103:2257-2261.
14. He H, Jazdzewski K, Li W, et al. The role of microRNA genes in papillary thyroid carcinoma. Proc Natl Acad Sci U S A. 2005;102:19075-19080.
15. Iorio MV, Ferracin M, Liu CG, et al. MicroRNA gene expression deregulation in human breast cancer. Cancer Res. 2005;65:7065-7070.
16. Murakami Y, Yasuda T, Saigo K, et al. Comprehensive analysis of microRNA expression patterns in hepatocellular carcinoma and non-tumorous tissues. Oncogene. 2006;25:2537-2545.
17. Roldo C, Missiaglia E, Hagan JP, et al. MicroRNA expression abnormalities in pancreatic endocrine and acinar tumors are associated with distinctive pathologic features and clinical behavior. J Clin Oncol. 2006;24:4677-4684.
18. Yanaihara N, Caplen N, Bowman E, et al. Unique microRNA molecular profiles in lung cancer diagnosis and prognosis. Cancer Cell. 2006;9:189-198.
19. Johnson SM, Grosshans H, Shingara J, et al. RAS is regulated by the let-7 microRNA family. Cell. 2005;120:635-647.
20. Bloomston M, Frankel WL, Petrocca F, et al. MicroRNA expression patterns to differentiate pancreatic adenocarcinoma from normal pancreas and chronic pancreatitis. JAMA. 2007;297:1901-1908.
21. Waldman SA, Christensen NB, Moore JE, Terzic A. Clinical pharmacology: the science of therapeutics. Clin Pharmacol Ther. 2007;81:3-6.
22. Wilson JF. The rocky road to useful cancer biomarkers. Ann Intern Med. 2006;144:945-948.
23. Hudson KL. Genetic testing oversight. Science. 2006;313:1853.
24. Liu CG, Calin GA, Meloon B, et al. An oligonucleotide microchip for genome-wide microRNA profiling in human and mouse tissues. Proc Natl Acad Sci U S A. 2004;101:9740-9744.
25. Williams SA, Slavin DE, Wagner JA, Webster CJ. A cost-effectiveness approach to the qualification and acceptance of biomarkers. Nat Rev Drug Discov. 2006;5:897-902.