-
1
-
-
32944469010
-
Changing paradigms - An update on the multidisciplinary management of malignant glioma
-
DOI 10.1634/theoncologist.11-2-165
-
Stupp R, Hegi ME, van den Bent MJ, Mason WP, Weller M, Mirimanoff RO, Cairncross JG (2006) Changing paradigms - an update on the multidisciplinary management of malignant glioma. Oncologist 11:165-180 (Pubitemid 43261763)
-
(2006)
Oncologist
, vol.11
, Issue.2
, pp. 165-180
-
-
Stupp, R.1
Hegi, M.E.2
Van Den, B.M.J.3
Mason, W.P.4
Weller, M.5
Mirimanoff, R.O.6
Cairncross, J.G.7
-
2
-
-
0037312920
-
IASPP oncoprotein is a key inhibitor of p53 conserved from worm to human
-
DOI 10.1038/ng1070
-
Bergamaschi D, Samuels Y, O'Neil NJ, Trigiante G, Crook T, Hsieh JK, O'Connor DJ, Zhong S, Campargue I, Tomlinson ML, Kuwabara PE, Lu X (2003) iASPP oncoprotein is a key inhibitor of p53 conserved from worm to human. Nat Genet 33:162-167 (Pubitemid 36177067)
-
(2003)
Nature Genetics
, vol.33
, Issue.2
, pp. 162-167
-
-
Bergamaschi, D.1
Samuels, Y.2
O'Neil, N.J.3
Trigiante, G.4
Crook, T.5
Hsieh, J.-K.6
O'Connor, D.J.7
Zhong, S.8
Campargue, I.9
Tomlinson, M.L.10
Kuwabara, P.E.11
Lu, X.12
-
3
-
-
0033575818
-
NF-kappaB subunit p65 binds to 53BP2 and inhibits cell death induced by 53BP2
-
DOI 10.1038/sj.onc.1202904
-
Yang JP, Hori M, Takahashi N, Kawabe T, Kato H, Okamoto T (1999) NF-kappaB subunit p65 binds to 53BP2 and inhibits cell death induced by 53BP2. Oncogene 18:5177-5186 (Pubitemid 29460653)
-
(1999)
Oncogene
, vol.18
, Issue.37
, pp. 5177-5186
-
-
Yang, J.-P.1
Hori, M.2
Takahashi, N.3
Kawabe, T.4
Kato, H.5
Okamoto, T.6
-
4
-
-
0033048966
-
Identification of a novel inhibitor of nuclear factor-kappaB, RelA-associated inhibitor
-
Yang JP, Hori M, Sanda T, Okamoto T (1999) Identification of a novel inhibitor of nuclear factor-kappaB, RelA-associated inhibitor. J Biol Chem 274:15662-15670
-
(1999)
J Biol Chem
, vol.274
, pp. 15662-15670
-
-
Yang, J.P.1
Hori, M.2
Sanda, T.3
Okamoto, T.4
-
5
-
-
33644555840
-
ASPPs and cancer
-
DOI 10.1038/nrc1818, PII N1818
-
Trigiante G, Lu X (2006) ASPPs and cancer. Nat Rev Cancer 6:217-226 (Pubitemid 43292565)
-
(2006)
Nature Reviews Cancer
, vol.6
, Issue.3
, pp. 217-226
-
-
Trigiante, G.1
Lu, X.2
-
6
-
-
0037418624
-
The ASPP family: Deciding between life and death after DNA damage
-
DOI 10.1016/S0378-4274(02)00421-6, PII S0378427402004216
-
Slee EA, Lu X (2003) The ASPP family: deciding between life and death after DNA damage. Toxicol Lett 139:81-87 (Pubitemid 36298965)
-
(2003)
Toxicology Letters
, vol.139
, Issue.2-3
, pp. 81-87
-
-
Slee, E.A.1
Lu, X.2
-
7
-
-
10644278820
-
The expression of iASPP in acute leukemias
-
DOI 10.1016/j.leukres.2004.07.001, PII S0145212604002450
-
Zhang X, Wang M, Zhou C, Chen S, Wang J (2005) The expression of iASPP in acute leukemias. Leuk Res 29:179-183 (Pubitemid 39647513)
-
(2005)
Leukemia Research
, vol.29
, Issue.2
, pp. 179-183
-
-
Zhang, X.1
Wang, M.2
Zhou, C.3
Chen, S.4
Wang, J.5
-
8
-
-
57049137197
-
Effect of RNA interference of iASPP on the apoptosis in MCF-7 breast cancer cells
-
Liu ZJ, Cai Y, Hou L, Gao X, Xin HM, Lu X, Zhong S, Gu SZ, Chen J (2008) Effect of RNA interference of iASPP on the apoptosis in MCF-7 breast cancer cells. Cancer Invest 26:878-882
-
(2008)
Cancer Invest
, vol.26
, pp. 878-882
-
-
Liu, Z.J.1
Cai, Y.2
Hou, L.3
Gao, X.4
Xin, H.M.5
Lu, X.6
Zhong, S.7
Gu, S.Z.8
Chen, J.9
-
9
-
-
0033970863
-
Aberrant overexpression of 53BP2 mRNA in lung cancer cell lines
-
DOI 10.1016/S0014-5793(99)01726-3, PII S0014579399017263
-
Mori T, Okamoto H, Takahashi N, Ueda R, Okamoto T (2000) Aberrant overexpression of 53BP2 mRNA in lung cancer cell lines. FEBS Lett 465:124-128 (Pubitemid 30021458)
-
(2000)
FEBS Letters
, vol.465
, Issue.2-3
, pp. 124-128
-
-
Mori, T.1
Okamoto, H.2
Takahashi, N.3
Ueda, R.4
Okamoto, T.5
-
10
-
-
85047689435
-
Potential applications of RNA interference technology in the treatment of cancer
-
Lage H (2005) Potential applications of RNA interference technology in the treatment of cancer. Future Oncol 1:103-113
-
(2005)
Future Oncol
, vol.1
, pp. 103-113
-
-
Lage, H.1
-
12
-
-
54249087596
-
RNAi-mediated silencing of nuclear factor erythroid-2-related factor 2 gene expression in non-small cell lung cancer inhibits tumor growth and increases efficacy of chemotherapy
-
Singh A, Boldin-Adamsky S, Thimmulappa RK, Rath SK, Ashush H, Coulter J, Blackford A, Goodman SN, Bunz F, Watson WH, Gabrielson E, Feinstein E, Biswal S (2008) RNAi-mediated silencing of nuclear factor erythroid-2-related factor 2 gene expression in non-small cell lung cancer inhibits tumor growth and increases efficacy of chemotherapy. Cancer Res 68:7975-7984
-
(2008)
Cancer Res
, vol.68
, pp. 7975-7984
-
-
Singh, A.1
Boldin-Adamsky, S.2
Thimmulappa, R.K.3
Rath, S.K.4
Ashush, H.5
Coulter, J.6
Blackford, A.7
Goodman, S.N.8
Bunz, F.9
Watson, W.H.10
Gabrielson, E.11
Feinstein, E.12
Biswal, S.13
-
13
-
-
0037134020
-
A system for stable expression of short interfering RNAs in mammalian cells
-
DOI 10.1126/science.1068999
-
Brummelkamp TR, Bernards R, Agami R (2002) A system for stable expression of short interfering RNAs in mammalian cells. Science 296:550-553 (Pubitemid 34408678)
-
(2002)
Science
, vol.296
, Issue.5567
, pp. 550-553
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
14
-
-
1642452660
-
Expression of small hairpin RNA by lentivirus-based vector confers efficient and stable gene-suppression of HIV-1 on human cells including primary non-dividing cells
-
DOI 10.1016/j.micinf.2003.10.009
-
Nishitsuji H, Ikeda T, Miyoshi H, Ohashi T, Kannagi M, Masuda T (2004) Expression of small hairpin RNA by lentivirus-based vector confers efficient and stable gene-suppression of HIV-1 on human cells including primary non-dividing cells. Microbes Infect 6:76-85 (Pubitemid 38114824)
-
(2004)
Microbes and Infection
, vol.6
, Issue.1
, pp. 76-85
-
-
Nishitsuji, H.1
Ikeda, T.2
Miyoshi, H.3
Ohashi, T.4
Kannagi, M.5
Masuda, T.6
-
15
-
-
0037370498
-
A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference
-
DOI 10.1038/ng1117
-
Rubinson DA, Dillon CP, Kwiatkowski AV, Sievers C, Yang L, Kopinja J, Rooney DL, Zhang M, Ihrig MM, McManus MT, Gertler FB, Scott ML, Van Parijs L (2003) A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference. Nat Genet 33:401-406 (Pubitemid 36278858)
-
(2003)
Nature Genetics
, vol.33
, Issue.3
, pp. 401-406
-
-
Rubinson, D.A.1
Dillon, C.P.2
Kwiatkowski, A.V.3
Sievers, C.4
Yang, L.5
Kopinja, J.6
Zhang, M.7
McManus, M.T.8
Gertler, F.B.9
Scott, M.L.10
Van Parijs, L.11
-
16
-
-
20844455902
-
Regulatory considerations for novel gene therapy products: A review of the process leading to the first clinical lentiviral vector
-
DOI 10.1089/hum.2005.16.17
-
Manilla P, Rebello T, Afable C, Lu X, Slepushkin V, Humeau LM, Schonely K, Ni Y, Binder GK, Levine BL, MacGregor RR, June CH, Dropulic B (2005) Regulatory considerations for novel gene therapy products: a review of the process leading to the first clinical lentiviral vector. Hum Gene Ther 16:17-25 (Pubitemid 40250328)
-
(2005)
Human Gene Therapy
, vol.16
, Issue.1
, pp. 17-25
-
-
Manilla, P.1
Rebello, T.2
Afable, C.3
Lu, X.4
Slepushkin, V.5
Humeau, L.M.6
Schonely, K.7
Ni, Y.8
Binder, G.K.9
Levine, B.L.10
Macgregor, R.-R.11
June, C.H.12
Dropulic, B.13
-
17
-
-
29744458522
-
A phase I/II clinical trial of beta-globin gene therapy for beta-thalassemia
-
DOI 10.1196/annals.1345.007
-
Bank A, Dorazio R, Leboulch P (2005) A phase I/II clinical trial of beta-globin gene therapy for beta-thalassemia. Ann N Y Acad Sci 1054:308-316 (Pubitemid 43031038)
-
(2005)
Annals of the New York Academy of Sciences
, vol.1054
, pp. 308-316
-
-
Bank, A.1
Dorazio, R.2
Leboulch, P.3
-
18
-
-
0344375083
-
Lentivirus-delivered stable gene silencing by RNAi in primary cells
-
DOI 10.1261/rna.2192803
-
Stewart SA, Dykxhoorn DM, Palliser D, Mizuno H, Yu EY, An DS, Sabatini DM, Chen IS, Hahn WC, Sharp PA, Weinberg RA, Novina CD (2003) Lentivirus-delivered stable gene silencing by RNAi in primary cells. RNA 9:493-501 (Pubitemid 36356735)
-
(2003)
RNA
, vol.9
, Issue.4
, pp. 493-501
-
-
Stewart, S.A.1
Dykxhoorn, D.M.2
Palliser, D.3
Mizuno, H.4
Yu, E.Y.5
An, D.S.6
Sabatini, D.M.7
Chen, I.S.Y.8
Hahn, W.C.9
Sharp, P.A.10
Weinberg, R.A.11
Novina, C.D.12
-
19
-
-
0035710746
-
-Delta Delta CT method
-
DOI 10.1006/meth.2001.1262
-
Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25:402-408 (Pubitemid 34164012)
-
(2001)
Methods
, vol.25
, Issue.4
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
20
-
-
0021061819
-
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
-
Mosmann T (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65:55-63
-
(1983)
J Immunol Methods
, vol.65
, pp. 55-63
-
-
Mosmann, T.1
-
21
-
-
0035477562
-
A flow cytometry assay simultaneously detects independent apoptotic parameters
-
DOI 10.1002/1097-0320(20011001)45:2<151::AID-CYTO1157>3.0.CO;2-I
-
Rasola A, Geuna M (2001) A flow cytometry assay simultaneously detects independent apoptotic parameters. Cytometry 45:151-157 (Pubitemid 32954245)
-
(2001)
Cytometry
, vol.45
, Issue.2
, pp. 151-157
-
-
Rasola, A.1
Geuna, M.2
-
23
-
-
0027983669
-
Crystal structure of a p53 tumor suppressor-DNA complex: Understanding tumorigenic mutations
-
Cho Y, Gorina S, Jeffrey PD, Pavletich NP (1994) Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations. Science 265:346-355 (Pubitemid 24259959)
-
(1994)
Science
, vol.265
, Issue.5170
, pp. 346-355
-
-
Cho, Y.1
Gorina, S.2
Jeffrey, P.D.3
Pavletich, N.P.4
-
24
-
-
10644232879
-
Abnormal mRNA expression of ASPP members in leukemia cell lines [6]
-
DOI 10.1038/sj.leu.2403300
-
Liu ZJ, Zhang Y, Zhang XB, Yang X (2004) Abnormal mRNA expression of ASPP members in leukemia cell lines. Leukemia 18:880 (Pubitemid 38500212)
-
(2004)
Leukemia
, vol.18
, Issue.4
, pp. 880
-
-
Liu, Z.-J.1
Zhang, Y.2
Zhang, X.-B.3
Yang, X.4
-
26
-
-
0027313366
-
A correlative study of p53 protein alteration and p53 gene mutation in glioblastoma multiforme
-
Newcomb EW, Madonia WJ, Pisharody S, Lang FF, Koslow M, Miller DC (1993) A correlative study of p53 protein alteration and p53 gene mutation in glioblastoma multiforme. Brain Pathol 3:229-235 (Pubitemid 23276689)
-
(1993)
Brain Pathology
, vol.3
, Issue.3
, pp. 229-235
-
-
Newcomb, E.W.1
Madonia, W.J.2
Pisharody, S.3
Lang, F.F.4
Koslow, M.5
Miller, D.C.6
-
27
-
-
0026517069
-
p53 mutations in human malignant gliomas: Comparison of loss of heterozygosity with mutation frequency
-
Frankel RH, Bayona W, Koslow M, Newcomb EW (1992) p53 mutations in human malignant gliomas: comparison of loss of heterozygosity with mutation frequency. Cancer Res 52:1427-1433
-
(1992)
Cancer Res
, vol.52
, pp. 1427-1433
-
-
Frankel, R.H.1
Bayona, W.2
Koslow, M.3
Newcomb, E.W.4
-
28
-
-
0028931265
-
Principles of CDK regulation
-
Morgan DO (1995) Principles of CDK regulation. Nature 374:131-134
-
(1995)
Nature
, vol.374
, pp. 131-134
-
-
Morgan, D.O.1
-
29
-
-
0031301882
-
p21: Structure and functions associated with cyclin-CDK binding
-
Ball KL (1997) p21: structure and functions associated with cyclin-CDK binding. Prog Cell Cycle Res 3:125-134
-
(1997)
Prog Cell Cycle Res
, vol.3
, pp. 125-134
-
-
Ball, K.L.1
-
30
-
-
0029103598
-
p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage
-
Macleod KF, Sherry N, Hannon G, Beach D, Tokino T, Kinzler K, Vogelstein B, Jacks T (1995) p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage. Genes Dev 9:935-944
-
(1995)
Genes Dev
, vol.9
, pp. 935-944
-
-
Macleod, K.F.1
Sherry, N.2
Hannon, G.3
Beach, D.4
Tokino, T.5
Kinzler, K.6
Vogelstein, B.7
Jacks, T.8
-
31
-
-
0028228907
-
Absence of cyclin D/cdk complexes in cells lacking functional retinoblastoma protein
-
Bates S, Parry D, Bonetta L, Vousden K, Dickson C, Peters G (1994) Absence of cyclin D/cdk complexes in cells lacking functional retinoblastoma protein. Oncogene 9:1633-1640 (Pubitemid 24163389)
-
(1994)
Oncogene
, vol.9
, Issue.6
, pp. 1633-1640
-
-
Bates, S.1
Parry, D.2
Bonetta, L.3
Vousden, K.4
Dickson, C.5
Peters, G.6
-
32
-
-
0028171292
-
G1 phase progression: Cycling on cue
-
Sherr CJ (1994) G1 phase progression: cycling on cue. Cell 79:551-555
-
(1994)
Cell
, vol.79
, pp. 551-555
-
-
Sherr, C.J.1
-
33
-
-
0028268284
-
D-type cyclin-dependent kinase activity in mammalian cells
-
Matsushime H, Quelle DE, Shurtleff SA, Shibuya M, Sherr CJ, Kato JY (1994) D-type cyclin-dependent kinase activity in mammalian cells. Mol Cell Biol 14:2066-2076 (Pubitemid 24074604)
-
(1994)
Molecular and Cellular Biology
, vol.14
, Issue.3
, pp. 2066-2076
-
-
Matsushime, H.1
Quelle, D.E.2
Shurtleff, S.A.3
Shibuya, M.4
Sherr, C.J.5
Kato, J.-Y.6
-
34
-
-
0026778547
-
Identification and properties of an atypical catalytic subunit (p34PSK-J3/cdk4) for mammalian D type G1 cyclins
-
Matsushime H, Ewen ME, Strom DK, Kato JY, Hanks SK, Roussel MF, Sherr CJ (1992) Identification and properties of an atypical catalytic subunit (p34PSK-J3/cdk4) for mammalian D type G1 cyclins. Cell 71:323-334
-
(1992)
Cell
, vol.71
, pp. 323-334
-
-
Matsushime, H.1
Ewen, M.E.2
Strom, D.K.3
Kato, J.Y.4
Hanks, S.K.5
Roussel, M.F.6
Sherr, C.J.7
|