Caffeine exposure alters cardiac gene expression in embryonic cardiomyocytes

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 307, Issue 12, 2014, Pages R1471-R1487

  Fang, Xiefan ^a   Mei, Wenbin ^b   Barbazuk, William B ^b   Rivkees, Scott A ^a   Wendler, Christopher C ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

Author keywords

Caffeine; Cardiac development; Cardiomyocyte; Differential exon usage; Differential gene expression

Indexed keywords

ADENOSINE RECEPTOR; ATRIAL NATRIURETIC FACTOR; BRAIN NATRIURETIC PEPTIDE; CAFFEINE; MICRORNA; MICRORNA 208A; MICRORNA 208B; MICRORNA 499; MYOSIN HEAVY CHAIN 7B CARDIAC MUSCLE; MYOSIN HEAVY CHAIN 7B CARDIAC MUSCLE BETA; MYOSIN HEAVY POLYPEPTIDE 6 CARDIAC MUSCLE ALPHA; NUCLEAR FACTOR OF ACTIVATED T CYTOPLASMIC CALCINEURIN DEPENDENT 3; PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA 4; TRANSCRIPTION FACTOR MEF2C; TRANSCRIPTION FACTOR MEF2D; TROPONIN I; TROPONIN I CARDIAC 3; TROPONIN T2 CARDIAC; UNCLASSIFIED DRUG; MESSENGER RNA;

ADULT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CD-1 MOUSE; CELL STRUCTURE; CELL VIABILITY; CIRCULATION; COMPARATIVE STUDY; CONTROLLED STUDY; DNA METHYLATION; EMBRYO CELL; FEMALE; GENE EXPRESSION; GENE IDENTIFICATION; HEART DEVELOPMENT; HEART FUNCTION; HEART MUSCLE CELL; HISTONE MODIFICATION; MOUSE; NONHUMAN; PRENATAL EXPOSURE; PROTEIN EXPRESSION; RNA SEQUENCE; STRUCTURAL GENE; ANIMAL; CARDIAC MUSCLE CELL; CELL CULTURE; CELL SHAPE; CELL SURVIVAL; DOSE RESPONSE; DRUG EFFECTS; EMBRYOLOGY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; GESTATIONAL AGE; HEART; MATERNAL EXPOSURE; METABOLISM; PATHOLOGY; PREGNANCY; TIME FACTOR;

ANIMALS; CAFFEINE; CELL SHAPE; CELL SURVIVAL; CELLS, CULTURED; DNA METHYLATION; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GESTATIONAL AGE; HEART; MATERNAL EXPOSURE; MICE; MICRORNAS; MYOCYTES, CARDIAC; PREGNANCY; RNA, MESSENGER; TIME FACTORS; TRANSCRIPTION FACTORS;

EID: 84919444250     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00307.2014     Document Type: Article

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