The synergetic effect of edaravone and borneol in the rat model of ischemic stroke

European Journal of Pharmacology

Volumn 740, Issue , 2014, Pages 522-531

  Wu, Hai Yin ^a   Tang, Ying ^a   Gao, Li Yan ^a   Sun, Wei Xiang ^a   Hua, Yao ^b   Yang, Shi Bao ^b   Zhang, Zheng Ping ^b   Liao, Gao Yong ^b   Zhou, Qi Gang ^a   Luo, Chun Xia ^a   Zhu, Dong Ya ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

^b Simcere Pharmaceuticals R and D   (China)

Author keywords

Anti inflammation; Borneol; Cerebral ischemia reperfusion; Edaravone; Free radical; Synergistic effect

Indexed keywords

BETA ACTIN; BORNEOL; CYCLOOXYGENASE 2; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; NORPHENAZONE; TUMOR NECROSIS FACTOR ALPHA; ANTIINFLAMMATORY AGENT; BORNANE DERIVATIVE; ISOBORNEOL; PHENAZONE; PHENYLMETHYLPYRAZOLONE; PTGS2 PROTEIN, RAT; SCAVENGER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BRAIN BLOOD FLOW; CONTROLLED STUDY; DRUG EFFICACY; DRUG POTENTIATION; EMBRYO; MIDDLE CEREBRAL ARTERY OCCLUSION; MORRIS WATER MAZE TEST; NONHUMAN; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; TRANSIENT ISCHEMIC ATTACK; ANALOGS AND DERIVATIVES; ANIMAL; BRAIN; BRAIN ISCHEMIA; CELL CULTURE; CELL SURVIVAL; COCULTURE; DISEASE MODEL; DRUG COMBINATION; DRUG EFFECTS; GLIA; MAZE TEST; METABOLISM; NERVE CELL; PATHOLOGY; SPRAGUE DAWLEY RAT; STROKE;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIPYRINE; BORNANES; BRAIN; BRAIN ISCHEMIA; CELL SURVIVAL; CELLS, CULTURED; COCULTURE TECHNIQUES; CYCLOOXYGENASE 2; DISEASE MODELS, ANIMAL; DRUG SYNERGISM; DRUG THERAPY, COMBINATION; FREE RADICAL SCAVENGERS; INTERLEUKIN-1BETA; MAZE LEARNING; NEUROGLIA; NEURONS; RATS, SPRAGUE-DAWLEY; STROKE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84919427232     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2014.06.035     Document Type: Article

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