Pyrrolidone carboxylic acid levels or caspase-14 expression in the corneocytes of lesional skin correlates with clinical severity, skin barrier function and lesional inflammation in atopic dermatitis

Journal of Dermatological Science

Volumn 76, Issue 3, 2014, Pages 231-239

  Jung, Minyoung ^a   Choi, Jaewoong ^a   Lee, Seon Ah ^b   Kim, Hyunjung ^b   Hwang, Joonsung ^c   Choi, Eung Ho ^a  

^a Yonsei University Wonju College of Medicine   (South Korea)

^b Seoul Medical Center   (South Korea)

^c Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

Author keywords

Atopic dermatitis; Caspase 14; Filaggrin; Natural moisturizing factor; Pyrrolidone carboxylic acid

Indexed keywords

CASPASE 14; FILAGGRIN; IMMUNOGLOBULIN E; INTERLEUKIN 13; INTERLEUKIN 1BETA; PYROGLUTAMIC ACID; TUMOR NECROSIS FACTOR ALPHA; CASP14 PROTEIN, HUMAN; CASPASE; INTERLEUKIN-13, HUMAN; INTERMEDIATE FILAMENT PROTEIN;

ADOLESCENT; ADULT; ARTICLE; ATOPIC DERMATITIS; CONTROLLED STUDY; CORNEOCYTE; CORRELATIONAL STUDY; CUTANEOUS PARAMETERS; DISEASE SEVERITY; ECZEMA; ENZYME LINKED IMMUNOSORBENT ASSAY; EPIDERMIS CELL; FEMALE; FLG GENE; GENE MUTATION; HUMAN; HYDRATION; IMMUNOGLOBULIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; PROTEIN BLOOD LEVEL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; SKIN BARRIER FUNCTION; SKIN SURFACE PH; SKIN WATER LOSS; STRATUM CORNEUM; TANDEM MASS SPECTROMETRY; X LINKED ICHTHYOSIS; CASE CONTROL STUDY; CHILD; EPIDERMIS; GENETICS; METABOLISM; MUTATION; PATHOLOGY; PRESCHOOL CHILD; YOUNG ADULT;

ADOLESCENT; ADULT; CASE-CONTROL STUDIES; CASPASES; CHILD; CHILD, PRESCHOOL; DERMATITIS, ATOPIC; EPIDERMIS; FEMALE; HUMANS; ICHTHYOSIS, X-LINKED; INTERLEUKIN-13; INTERLEUKIN-1BETA; INTERMEDIATE FILAMENT PROTEINS; MALE; MUTATION; PYRROLIDONECARBOXYLIC ACID; TUMOR NECROSIS FACTOR-ALPHA; YOUNG ADULT;

EID: 84919420604     PISSN: 09231811     EISSN: 1873569X     Source Type: Journal    
DOI: 10.1016/j.jdermsci.2014.09.004     Document Type: Article

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