PDLA/PLLA and PDLA/PCL nanofibers with a chitosan-based hydrogel in composite scaffolds for tissue engineered cartilage

Journal of Tissue Engineering and Regenerative Medicine

Volumn 8, Issue 12, 2014, Pages 946-954

  Wright, L D ^a   Mckeon Fischer, K D ^a   Cui, Z ^b   Nair, L S ^b,c   Freeman, J W ^a  

^a VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

^b UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^c UNIVERSITY OF CONNECTICUT   (United States)

Author keywords

Cartilage; Chitosan; Electrospinning; Hydrogel; Polyester; Scaffold; Tissue engineering

Indexed keywords

CARTILAGE; HYDROGELS; JOINTS (ANATOMY); SCAFFOLDS (BIOLOGY);

CARTILAGE TISSUE ENGINEERING; COMPOSITE SCAFFOLDS; ELECTROSPUNS; HYDROGEL SCAFFOLDS; L-LACTIDE; MUSCULOSKELETAL DISEASE; PLLA; POLY (L-LACTIDE); TISSUE ENGINEERED CARTILAGE; TISSUES ENGINEERINGS;

CHITOSAN;

CHITOSAN; COLLAGEN TYPE 2; NANOFIBER; POLYCAPROLACTONE; POLYLACTIDE; PROTEOGLYCAN; HYDROGEL; POLYMER;

ANIMAL CELL; ARTICLE; CARTILAGE; CHONDROCYTE; CONTROLLED STUDY; ELECTROSPINNING; EXTRACELLULAR MATRIX; HYDROGEL; IN VITRO STUDY; LEACHING; MECHANICAL STIMULUS TEST; NONHUMAN; OSTEOARTHRITIS; PROTEOGLYCAN SYNTHESIS; TISSUE ENGINEERING; TISSUE SCAFFOLD; CHEMISTRY; MATERIALS TESTING;

CARTILAGE; CHITOSAN; HYDROGELS; MATERIALS TESTING; NANOFIBERS; POLYMERS; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 84919398332     PISSN: 19326254     EISSN: 19327005     Source Type: Journal    
DOI: 10.1002/term.1591     Document Type: Article

References (22)

1. Berger J, Reist M, Mayer JM et al. 2004a; Structure and interactions in chitosan hydrogels formed by complexation or aggregation for biomedical applications. Eur J Pharm Biopharm 57(1): 35-52.
2. Berger J, Reist M, Mayer JM et al. 2004b; Structure and interactions in covalently and ionically crosslinked chitosan hydrogels for biomedical applications. Eur J Pharm Biopharm 57(1): 19-34.
3. Billington CJ. 2001; Cartilage proteoglycan release assay. Method Mol Biol (Clifton, N.J.) 151: 451-456.
4. Bonakdar S, Emami SH, Shokrgozar MA et al. 2010; Preparation and characterization of polyvinyl alcohol hydrogels crosslinked by biodegradable polyurethane for tissue engineering of cartilage. C-Mater Sci Eng-C 30(4): 636-643.
5. Buckwalter JA. 1998; Articular cartilage: injuries and potential for healing. J Orthop Sport Phys 28(4): 192-202.
6. Chen SC, Wu YC, Mi FL et al. 2004; A novel pH-sensitive hydrogel composed of N, O-carboxymethyl chitosan and alginate cross-linked by genipin for protein drug delivery. J Control Release 96(2): 285-300.
7. Cheung HY, Lau KT, Lu TP et al. 2007; A critical review on polymer-based bio-engineered materials for scaffold development. Compos Part B-Eng 38(3): 291-300.
8. Cowin SC. 2007; Tissue mechanics. New York, NY:, Springer.
9. Huang ZM, ZhangYZ, Kotaki M et al. 2003; A review on polymer nanofibers by electrospinning and their applications in nanocomposites. Compos Sci Technol 63(15): 2223-2253.
10. Huber M, Trattnig S, Lintner F. 2000; Anatomy, biochemistry, and physiology of articular cartilage. Invest Radiol 35(10): 573-580.
11. Khor E. 2001; Chitin: fulfilling a biomaterials promise. New York, Elsevier Science Ltd.
12. Kumar M. 2000; A review of chitin and chitosan applications. React Funct Polym 46(1): 1-27.
13. Lannutti J, Reneker D, Ma T et al. 2007; Electrospinning for tissue engineering scaffolds. C-Mater Sci Eng-C 27(3): 504-509.
14. Martins A, Reis RL, Neves NM. 2008; Electrospinning: processing technique for tissue engineering scaffolding. Int Mater Rev 53(5): 257-274.
15. Nair LS, Starnes T, Ko JW et al. 2007; Development of injectable thermogelling chitosan-inorganic phosphate solutions for biomedical applications. Biomacromolecules 8(12): 3779-3785.
16. Nam J, Huang Y, Agarwal S et al. 2007; Improved cellular infiltration in electrospun fiber via engineered porosity. Tissue Eng 13(9): 2249-2257.
17. Poole AR, Kojima T, Yasuda T et al. 2001; Composition and structure of articular cartilage - A template for tissue repair. Clin Orthop Relat R 391: S26-S33.
18. Shu XZ, Zhu KJ. 2000; A novel approach to prepare tripolyphosphate/chitosan complex beads for controlled release drug delivery. Int J Pharm 201(1): 51-58.
19. Slivka MA, Leatherbury NC, Kieswetter K et al. 2001; Porous, resorbable, fiber-reinforced scaffolds tailored for articular cartilage repair. Tissue Eng 7(6): 767-780.
20. Waldman SD, Spiteri CG, Grynpas MD et al. 2004; Long-term intermittent compressive stimulation improves the composition and mechanical properties of tissue-engineered cartilage. Tissue Eng 10(9-10): 1323-1331.
21. Wright LD, Andric T, Freeman JW. 2011; Utilizing NaCl to increase the porosity of electrospun materials. Mater Sci Eng C Mater Biol Appl 31(1): 30-36.
22. Wright LD, Young RT, Andric T et al. 2010; Fabrication and mechanical characterization of 3D electrospun scaffolds for tissue engineering. Biomed Mater 5(5): 055006.