Invitro exposure of haemocytes of the clam Ruditapes philippinarum to titanium dioxide (TiO2) nanoparticles: Nanoparticle characterisation, effects on phagocytic activity and internalisation of nanoparticles into haemocytes

Marine Environmental Research

Volumn 103, Issue , 2015, Pages 11-17

  Marisa, Ilaria ^a   Marin, Maria Gabriella ^a   Caicci, Federico ^a   Franceschinis, Erica ^a   Martucci, Alessandro ^a   Matozzo, Valerio ^a  

^a UNIVERSITY OF PADOVA   (Italy)

Author keywords

Bivalve; Haemocyte; Internalisation; Nanoparticles; Phagocytosis; Titanium dioxide; Transmission electron microscope

Indexed keywords

ANTIGEN-ANTIBODY REACTIONS; CYTOLOGY; MOLLUSCS; NANOPARTICLES; OXIDE MINERALS; SHELLFISH; TITANIUM DIOXIDE; TITANIUM METALLOGRAPHY; TRANSMISSION ELECTRON MICROSCOPY; TRANSMISSIONS;

AQUATIC ENVIRONMENTS; BIVALVE; HAEMOCYTE; INTERNALISATION; NANOPARTICLE CHARACTERISATION; PHAGOCYTOSIS; RUDITAPES PHILIPPINARUM; TITANIUM DIOXIDES (TIO2);

TIO2 NANOPARTICLES;

TITANIUM DIOXIDE; TITANIUM DIOXIDE NANOPARTICLE; METAL NANOPARTICLES; TITANIUM; WATER POLLUTANTS, CHEMICAL;

CYTOPLASM; MOLLUSC; NANOTECHNOLOGY; PHYSICOCHEMICAL PROPERTY; POLLUTION EFFECT; POLLUTION EXPOSURE; TITANIUM; TRANSMISSION ELECTRON MICROSCOPY;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIVALVE; BLOOD CELL; CELL FUNCTION; CELL INTERACTION; CELL MEMBRANE; CELL VACUOLE; CONTROLLED STUDY; CYTOPLASM; ELECTRON MICROSCOPY; EXPOSURE; HEMOLYMPH; IN VITRO STUDY; INTERNALIZATION; LASER DIFFRACTION; NANOANALYSIS; NONHUMAN; PARTICLE SIZE; PHAGOCYTOSIS; PHYSICAL CHEMISTRY; RUDITAPES PHILIPPINARUM; TRANSMISSION ELECTRON MICROSCOPY; X RAY DIFFRACTION; YEAST CELL; ANIMALS; BIVALVIA; DRUG EFFECTS; HEMOCYTES; MICROSCOPY, ELECTRON, TRANSMISSION; TOXICITY; WATER POLLUTANTS, CHEMICAL;

BIVALVIA; MOLLUSCA; VENERUPIS (RUDITAPES) PHILIPPINARUM;

ANIMALS; BIVALVIA; HEMOCYTES; METAL NANOPARTICLES; MICROSCOPY, ELECTRON, TRANSMISSION; PARTICLE SIZE; PHAGOCYTOSIS; TITANIUM; WATER POLLUTANTS, CHEMICAL;

EID: 84919394543     PISSN: 01411136     EISSN: 18790291     Source Type: Journal    
DOI: 10.1016/j.marenvres.2014.11.002     Document Type: Article

References (42)

1. Al-Subiai S.N., Arlt V.M., Frickers P.E., Readman J.W., Stolpe B., Lead J.R., Moody A.J., Jha A.N. Merging nano-genotoxicology with eco-genotoxicology: an integrated approach to determine interactive genotoxic and sub-lethal toxic effects of C60 fullerenes and fluoranthene in marine mussels, Mytilus sp. Mutat. Res. 2012, 745:92-103.
2. Ates M., Demir V., Adiguzel R., Arslan Z. Bioaccumulation, subacute toxicity, and tissue distribution of engineered titanium dioxide nanoparticles in Goldfish (Carassius auratus). J.Nanomater. 2013, 2013:6. Article ID 460518. 10.1155/2013/460518.
3. Baker T.J., Tyler C.R., Galloway T.S. Impacts of metal and metal oxide nanoparticles on marine organisms. Environ. Pollut. 2014, 186:257-271.
4. Ballarin L., Cima F., Sabbadin A. Phagocytosis in the colonial ascidian Botryllus schlosseri. Dev. Comp. Immunol. 1994, 18:467-481.
5. Baracco M.A., Medeiros I.D., Moreira F.M. Some haemato-immunological parameters in the mussel Perna perna. Fish Shellfish Immunol. 1999, 9:387-404.
6. 2 on digestive gland and immune function of the marine bivalve Mytilus galloprovincialis. Aquat. Toxicol. 2013, 132-133:9-18.
7. Bhatt I., Tripathi B.N. Interaction of engineered nanoparticles with various components of the environment and possible strategies for their risk assessment. Chemosphere 2011, 82:308-317.
8. Browne M.A., Dissanayake A., Galloway T.S., Lowe D.M., Thompson R.C. Ingested microscopic plastic translocates to the circulatory system of the mussel, Mytilus edulis (L). Environ. Sci. Technol. 2008, 42:5026-5031.
9. 2) on Mytilus hemocytes. Aquat. Toxicol. 2010, 96:151-158.
10. Canesi L., Ciacci C., Fabbri R., Marcomini A., Pojana G., Gallo G. Bivalve molluscs as a unique target group for nanoparticle toxicity. Mar. Environ. Res. 2012, 76:16-21.
11. 2 and 2,3,7,8-TCDD on the marine bivalve Mytilus galloprovincialis. Aquat. Toxicol. 2014, 153:53-65.
12. Chalew T.E.A., Galloway J.F., Graczyk T.K. Pilot study on effects of nanoparticle exposure on Crassostrea virginica hemocyte phagocytosis. Mar. Pollut. Bull. 2012, 64:2251-2253.
13. Ciacci C., Canonico B., Bilaniĉovă D., Fabbri R., Cortese K., Gallo G., Marcomini A., Pojana G., Canesi L. Immunomodulation by different types of n-oxides in the hemocytes of the marine bivalve Mytilus galloprovincialis. Plos One 2012, 7(5):e36937.
14. Cima F., Matozzo V., Marin M.G., Ballarin L. Haemocytes of the clam Tapes philippinarum (Adams & Reeve, 1850): morphofunctional characterisation. Fish Shellfish Immunol. 2000, 10:677-693.
15. Couleau N., Techer D., Pagnout C., Jomini S., Faocaud L., Laval-Gilly P., Falla J., Bennasroune A. Hemocyte responses of Dreissena polymorpha following a short-term invivo exposure to titanium dioxide nanoparticles: preliminary investigations. Sci. Total Environ. 2012, 438:490-497.
16. Donaghy L., Lambert C., Choi K., Soudant P. Hemocytes of the carpet shell clam (Ruditapes decussatus) and the Manila clam (Ruditapes philippinarum): current knowledge and future prospects. Aquaculture 2009, 297:10-24.
17. Frenzilli G., Bernardeschi M., Guidi P., Scarcelli V., Lucchesi P., Marsili L., Fossi M.C., Brunelli A., Pojana G., Marcomini A., Nigro Effects of invitro exposure to titanium dioxide on DNA integrity of bottlenose dolphin (Tursiops truncatus) fibroblasts and leukocytes. Mar. Environ. Res. 2014, 100:68-73.
18. Galloway T.S., Depledge M.H. Immunotoxicity in invertebrates: measurement and ecotoxicological relevance. Ecotoxicology 2001, 10:5-23.
19. Garćia-Negrete C.A., Blasco J., Volland M., Rojas T.C., Hampel M., Lapresta-Fernández, Jimenénez de Haro M.C., Soto M., Fernández A. Behaviour of Au-citrate nanoparticles in seawater and accumulation in bivalves at environmentally relevant concentrations. Environ. Pollut. 2013, 174:134-141.
20. Grimaldi A.M., Belcari P., Pagano E., Cacialli F., Locatello L. Immune responses of Octopus vulgaris (Mollusca: Cephalopoda) exposed to titanium dioxide nanoparticles. J.Exp. Mar. Biol. Ecol. 2013, 447:123-127.
21. Handy R.D., Owen R., Valsami-Jones E. The ecotoxicology of nanoparticles and nanomaterials: current status, knowledge gaps, challenges, and future needs. Ecotoxicology 2008, 17:315-325.
22. Jacobasch C., Völker C., Giebner S., Völker J., Alsenz H., Potouridis T., Heidenreich H., Kayser G., Oehlmann J., Oetken M. Long-term effects of nanoscaled titanium dioxide on the cladoceran Daphnia magna over six generations. Environ. Pollut. 2014, 186:180-186.
23. Jovanović B. Critical review of public health regulations of titanium dioxide, a human food additive. Integr. Environ. Assess. Manag. 2014, (in press). 10.1002/ieam.1571.
24. Jovanović B., Palić D. Immunotoxicology of non-functionalized engineered nanoparticles in aquatic organisms with special emphasis on fish - review of current knowledge, gap identification, and call for further research. Aquat. Toxicol. 2012, 118-119:141-151.
25. Kumar C. Nanotechnologies for the Life Sciences 2006, vol. 5. Wiley-VHC, Weinheim. first ed.
26. Matozzo V. Effects of pharmaceuticals on immune parameters of aquatic invertebrates. Invertebrate Surviv. J. 2014, 11:163-173.
27. Matozzo V., Rova G., Marin M.G. Haemocytes of the cockle Cerastoderma glaucum: morphological characterisation and involvement in immune responses. Fish Shellfish Immunol. 2007, 23:732-746.
28. Matranga V., Corsi I. Toxic effects of engineered nanoparticles in the marine environment: model organisms and molecular approaches. Mar. Environ. Res. 2012, 76:32-40.
29. 2. Review of invivo data. Environ. Pollut. 2011, 159:677-684.
30. Moore M.N. Do nanoparticles present ecotoxicological risks for the health of the aquatic environment?. Environ. Int. 2006, 32:967-976.
31. Nel A., Xia T., Madler L., Li N. Toxic potential of materials at the nanolevel. Science 2006, 311:622-627.
32. Olabarrieta I., L'Azou B., Yuric S., Cambar J., Cajaraville M.P. Invitro effects of cadmium on two different animal cell models. Toxicol. Vitro 2001, 15:511-517.
33. Pipe R.K., Coles J.A. Environmental contaminants influencing immune function in marine bivalve molluscs. Fish Shellfish Immunol. 1995, 5:581-595.
34. Rana S., Kalaichelvan P.T. Ecotoxicity of nanoparticles. ISRN Toxicol. 2013, 2013:11.
35. 2) nanoparticle-induced cytotoxicity and oxidative DNA damage in fish cells. Mutat. Res. 2008, 640:113-122.
36. 2 production as a basis for exposure assessment. Environ. Sci. Technol. 2009, 43:4227-4233.
37. Scown T.M., Aerle R.V., Tyler C.R. Review: do engineered nanoparticles pose a significant threat to the aquatic environment?. Crit. Rev. Toxicol. 2010, 40:653-670.
38. Takahashi K.G., Muroga K. Cellular defense mechanisms in bivalve molluscs. Fish Pathol. 2008, 43:1-17.
39. USEPA Nanomaterial Case Studies: Nanoscale Titanium Dioxide in Water Treatment and in Topical Sunscreen 2009, United States Environmental Protection Agency, Washington, DC, EPA/600/R-09/057.
40. 2 under hypoxia in the green-lipped mussel Perna viridis based on flow cytometric analysis of hemocyte parameters. Sci. Total Environ. 2014, 470-471:791-799.
41. Wootton E.C., Dyrynda E.A., Ratcliffe N.A. Bivalve immunity: comparisons between the marine mussel (Mytilus edulis), the edible cockle (Cerastoderma edule) and the razor-shell (Ensis siliqua). Fish Shellfish Immunol. 2003, 15:195-210.
42. Wokovich A., Tyner K., Doub W., Sadrieh N., Buhse L.F. Particle size determination of sunscreens formulated with various forms of titanium dioxide. Drug Dev. Ind. Pharm. 2009, 35:1180-1189.