PCB 126 perturbs hypoxia-induced HIF-1α activity and glucose consumption in human HepG2 cells

Experimental and Toxicologic Pathology

Volumn 66, Issue 8, 2014, Pages 377-382

  Vorrink, Sabine U ^a,b   Sarsour, Ehab H ^b   Olivier, Alicia K ^b   Robertson, Larry W ^a   Goswami, Prabhat C ^a,b   Domann, Frederick E ^a,b  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

Cellular metabolism; Hepatocytes; Low oxygen environments; Nuclear localization; Polychlorinated biphenyls

Indexed keywords

3,3',4,4',5 PENTACHLOROBIPHENYL; GLUCOSE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; 3,4,5,3',4'-PENTACHLOROBIPHENYL; ANTIESTROGEN; AROMATIC HYDROCARBON RECEPTOR; POLYCHLORINATED BIPHENYL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL HYPOXIA; CELL METABOLISM; CELL NUCLEUS; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VIVO STUDY; LIVER CELL; MALE; NONHUMAN; PROTEIN LOCALIZATION; RAT; SIGNAL TRANSDUCTION; ANIMAL; DRUG EFFECTS; ENERGY METABOLISM; HEPG2 CELL LINE; IMMUNOHISTOCHEMISTRY; METABOLISM; PHYSIOLOGY; WESTERN BLOTTING;

RATTUS;

ANIMALS; BLOTTING, WESTERN; CELL HYPOXIA; ENERGY METABOLISM; ESTROGEN ANTAGONISTS; GLUCOSE; HEP G2 CELLS; HEPATOCYTES; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMMUNOHISTOCHEMISTRY; POLYCHLORINATED BIPHENYLS; RATS; RECEPTORS, ARYL HYDROCARBON;

EID: 84919393306     PISSN: 09402993     EISSN: 16181433     Source Type: Journal    
DOI: 10.1016/j.etp.2014.05.005     Document Type: Article

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