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1
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70349513258
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Emerging role of glutamate in the pathophysiology of major depressive disorder
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Hashimoto K (2009) Emerging role of glutamate in the pathophysiology of major depressive disorder. Brain Res Rev 61:105-123
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(2009)
Brain Res Rev
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Hashimoto, K.1
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R-Stereoisomer of ketamine as alternative of ketamine for treatment-resistant major depression
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Hashimoto K (2014a) R-Stereoisomer of ketamine as alternative of ketamine for treatment-resistant major depression. Clin Psychopharmacol Neurosci 12:72-73
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(2014)
Clin Psychopharmacol Neurosci
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Hashimoto, K.1
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Targeting of NMDA receptors in the new treatment of schizophrenia
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Hashimoto K (2014b) Targeting of NMDA receptors in the new treatment of schizophrenia. Expert Opin Ther Targets 18:1049-1063
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(2014)
Expert Opin Ther Targets
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Hashimoto, K.1
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4
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0037977113
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Decreased serum levels of D-serine in patients with schizophrenia. Evidence in support of the N-methyl-D-aspartate receptor hypofunction hypothesis of schizophrenia
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Hashimoto K, Fukushima T, Shimizu E, Komatsu N, Watanabe H, Shinoda N, Nakazato M, Kumakiri C, Okada S, Hasegawa H, Imai K, Iyo M (2003) Decreased serum levels of D-serine in patients with schizophrenia. Evidence in support of the N-methyl-D-aspartate receptor hypofunction hypothesis of schizophrenia. Arch Gen Psychiatry 60:572-576
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Hashimoto, K.1
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Watanabe, H.5
Shinoda, N.6
Nakazato, M.7
Kumakiri, C.8
Okada, S.9
Hasegawa, H.10
Imai, K.11
Iyo, M.12
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5
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84881313914
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Glutamate modulators as potential therapeutic drugs in schizophrenia and affective disorders
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Hashimoto K, Malchow B, Falkai P, Schmitt A (2013) Glutamate modulators as potential therapeutic drugs in schizophrenia and affective disorders. Eur Arch Psychiatry Clin Neurosci 263:367-377
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(2013)
Eur Arch Psychiatry Clin Neurosci
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Hashimoto, K.1
Malchow, B.2
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Schmitt, A.4
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6
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35848939420
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Increased levels of glutamate in brains from patients with mood disorders
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Hashimoto K, Sawa A, Iyo M (2007) Increased levels of glutamate in brains from patients with mood disorders. Biol Psychiatry 62:1310-1316
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(2007)
Biol Psychiatry
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Hashimoto, K.1
Sawa, A.2
Iyo, M.3
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7
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40849106310
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Roles of L-serine and sphingolipid synthesis in brain development and neuronal survival
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Hirabayashi Y, Furuya S (2008) Roles of L-serine and sphingolipid synthesis in brain development and neuronal survival. Prog Lipid Res 47:188-203
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Prog Lipid Res
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Hirabayashi, Y.1
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Rapid-acting glutamatergic antidepressants: The path to ketamine and beyond
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Krystal JH, Sanacora G, Duman RS (2013) Rapid-acting glutamatergic antidepressants: the path to ketamine and beyond. Biol Psychiatry 73:1133-1141
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Biol Psychiatry
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Krystal, J.H.1
Sanacora, G.2
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9
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78649990339
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Analyses of mechanism for mouse strain-dependent prepulse inhibition point to a role of Shmt1 (SHMT1) in mice and schizophrenia
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Maekawa T, Ohnishi T, Hashimoto K, Watanabe A, Iwayama Y, Ohba H, Hattori E, Yamada K, Yoshikawa T (2010) Analyses of mechanism for mouse strain-dependent prepulse inhibition point to a role of Shmt1 (SHMT1) in mice and schizophrenia. J Neurochem 115: 1374-1385
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(2010)
J Neurochem
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Maekawa, T.1
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Hattori, E.7
Yamada, K.8
Yoshikawa, T.9
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10
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85027908160
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D-serine plasma concentration is a potential biomarker of (R,S)-ketamine antidepressant response in subjects with major depressive disorder
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in press
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Moaddel R, Luckenbaugh DA, Xie Y, Villasenor A, Brutsche NE, Machado-Vieira R, Ramamoorthy A, Lorenzo MP, Carcia A, Bernier M, Torjman MC, Barbas C, Zarate CA, Wainer JW (2014) D-serine plasma concentration is a potential biomarker of (R,S)-ketamine antidepressant response in subjects with major depressive disorder. Psychopharmacology in press
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(2014)
Psychopharmacology
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Moaddel, R.1
Luckenbaugh, D.A.2
Xie, Y.3
Villasenor, A.4
Brutsche, N.E.5
Machado-Vieira, R.6
Ramamoorthy, A.7
Lorenzo, M.P.8
Carcia, A.9
Bernier, M.10
Torjman, M.C.11
Barbas, C.12
Zarate, C.A.13
Wainer, J.W.14
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11
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20444406392
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Identification of multiple serine racemase (SRR) mRNA isoforms and genetic analyses of SRR and DAO in schizophrenia and D-serine levels
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Yamada K, Ohnishi T, Hashimoto K, Ohba H, Iwayama-Shigeno Y, Takao H, Toyota T, Minabe Y, Nakamura K, Shimizu E, Itokawa M, Mori N, Iyo M, Yoshikawa T (2005) Identification of multiple serine racemase (SRR) mRNA isoforms and genetic analyses of SRR and DAO in schizophrenia and D-serine levels. Biol Psychiatry 57:1493-1503
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(2005)
Biol Psychiatry
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Yamada, K.1
Ohnishi, T.2
Hashimoto, K.3
Ohba, H.4
Iwayama-Shigeno, Y.5
Takao, H.6
Toyota, T.7
Minabe, Y.8
Nakamura, K.9
Shimizu, E.10
Itokawa, M.11
Mori, N.12
Iyo, M.13
Yoshikawa, T.14
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12
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84899618176
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Rapid antidepressant effects and abuse liability of ketamine
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Yang C, Hashimoto K (2014) Rapid antidepressant effects and abuse liability of ketamine. Psychopharmacology 231:2041-2042
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(2014)
Psychopharmacology
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Yang, C.1
Hashimoto, K.2
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13
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84864286398
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Relationship of ketamine's plasma metabolites with response, diagnosis, and side effects in major depression
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Zarate CA Jr, Brutsche N, Laje G, Luckenbaugh DA, Venkata SLV, Ramamoorthy A, Moaddel R, Wainer IW (2012) Relationship of ketamine's plasma metabolites with response, diagnosis, and side effects in major depression. Biol Psychiatry 72:331-338
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Biol Psychiatry
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Zarate, C.A.1
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Venkata, S.L.V.5
Ramamoorthy, A.6
Moaddel, R.7
Wainer, I.W.8
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14
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84889953872
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R (-)-ketamine shows greater potency and longer lasting antidepressant effects than S (+)-ketamine
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Zhang JC, Li SX, Hashimoto K (2014) R (-)-ketamine shows greater potency and longer lasting antidepressant effects than S (+)-ketamine. Pharmacol Biochem Behav 116:137-141
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(2014)
Pharmacol Biochem Behav
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Zhang, J.C.1
Li, S.X.2
Hashimoto, K.3
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