Gene expression in relation to exhaled nitric oxide identifies novel asthma phenotypes with unique biomolecular pathways

American Journal of Respiratory and Critical Care Medicine

Volumn 190, Issue 12, 2014, Pages 1363-1372

  Modena, Brian D ^a   Tedrow, John R ^a   Milosevic, Jadranka ^a   Bleecker, Eugene R ^b   Meyers, Deborah A ^b   Wu, Wei ^c   Bar Joseph, Ziv ^c   Erzurum, Serpil C ^d   Gaston, Benjamin M ^e   Busse, William W ^f   Jarjour, Nizar N ^f   Kaminski, Naftali ^g   Wenzel, Sally E ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b WAKE FOREST SCHOOL OF MEDICINE   (United States)

^c Carnegie Mellon University   (United States)

^d LERNER RESEARCH INSTITUTE   (United States)

^e CASE WESTERN RESERVE UNIVERSITY   (United States)

^f UNIVERSITY OF WISCONSIN MADISON   (United States)

^g YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Clustering; Exhaled nitric oxide; Severe asthma

Indexed keywords

BIOLOGICAL MARKER; NITRIC OXIDE;

ACTIN FILAMENT; ADULT; ARTICLE; ASTHMA; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DISEASE SEVERITY; EPITHELIUM CELL; FEMALE; FRACTIONAL EXHALED NITRIC OXIDE; GENE CLUSTER; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; MAJOR CLINICAL STUDY; MALE; MICROARRAY ANALYSIS; MIDDLE AGED; NERVE FUNCTION; OBSERVATIONAL STUDY; PHENOTYPE; RESPIRATORY TRACT PARAMETERS; SIGNAL TRANSDUCTION; WNT SIGNALING PATHWAY; BRONCHUS; CASE CONTROL STUDY; CYTOLOGY; DNA MICROARRAY; GENETICS; METABOLISM; MULTIGENE FAMILY; REAL TIME POLYMERASE CHAIN REACTION;

ADULT; ASTHMA; BIOMARKERS; BRONCHI; CASE-CONTROL STUDIES; FEMALE; GENE EXPRESSION; HUMANS; MALE; MIDDLE AGED; MULTIGENE FAMILY; NITRIC OXIDE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHENOTYPE; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 84919363553     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201406-1099OC     Document Type: Article

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