Diterpenes from Euphorbia piscatoria: Synergistic interaction of lathyranes with doxorubicin on resistant cancer cells

Planta Medica

Volumn 80, Issue 18, 2014, Pages 1739-1745

  Reis, Mariana A ^a   Paterna, Angela ^a   Mónico, Andreia ^a   Molnar, Joseph ^b   Lage, Hermann ^c   Ferreira, Maria José U ^a  

^a UNIVERSITY OF LISBON   (Portugal)

^b UNIVERSITY OF SZEGED   (Hungary)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

abietane lactones; Euphorbia piscatoria; Euphorbiaceae; lathyrane macrocyclic diterpenes; MDR reversal

Indexed keywords

15 ACETOXY 5,6 EPOXYLATHYR 12 EN 3BETA OL 14 ONE; DITERPENE; DOXORUBICIN; ENT 13 HYDROXY 3,14 DIOXO 16 ATISENE; EUPHORBIA EXTRACT; HELIOSCOPINOLIDE E; LACTONE DERIVATIVE; LATHYRANE DERIVATIVE; PISCATOLIDE; PISCATORIC ACID; PISCATORIOL A; PISCATORIOL B; UNCLASSIFIED DRUG; ABCB1 PROTEIN, HUMAN; ANTINEOPLASTIC AGENT; LATHYRANE; MULTIDRUG RESISTANCE PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; ASSAY; BIOSYNTHESIS; CANCER CELL; CANCER CELL LINE; CARBON NUCLEAR MAGNETIC RESONANCE; COLON CANCER CELL LINE; CONTROLLED STUDY; CORRELATION SPECTROSCOPY; DISTORTIONLESS ENHANCEMENT BY POLARIZATION TRANSFER; DRUG ISOLATION; DRUG POTENTIATION; DRUG STRUCTURE; EUPHORBIA; EUPHORBIA PISCATORIA; GASTRIC CANCER CELL LINE; GENE; HETERONUCLEAR MULTIPLE BOND CORRELATION; HETERONUCLEAR MULTIPLE QUANTUM COHERENCE; LYMPHOMA CELL LINE; MOUSE; MULTIDRUG RESISTANCE PROTEIN 1 GENE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; NUCLEAR OVERHAUSER EFFECT; ONE DIMENSIONAL NUCLEAR MAGNETIC RESONANCE; PANCREATIC CANCER CELL LINE; PROTON NUCLEAR MAGNETIC RESONANCE; SPECTROSCOPY; TWO DIMENSIONAL NUCLEAR MAGNETIC RESONANCE; ANIMAL; CELL PROLIFERATION; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; DRUG RESISTANCE; DRUG SCREENING; GENETICS; LYMPHOMA; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; TUMOR CELL LINE;

EUPHORBIA; EUPHORBIA PISCATORIA; EUPHORBIACEAE;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CELL LINE, TUMOR; CELL PROLIFERATION; DITERPENES; DOXORUBICIN; DRUG RESISTANCE, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; EUPHORBIA; LYMPHOMA; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MOLECULAR STRUCTURE; P-GLYCOPROTEINS;

EID: 84919354129     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0034-1383244     Document Type: Article

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