Clinical and imaging features associated with an increased risk of late stroke in patients with asymptomatic carotid disease

European Journal of Vascular and Endovascular Surgery

Volumn 48, Issue 6, 2014, Pages 633-640

  Naylor, A R ^a   Schroeder, T V ^b   Sillesen, H ^b  

^a LEICESTER ROYAL INFIRMARY   (United Kingdom)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Carotid stenosis; Endarterectomy; Stenting; Stroke; Transient ischemic attack

Indexed keywords

BIOLOGICAL MARKER;

ALGORITHM; ARTIFICIAL EMBOLISM; ATHEROSCLEROTIC PLAQUE; CARDIOVASCULAR RISK; CAROTID ARTERY DISEASE; CAROTID ARTERY STENTING; CAROTID ENDARTERECTOMY; CEREBROVASCULAR ACCIDENT; CLINICAL FEATURE; CLINICAL TRIAL; COMPUTER ASSISTED TOMOGRAPHY; DIAGNOSTIC IMAGING; DISEASE COURSE; HEART INFARCTION; HUMAN; MEDICAL SOCIETY; NUCLEAR MAGNETIC RESONANCE IMAGING; PRACTICE GUIDELINE; REVIEW; RISK FACTOR; SCORING SYSTEM; SILENT MYOCARDIAL INFARCTION; STENOSIS; ANGIOPLASTY; ASYMPTOMATIC DISEASE; CAROTID STENOSIS; COMPLICATION; DEVICES; PATIENT SELECTION; PREDICTIVE VALUE; PROCEDURES; PROGNOSIS; RISK ASSESSMENT; SEVERITY OF ILLNESS INDEX; STENT; STROKE;

ANGIOPLASTY; ASYMPTOMATIC DISEASES; CAROTID STENOSIS; DIAGNOSTIC IMAGING; ENDARTERECTOMY, CAROTID; HUMANS; PATIENT SELECTION; PREDICTIVE VALUE OF TESTS; PROGNOSIS; RISK ASSESSMENT; RISK FACTORS; SEVERITY OF ILLNESS INDEX; STENTS; STROKE;

EID: 84919345227     PISSN: 10785884     EISSN: 15322165     Source Type: Journal    
DOI: 10.1016/j.ejvs.2014.08.017     Document Type: Review

References (36)

1. L.B. Goldstein, C.D. Bushnell, R.J. Adams, L.J. Appel, L.T. Braun, and S. Chaturvedi Guidelines for the primary prevention of stroke. A guideline for healthcare professionals from the American Heart Association/American Stroke Association Stroke 42 2011 517 584
2. B.K. Nallamothu, M. Lu, M.A.M. Rogers, H.S. Gurm, and J.D. Birkmeyer Physician specialty and carotid stenting among elderly Medicare beneficiaries in the United States Arch Intern Med 171 2011 1804 1810
3. C. Daly, and H.E. Rodriguez Carotid artery occlusive disease Surg Clin North Am 93 2013 813 832
4. Executive Committee for the Asymptomatic Carotid Atherosclerosis Study Endarterectomy for asymptomatic carotid artery stenosis JAMA 273 1995 1421 1428
5. Asymptomatic Carotid Surgery Trial Collaborators The MRC Asymptomatic Carotid Surgery Trial (ACST): carotid endarterectomy prevents disabling and fatal carotid territory strokes Lancet 363 2004 1491 1502
6. A. Halliday, M. Harrison, E. Hayter, X. Kong, A. Mansfield, and J. Maro 10 year stroke prevention after successful carotid endarterectomy for asymptomatic carotid stenosis (ACST-1): a multicentre randomised trial Lancet 376 2010 1074 1084
7. A.R. Naylor, P.A. Gaines, and P.M. Rothwell Who benefits most from intervention for asymptomatic carotid stenosis: patients of professional? Eur J Vasc Endovasc Surg 37 2009 625 632
8. A.R. Naylor Time to rethink management strategies in asymptomatic carotid disease Nat Rev Cardiol 9 2011 116 124
9. J.A. Beckman Management of asymptomatic carotid stenosis JAMA 310 2013 1612 1618
10. A.R. Naylor, P.M. Rothwell, and P.R.F. Bell Overview of the principal results and secondary analyses from the European and North American randomised trials of endarterectomy for symptomatic carotid stenosis Eur J Vasc Endovasc Surg 26 2003 115 129
11. A.N. Nicolaides, S.K. Kakkos, M. Griffin, M. Sabetai, S. Dhanjil, and T. Tegos Severity of asymptomatic carotid stenosis and risk of ipsilateral hemispheric ischaemic events: results from ACSRS Eur J Vasc Endovasc Surg 30 2005 275 284
12. L.S. Hirt Progression rate and ipsilateral neurological events in asymptomatic carotid stenosis Stroke 45 2014 702 706
13. S. Sabetai, O. Schlager, M. Exner, W. Mlekusch, J. Amighi, and P. Dick Progression of carotid stenosis detected by Duplex ultrasonography predicts adverse outcomes in cardiovascular high risk patients Stroke 38 2007 2887 2894
14. S.K. Kakkos, A.N. Nicolaides, I. Charalambous, D. Thomas, A. Giannopoulos, and A.R. Naylor Predictors and clinical significance of progression or regression of asymptomatic carotid stenosis J Vasc Surg 59 2014 956 967
15. A.G. Den Hartog, A.W. Halliday, E. Hayter, H. Pan, X. Kong, F.L. Moll on behalf of the Asymptomatic Carotid Surgery Trial Collaborators Stroke 44 2013 1652 1659
16. E.B. Mathiesen, K.H. Bonaa, and O. Joakimsen Echolucent plaques are associated with high risk of ischemic cerebrovascular events in carotid stenosis: the Tromso Study Circulation 103 2001 2171 2175
17. J.F. Polak, L. Shemanski, and D.H. O'Leary Hypoechoic plaque at US of the carotid artery: an independent risk factor for incident stroke in adults aged 65 years or older. Cardiovascular Health Study Radiology 208 1998 649 654
18. W.T. Longstreth, L. Shemanski, D. Lefkowitz, D.H. O'Leary, J.F. Polak, and S.K. Wolfson Asymptomatic internal carotid artery stenosis defined by ultrasound and the risk of subsequent stroke in the elderly: the Cardiovascular Health Study Stroke 29 1998 2371 2376
19. R. Topakian, A. King, U. Kwon, A. Schaafsma, M. Shipley, and H. Markus Ultrasonic plaque echolucency and emboli signals predict stroke in asymptomatic carotid stenosis Neurology 77 2011 751 758
20. A. Nicolaides, S.K. Kakkos, E. Kyriacou, M. Griffin, D.J. Thomas, and G. Geroulakos Asymptomatic internal carotid artery stenosis and cerebrovascular risk stratification J Vasc Surg 52 2010 1486 1496
21. M.-L. Gronholdt, B.G. Nordestgaard, T.V. Schroeder, S. Vorstrup, and H. Sillesen Ultrasonic echolucent carotid plaques predict future strokes Circulation 104 2001 68 73
22. G. Geroulakos, G. Ramaswami, A.N. Nicolaides, K. James, N. Labropoulos, and G. Belcaro Characterization of symptomatic and asymptomatic carotid plaques using high-resolution, real-time ultrasonography Br J Surg 80 1993 1274 1277
23. M.K. Salem, M.J. Bown, R.D. Sayers, K. West, D. Moore, and A. Nicolaides Identification of patients with a histologically unstable carotid plaque using ultrasonic plaque image analysis Eur J Vasc Endovasc Surg 48 2014 118 125
24. A. Kitamura, H. Iso, H. Imano, T. Ohira, T. Okada, and S. Sato Carotid intima-media thickness and plaque characteristics as a risk factor for stroke in Japanese elderly men Stroke 35 2004 2788 2794
25. S. Prabhakaran, T. Rundek, R. Ramas, M.S.V. Elkind, C.P. Myunghee, and B. Boden-Albala Carotid plaque surface irregularity predicts ischemic stroke: the Northern Manhattan Study Stroke 37 2006 2696 2701
26. A. Madani, V. Beletsky, A. Tamayo, C. Munoz, and J.D. Spence High-risk asymptomatic carotid stenosis ulceration on 3D ultrasound vs TCD microemboli Neurology 77 2011 744 750
27. H.R. Underhill, C. Yuan, V.L. Yarnykh, B. Chu, M. Oikawa, and L. Dong Predictors of surface disruption with MRI in asymptomatic carotid artery stenosis Am J Neuroradiol 31 2010 487 493
28. L. Esposito-Bauer, T. Saam, I. Ghodrati, J. Pelisek, P. Heider, and M. Bauer MRI plaque imaging detects carotid plaques with a high risk for future cerebrovascular events in asymptomatic patients PLoS One 8 7 2013 e67927
29. N. Takaya, C. Yuan, B. Chu, T. Saam, H. Underhill, and J. Cai Association between carotid plaque characteristics and subsequent ischaemic cerebrovascular events: a prospective assessment with MRI - initial results Stroke 37 2006 818 823
30. N. Singh, A.R. Moody, D.J. Gladstone, G. Leung, R. Ravikumar, and J. Zhan Moderate carotid artery stenosis: MR imaging depicted intraplaque haemorrhage predicts risk of cerebrovascular ischaemic events in asymptomatic men Radiology 252 2009 502 508
31. N. Altaf, L. Daniels, P.S. Morgan, D. Auer, S.T. MacSweeney, and A.R. Moody Detection of intraplaque hemorrhage by magnetic resonance imaging in symptomatic patients with mild to moderate carotid stenosis predicts recurrent neurological events J Vasc Surg 47 2008 337 342
32. H.S. Markus, A. King, M. Shipley, R. Topakian, M. Cullinane, and S. Reihill Asymptomatic embolisation for prediction of stroke in the asymptomatic carotid emboli study: a prospective observational study Lancet Neurol 9 2010 663 671
33. D.J. Spence, V. Coates, H. Li, A. Tamayo, C. Munoz, and D.G. Hackam Effects of intensive medical therapy on microemboli and cardiovascular risk in asymptomatic carotid stenosis Arch Neurol 67 2010 180 186
34. S.K. Kakkos, M. Sabetai, T. Tegos, J. Stevens, D. Thomas, and M. Griffin Silent embolic infarcts on computed tomography brain scans and risk of ipsilateral hemispheric events in patients with asymptomatic internal carotid artery stenosis J Vasc Surg 49 2009 902 909
35. ACST-2 Collaborators. Prior symptoms or brain infarcts will identify higher risk patients with "asymptomatic" stenosis. Retrieved February 20 2014 from: https://vascularsociety.eventhq.co.uk/files/31/Programme%20and%20abstract%20book%20-20%final.pdf
36. G. Sarlon-Bartoli, A. Boudes, C. Buffat, M.A. Bartoli, M.D. Piercecchi-Marti, and E. Sarlon Circulating lipoprotein-associated phospholipase a2 in high-grade carotid stenosis: a new biomarker for predicting unstable plaque Eur J Vasc Endovasc Surg 43 2012 154 159