CTGF/CCN2 exerts profibrotic action in myoblasts via the up-regulation of sphingosine kinase-1/S1P3 signaling axis: Implications in the action mechanism of TGFβ

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1851, Issue 2, 2015, Pages 194-202

  Bruno, Gennaro ^a   Cencetti, Francesca ^a,b   Pertici, Irene ^a   Japtok, Lukasz ^c   Bernacchioni, Caterina ^a,b   Donati, Chiara ^a,b   Bruni, Paola ^a,b  

^a UNIVERSITY OF FLORENCE   (Italy)

^b Istituto Interuniversitario di Miologia   (Italy)

^c UNIVERSITY OF POTSDAM   (Germany)

Author keywords

Connective tissue growth factor; Myoblasts; S1P3 receptor; Sphingosine kinase; Transforming growth factor beta

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CONNECTIVE TISSUE GROWTH FACTOR; MESSENGER RNA; SPHINGOSINE 1 PHOSPHATE RECEPTOR; SPHINGOSINE KINASE 1; TRANSFORMING GROWTH FACTOR BETA; TRANSGELIN; CTGF PROTEIN, MOUSE; EDG3 PROTEIN, MOUSE; PHOSPHOTRANSFERASE; RECOMBINANT PROTEIN; SPHINGOSINE KINASE; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ARTICLE; CELL FUNCTION; CELL TRANSDIFFERENTIATION; DOWN REGULATION; GENE SILENCING; IMMEDIATE EARLY GENE; MOUSE; MYOBLAST; NONHUMAN; PROTEIN CONTENT; PROTEIN EXPRESSION; PROTEIN METABOLISM; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SECOND CERVICAL VERTEBRA; SIGNAL TRANSDUCTION; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; UPREGULATION; WESTERN BLOTTING; ANIMAL; CELL LINE; DOSE RESPONSE; DRUG EFFECTS; ENZYMOLOGY; FIBROSIS; GENETIC TRANSFECTION; GENETICS; METABOLISM; MYOFIBROBLAST; PATHOLOGY; RNA INTERFERENCE; TIME;

ANIMALS; CELL LINE; CELL TRANSDIFFERENTIATION; CONNECTIVE TISSUE GROWTH FACTOR; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBROSIS; MICE; MYOBLASTS, SKELETAL; MYOFIBROBLASTS; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); RECEPTORS, LYSOSPHINGOLIPID; RECOMBINANT PROTEINS; RNA INTERFERENCE; RNA, MESSENGER; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA1; UP-REGULATION;

EID: 84919338270     PISSN: 13881981     EISSN: 18792618     Source Type: Journal    
DOI: 10.1016/j.bbalip.2014.11.011     Document Type: Article

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