-
1
-
-
75749111389
-
New frontiers in gut nutrient sensor research: prophylactic effect of glutamine against Helicobacter pylori-induced gastric diseases in Mongolian gerbils
-
Amagase, K., Nakamura, E., Endo, T., Hayashi, S., Hasumura, M., Uneyama, H., etal. (2010) New frontiers in gut nutrient sensor research: prophylactic effect of glutamine against Helicobacter pylori-induced gastric diseases in Mongolian gerbils. J Pharmacol Sci 112: 25-32.
-
(2010)
J Pharmacol Sci
, vol.112
, pp. 25-32
-
-
Amagase, K.1
Nakamura, E.2
Endo, T.3
Hayashi, S.4
Hasumura, M.5
Uneyama, H.6
-
2
-
-
0020617998
-
Glutamine metabolism in lymphocytes of the rat
-
Ardawi, M.S., and Newsholme, E.A. (1983) Glutamine metabolism in lymphocytes of the rat. Biochem J 212: 835-842.
-
(1983)
Biochem J
, vol.212
, pp. 835-842
-
-
Ardawi, M.S.1
Newsholme, E.A.2
-
3
-
-
0031888904
-
Lymphocytes in the human gastric mucosa during Helicobacter pylori have a T helper cell 1 phenotype
-
Bamford, K.B., Fan, X., Crowe, S.E., Leary, J.F., Gourley, W.K., Luthra, G.K., etal. (1998) Lymphocytes in the human gastric mucosa during Helicobacter pylori have a T helper cell 1 phenotype. Gastroenterology 114: 482-492.
-
(1998)
Gastroenterology
, vol.114
, pp. 482-492
-
-
Bamford, K.B.1
Fan, X.2
Crowe, S.E.3
Leary, J.F.4
Gourley, W.K.5
Luthra, G.K.6
-
4
-
-
0018628604
-
High concentrations of glutathione in glandular stomach: possible implications for carcinogenesis
-
Body, S.C., Sasame, H.A., and Body, M.R. (1979) High concentrations of glutathione in glandular stomach: possible implications for carcinogenesis. Science 205: 1010-1012.
-
(1979)
Science
, vol.205
, pp. 1010-1012
-
-
Body, S.C.1
Sasame, H.A.2
Body, M.R.3
-
5
-
-
9144220868
-
The Helicobacter pylori vacuolating toxin inhibits T cell activation by two independent mechanisms
-
Boncristiano, M., Paccani, S.R., Barone, S., Ulivieri, C., Patrussi, L., Ilver, D., etal. (2003) The Helicobacter pylori vacuolating toxin inhibits T cell activation by two independent mechanisms. J Exp Med 198: 1887-1897.
-
(2003)
J Exp Med
, vol.198
, pp. 1887-1897
-
-
Boncristiano, M.1
Paccani, S.R.2
Barone, S.3
Ulivieri, C.4
Patrussi, L.5
Ilver, D.6
-
6
-
-
77955475969
-
Glutamine uptake and metabolism are coordinately regulated by ERK/MAPK during T lymphocyte activation
-
Carr, E.L., Kelman, A., Wu, G.S., Gopaul, R., Senkevitch, E., Aghvanyan, A., etal. (2010) Glutamine uptake and metabolism are coordinately regulated by ERK/MAPK during T lymphocyte activation. J Immunol 185: 1037-1044.
-
(2010)
J Immunol
, vol.185
, pp. 1037-1044
-
-
Carr, E.L.1
Kelman, A.2
Wu, G.S.3
Gopaul, R.4
Senkevitch, E.5
Aghvanyan, A.6
-
7
-
-
0036051315
-
Glutamine protects activated human T cells from apoptosis by up-regulating glutathione and Bcl-2 levels
-
Chang, W.-K., Yang, K.D., Chuang, H., Jan, J.-T., and Shaio, M.-F. (2002) Glutamine protects activated human T cells from apoptosis by up-regulating glutathione and Bcl-2 levels. Clin Immunol 104: 151-160.
-
(2002)
Clin Immunol
, vol.104
, pp. 151-160
-
-
Chang, W.-K.1
Yang, K.D.2
Chuang, H.3
Jan, J.-T.4
Shaio, M.-F.5
-
8
-
-
0032982703
-
Essential role of Helicobacter pylori gamma-glutamyltranspeptidase for the colonization of the gastric mucosa of mice
-
Chevalier, C., Thiberge, J.M., Ferrero, R.L., and Labigne, A. (1999) Essential role of Helicobacter pylori gamma-glutamyltranspeptidase for the colonization of the gastric mucosa of mice. Mol Microbiol 31: 1359-1372.
-
(1999)
Mol Microbiol
, vol.31
, pp. 1359-1372
-
-
Chevalier, C.1
Thiberge, J.M.2
Ferrero, R.L.3
Labigne, A.4
-
9
-
-
67650553603
-
mTOR: taking cues from the immune microenvironment
-
Delgoffe, G.M., and Powell, J.D. (2009) mTOR: taking cues from the immune microenvironment. Immunology 127: 459-465.
-
(2009)
Immunology
, vol.127
, pp. 459-465
-
-
Delgoffe, G.M.1
Powell, J.D.2
-
10
-
-
66949173728
-
The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment
-
Delgoffe, G.M., Kole, T.P., Zheng, Y., Zarek, P.E., Matthews, K.L., Xiao, B., etal. (2009) The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment. Immunity 30: 832-844.
-
(2009)
Immunity
, vol.30
, pp. 832-844
-
-
Delgoffe, G.M.1
Kole, T.P.2
Zheng, Y.3
Zarek, P.E.4
Matthews, K.L.5
Xiao, B.6
-
11
-
-
0031567981
-
T helper 1 effector cells specific for Helicobacter pylori in the gastric antrum of patients with peptic ulcer disease
-
D'Elios, M.M., Manghetti, M., De Carli, M., Costa, F., Baldari, C.T., Burroni, D., etal. (1997) T helper 1 effector cells specific for Helicobacter pylori in the gastric antrum of patients with peptic ulcer disease. J Immunol 158: 962-967.
-
(1997)
J Immunol
, vol.158
, pp. 962-967
-
-
D'Elios, M.M.1
Manghetti, M.2
De Carli, M.3
Costa, F.4
Baldari, C.T.5
Burroni, D.6
-
12
-
-
81355146607
-
Gastric epithelial cell death caused by Helicobacter suis and Helicobacter pylori gamma-glutamyl transpeptidase is mainly glutathione degradation-dependent
-
Flahou, B., Haesebrouck, F., Chiers, K., Van Deun, K., De Smet, L., Devreese, B., etal. (2011) Gastric epithelial cell death caused by Helicobacter suis and Helicobacter pylori gamma-glutamyl transpeptidase is mainly glutathione degradation-dependent. Cell Microbiol 13: 1933-1955.
-
(2011)
Cell Microbiol
, vol.13
, pp. 1933-1955
-
-
Flahou, B.1
Haesebrouck, F.2
Chiers, K.3
Van Deun, K.4
De Smet, L.5
Devreese, B.6
-
13
-
-
0028208969
-
Ligation of the T cell receptor complex results in activation of the Ras/Raf-1/MEK/MAPK cascade in human T lymphocytes
-
Franklin, R.A., Tordai, A., Patel, H., Gardner, A.M., Johnson, G.L., and Gelfand, E.W. (1994) Ligation of the T cell receptor complex results in activation of the Ras/Raf-1/MEK/MAPK cascade in human T lymphocytes. J Clin Invest 93: 2134-2140.
-
(1994)
J Clin Invest
, vol.93
, pp. 2134-2140
-
-
Franklin, R.A.1
Tordai, A.2
Patel, H.3
Gardner, A.M.4
Johnson, G.L.5
Gelfand, E.W.6
-
14
-
-
78650826181
-
Tissue distribution of 5-hydroxymethylcytosine and search for active demethylation intermediates
-
Globisch, D., Munzel, M., Muller, M., Michalakis, S., Wagner, M., Koch, S., etal. (2010) Tissue distribution of 5-hydroxymethylcytosine and search for active demethylation intermediates. PLoS ONE 5: e15367.
-
(2010)
PLoS ONE
, vol.5
, pp. e15367
-
-
Globisch, D.1
Munzel, M.2
Muller, M.3
Michalakis, S.4
Wagner, M.5
Koch, S.6
-
15
-
-
65349083718
-
Inflammation and foveolar hyperplasia are reduced by supplemental dietary glutamine during Helicobacter pylori infection in mice
-
Hagen, S.J., Ohtani, M., Zhou, J.-R., Taylor, N.S., Rickman, B.H., Blackburn, G.L., and Fox, J.G. (2009) Inflammation and foveolar hyperplasia are reduced by supplemental dietary glutamine during Helicobacter pylori infection in mice. J Nutr 139: 912-918.
-
(2009)
J Nutr
, vol.139
, pp. 912-918
-
-
Hagen, S.J.1
Ohtani, M.2
Zhou, J.-R.3
Taylor, N.S.4
Rickman, B.H.5
Blackburn, G.L.6
Fox, J.G.7
-
16
-
-
3843111219
-
Evidence for cyclin D3 as a novel target of rapamycin in human T lymphocytes
-
Hleb, M., Murphy, S., Wagner, E.F., Hanna, N.N., Sharma, N., Park, J., etal. (2004) Evidence for cyclin D3 as a novel target of rapamycin in human T lymphocytes. J Biol Chem 279: 31948-31955.
-
(2004)
J Biol Chem
, vol.279
, pp. 31948-31955
-
-
Hleb, M.1
Murphy, S.2
Wagner, E.F.3
Hanna, N.N.4
Sharma, N.5
Park, J.6
-
17
-
-
0027770941
-
Exogenous glutamine requirement is confined to late events of T cell activation
-
Horig, H., Spagnoli, G.C., Filgueira, L., Babst, R., Gallati, H., Harder, F., etal. (1993) Exogenous glutamine requirement is confined to late events of T cell activation. J Cell Biochem 53: 343-351.
-
(1993)
J Cell Biochem
, vol.53
, pp. 343-351
-
-
Horig, H.1
Spagnoli, G.C.2
Filgueira, L.3
Babst, R.4
Gallati, H.5
Harder, F.6
-
18
-
-
84858959572
-
Distinct roles of secreted HtrA proteases from gram-negative pathogens in cleaving the junctional protein and tumor suppressor E-cadherin
-
Hoy, B., Geppert, T., Boehm, M., Reisen, F., Plattner, P., Gadermaier, G., etal. (2012) Distinct roles of secreted HtrA proteases from gram-negative pathogens in cleaving the junctional protein and tumor suppressor E-cadherin. J Biol Chem 287: 10115-10120.
-
(2012)
J Biol Chem
, vol.287
, pp. 10115-10120
-
-
Hoy, B.1
Geppert, T.2
Boehm, M.3
Reisen, F.4
Plattner, P.5
Gadermaier, G.6
-
19
-
-
84891080042
-
Helicobacter pylori cytotoxin-associated gene A impairs human dendritic cell maturation and function through IL-10-mediated activation of STAT3
-
Kaebisch, R., Mejias-Luque, R., Prinz, C., and Gerhard, M. (2014) Helicobacter pylori cytotoxin-associated gene A impairs human dendritic cell maturation and function through IL-10-mediated activation of STAT3. J Immunol 192: 316-323.
-
(2014)
J Immunol
, vol.192
, pp. 316-323
-
-
Kaebisch, R.1
Mejias-Luque, R.2
Prinz, C.3
Gerhard, M.4
-
20
-
-
35748956420
-
Rapamycin inhibits differentiation of Th17 cells and promotes generation of FoxP3+ T regulatory cells
-
Kopf, H., de la Rosa, G.M., Howard, O.M.Z., and Chen, X. (2007) Rapamycin inhibits differentiation of Th17 cells and promotes generation of FoxP3+ T regulatory cells. Int Immunopharmacol 7: 1819-1824.
-
(2007)
Int Immunopharmacol
, vol.7
, pp. 1819-1824
-
-
Kopf, H.1
de la Rosa, G.M.2
Howard, O.M.Z.3
Chen, X.4
-
21
-
-
0034326645
-
Up-regulation of IL-17 is associated with bioactive IL-8 expression in Helicobacter pylori-infected human gastric mucosa
-
Luzza, F., Parrello, T., Monteleone, G., Sebkova, L., Romano, M., Zarrilli, R., etal. (2000) Up-regulation of IL-17 is associated with bioactive IL-8 expression in Helicobacter pylori-infected human gastric mucosa. J Immunol 165: 5332-5337.
-
(2000)
J Immunol
, vol.165
, pp. 5332-5337
-
-
Luzza, F.1
Parrello, T.2
Monteleone, G.3
Sebkova, L.4
Romano, M.5
Zarrilli, R.6
-
22
-
-
0035017794
-
Gamma-glutamyltransferase is a Helicobacter pylori virulence factor but is not essential for colonization
-
McGovern, K.J., Blanchard, T.G., Gutierrez, J.A., Czinn, S.J., Krakowka, S., and Youngman, P. (2001) Gamma-glutamyltransferase is a Helicobacter pylori virulence factor but is not essential for colonization. Infect Immun 69: 4168-4173.
-
(2001)
Infect Immun
, vol.69
, pp. 4168-4173
-
-
McGovern, K.J.1
Blanchard, T.G.2
Gutierrez, J.A.3
Czinn, S.J.4
Krakowka, S.5
Youngman, P.6
-
23
-
-
84886720433
-
The transcription factor IRF4 is essential for TCR affinity-mediated metabolic programming and clonal expansion of T cells
-
Man, K., Miasari, M., Shi, W., Xin, A., Henstridge, D.C., Preston, S., etal. (2013) The transcription factor IRF4 is essential for TCR affinity-mediated metabolic programming and clonal expansion of T cells. Nat Immunol 14: 1155-1165.
-
(2013)
Nat Immunol
, vol.14
, pp. 1155-1165
-
-
Man, K.1
Miasari, M.2
Shi, W.3
Xin, A.4
Henstridge, D.C.5
Preston, S.6
-
24
-
-
0022196860
-
Glutamine metabolism in lymphocytes: its biochemical, physiological and clinical importance
-
Newsholme, E.A., Crabtree, B., and Ardawi, M.S. (1985) Glutamine metabolism in lymphocytes: its biochemical, physiological and clinical importance. Q J Exp Physiol 70: 473-489.
-
(1985)
Q J Exp Physiol
, vol.70
, pp. 473-489
-
-
Newsholme, E.A.1
Crabtree, B.2
Ardawi, M.S.3
-
25
-
-
84874251522
-
Helicobacter pylori gamma-glutamyl transpeptidase and vacuolating cytotoxin promote gastric persistence and immune tolerance
-
Oertli, M., Noben, M., Engler, D.B., Semper, R.P., Reuter, S., Maxeiner, J., etal. (2013) Helicobacter pylori gamma-glutamyl transpeptidase and vacuolating cytotoxin promote gastric persistence and immune tolerance. Proc Natl Acad Sci USA 110: 3047-3052.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 3047-3052
-
-
Oertli, M.1
Noben, M.2
Engler, D.B.3
Semper, R.P.4
Reuter, S.5
Maxeiner, J.6
-
26
-
-
0035674232
-
Eradication of Helicobacter pylori restores glutathione S-transferase activity and glutathione levels in antral mucosa
-
Oijen, A.H., Verhulst, M.L., Roelofs, H.M., Peters, W.H., de Boer, W.A., and Jansen, J.B. (2001) Eradication of Helicobacter pylori restores glutathione S-transferase activity and glutathione levels in antral mucosa. Jpn J Cancer Res 92: 1329-1334.
-
(2001)
Jpn J Cancer Res
, vol.92
, pp. 1329-1334
-
-
Oijen, A.H.1
Verhulst, M.L.2
Roelofs, H.M.3
Peters, W.H.4
de Boer, W.A.5
Jansen, J.B.6
-
27
-
-
0033104824
-
Inhibition of cell cycle progression by rapamycin induces T cell clonal anergy even in the presence of costimulation
-
Powell, J.D., Lerner, C.G., and Schwartz, R.H. (1999) Inhibition of cell cycle progression by rapamycin induces T cell clonal anergy even in the presence of costimulation. J Immunol 162: 2775-2784.
-
(1999)
J Immunol
, vol.162
, pp. 2775-2784
-
-
Powell, J.D.1
Lerner, C.G.2
Schwartz, R.H.3
-
28
-
-
84856853119
-
Evidence for conserved function of gamma-glutamyltranspeptidase in Helicobacter genus
-
Rossi, M., Bolz, C., Revez, J., Javed, S., El-Najjar, N., Anderl, F., etal. (2012) Evidence for conserved function of gamma-glutamyltranspeptidase in Helicobacter genus. PLoS ONE 7: e30543.
-
(2012)
PLoS ONE
, vol.7
, pp. e30543
-
-
Rossi, M.1
Bolz, C.2
Revez, J.3
Javed, S.4
El-Najjar, N.5
Anderl, F.6
-
29
-
-
84878013732
-
Life in the human stomach: persistence strategies of the bacterial pathogen Helicobacter pylori
-
Salama, N.R., Hartung, M.L., and Muller, A. (2013) Life in the human stomach: persistence strategies of the bacterial pathogen Helicobacter pylori. Nat Rev 11: 385-399.
-
(2013)
Nat Rev
, vol.11
, pp. 385-399
-
-
Salama, N.R.1
Hartung, M.L.2
Muller, A.3
-
30
-
-
34247594931
-
Inhibition of T-cell proliferation by Helicobacter pylori gamma-glutamyl transpeptidase
-
Schmees, C., Prinz, C., Treptau, T., Rad, R., Hengst, L., Voland, P., etal. (2007) Inhibition of T-cell proliferation by Helicobacter pylori gamma-glutamyl transpeptidase. Gastroenterology 132: 1820-1833.
-
(2007)
Gastroenterology
, vol.132
, pp. 1820-1833
-
-
Schmees, C.1
Prinz, C.2
Treptau, T.3
Rad, R.4
Hengst, L.5
Voland, P.6
-
31
-
-
34247376049
-
Metabolism of glutamine and glutathione via gamma-glutamyltranspeptidase and glutamate transport in Helicobacter pylori: possible significance in the pathophysiology of the organism
-
Shibayama, K., Wachino, J., Arakawa, Y., Saidijam, M., Rutherford, N.G., and Henderson, P.J. (2007) Metabolism of glutamine and glutathione via gamma-glutamyltranspeptidase and glutamate transport in Helicobacter pylori: possible significance in the pathophysiology of the organism. Mol Microbiol 64: 396-406.
-
(2007)
Mol Microbiol
, vol.64
, pp. 396-406
-
-
Shibayama, K.1
Wachino, J.2
Arakawa, Y.3
Saidijam, M.4
Rutherford, N.G.5
Henderson, P.J.6
-
32
-
-
0035953179
-
Helicobacter pylori decreases gastric mucosal glutathione
-
Shirin, H., Pinto, J.T., Liu, L.U., Merzianu, M., Sordillo, E.M., and Moss, S.F. (2001) Helicobacter pylori decreases gastric mucosal glutathione. Cancer Lett 164: 127-133.
-
(2001)
Cancer Lett
, vol.164
, pp. 127-133
-
-
Shirin, H.1
Pinto, J.T.2
Liu, L.U.3
Merzianu, M.4
Sordillo, E.M.5
Moss, S.F.6
-
33
-
-
79953702794
-
Role of the cag-pathogenicity island encoded type IV secretion system in Helicobacter pylori pathogenesis
-
Tegtmeyer, N., Wessler, S., and Backert, S. (2011) Role of the cag-pathogenicity island encoded type IV secretion system in Helicobacter pylori pathogenesis. FEBS J 278: 1190-1202.
-
(2011)
FEBS J
, vol.278
, pp. 1190-1202
-
-
Tegtmeyer, N.1
Wessler, S.2
Backert, S.3
-
34
-
-
84865301337
-
mTOR, metabolism, and the regulation of T-cell differentiation and function
-
Waickman, A.T., and Powell, J.D. (2012) mTOR, metabolism, and the regulation of T-cell differentiation and function. Immunol Rev 249: 43-58.
-
(2012)
Immunol Rev
, vol.249
, pp. 43-58
-
-
Waickman, A.T.1
Powell, J.D.2
-
35
-
-
84255199079
-
The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation
-
Wang, R., Dillon, C.P., Shi, L.Z., Milasta, S., Carter, R., Finkelstein, D., etal. (2011) The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation. Immunity 35: 871-882.
-
(2011)
Immunity
, vol.35
, pp. 871-882
-
-
Wang, R.1
Dillon, C.P.2
Shi, L.Z.3
Milasta, S.4
Carter, R.5
Finkelstein, D.6
-
36
-
-
0034932504
-
Sites of pH regulation of the urea channel of Helicobacter pylori
-
Weeks, D.L., and Sachs, G. (2001) Sites of pH regulation of the urea channel of Helicobacter pylori. Mol Microbiol 40: 1249-1259.
-
(2001)
Mol Microbiol
, vol.40
, pp. 1249-1259
-
-
Weeks, D.L.1
Sachs, G.2
-
37
-
-
67650355074
-
Intestinal epithelial cell proteome from wild-type and TNFDeltaARE/WT mice: effect of iron on the development of chronic ileitis
-
Werner, T., Hoermannsperger, G., Schuemann, K., Hoelzlwimmer, G., Tsuji, S., and Haller, D. (2009) Intestinal epithelial cell proteome from wild-type and TNFDeltaARE/WT mice: effect of iron on the development of chronic ileitis. J Proteome Res 8: 3252-3264.
-
(2009)
J Proteome Res
, vol.8
, pp. 3252-3264
-
-
Werner, T.1
Hoermannsperger, G.2
Schuemann, K.3
Hoelzlwimmer, G.4
Tsuji, S.5
Haller, D.6
-
38
-
-
84887507709
-
Interferon regulatory factor 4 sustains CD8(+) T cell expansion and effector differentiation
-
Yao, S., Buzo, B.F., Pham, D., Jiang, L., Taparowsky, E.J., Kaplan, M.H., and Sun, J. (2013) Interferon regulatory factor 4 sustains CD8(+) T cell expansion and effector differentiation. Immunity 39: 833-845.
-
(2013)
Immunity
, vol.39
, pp. 833-845
-
-
Yao, S.1
Buzo, B.F.2
Pham, D.3
Jiang, L.4
Taparowsky, E.J.5
Kaplan, M.H.6
Sun, J.7
-
39
-
-
0030745596
-
Glutamine requirement of proliferating T lymphocytes
-
Yaqoob, P., and Calder, P.C. (1997) Glutamine requirement of proliferating T lymphocytes. Nutrition 13: 646-651.
-
(1997)
Nutrition
, vol.13
, pp. 646-651
-
-
Yaqoob, P.1
Calder, P.C.2
-
40
-
-
33846909503
-
A role for mammalian target of rapamycin in regulating T cell activation versus anergy
-
Zheng, Y., Collins, S.L., Lutz, M.A., Allen, A.N., Kole, T.P., Zarek, P.E., and Powell, J.D. (2007) A role for mammalian target of rapamycin in regulating T cell activation versus anergy. J Immunol 178: 2163-2170.
-
(2007)
J Immunol
, vol.178
, pp. 2163-2170
-
-
Zheng, Y.1
Collins, S.L.2
Lutz, M.A.3
Allen, A.N.4
Kole, T.P.5
Zarek, P.E.6
Powell, J.D.7
|