Synthesis and biological evaluation of novel sarsasapogenin derivatives as potential anti-tumor agents

Steroids

Volumn 93, Issue , 2015, Pages 25-31

  Yin, Yuan ^a   Zhao, Xun Chen ^a   Wang, Shao Jie ^a   Gao, Pin Yi ^b   Li, Ling Zhi ^a   Ikejima, Takshi ^a   Song, Shao Jiang ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b SHENYANG UNIVERSITY OF CHEMICAL TECHNOLOGY   (China)

Author keywords

26 Aminofurostan derivatives; 3 Aminospirostan derivatives; Anti tumor activity; Sarsasapogenin; Spirostan

Indexed keywords

(22,25) 26 BROMO 3BETA METHOXY 5BETA FUROSTAN; (22,25) 26 DIETHYLAMINO 3BETA METHOXY 5BETA FUROSTAN; (22,25) 26 DIMETHYLAMINO 3BETA METHOXY 5BETA FUROSTAN; (22,25) 3BETA METHOXY 26 (4 METHYLPIPERAZINYLAMINO) 5BETA FUROSTAN; (22,25) 3BETA METHOXY 26 MORPHOLINYLAMINO 5BETA FUROSTAN; (22,25) 3BETA METHOXY 26 PIPERAZINYLAMINO 5BETA FUROSTAN; (22,25) 3BETA METHOXY 26 PIPERIDINYLAMINO 5BETA FUROSTAN; (22,25) 3BETA METHOXY 26 PYRROLIDINYLAMINO 5BETA FUROSTAN; (22,25) 3BETA METHOXY 5BETA FUROSTAN 26 OL; (25) 3ALPHA BROMO 5BETA SPIROSTAN; (25) 3BETA (4 METHYLPIPERAZINYLAMINO) 5BETA SPIROSTAN; (25) 3BETA DIETHYLAMINO 5BETA SPIROSTAN; (25) 3BETA DIMETHYLAMINO 5BETA SPIROSTAN; (25) 3BETA METHOXY 5BETA SPIROSTAN; (25) 3BETA MORPHOLINYLAMINO 5BETA SPIROSTAN; (25) 3BETA PIPERAZINYLAMINO 5BETA SPIROSTAN; (25) 3BETA PIPERIDINYLAMINO 5BETA SPIROSTAN; (25) 3BETA PYRROLIDINYLAMINO 5BETA SPIROSTAN; ANTINEOPLASTIC AGENT; COMPLEMENT; COMPLEMENT COMPONENT C26; COMPLEMENT COMPONENT C3; FLUOROURACIL; SAPOGENIN; SARSASAPOGENIN; SARSASAPOGENIN DERIVATIVE; TIMOSAPONIN A III; UNCLASSIFIED DRUG; SPIROSTAN DERIVATIVE;

ARTICLE; CANCER CELL LINE; CONTROLLED STUDY; CYTOTOXICITY; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC50; IN VITRO STUDY; SYNTHESIS; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; INHIBITORY CONCENTRATION 50; SAPOGENINS; SPIROSTANS;

EID: 84918802171     PISSN: 0039128X     EISSN: 18785867     Source Type: Journal    
DOI: 10.1016/j.steroids.2014.09.007     Document Type: Article

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