Pressure effects reveal that changes in the redox states of the heme iron complexes in the sensor domains of two heme-based oxygen sensor proteins, EcDOS and YddV, have profound effects on their flexibility

FEBS Journal

Volumn 281, Issue 23, 2014, Pages 5208-5219

  Anzenbacher, Pavel ^a   Marchal, Stéphane ^b,c   Palacký, Jan ^a   Anzenbacherová, Eva ^a   Domaschke, Thomas ^b   Lange, Reinhard ^b,d   Shimizu, Toru ^e   Kitanishi, Kenichi ^e   Stranava, Martin ^e   Stiborová, Marie ^e   Martinkova, Marketa ^e  

^a PALACKÝ UNIVERSITY   (Czech Republic)

^b University of Montpellier   (France)

^c HÔPITAL ARNAUD DE VILLENEUVE   (France)

^d UMR IATE   (France)

^e CHARLES UNIVERSITY   (Czech Republic)

Author keywords

Heme based oxygen sensor; Intramolecular catalytic regulation; Pressure effects; Protein compressibility; Protein flexibility

Indexed keywords

CARBON MONOXIDE; CYCLIC GMP; ECDOS PROTEIN; HEME; IRON; IRON COMPLEX; LIGAND; OXYGEN; PHOSPHODIESTERASE; UNCLASSIFIED DRUG; YDDV PROTEIN; DOSP PROTEIN, E COLI; ESCHERICHIA COLI PROTEIN; LYASE; YDDV PROTEIN, E COLI;

AMINO TERMINAL SEQUENCE; ARTICLE; CATALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; ESCHERICHIA COLI; GENE MUTATION; HYDROSTATIC PRESSURE; NONHUMAN; OXIDATION REDUCTION STATE; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PURIFICATION; SENSOR; X RAY CRYSTALLOGRAPHY; CHEMISTRY; OXIDATION REDUCTION REACTION; PROTEIN TERTIARY STRUCTURE; ULTRAVIOLET SPECTROPHOTOMETRY;

ESCHERICHIA COLI;

CATALYSIS; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; HYDROSTATIC PRESSURE; OXIDATION-REDUCTION; PHOSPHORIC DIESTER HYDROLASES; PHOSPHORUS-OXYGEN LYASES; PROTEIN STRUCTURE, TERTIARY; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 84918797914     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.13060     Document Type: Article

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