메뉴 건너뛰기




Volumn 15, Issue 5, 2014, Pages 425-444

Dermatological Toxicity Associated with Targeted Therapies in Cancer: Optimal Management

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS INHIBITOR; ANTINEOPLASTIC AGENT; B RAF KINASE INHIBITOR; BCR ABL PROTEIN INHIBITOR; CYTOTOXIC T LYMPHOCYTE ASSOCIATED PROTEIN 4 INHIBITOR; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PLATELET DERIVED GROWTH FACTOR RECEPTOR INHIBITOR; PROTEIN INHIBITOR; SMOOTHENED INHIBITOR; STEM CELL FACTOR INHIBITOR; UNCLASSIFIED DRUG;

EID: 84918778473     PISSN: 11750561     EISSN: 11791888     Source Type: Journal    
DOI: 10.1007/s40257-014-0088-2     Document Type: Article
Times cited : (33)

References (85)
  • 1
    • 84861199721 scopus 로고    scopus 로고
    • Recommendations on management of EGFR inhibitor-induced skin toxicity: a systematic review
    • PID: 22100458, COI: 1:STN:280:DC%2BC38znsleksA%3D%3D
    • Baas JM, Krens LL, Guchelaar HJ, Ouwerkerk J, de Jong FA, Lavrijsen AP, et al. Recommendations on management of EGFR inhibitor-induced skin toxicity: a systematic review. Cancer Treat Rev. 2012;38(5):505–14.
    • (2012) Cancer Treat Rev , vol.38 , Issue.5 , pp. 505-514
    • Baas, J.M.1    Krens, L.L.2    Guchelaar, H.J.3    Ouwerkerk, J.4    de Jong, F.A.5    Lavrijsen, A.P.6
  • 2
    • 79952208752 scopus 로고    scopus 로고
    • Management of cutaneous side effects of EGFR inhibitors: recommendations from a German expert panel for the primary treating physician
    • PID: 21059173
    • Gutzmer R, Becker JC, Enk A, Garbe C, Hauschild A, Leverkus M, et al. Management of cutaneous side effects of EGFR inhibitors: recommendations from a German expert panel for the primary treating physician. J Dtsch Dermatol Ges. 2011;9(3):195–203.
    • (2011) J Dtsch Dermatol Ges , vol.9 , Issue.3 , pp. 195-203
    • Gutzmer, R.1    Becker, J.C.2    Enk, A.3    Garbe, C.4    Hauschild, A.5    Leverkus, M.6
  • 3
    • 84859387313 scopus 로고    scopus 로고
    • Advances in the management of cutaneous toxicities of targeted therapies
    • PID: 22484194, COI: 1:CAS:528:DC%2BC38Xltlagtbc%3D
    • Robert C, Sibaud V, Mateus C, Cherpelis BS. Advances in the management of cutaneous toxicities of targeted therapies. Semin Oncol. 2012;39(2):227–40.
    • (2012) Semin Oncol , vol.39 , Issue.2 , pp. 227-240
    • Robert, C.1    Sibaud, V.2    Mateus, C.3    Cherpelis, B.S.4
  • 4
    • 84984568870 scopus 로고    scopus 로고
    • Clinical practice guidelines for the prevention and treatment of EGFR inhibitor-associated dermatologic toxicities
    • PID: 21630130
    • Lacouture ME, Anadkat MJ, Bensadoun RJ, Bryce J, Chan A, Epstein JB, et al. Clinical practice guidelines for the prevention and treatment of EGFR inhibitor-associated dermatologic toxicities. Support Care Cancer. 2011;19(8):1079–95.
    • (2011) Support Care Cancer , vol.19 , Issue.8 , pp. 1079-1095
    • Lacouture, M.E.1    Anadkat, M.J.2    Bensadoun, R.J.3    Bryce, J.4    Chan, A.5    Epstein, J.B.6
  • 5
    • 79952013114 scopus 로고    scopus 로고
    • Interdisciplinary management of EGFR-inhibitor-induced skin reactions: a German expert opinion
    • PID: 20709812
    • Potthoff K, Hofheinz R, Hassel JC, Volkenandt M, Lordick F, Hartmann JT, et al. Interdisciplinary management of EGFR-inhibitor-induced skin reactions: a German expert opinion. Ann Oncol. 2010;22(3):524–35.
    • (2010) Ann Oncol , vol.22 , Issue.3 , pp. 524-535
    • Potthoff, K.1    Hofheinz, R.2    Hassel, J.C.3    Volkenandt, M.4    Lordick, F.5    Hartmann, J.T.6
  • 6
    • 84860287213 scopus 로고    scopus 로고
    • Folliculitis induced by EGFR inhibitors, preventive and curative efficacy of tetracyclines in the management and incidence rates according to the type of EGFR inhibitor administered: a systematic literature review
    • PID: 22426526, COI: 1:CAS:528:DC%2BC38XptFWrur8%3D
    • Bachet JB, Peuvrel L, Bachmeyer C, Reguiai Z, Gourraud PA, Bouche O, et al. Folliculitis induced by EGFR inhibitors, preventive and curative efficacy of tetracyclines in the management and incidence rates according to the type of EGFR inhibitor administered: a systematic literature review. Oncologist. 2012;17(4):555–68.
    • (2012) Oncologist , vol.17 , Issue.4 , pp. 555-568
    • Bachet, J.B.1    Peuvrel, L.2    Bachmeyer, C.3    Reguiai, Z.4    Gourraud, P.A.5    Bouche, O.6
  • 7
    • 74049120784 scopus 로고    scopus 로고
    • Dermatologic infections in cancer patients treated with epidermal growth factor receptor inhibitor therapy
    • PID: 20007525, COI: 1:CAS:528:DC%2BC3cXkt1Cluw%3D%3D
    • Eilers RE Jr, Gandhi M, Patel JD, Mulcahy MF, Agulnik M, Hensing T, et al. Dermatologic infections in cancer patients treated with epidermal growth factor receptor inhibitor therapy. J Natl Cancer Inst. 2010;102(1):47–53.
    • (2010) J Natl Cancer Inst , vol.102 , Issue.1 , pp. 47-53
    • Eilers, R.E.1    Gandhi, M.2    Patel, J.D.3    Mulcahy, M.F.4    Agulnik, M.5    Hensing, T.6
  • 8
    • 50249101750 scopus 로고    scopus 로고
    • Tetracycline to prevent epidermal growth factor receptor inhibitor-induced skin rashes: results of a placebo-controlled trial from the North Central Cancer Treatment Group (N03CB)
    • PID: 18543329, COI: 1:CAS:528:DC%2BD1cXhtVGhsbbP
    • Jatoi A, Rowland K, Sloan JA, Gross HM, Fishkin PA, Kahanic SP, et al. Tetracycline to prevent epidermal growth factor receptor inhibitor-induced skin rashes: results of a placebo-controlled trial from the North Central Cancer Treatment Group (N03CB). Cancer. 2008;113(4):847–53.
    • (2008) Cancer , vol.113 , Issue.4 , pp. 847-853
    • Jatoi, A.1    Rowland, K.2    Sloan, J.A.3    Gross, H.M.4    Fishkin, P.A.5    Kahanic, S.P.6
  • 9
    • 77957818555 scopus 로고    scopus 로고
    • Does sunscreen prevent epidermal growth factor receptor (EGFR) inhibitor-induced rash? Results of a placebo-controlled trial from the North Central Cancer Treatment Group (N05C4)
    • PID: 20798191
    • Jatoi A, Thrower A, Sloan JA, Flynn PJ, Wentworth-Hartung NL, Dakhil SR, et al. Does sunscreen prevent epidermal growth factor receptor (EGFR) inhibitor-induced rash? Results of a placebo-controlled trial from the North Central Cancer Treatment Group (N05C4). Oncologist. 2010;15(9):1016–22.
    • (2010) Oncologist , vol.15 , Issue.9 , pp. 1016-1022
    • Jatoi, A.1    Thrower, A.2    Sloan, J.A.3    Flynn, P.J.4    Wentworth-Hartung, N.L.5    Dakhil, S.R.6
  • 10
    • 77950495095 scopus 로고    scopus 로고
    • Skin toxicity evaluation protocol with panitumumab (STEPP), a phase II, open-label, randomized trial evaluating the impact of a pre-emptive skin treatment regimen on skin toxicities and quality of life in patients with metastatic colorectal cancer
    • PID: 20142600, COI: 1:CAS:528:DC%2BC3cXksFSqtbc%3D
    • Lacouture ME, Mitchell EP, Piperdi B, Pillai MV, Shearer H, Iannotti N, et al. Skin toxicity evaluation protocol with panitumumab (STEPP), a phase II, open-label, randomized trial evaluating the impact of a pre-emptive skin treatment regimen on skin toxicities and quality of life in patients with metastatic colorectal cancer. J Clin Oncol. 2010;28(8):1351–7.
    • (2010) J Clin Oncol , vol.28 , Issue.8 , pp. 1351-1357
    • Lacouture, M.E.1    Mitchell, E.P.2    Piperdi, B.3    Pillai, M.V.4    Shearer, H.5    Iannotti, N.6
  • 11
    • 36849093857 scopus 로고    scopus 로고
    • Randomized double-blind trial of prophylactic oral minocycline and topical tazarotene for cetuximab-associated acne-like eruption
    • PID: 18048820, COI: 1:CAS:528:DC%2BD1cXnvVCjtA%3D%3D
    • Scope A, Agero AL, Dusza SW, Myskowski PL, Lieb JA, Saltz L, et al. Randomized double-blind trial of prophylactic oral minocycline and topical tazarotene for cetuximab-associated acne-like eruption. J Clin Oncol. 2007;25(34):5390–6.
    • (2007) J Clin Oncol , vol.25 , Issue.34 , pp. 5390-5396
    • Scope, A.1    Agero, A.L.2    Dusza, S.W.3    Myskowski, P.L.4    Lieb, J.A.5    Saltz, L.6
  • 12
    • 66749140972 scopus 로고    scopus 로고
    • A prospective randomized trial of topical pimecrolimus for cetuximab-associated acnelike eruption
    • PID: 19646778, COI: 1:CAS:528:DC%2BD1MXhtlWks7zP
    • Scope A, Lieb JA, Dusza SW, Phelan DL, Myskowski PL, Saltz L, et al. A prospective randomized trial of topical pimecrolimus for cetuximab-associated acnelike eruption. J Am Acad Dermatol. 2009;61(4):614–20.
    • (2009) J Am Acad Dermatol , vol.61 , Issue.4 , pp. 614-620
    • Scope, A.1    Lieb, J.A.2    Dusza, S.W.3    Phelan, D.L.4    Myskowski, P.L.5    Saltz, L.6
  • 13
    • 84863982274 scopus 로고    scopus 로고
    • Management of cutaneous adverse events induced by anti-EGFR (epidermal growth factor receptor): a French interdisciplinary therapeutic algorithm
    • PID: 22539049, COI: 1:STN:280:DC%2BC38rosFCqtg%3D%3D
    • Reguiai Z, Bachet JB, Bachmeyer C, Peuvrel L, Beylot-Barry M, Bezier M, et al. Management of cutaneous adverse events induced by anti-EGFR (epidermal growth factor receptor): a French interdisciplinary therapeutic algorithm. Support Care Cancer. 2012;20(7):1395–404.
    • (2012) Support Care Cancer , vol.20 , Issue.7 , pp. 1395-1404
    • Reguiai, Z.1    Bachet, J.B.2    Bachmeyer, C.3    Peuvrel, L.4    Beylot-Barry, M.5    Bezier, M.6
  • 14
    • 69149096621 scopus 로고    scopus 로고
    • Cutaneous side-effects in patients on long-term treatment with epidermal growth factor receptor inhibitors
    • PID: 19466958, COI: 1:STN:280:DC%2BD1MrnsleltQ%3D%3D
    • Osio A, Mateus C, Soria JC, Massard C, Malka D, Boige V, et al. Cutaneous side-effects in patients on long-term treatment with epidermal growth factor receptor inhibitors. Br J Dermatol. 2009;161(3):515–21.
    • (2009) Br J Dermatol , vol.161 , Issue.3 , pp. 515-521
    • Osio, A.1    Mateus, C.2    Soria, J.C.3    Massard, C.4    Malka, D.5    Boige, V.6
  • 15
    • 84889865881 scopus 로고    scopus 로고
    • Daily baseline skin care in the prevention, treatment, and supportive care of skin toxicity in oncology patients: recommendations from a multinational expert panel
    • PID: 24353440
    • Bensadoun RJ, Humbert P, Krutman J, Luger T, Triller R, Rougier A, et al. Daily baseline skin care in the prevention, treatment, and supportive care of skin toxicity in oncology patients: recommendations from a multinational expert panel. Cancer Manag Res. 2013;5:401–8.
    • (2013) Cancer Manag Res , vol.5 , pp. 401-408
    • Bensadoun, R.J.1    Humbert, P.2    Krutman, J.3    Luger, T.4    Triller, R.5    Rougier, A.6
  • 16
    • 63449110924 scopus 로고    scopus 로고
    • Increased risk of high-grade dermatologic toxicities with radiation plus epidermal growth factor receptor inhibitor therapy
    • PID: 19170238, COI: 1:CAS:528:DC%2BD1MXktlKnsLw%3D
    • Tejwani A, Wu S, Jia Y, Agulnik M, Millender L, Lacouture ME. Increased risk of high-grade dermatologic toxicities with radiation plus epidermal growth factor receptor inhibitor therapy. Cancer. 2009;115(6):1286–99.
    • (2009) Cancer , vol.115 , Issue.6 , pp. 1286-1299
    • Tejwani, A.1    Wu, S.2    Jia, Y.3    Agulnik, M.4    Millender, L.5    Lacouture, M.E.6
  • 17
    • 61449090567 scopus 로고    scopus 로고
    • Analysis of dermatologic events in patients with cancer treated with lapatinib
    • PID: 18600445, COI: 1:CAS:528:DC%2BD1MXisFSqt7k%3D
    • Lacouture ME, Laabs SM, Koehler M, Sweetman RW, Preston AJ, Di Leo A, et al. Analysis of dermatologic events in patients with cancer treated with lapatinib. Breast Cancer Res Treat. 2009;114(3):485–93.
    • (2009) Breast Cancer Res Treat , vol.114 , Issue.3 , pp. 485-493
    • Lacouture, M.E.1    Laabs, S.M.2    Koehler, M.3    Sweetman, R.W.4    Preston, A.J.5    Di Leo, A.6
  • 18
    • 84864422683 scopus 로고    scopus 로고
    • Escalating therapy of cutaneous side effects of EGFR inhibitors: experience of German reference centers
    • PID: 22672156
    • Homey B, Gerber PA, Wollenberg A, Dirschka T, Hassel JC, Bolke E, et al. Escalating therapy of cutaneous side effects of EGFR inhibitors: experience of German reference centers. J Dtsch Dermatol Ges. 2012;10(8):559–63.
    • (2012) J Dtsch Dermatol Ges , vol.10 , Issue.8 , pp. 559-563
    • Homey, B.1    Gerber, P.A.2    Wollenberg, A.3    Dirschka, T.4    Hassel, J.C.5    Bolke, E.6
  • 19
    • 79251587195 scopus 로고    scopus 로고
    • Integrating bevacizumab, everolimus, and lapatinib into current neoadjuvant chemotherapy regimen for primary breast cancer. Safety results of the GeparQuinto trial
    • von Minckwitz G, Eidtmann H, Loibl S, Blohmer JU, Costa SD, Fasching PA, et al. Integrating bevacizumab, everolimus, and lapatinib into current neoadjuvant chemotherapy regimen for primary breast cancer. Safety results of the GeparQuinto trial. Ann Oncol. 2011;22(2):301–6.
    • (2011) Ann Oncol , vol.22 , Issue.2 , pp. 301-306
    • von Minckwitz, G.1    Eidtmann, H.2    Loibl, S.3    Blohmer, J.U.4    Costa, S.D.5    Fasching, P.A.6
  • 20
    • 73349116875 scopus 로고    scopus 로고
    • Geographic distribution of lapatinib-induced skin rash: sparing of abdominal skin persists in the transverse rectus abdominis myocutaneous flap
    • PID: 19786662
    • Lin NU, Kasparian E, Morganstern DE, Beard C. Geographic distribution of lapatinib-induced skin rash: sparing of abdominal skin persists in the transverse rectus abdominis myocutaneous flap. J Clin Oncol. 2009;27(34):e218–9.
    • (2009) J Clin Oncol , vol.27 , Issue.34 , pp. e218-e219
    • Lin, N.U.1    Kasparian, E.2    Morganstern, D.E.3    Beard, C.4
  • 21
    • 84862785051 scopus 로고    scopus 로고
    • Afatinib versus placebo for patients with advanced, metastatic non-small-cell lung cancer after failure of erlotinib, gefitinib, or both, and one or two lines of chemotherapy (LUX-Lung 1): a phase 2b/3 randomised trial
    • PID: 22452896, COI: 1:CAS:528:DC%2BC38Xmslyhsbg%3D
    • Miller VA, Hirsh V, Cadranel J, Chen YM, Park K, Kim SW, et al. Afatinib versus placebo for patients with advanced, metastatic non-small-cell lung cancer after failure of erlotinib, gefitinib, or both, and one or two lines of chemotherapy (LUX-Lung 1): a phase 2b/3 randomised trial. Lancet Oncol. 2012;13(5):528–38.
    • (2012) Lancet Oncol , vol.13 , Issue.5 , pp. 528-538
    • Miller, V.A.1    Hirsh, V.2    Cadranel, J.3    Chen, Y.M.4    Park, K.5    Kim, S.W.6
  • 22
    • 77957585027 scopus 로고    scopus 로고
    • Phase I trial of the irreversible EGFR and HER2 kinase inhibitor BIBW 2992 in patients with advanced solid tumors
    • PID: 20679611, COI: 1:CAS:528:DC%2BC3cXht1eqsbzF
    • Yap TA, Vidal L, Adam J, Stephens P, Spicer J, Shaw H, et al. Phase I trial of the irreversible EGFR and HER2 kinase inhibitor BIBW 2992 in patients with advanced solid tumors. J Clin Oncol. 2010;28(25):3965–72.
    • (2010) J Clin Oncol , vol.28 , Issue.25 , pp. 3965-3972
    • Yap, T.A.1    Vidal, L.2    Adam, J.3    Stephens, P.4    Spicer, J.5    Shaw, H.6
  • 23
    • 84861447222 scopus 로고    scopus 로고
    • Cutaneous drug eruptions associated with the use of new oncological drugs
    • PID: 22613863, COI: 1:CAS:528:DC%2BC38XhslSns73N
    • Belloni B, Schonewolf N, Rozati S, Goldinger SM, Dummer R. Cutaneous drug eruptions associated with the use of new oncological drugs. Chem Immunol Allergy. 2012;97:191–202.
    • (2012) Chem Immunol Allergy , vol.97 , pp. 191-202
    • Belloni, B.1    Schonewolf, N.2    Rozati, S.3    Goldinger, S.M.4    Dummer, R.5
  • 24
    • 84875453915 scopus 로고    scopus 로고
    • Analysis of dermatologic events in vemurafenib-treated patients with melanoma
    • PID: 23457002, COI: 1:CAS:528:DC%2BC3sXotFSjsbc%3D
    • Lacouture ME, Duvic M, Hauschild A, Prieto VG, Robert C, Schadendorf D, et al. Analysis of dermatologic events in vemurafenib-treated patients with melanoma. Oncologist. 2013;18(3):314–22.
    • (2013) Oncologist , vol.18 , Issue.3 , pp. 314-322
    • Lacouture, M.E.1    Duvic, M.2    Hauschild, A.3    Prieto, V.G.4    Robert, C.5    Schadendorf, D.6
  • 25
    • 84872857932 scopus 로고    scopus 로고
    • Cutaneous side effects of inhibitors of the RAS/RAF/MEK/ERK signalling pathway and their management
    • PID: 22540151
    • Manousaridis I, Mavridou S, Goerdt S, Leverkus M, Utikal J. Cutaneous side effects of inhibitors of the RAS/RAF/MEK/ERK signalling pathway and their management. J Eur Acad Dermatol Venereol. 2012;27(1):11–8.
    • (2012) J Eur Acad Dermatol Venereol , vol.27 , Issue.1 , pp. 11-18
    • Manousaridis, I.1    Mavridou, S.2    Goerdt, S.3    Leverkus, M.4    Utikal, J.5
  • 26
    • 84857012981 scopus 로고    scopus 로고
    • Novel treatments for metastatic cutaneous melanoma and the management of emergent toxicities
    • PID: 22253555, COI: 1:CAS:528:DC%2BC38XhvVylur8%3D
    • Lemech C, Arkenau HT. Novel treatments for metastatic cutaneous melanoma and the management of emergent toxicities. Clin Med Insights Oncol. 2012;6:53–66.
    • (2012) Clin Med Insights Oncol , vol.6 , pp. 53-66
    • Lemech, C.1    Arkenau, H.T.2
  • 27
    • 84859831660 scopus 로고    scopus 로고
    • Dermatologic adverse events of the new targeted anticancer therapies used in oncodermatology
    • PID: 22425393, COI: 1:STN:280:DC%2BC38vnt1ygsw%3D%3D
    • Sibaud V, Delord JP, Chevreau C, Gangloff D, Garrido-Stowhas I. Dermatologic adverse events of the new targeted anticancer therapies used in oncodermatology. Ann Chir Plast Esthet. 2012;57(2):106–13.
    • (2012) Ann Chir Plast Esthet , vol.57 , Issue.2 , pp. 106-113
    • Sibaud, V.1    Delord, J.P.2    Chevreau, C.3    Gangloff, D.4    Garrido-Stowhas, I.5
  • 28
    • 84878451069 scopus 로고    scopus 로고
    • Prospective study of cutaneous side-effects associated with the BRAF inhibitor vemurafenib: a study of 42 patients
    • PID: 23406731, COI: 1:STN:280:DC%2BC3szotVOktQ%3D%3D
    • Boussemart L, Routier E, Mateus C, Opletalova K, Sebille G, Kamsu-Kom N, et al. Prospective study of cutaneous side-effects associated with the BRAF inhibitor vemurafenib: a study of 42 patients. Ann Oncol. 2013;24(6):1691–7.
    • (2013) Ann Oncol , vol.24 , Issue.6 , pp. 1691-1697
    • Boussemart, L.1    Routier, E.2    Mateus, C.3    Opletalova, K.4    Sebille, G.5    Kamsu-Kom, N.6
  • 29
    • 84868193136 scopus 로고    scopus 로고
    • Cutaneous manifestations of dabrafenib (GSK2118436): a selective inhibitor of mutant BRAF in patients with metastatic melanoma
    • PID: 22804352, COI: 1:CAS:528:DC%2BC38Xhs1ShtbnP
    • Anforth RM, Blumetti TC, Kefford RF, Sharma R, Scolyer RA, Kossard S, et al. Cutaneous manifestations of dabrafenib (GSK2118436): a selective inhibitor of mutant BRAF in patients with metastatic melanoma. Br J Dermatol. 2012;167(5):1153–60.
    • (2012) Br J Dermatol , vol.167 , Issue.5 , pp. 1153-1160
    • Anforth, R.M.1    Blumetti, T.C.2    Kefford, R.F.3    Sharma, R.4    Scolyer, R.A.5    Kossard, S.6
  • 32
    • 84856582443 scopus 로고    scopus 로고
    • Ultraviolet A and photosensitivity during vemurafenib therapy
    • PID: 22296092, COI: 1:CAS:528:DC%2BC38XitVShurk%3D
    • Dummer R, Rinderknecht J, Goldinger SM. Ultraviolet A and photosensitivity during vemurafenib therapy. N Engl J Med. 2012;366(5):480–1.
    • (2012) N Engl J Med , vol.366 , Issue.5 , pp. 480-481
    • Dummer, R.1    Rinderknecht, J.2    Goldinger, S.M.3
  • 33
    • 84900838040 scopus 로고    scopus 로고
    • Melanoma patients under vemurafenib: prospective follow-up of melanocytic lesions by digital dermoscopy
    • PID: 24304815, COI: 1:CAS:528:DC%2BC3sXhvVOiu77N
    • Perier-Muzet M, Thomas L, Poulalhon N, Debarbieux S, Bringuier PP, Duru G, et al. Melanoma patients under vemurafenib: prospective follow-up of melanocytic lesions by digital dermoscopy. J Invest Dermatol. 2014;134(5):1351–8.
    • (2014) J Invest Dermatol , vol.134 , Issue.5 , pp. 1351-1358
    • Perier-Muzet, M.1    Thomas, L.2    Poulalhon, N.3    Debarbieux, S.4    Bringuier, P.P.5    Duru, G.6
  • 34
    • 84863463901 scopus 로고    scopus 로고
    • Atypical melanocytic proliferations and new primary melanomas in patients with advanced melanoma undergoing selective BRAF inhibition
    • PID: 22614973, COI: 1:CAS:528:DC%2BC38Xht1aisbnK
    • Zimmer L, Hillen U, Livingstone E, Lacouture ME, Busam K, Carvajal RD, et al. Atypical melanocytic proliferations and new primary melanomas in patients with advanced melanoma undergoing selective BRAF inhibition. J Clin Oncol. 2012;30(19):2375–83.
    • (2012) J Clin Oncol , vol.30 , Issue.19 , pp. 2375-2383
    • Zimmer, L.1    Hillen, U.2    Livingstone, E.3    Lacouture, M.E.4    Busam, K.5    Carvajal, R.D.6
  • 35
    • 84878775551 scopus 로고    scopus 로고
    • Appearance of new vemurafenib-associated melanocytic nevi on normal-appearing skin: case series and a review of changing or new pigmented lesions in patients with metastatic malignant melanoma after initiating treatment with vemurafenib
    • PID: 23710269
    • Cohen PR, Bedikian AY, Kim KB. Appearance of new vemurafenib-associated melanocytic nevi on normal-appearing skin: case series and a review of changing or new pigmented lesions in patients with metastatic malignant melanoma after initiating treatment with vemurafenib. J Clin Aesthet Dermatol. 2013;6(5):27–37.
    • (2013) J Clin Aesthet Dermatol , vol.6 , Issue.5 , pp. 27-37
    • Cohen, P.R.1    Bedikian, A.Y.2    Kim, K.B.3
  • 37
    • 84858729203 scopus 로고    scopus 로고
    • Panniculitis with arthralgia in patients with melanoma treated with selective BRAF inhibitors and its management
    • PID: 22250191, COI: 1:CAS:528:DC%2BC38Xmt1ShsLk%3D
    • Zimmer L, Livingstone E, Hillen U, Domkes S, Becker A, Schadendorf D. Panniculitis with arthralgia in patients with melanoma treated with selective BRAF inhibitors and its management. Arch Dermatol. 2012;148(3):357–61.
    • (2012) Arch Dermatol , vol.148 , Issue.3 , pp. 357-361
    • Zimmer, L.1    Livingstone, E.2    Hillen, U.3    Domkes, S.4    Becker, A.5    Schadendorf, D.6
  • 38
    • 76049113589 scopus 로고    scopus 로고
    • Mitogen-activated protein/extracellular signal-regulated kinase kinase inhibition results in biphasic alteration of epidermal homeostasis with keratinocytic apoptosis and pigmentation disorders
    • PID: 20103661, COI: 1:CAS:528:DC%2BC3cXhs1aru7s%3D
    • Schad K, BaumannConzett K, Zipser MC, Enderlin V, Kamarashev J, French LE, et al. Mitogen-activated protein/extracellular signal-regulated kinase kinase inhibition results in biphasic alteration of epidermal homeostasis with keratinocytic apoptosis and pigmentation disorders. Clin Cancer Res. 2010;16(3):1058–64.
    • (2010) Clin Cancer Res , vol.16 , Issue.3 , pp. 1058-1064
    • Schad, K.1    BaumannConzett, K.2    Zipser, M.C.3    Enderlin, V.4    Kamarashev, J.5    French, L.E.6
  • 39
    • 84863673204 scopus 로고    scopus 로고
    • Improved survival with MEK inhibition in BRAF-mutated melanoma
    • PID: 22663011, COI: 1:CAS:528:DC%2BC38XhtFKjs7zN
    • Flaherty KT, Robert C, Hersey P, Nathan P, Garbe C, Milhem M, et al. Improved survival with MEK inhibition in BRAF-mutated melanoma. N Engl J Med. 2012;367(2):107–14.
    • (2012) N Engl J Med , vol.367 , Issue.2 , pp. 107-114
    • Flaherty, K.T.1    Robert, C.2    Hersey, P.3    Nathan, P.4    Garbe, C.5    Milhem, M.6
  • 40
    • 80052020659 scopus 로고    scopus 로고
    • Paronychia and pyogenic granuloma induced by new anticancer mTOR inhibitors
    • PID: 21667012, COI: 1:CAS:528:DC%2BC3MXhsFWisbjN
    • Sibaud V, Dalenc F, Mourey L, Chevreau C. Paronychia and pyogenic granuloma induced by new anticancer mTOR inhibitors. Acta Derm Venereol. 2011;91(5):584–5.
    • (2011) Acta Derm Venereol , vol.91 , Issue.5 , pp. 584-585
    • Sibaud, V.1    Dalenc, F.2    Mourey, L.3    Chevreau, C.4
  • 41
    • 48749128305 scopus 로고    scopus 로고
    • Temsirolimus safety profile and management of toxic effects in patients with advanced renal cell carcinoma and poor prognostic features
    • PID: 18385198, COI: 1:STN:280:DC%2BD1cvotVGqsw%3D%3D
    • Bellmunt J, Szczylik C, Feingold J, Strahs A, Berkenblit A. Temsirolimus safety profile and management of toxic effects in patients with advanced renal cell carcinoma and poor prognostic features. Ann Oncol. 2008;19(8):1387–92.
    • (2008) Ann Oncol , vol.19 , Issue.8 , pp. 1387-1392
    • Bellmunt, J.1    Szczylik, C.2    Feingold, J.3    Strahs, A.4    Berkenblit, A.5
  • 42
    • 79952282127 scopus 로고    scopus 로고
    • Toxicities of targeted therapy and their management in kidney cancer
    • PID: 21277078
    • Di Lorenzo G, Porta C, Bellmunt J, Sternberg C, Kirkali Z, Staehler M, et al. Toxicities of targeted therapy and their management in kidney cancer. Eur Urol. 2011;59(4):526–40.
    • (2011) Eur Urol , vol.59 , Issue.4 , pp. 526-540
    • Di Lorenzo, G.1    Porta, C.2    Bellmunt, J.3    Sternberg, C.4    Kirkali, Z.5    Staehler, M.6
  • 43
    • 73649109111 scopus 로고    scopus 로고
    • Randomized phase II study comparing two schedules of everolimus in patients with recurrent/metastatic breast cancer: NCIC Clinical Trials Group IND.163
    • PID: 19687332, COI: 1:CAS:528:DC%2BD1MXhtlCns77K
    • Ellard SL, Clemons M, Gelmon KA, Norris B, Kennecke H, Chia S, et al. Randomized phase II study comparing two schedules of everolimus in patients with recurrent/metastatic breast cancer: NCIC Clinical Trials Group IND.163. J Clin Oncol. 2009;27(27):4536–41.
    • (2009) J Clin Oncol , vol.27 , Issue.27 , pp. 4536-4541
    • Ellard, S.L.1    Clemons, M.2    Gelmon, K.A.3    Norris, B.4    Kennecke, H.5    Chia, S.6
  • 45
    • 84867337737 scopus 로고    scopus 로고
    • Clinical and histopathologic characteristics of rash in cancer patients treated with mammalian target of rapamycin inhibitors
    • PID: 22437824, COI: 1:CAS:528:DC%2BC38XhsVKltrjI
    • Balagula Y, Rosen A, Tan BH, Busam KJ, Pulitzer MP, Motzer RJ, et al. Clinical and histopathologic characteristics of rash in cancer patients treated with mammalian target of rapamycin inhibitors. Cancer. 2012;118(20):5078–83.
    • (2012) Cancer , vol.118 , Issue.20 , pp. 5078-5083
    • Balagula, Y.1    Rosen, A.2    Tan, B.H.3    Busam, K.J.4    Pulitzer, M.P.5    Motzer, R.J.6
  • 46
    • 79957566962 scopus 로고    scopus 로고
    • Management of adverse events associated with the use of everolimus in patients with advanced renal cell carcinoma
    • PID: 21481584, COI: 1:CAS:528:DC%2BC3MXmvVejs70%3D
    • Porta C, Osanto S, Ravaud A, Climent MA, Vaishampayan U, White DA, et al. Management of adverse events associated with the use of everolimus in patients with advanced renal cell carcinoma. Eur J Cancer. 2011;47(9):1287–98.
    • (2011) Eur J Cancer , vol.47 , Issue.9 , pp. 1287-1298
    • Porta, C.1    Osanto, S.2    Ravaud, A.3    Climent, M.A.4    Vaishampayan, U.5    White, D.A.6
  • 47
    • 1542398693 scopus 로고    scopus 로고
    • Randomized phase II study of multiple dose levels of CCI-779, a novel mammalian target of rapamycin kinase inhibitor, in patients with advanced refractory renal cell carcinoma
    • PID: 14990647, COI: 1:CAS:528:DC%2BD2cXpsVKisr0%3D
    • Atkins MB, Hidalgo M, Stadler WM, Logan TF, Dutcher JP, Hudes GR, et al. Randomized phase II study of multiple dose levels of CCI-779, a novel mammalian target of rapamycin kinase inhibitor, in patients with advanced refractory renal cell carcinoma. J Clin Oncol. 2004;22(5):909–18.
    • (2004) J Clin Oncol , vol.22 , Issue.5 , pp. 909-918
    • Atkins, M.B.1    Hidalgo, M.2    Stadler, W.M.3    Logan, T.F.4    Dutcher, J.P.5    Hudes, G.R.6
  • 48
    • 11344271046 scopus 로고    scopus 로고
    • Population pharmacokinetics of CCI-779: correlations to safety and pharmacogenomic responses in patients with advanced renal cancer
    • PID: 15637533, COI: 1:CAS:528:DC%2BD2MXks1Wq
    • Boni JP, Leister C, Bender G, Fitzpatrick V, Twine N, Stover J, et al. Population pharmacokinetics of CCI-779: correlations to safety and pharmacogenomic responses in patients with advanced renal cancer. Clin Pharmacol Ther. 2005;77(1):76–89.
    • (2005) Clin Pharmacol Ther , vol.77 , Issue.1 , pp. 76-89
    • Boni, J.P.1    Leister, C.2    Bender, G.3    Fitzpatrick, V.4    Twine, N.5    Stover, J.6
  • 49
    • 43249086546 scopus 로고    scopus 로고
    • Phase I pharmacokinetic and pharmacodynamic study of the oral mammalian target of rapamycin inhibitor everolimus in patients with advanced solid tumors
    • PID: 18332470
    • O’Donnell A, Faivre S, Burris HA 3rd, Rea D, Papadimitrakopoulou V, Shand N, et al. Phase I pharmacokinetic and pharmacodynamic study of the oral mammalian target of rapamycin inhibitor everolimus in patients with advanced solid tumors. J Clin Oncol. 2008;26(10):1588–95.
    • (2008) J Clin Oncol , vol.26 , Issue.10 , pp. 1588-1595
    • O’Donnell, A.1    Faivre, S.2    Burris, H.A.3    Rea, D.4    Papadimitrakopoulou, V.5    Shand, N.6
  • 50
    • 43249131245 scopus 로고    scopus 로고
    • Dose- and schedule-dependent inhibition of the mammalian target of rapamycin pathway with everolimus: a phase I tumor pharmacodynamic study in patients with advanced solid tumors
    • PID: 18332469, COI: 1:CAS:528:DC%2BD1cXltlWiu7c%3D
    • Tabernero J, Rojo F, Calvo E, Burris H, Judson I, Hazell K, et al. Dose- and schedule-dependent inhibition of the mammalian target of rapamycin pathway with everolimus: a phase I tumor pharmacodynamic study in patients with advanced solid tumors. J Clin Oncol. 2008;26(10):1603–10.
    • (2008) J Clin Oncol , vol.26 , Issue.10 , pp. 1603-1610
    • Tabernero, J.1    Rojo, F.2    Calvo, E.3    Burris, H.4    Judson, I.5    Hazell, K.6
  • 51
    • 84863784970 scopus 로고    scopus 로고
    • Onychopathy induced by temsirolimus, a mammalian target of rapamycin inhibitor
    • PID: 22614575, COI: 1:STN:280:DC%2BC38nltVKmsA%3D%3D
    • Peuvrel L, Quereux G, Brocard A, Saint-Jean M, Dreno B. Onychopathy induced by temsirolimus, a mammalian target of rapamycin inhibitor. Dermatology. 2012;224(3):204–8.
    • (2012) Dermatology , vol.224 , Issue.3 , pp. 204-208
    • Peuvrel, L.1    Quereux, G.2    Brocard, A.3    Saint-Jean, M.4    Dreno, B.5
  • 52
    • 2942735384 scopus 로고    scopus 로고
    • Safety and pharmacokinetics of escalated doses of weekly intravenous infusion of CCI-779, a novel mTOR inhibitor, in patients with cancer
    • PID: 15136596, COI: 1:CAS:528:DC%2BD2cXpsVWltbc%3D
    • Raymond E, Alexandre J, Faivre S, Vera K, Materman E, Boni J, et al. Safety and pharmacokinetics of escalated doses of weekly intravenous infusion of CCI-779, a novel mTOR inhibitor, in patients with cancer. J Clin Oncol. 2004;22(12):2336–47.
    • (2004) J Clin Oncol , vol.22 , Issue.12 , pp. 2336-2347
    • Raymond, E.1    Alexandre, J.2    Faivre, S.3    Vera, K.4    Materman, E.5    Boni, J.6
  • 54
    • 80052719361 scopus 로고    scopus 로고
    • Adverse cutaneous reactions secondary to tyrosine kinase inhibitors including imatinib mesylate, nilotinib, and dasatinib
    • PID: 21910796
    • Amitay-Laish I, Stemmer SM, Lacouture ME. Adverse cutaneous reactions secondary to tyrosine kinase inhibitors including imatinib mesylate, nilotinib, and dasatinib. Dermatol Ther. 2011;24(4):386–95.
    • (2011) Dermatol Ther , vol.24 , Issue.4 , pp. 386-395
    • Amitay-Laish, I.1    Stemmer, S.M.2    Lacouture, M.E.3
  • 55
    • 70349507949 scopus 로고    scopus 로고
    • Lichenoid drug eruption related to imatinib: report of a new case and review of the literature
    • PID: 19456782, COI: 1:STN:280:DC%2BD1Mnhs1yrsQ%3D%3D
    • Sendagorta E, Herranz P, Feito M, Ramirez P, Feltes R, Floristan U, et al. Lichenoid drug eruption related to imatinib: report of a new case and review of the literature. Clin Exp Dermatol. 2009;34(7):e315–6.
    • (2009) Clin Exp Dermatol , vol.34 , Issue.7 , pp. e315-e316
    • Sendagorta, E.1    Herranz, P.2    Feito, M.3    Ramirez, P.4    Feltes, R.5    Floristan, U.6
  • 56
    • 84903520834 scopus 로고    scopus 로고
    • Ponatinib-induced neutrophilic panniculitis
    • PID: 24602068
    • Zhang M, Hassan KM, Musiek A, Rosman IS. Ponatinib-induced neutrophilic panniculitis. J Cutan Pathol. 2014;41(7):597–601.
    • (2014) J Cutan Pathol , vol.41 , Issue.7 , pp. 597-601
    • Zhang, M.1    Hassan, K.M.2    Musiek, A.3    Rosman, I.S.4
  • 58
    • 71949112710 scopus 로고    scopus 로고
    • Cutaneous adverse effects in patients treated with the multitargeted kinase inhibitors sorafenib and sunitinib
    • PID: 19558553, COI: 1:CAS:528:DC%2BD1MXhsFait7vL
    • Lee WJ, Lee JL, Chang SE, Lee MW, Kang YK, Choi JH, et al. Cutaneous adverse effects in patients treated with the multitargeted kinase inhibitors sorafenib and sunitinib. Br J Dermatol. 2009;161(5):1045–51.
    • (2009) Br J Dermatol , vol.161 , Issue.5 , pp. 1045-1051
    • Lee, W.J.1    Lee, J.L.2    Chang, S.E.3    Lee, M.W.4    Kang, Y.K.5    Choi, J.H.6
  • 59
    • 84867844763 scopus 로고    scopus 로고
    • Antiangiogenic therapy for advanced renal cell carcinoma: management of treatment-related toxicities
    • PID: 22327313, COI: 1:CAS:528:DC%2BC38XhtlWltbnP
    • Cohen RB, Oudard S. Antiangiogenic therapy for advanced renal cell carcinoma: management of treatment-related toxicities. Invest New Drugs. 2012;30(5):2066–79.
    • (2012) Invest New Drugs , vol.30 , Issue.5 , pp. 2066-2079
    • Cohen, R.B.1    Oudard, S.2
  • 60
    • 70449647041 scopus 로고    scopus 로고
    • Hand-foot syndrome (hand-foot skin reaction, palmar-plantar erythrodysesthesia): focus on sorafenib and sunitinib
    • PID: 19923864, COI: 1:CAS:528:DC%2BD1MXhsFOhtrfI
    • Lipworth AD, Robert C, Zhu AX. Hand-foot syndrome (hand-foot skin reaction, palmar-plantar erythrodysesthesia): focus on sorafenib and sunitinib. Oncology. 2009;77(5):257–71.
    • (2009) Oncology , vol.77 , Issue.5 , pp. 257-271
    • Lipworth, A.D.1    Robert, C.2    Zhu, A.X.3
  • 61
    • 84880916933 scopus 로고    scopus 로고
    • Risk of hand-foot skin reaction with the novel multikinase inhibitor regorafenib: a meta-analysis
    • PID: 23700287, COI: 1:CAS:528:DC%2BC3sXhtFOksL3I
    • Belum VR, Wu S, Lacouture ME. Risk of hand-foot skin reaction with the novel multikinase inhibitor regorafenib: a meta-analysis. Invest New Drugs. 2013;31(4):1078–86.
    • (2013) Invest New Drugs , vol.31 , Issue.4 , pp. 1078-1086
    • Belum, V.R.1    Wu, S.2    Lacouture, M.E.3
  • 62
    • 84897575936 scopus 로고    scopus 로고
    • Cutaneous manifestations of anti-angiogenic therapy in oncology: review with focus on VEGF inhibitors
    • PID: 24355408
    • Ishak RS, Aad SA, Kyei A, Farhat FS. Cutaneous manifestations of anti-angiogenic therapy in oncology: review with focus on VEGF inhibitors. Crit Rev Oncol Hematol. 2014;90(2):152–64.
    • (2014) Crit Rev Oncol Hematol , vol.90 , Issue.2 , pp. 152-164
    • Ishak, R.S.1    Aad, S.A.2    Kyei, A.3    Farhat, F.S.4
  • 64
    • 84879089369 scopus 로고    scopus 로고
    • The risk of hand-foot skin reaction to axitinib, a novel VEGF inhibitor: a systematic review of literature and meta-analysis
    • PID: 23345001, COI: 1:CAS:528:DC%2BC3sXnt12ltb8%3D
    • Fischer A, Wu S, Ho AL, Lacouture ME. The risk of hand-foot skin reaction to axitinib, a novel VEGF inhibitor: a systematic review of literature and meta-analysis. Invest New Drugs. 2013;31(3):787–97.
    • (2013) Invest New Drugs , vol.31 , Issue.3 , pp. 787-797
    • Fischer, A.1    Wu, S.2    Ho, A.L.3    Lacouture, M.E.4
  • 65
    • 80052755557 scopus 로고    scopus 로고
    • Cutaneous toxicities of the multikinase inhibitors sorafenib and sunitinib
    • PID: 21910797
    • McLellan B, Kerr H. Cutaneous toxicities of the multikinase inhibitors sorafenib and sunitinib. Dermatol Ther. 2011;24(4):396–400.
    • (2011) Dermatol Ther , vol.24 , Issue.4 , pp. 396-400
    • McLellan, B.1    Kerr, H.2
  • 66
    • 80054827513 scopus 로고    scopus 로고
    • HFS-14, a specific quality of life scale developed for patients suffering from hand-foot syndrome
    • PID: 21964002
    • Sibaud V, Dalenc F, Chevreau C, Roche H, Delord JP, Mourey L, et al. HFS-14, a specific quality of life scale developed for patients suffering from hand-foot syndrome. Oncologist. 2011;16(10):1469–78.
    • (2011) Oncologist , vol.16 , Issue.10 , pp. 1469-1478
    • Sibaud, V.1    Dalenc, F.2    Chevreau, C.3    Roche, H.4    Delord, J.P.5    Mourey, L.6
  • 67
    • 64049100782 scopus 로고    scopus 로고
    • Search for evidence-based approaches for the prevention and palliation of hand-foot skin reaction (HFSR) caused by the multikinase inhibitors (MKIs)
    • PID: 19276294, COI: 1:CAS:528:DC%2BD1MXltFekt7g%3D
    • Anderson R, Jatoi A, Robert C, Wood LS, Keating KN, Lacouture ME. Search for evidence-based approaches for the prevention and palliation of hand-foot skin reaction (HFSR) caused by the multikinase inhibitors (MKIs). Oncologist. 2009;14(3):291–302.
    • (2009) Oncologist , vol.14 , Issue.3 , pp. 291-302
    • Anderson, R.1    Jatoi, A.2    Robert, C.3    Wood, L.S.4    Keating, K.N.5    Lacouture, M.E.6
  • 68
    • 79952281556 scopus 로고    scopus 로고
    • Experience with sorafenib and adverse event management
    • PID: 20399677
    • Bellmunt J, Eisen T, Fishman M, Quinn D. Experience with sorafenib and adverse event management. Crit Rev Oncol Hematol. 2010;78(1):24–32.
    • (2010) Crit Rev Oncol Hematol , vol.78 , Issue.1 , pp. 24-32
    • Bellmunt, J.1    Eisen, T.2    Fishman, M.3    Quinn, D.4
  • 69
    • 84857651429 scopus 로고    scopus 로고
    • Strategies for assessing and managing the adverse events of sorafenib and other targeted therapies in the treatment of renal cell and hepatocellular carcinoma: recommendations from a European nursing task group
    • PID: 21641280
    • Edmonds K, Hull D, Spencer-Shaw A, Koldenhof J, Chrysou M, Boers-Doets C, et al. Strategies for assessing and managing the adverse events of sorafenib and other targeted therapies in the treatment of renal cell and hepatocellular carcinoma: recommendations from a European nursing task group. Eur J Oncol Nurs. 2012;16(2):172–84.
    • (2012) Eur J Oncol Nurs , vol.16 , Issue.2 , pp. 172-184
    • Edmonds, K.1    Hull, D.2    Spencer-Shaw, A.3    Koldenhof, J.4    Chrysou, M.5    Boers-Doets, C.6
  • 70
    • 52949128348 scopus 로고    scopus 로고
    • Evolving strategies for the management of hand-foot skin reaction associated with the multitargeted kinase inhibitors sorafenib and sunitinib
    • PID: 18779536, COI: 1:CAS:528:DC%2BD1cXhtlaksrrP
    • Lacouture ME, Wu S, Robert C, Atkins MB, Kong HH, Guitart J, et al. Evolving strategies for the management of hand-foot skin reaction associated with the multitargeted kinase inhibitors sorafenib and sunitinib. Oncologist. 2008;13(9):1001–11.
    • (2008) Oncologist , vol.13 , Issue.9 , pp. 1001-1011
    • Lacouture, M.E.1    Wu, S.2    Robert, C.3    Atkins, M.B.4    Kong, H.H.5    Guitart, J.6
  • 71
    • 79955970528 scopus 로고    scopus 로고
    • Management of tyrosine kinase inhibitor-induced hand-foot skin reaction: viewpoints from the medical oncologist, dermatologist, and oncology nurse
    • PID: 21465734, COI: 1:CAS:528:DC%2BC3MXkt1Shsrk%3D
    • Manchen E, Robert C, Porta C. Management of tyrosine kinase inhibitor-induced hand-foot skin reaction: viewpoints from the medical oncologist, dermatologist, and oncology nurse. J Support Oncol. 2011;9(1):13–23.
    • (2011) J Support Oncol , vol.9 , Issue.1 , pp. 13-23
    • Manchen, E.1    Robert, C.2    Porta, C.3
  • 72
    • 67650113975 scopus 로고    scopus 로고
    • Array of cutaneous adverse effects associated with sorafenib
    • PID: 19615549
    • Kong HH, Turner ML. Array of cutaneous adverse effects associated with sorafenib. J Am Acad Dermatol. 2009;61(2):360–1.
    • (2009) J Am Acad Dermatol , vol.61 , Issue.2 , pp. 360-361
    • Kong, H.H.1    Turner, M.L.2
  • 73
    • 84891486967 scopus 로고    scopus 로고
    • Sunitinib adverse events in metastatic renal cell carcinoma: a meta-analysis
    • PID: 23179639, COI: 1:CAS:528:DC%2BC3sXhvFymsL%2FM
    • Ibrahim EM, Kazkaz GA, Abouelkhair KM, Bayer AM, Elmasri OA. Sunitinib adverse events in metastatic renal cell carcinoma: a meta-analysis. Int J Clin Oncol. 2013;18(6):1060–9.
    • (2013) Int J Clin Oncol , vol.18 , Issue.6 , pp. 1060-1069
    • Ibrahim, E.M.1    Kazkaz, G.A.2    Abouelkhair, K.M.3    Bayer, A.M.4    Elmasri, O.A.5
  • 75
    • 77956649079 scopus 로고    scopus 로고
    • A Phase II, open-label study evaluating pazopanib in patients with recurrent ovarian cancer
    • PID: 20584542, COI: 1:CAS:528:DC%2BC3cXhtFClsbjK
    • Friedlander M, Hancock KC, Rischin D, Messing MJ, Stringer CA, Matthys GM, et al. A Phase II, open-label study evaluating pazopanib in patients with recurrent ovarian cancer. Gynecol Oncol. 2010;119(1):32–7.
    • (2010) Gynecol Oncol , vol.119 , Issue.1 , pp. 32-37
    • Friedlander, M.1    Hancock, K.C.2    Rischin, D.3    Messing, M.J.4    Stringer, C.A.5    Matthys, G.M.6
  • 77
    • 84871361940 scopus 로고    scopus 로고
    • A new spectrum of skin toxic effects associated with the multikinase inhibitor vandetanib
    • PID: 23247489
    • Giacchero D, Ramacciotti C, Arnault JP, Brassard M, Baudin E, Maksimovic L, et al. A new spectrum of skin toxic effects associated with the multikinase inhibitor vandetanib. Arch Dermatol. 2012;148(12):1418–20.
    • (2012) Arch Dermatol , vol.148 , Issue.12 , pp. 1418-1420
    • Giacchero, D.1    Ramacciotti, C.2    Arnault, J.P.3    Brassard, M.4    Baudin, E.5    Maksimovic, L.6
  • 78
    • 80755175261 scopus 로고    scopus 로고
    • Dermatologic side effects induced by new angiogenesis inhibitors
    • PID: 22001771
    • Sibaud V, Garrido-Stowhas I, Cottura E, Chevreau C. Dermatologic side effects induced by new angiogenesis inhibitors. Bull Cancer. 2011;98(10):1221–9.
    • (2011) Bull Cancer , vol.98 , Issue.10 , pp. 1221-1229
    • Sibaud, V.1    Garrido-Stowhas, I.2    Cottura, E.3    Chevreau, C.4
  • 79
    • 50449100624 scopus 로고    scopus 로고
    • Scrotal cutaneous side effects of sunitinib
    • PID: 18753659, COI: 1:CAS:528:DC%2BD1cXhtVGms7rO, (discussion 6)
    • Billemont B, Barete S, Rixe O. Scrotal cutaneous side effects of sunitinib. N Engl J Med. 2008;359(9):975–6 (discussion 6).
    • (2008) N Engl J Med , vol.359 , Issue.9 , pp. 975-976
    • Billemont, B.1    Barete, S.2    Rixe, O.3
  • 80
    • 84872339660 scopus 로고    scopus 로고
    • The price of tumor control: an analysis of rare side effects of anti-CTLA-4 therapy in metastatic melanoma from the ipilimumab network
    • PID: 23341990, COI: 1:CAS:528:DC%2BC3sXhsVGmurc%3D
    • Voskens CJ, Goldinger SM, Loquai C, Robert C, Kaehler KC, Berking C, et al. The price of tumor control: an analysis of rare side effects of anti-CTLA-4 therapy in metastatic melanoma from the ipilimumab network. PLoS One. 2013;8(1):e53745.
    • (2013) PLoS One , vol.8 , Issue.1 , pp. e53745
    • Voskens, C.J.1    Goldinger, S.M.2    Loquai, C.3    Robert, C.4    Kaehler, K.C.5    Berking, C.6
  • 81
    • 84864052441 scopus 로고    scopus 로고
    • Management of immune-related adverse events and kinetics of response with ipilimumab
    • PID: 22614989, COI: 1:CAS:528:DC%2BC38Xht1ygsr%2FK
    • Weber JS, Kahler KC, Hauschild A. Management of immune-related adverse events and kinetics of response with ipilimumab. J Clin Oncol. 2012;30(21):2691–7.
    • (2012) J Clin Oncol , vol.30 , Issue.21 , pp. 2691-2697
    • Weber, J.S.1    Kahler, K.C.2    Hauschild, A.3
  • 82
    • 84890796086 scopus 로고    scopus 로고
    • Expanded access study of patients with advanced basal cell carcinoma treated with the Hedgehog pathway inhibitor, vismodegib
    • PID: 24189279, COI: 1:CAS:528:DC%2BC3sXhslaqsrvL
    • Chang AL, Solomon JA, Hainsworth JD, Goldberg L, McKenna E, Day BM, et al. Expanded access study of patients with advanced basal cell carcinoma treated with the Hedgehog pathway inhibitor, vismodegib. J Am Acad Dermatol. 2014;70(1):60–9.
    • (2014) J Am Acad Dermatol , vol.70 , Issue.1 , pp. 60-69
    • Chang, A.L.1    Solomon, J.A.2    Hainsworth, J.D.3    Goldberg, L.4    McKenna, E.5    Day, B.M.6
  • 83
    • 84887066721 scopus 로고    scopus 로고
    • GDC-0449 in patients with advanced chondrosarcomas: a French Sarcoma Group/US and French National Cancer Institute Single-Arm Phase II Collaborative Study
    • PID: 24170610, COI: 1:STN:280:DC%2BC2c7gvFyjtg%3D%3D
    • Italiano A, Le Cesne A, Bellera C, Piperno-Neumann S, Duffaud F, Penel N, et al. GDC-0449 in patients with advanced chondrosarcomas: a French Sarcoma Group/US and French National Cancer Institute Single-Arm Phase II Collaborative Study. Ann Oncol. 2013;24(11):2922–6.
    • (2013) Ann Oncol , vol.24 , Issue.11 , pp. 2922-2926
    • Italiano, A.1    Le Cesne, A.2    Bellera, C.3    Piperno-Neumann, S.4    Duffaud, F.5    Penel, N.6
  • 84
    • 79954611501 scopus 로고    scopus 로고
    • Phase I trial of hedgehog pathway inhibitor vismodegib (GDC-0449) in patients with refractory, locally advanced or metastatic solid tumors
    • PID: 21300762, COI: 1:CAS:528:DC%2BC3MXkslCgt7Y%3D
    • LoRusso PM, Rudin CM, Reddy JC, Tibes R, Weiss GJ, Borad MJ, et al. Phase I trial of hedgehog pathway inhibitor vismodegib (GDC-0449) in patients with refractory, locally advanced or metastatic solid tumors. Clin Cancer Res. 2011;17(8):2502–11.
    • (2011) Clin Cancer Res , vol.17 , Issue.8 , pp. 2502-2511
    • LoRusso, P.M.1    Rudin, C.M.2    Reddy, J.C.3    Tibes, R.4    Weiss, G.J.5    Borad, M.J.6
  • 85
    • 84891872634 scopus 로고    scopus 로고
    • Life-threatening dermatologic adverse events in oncology
    • PID: 24108082, COI: 1:CAS:528:DC%2BC3sXhvFOms7jJ
    • Rosen AC, Balagula Y, Raisch DW, Garg V, Nardone B, Larsen N, et al. Life-threatening dermatologic adverse events in oncology. Anticancer Drugs. 2014;25(2):225–34.
    • (2014) Anticancer Drugs , vol.25 , Issue.2 , pp. 225-234
    • Rosen, A.C.1    Balagula, Y.2    Raisch, D.W.3    Garg, V.4    Nardone, B.5    Larsen, N.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.