-
1
-
-
77950516104
-
MTOR signaling and drug development in cancer
-
Dancey J,. mTOR signaling and drug development in cancer. Nat Rev Clin Oncol. 2010; 7: 209-219.
-
(2010)
Nat Rev Clin Oncol.
, vol.7
, pp. 209-219
-
-
Dancey, J.1
-
2
-
-
67349127898
-
The emerging safety profile of mTOR inhibitors, a novel class of anticancer agents
-
Sankhala K, Mita A, Kelly K, Mahalingam D, Giles F, Mita M,. The emerging safety profile of mTOR inhibitors, a novel class of anticancer agents. Target Oncol. 2009; 4: 135-142.
-
(2009)
Target Oncol.
, vol.4
, pp. 135-142
-
-
Sankhala, K.1
Mita, A.2
Kelly, K.3
Mahalingam, D.4
Giles, F.5
Mita, M.6
-
3
-
-
48649107474
-
Efficacy of everolimus in advanced renal cell carcinoma: A double-blind, randomised, placebo-controlled phase III trial
-
Motzer RJ, Escudier B, Oudard S, et al. Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial. Lancet. 2008; 372: 449-456.
-
(2008)
Lancet.
, vol.372
, pp. 449-456
-
-
Motzer, R.J.1
Escudier, B.2
Oudard, S.3
-
4
-
-
84856212971
-
The risk of skin rash and stomatitis with the mammalian target of rapamycin inhibitor temsirolimus: A systematic review of the literature and meta-analysis
-
Gomez-Fernandez C, Garden BC, Wu S, Feldman DR, Lacouture ME,. The risk of skin rash and stomatitis with the mammalian target of rapamycin inhibitor temsirolimus: A systematic review of the literature and meta-analysis. Eur J Cancer. 2012; 48: 340-346.
-
(2012)
Eur J Cancer.
, vol.48
, pp. 340-346
-
-
Gomez-Fernandez, C.1
Garden, B.C.2
Wu, S.3
Feldman, D.R.4
Lacouture, M.E.5
-
5
-
-
33745006874
-
Acne in recipients of renal transplantation treated with sirolimus: Clinical, microbiologic, histologic, therapeutic, and pathogenic aspects
-
Mahe E, Morelon E, Lechaton S, et al. Acne in recipients of renal transplantation treated with sirolimus: clinical, microbiologic, histologic, therapeutic, and pathogenic aspects. J Am Acad Dermatol. 2006; 55: 139-142.
-
(2006)
J Am Acad Dermatol.
, vol.55
, pp. 139-142
-
-
Mahe, E.1
Morelon, E.2
Lechaton, S.3
-
6
-
-
33750558062
-
Skin rash secondary to bevacizumab in a patient with advanced colorectal cancer and relation to response
-
Gotlib V, Khaled S, Lapko I, Mar N, Saif MW,. Skin rash secondary to bevacizumab in a patient with advanced colorectal cancer and relation to response. Anticancer Drugs. 2006; 17: 1227-1229.
-
(2006)
Anticancer Drugs.
, vol.17
, pp. 1227-1229
-
-
Gotlib, V.1
Khaled, S.2
Lapko, I.3
Mar, N.4
Saif, M.W.5
-
7
-
-
0027309532
-
Stevens-Johnson syndrome associated with methotrexate treatment for non-Hodgkin's lymphoma
-
Cuthbert RJ, Craig JI, Ludlam CA,. Stevens-Johnson syndrome associated with methotrexate treatment for non-Hodgkin's lymphoma. Ulster Med J. 1993; 62: 95-97.
-
(1993)
Ulster Med J.
, vol.62
, pp. 95-97
-
-
Cuthbert, R.J.1
Craig, J.I.2
Ludlam, C.A.3
-
8
-
-
77952905485
-
MTOR inhibitor-associated dermatologic and mucosal problems
-
Campistol JM, de Fijter JW, Flechner SM, Langone A, Morelon E, Stockfleth E,. mTOR inhibitor-associated dermatologic and mucosal problems. Clin Transplant. 2010; 24: 149-156.
-
(2010)
Clin Transplant.
, vol.24
, pp. 149-156
-
-
Campistol, J.M.1
De Fijter, J.W.2
Flechner, S.M.3
Langone, A.4
Morelon, E.5
Stockfleth, E.6
-
9
-
-
2942735384
-
Safety and pharmacokinetics of escalated doses of weekly intravenous infusion of CCI-779, a novel mTOR inhibitor, in patients with cancer
-
Raymond E, Alexandre J, Faivre S, et al. Safety and pharmacokinetics of escalated doses of weekly intravenous infusion of CCI-779, a novel mTOR inhibitor, in patients with cancer. J Clin Oncol. 2004; 22: 2336-2347.
-
(2004)
J Clin Oncol.
, vol.22
, pp. 2336-2347
-
-
Raymond, E.1
Alexandre, J.2
Faivre, S.3
-
10
-
-
80555126830
-
Phase 1/2 study of everolimus in advanced hepatocellular carcinoma
-
Zhu AX, Abrams TA, Miksad R, et al. Phase 1/2 study of everolimus in advanced hepatocellular carcinoma. Cancer. 2011; 117: 5094-5102.
-
(2011)
Cancer.
, vol.117
, pp. 5094-5102
-
-
Zhu, A.X.1
Abrams, T.A.2
Miksad, R.3
-
11
-
-
43249086546
-
Phase i pharmacokinetic and pharmacodynamic study of the oral mammalian target of rapamycin inhibitor everolimus in patients with advanced solid tumors
-
O'Donnell A, Faivre S, Burris HA 3rd, et al. Phase I pharmacokinetic and pharmacodynamic study of the oral mammalian target of rapamycin inhibitor everolimus in patients with advanced solid tumors. J Clin Oncol. 2008; 26: 1588-1595.
-
(2008)
J Clin Oncol.
, vol.26
, pp. 1588-1595
-
-
O'Donnell, A.1
Faivre, S.2
Burris III, H.A.3
-
12
-
-
43249131245
-
Dose- and schedule-dependent inhibition of the mammalian target of rapamycin pathway with everolimus: A phase i tumor pharmacodynamic study in patients with advanced solid tumors
-
Tabernero J, Rojo F, Calvo E, et al. Dose- and schedule-dependent inhibition of the mammalian target of rapamycin pathway with everolimus: a phase I tumor pharmacodynamic study in patients with advanced solid tumors. J Clin Oncol. 2008; 26: 1603-1610.
-
(2008)
J Clin Oncol.
, vol.26
, pp. 1603-1610
-
-
Tabernero, J.1
Rojo, F.2
Calvo, E.3
-
13
-
-
26944467607
-
The management of skin reactions in cancer patients receiving epidermal growth factor receptor targeted therapies
-
Segaert S, Tabernero J, Chosidow O, et al. The management of skin reactions in cancer patients receiving epidermal growth factor receptor targeted therapies. J Dtsch Dermatol Ges. 2005; 3: 599-606.
-
(2005)
J Dtsch Dermatol Ges.
, vol.3
, pp. 599-606
-
-
Segaert, S.1
Tabernero, J.2
Chosidow, O.3
-
14
-
-
20044379939
-
Cutaneous adverse events in renal transplant recipients receiving sirolimus-based therapy
-
Mahe E, Morelon E, Lechaton S, et al. Cutaneous adverse events in renal transplant recipients receiving sirolimus-based therapy. Transplantation. 2005; 79: 476-482.
-
(2005)
Transplantation.
, vol.79
, pp. 476-482
-
-
Mahe, E.1
Morelon, E.2
Lechaton, S.3
-
16
-
-
0141679203
-
Involvement of the Akt/mTOR pathway on EGF-induced cell transformation
-
Nomura M, He Z, Koyama I, Ma WY, Miyamoto K, Dong Z,. Involvement of the Akt/mTOR pathway on EGF-induced cell transformation. Mol Carcinog. 2003; 38: 25-32.
-
(2003)
Mol Carcinog.
, vol.38
, pp. 25-32
-
-
Nomura, M.1
He, Z.2
Koyama, I.3
Ma, W.Y.4
Miyamoto, K.5
Dong, Z.6
-
17
-
-
33745003902
-
A keratin cytoskeletal protein regulates protein synthesis and epithelial cell growth
-
Kim S, Wong P, Coulombe PA,. A keratin cytoskeletal protein regulates protein synthesis and epithelial cell growth. Nature. 2006; 441: 362-365.
-
(2006)
Nature.
, vol.441
, pp. 362-365
-
-
Kim, S.1
Wong, P.2
Coulombe, P.A.3
-
18
-
-
24644513947
-
Cutaneous adverse effects with HER1/EGFR-targeted agents: Is there a silver lining?
-
Perez-Soler R, Saltz L,. Cutaneous adverse effects with HER1/EGFR-targeted agents: is there a silver lining? J Clin Oncol. 2005; 23: 5235-5246.
-
(2005)
J Clin Oncol.
, vol.23
, pp. 5235-5246
-
-
Perez-Soler, R.1
Saltz, L.2
|