-
1
-
-
76749111911
-
Effect of cytochrome P450 polymorphism on arachidonic acid metabolism and their impact on cardiovascular diseases
-
Zordoky, B. N., and A. O. El-Kadi. 2010. Effect of cytochrome P450 polymorphism on arachidonic acid metabolism and their impact on cardiovascular diseases. Pharmacol. Ther. 125: 446-463.
-
(2010)
Pharmacol. Ther.
, vol.125
, pp. 446-463
-
-
Zordoky, B.N.1
El-Kadi, A.O.2
-
2
-
-
78649451203
-
Role of cytochrome P450 enzymes in the bioactivation of polyunsaturated fatty acids
-
Konkel, A., and W. H. Schunck. 2011. Role of cytochrome P450 enzymes in the bioactivation of polyunsaturated fatty acids. Biochim. Biophys. Acta. 1814: 210-222.
-
(2011)
Biochim. Biophys. Acta
, vol.1814
, pp. 210-222
-
-
Konkel, A.1
Schunck, W.H.2
-
3
-
-
77955419553
-
Genetic polymorphism of CYP2U1, a cytochrome P450 involved in fatty acids hydroxylation
-
Devos, A., C. L. Lino Cardenas, F. Glowacki, A. Engels, J. M. Lo-Guidice, D. Chevalier, D. Allorge, F. Broly, and C. Cauffiez. 2010. Genetic polymorphism of CYP2U1, a cytochrome P450 involved in fatty acids hydroxylation. Prostaglandins Leukot. Essent. Fatty Acids. 83: 105-110.
-
(2010)
Prostaglandins Leukot. Essent. Fatty Acids
, vol.83
, pp. 105-110
-
-
Devos, A.1
Lino Cardenas, C.L.2
Glowacki, F.3
Engels, A.4
Lo-Guidice, J.M.5
Chevalier, D.6
Allorge, D.7
Broly, F.8
Cauffiez, C.9
-
4
-
-
27744551500
-
Role of 20-hydroxyeicosatetraenoic acid (20-HETE) in vascular system
-
Miyata, N., and R. J. Roman. 2005. Role of 20-hydroxyeicosatetraenoic acid (20-HETE) in vascular system. J. Smooth Muscle Res. 41: 175-193.
-
(2005)
J. Smooth Muscle Res.
, vol.41
, pp. 175-193
-
-
Miyata, N.1
Roman, R.J.2
-
6
-
-
78049297452
-
Metabolic profiling of murine plasma reveals an unexpected biomarker in rofecoxib-mediated cardiovascular events
-
Liu, J. Y., N. Li, J. Yang, H. Qiu, D. Ai, N. Chiamvimonvat, Y. Zhu, and B. D. Hammock. 2010. Metabolic profiling of murine plasma reveals an unexpected biomarker in rofecoxib-mediated cardiovascular events. Proc. Natl. Acad. Sci. USA. 107: 17017-17022.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 17017-17022
-
-
Liu, J.Y.1
Li, N.2
Yang, J.3
Qiu, H.4
Ai, D.5
Chiamvimonvat, N.6
Zhu, Y.7
Hammock, B.D.8
-
7
-
-
14144256771
-
20-HETE-mediated vasoconstriction by hemoglobin-O2 carrier in Sprague-Dawley but not Wistar rats
-
Baines, A. D., and P. Ho. 2005. 20-HETE-mediated vasoconstriction by hemoglobin-O2 carrier in Sprague-Dawley but not Wistar rats. J. Appl. Physiol. 98: 772-779.
-
(2005)
J. Appl. Physiol.
, vol.98
, pp. 772-779
-
-
Baines, A.D.1
Ho, P.2
-
8
-
-
83555164823
-
Testosterone-dependent increase in blood pressure is mediated by elevated Cyp4A expression in fructose-fed rats
-
Vasudevan, H., V. G. Yuen, and J. H. McNeill. 2012. Testosterone-dependent increase in blood pressure is mediated by elevated Cyp4A expression in fructose-fed rats. Mol. Cell. Biochem. 359: 409-418.
-
(2012)
Mol. Cell. Biochem.
, vol.359
, pp. 409-418
-
-
Vasudevan, H.1
Yuen, V.G.2
McNeill, J.H.3
-
9
-
-
3342875746
-
Urinary 20-hydroxyeicosatetraenoic acid is associated with endothelial dysfunction in humans
-
Ward, N. C., J. Rivera, J. Hodgson, I. B. Puddey, L. J. Beilin, J. R. Falck, and K. D. Croft. 2004. Urinary 20-hydroxyeicosatetraenoic acid is associated with endothelial dysfunction in humans. Circulation. 110: 438-443.
-
(2004)
Circulation
, vol.110
, pp. 438-443
-
-
Ward, N.C.1
Rivera, J.2
Hodgson, J.3
Puddey, I.B.4
Beilin, L.J.5
Falck, J.R.6
Croft, K.D.7
-
10
-
-
31944441144
-
Association of the T8590C polymorphism of CYP4A11 with hypertension in the MONICA Augsburg echocardiographic substudy
-
Mayer, B., W. Lieb, A. Gotz, I. R. Konig, Z. Aherrahrou, A. Thiemig, S. Holmer, C. Hengstenberg, A. Doering, H. Loewel, et al. 2005. Association of the T8590C polymorphism of CYP4A11 with hypertension in the MONICA Augsburg echocardiographic substudy. Hypertension. 46: 766-771.
-
(2005)
Hypertension
, vol.46
, pp. 766-771
-
-
Mayer, B.1
Lieb, W.2
Gotz, A.3
Konig, I.R.4
Aherrahrou, Z.5
Thiemig, A.6
Holmer, S.7
Hengstenberg, C.8
Doering, A.9
Loewel, H.10
-
11
-
-
44349119245
-
Association of a functional cytochrome P450 4F2 haplotype with urinary 20-HETE and hypertension
-
Liu, H., Y. Zhao, D. Nie, J. Shi, L. Fu, Y. Li, D. Yu, and J. Lu. 2008. Association of a functional cytochrome P450 4F2 haplotype with urinary 20-HETE and hypertension. J. Am. Soc. Nephrol. 19: 714-721.
-
(2008)
J. Am. Soc. Nephrol
, vol.19
, pp. 714-721
-
-
Liu, H.1
Zhao, Y.2
Nie, D.3
Shi, J.4
Fu, L.5
Li, Y.6
Yu, D.7
Lu, J.8
-
12
-
-
77958461840
-
20-Hydroxyeicosatetraeonic acid: A new target for the treatment of hypertension
-
Williams, J. M., S. Murphy, M. Burke, and R. J. Roman. 2010. 20-hydroxyeicosatetraeonic acid: a new target for the treatment of hypertension. J. Cardiovasc. Pharmacol. 56: 336-344.
-
(2010)
J. Cardiovasc. Pharmacol.
, vol.56
, pp. 336-344
-
-
Williams, J.M.1
Murphy, S.2
Burke, M.3
Roman, R.J.4
-
13
-
-
0034112394
-
Determination of free and glucuronide conjugated 20-hydroxyarachidonic acid (20-HETE) in urine by gas chromatography/negative ion chemical ionization mass spectrometry
-
Watzer, B., S. Reinalter, H. W. Seyberth, and H. Schweer. 2000. Determination of free and glucuronide conjugated 20-hydroxyarachidonic acid (20-HETE) in urine by gas chromatography/negative ion chemical ionization mass spectrometry. Prostaglandins Leukot. Essent. Fatty Acids. 62: 175-181.
-
(2000)
Prostaglandins Leukot. Essent. Fatty Acids
, vol.62
, pp. 175-181
-
-
Watzer, B.1
Reinalter, S.2
Seyberth, H.W.3
Schweer, H.4
-
14
-
-
15244348288
-
Urinary 20-hydroxyeicosatetraenoic acid excretion is associated with oxidative stress in hypertensive subjects
-
Ward, N. C., I. B. Puddey, J. M. Hodgson, L. J. Beilin, and K. D. Croft. 2005. Urinary 20-hydroxyeicosatetraenoic acid excretion is associated with oxidative stress in hypertensive subjects. Free Radic. Biol. Med. 38: 1032-1036.
-
(2005)
Free Radic. Biol. Med.
, vol.38
, pp. 1032-1036
-
-
Ward, N.C.1
Puddey, I.B.2
Hodgson, J.M.3
Beilin, L.J.4
Croft, K.D.5
-
15
-
-
80051629820
-
20-Hydroxyeicosatetraenoic acid, endothelial dysfunction and hypertension
-
Pat Kunert, M., and I. Drenjancevic. 2011. 20-Hydroxyeicosatetraenoic acid, endothelial dysfunction and hypertension. Med. Glas. (Zenica). 8: 170-180.
-
(2011)
Med. Glas. (Zenica)
, vol.8
, pp. 170-180
-
-
Pat Kunert, M.1
Drenjancevic, I.2
-
16
-
-
33847041486
-
Elevations in renal interstitial hydrostatic pressure and 20-hydroxyeicosatetraenoic acid contribute to pressure natriuresis
-
Williams, J. M., A. Sarkis, B. Lopez, R. P. Ryan, A. K. Flasch, and R. J. Roman. 2007. Elevations in renal interstitial hydrostatic pressure and 20-hydroxyeicosatetraenoic acid contribute to pressure natriuresis. Hypertension. 49: 687-694.
-
(2007)
Hypertension
, vol.49
, pp. 687-694
-
-
Williams, J.M.1
Sarkis, A.2
Lopez, B.3
Ryan, R.P.4
Flasch, A.K.5
Roman, R.J.6
-
18
-
-
0034128936
-
Human UDP-glucuronosyltransferases: Metabolism, expression, and disease
-
Tukey, R. H., and C. P. Strassburg. 2000. Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annu. Rev. Pharmacol. Toxicol. 40: 581-616.
-
(2000)
Annu. Rev. Pharmacol. Toxicol.
, vol.40
, pp. 581-616
-
-
Tukey, R.H.1
Strassburg, C.P.2
-
19
-
-
74549132748
-
Interindividual variability in hepatic drug glucuronidation: Studies into the role of age, sex, enzyme inducers, and genetic polymorphism using the human liver bank as a model system
-
Court, M. H. 2010. Interindividual variability in hepatic drug glucuronidation: studies into the role of age, sex, enzyme inducers, and genetic polymorphism using the human liver bank as a model system. Drug Metab. Rev. 42: 209-224.
-
(2010)
Drug Metab. Rev.
, vol.42
, pp. 209-224
-
-
Court, M.H.1
-
20
-
-
0037819284
-
Pharmacogenomics of human UDP-glucuronosyltransferase enzymes
-
Guillemette, C. 2003. Pharmacogenomics of human UDP-glucuronosyltransferase enzymes. Pharmacogenomics J. 3: 136-158.
-
(2003)
Pharmacogenomics J
, vol.3
, pp. 136-158
-
-
Guillemette, C.1
-
21
-
-
0142074253
-
Glucuronidation of arachidonic and linoleic acid metabolites by human UDP-glucuronosyltransferases
-
Turgeon, D., S. Chouinard, P. Belanger, S. Picard, J. F. Labbe, P. Borgeat, and A. Belanger. 2003. Glucuronidation of arachidonic and linoleic acid metabolites by human UDP-glucuronosyltransferases. J. Lipid Res. 44: 1182-1191.
-
(2003)
J. Lipid Res.
, vol.44
, pp. 1182-1191
-
-
Turgeon, D.1
Chouinard, S.2
Belanger, P.3
Picard, S.4
Labbe, J.F.5
Borgeat, P.6
Belanger, A.7
-
22
-
-
67649401803
-
Discovery of novel functional variants and extensive evaluation of CYP2D6 genetic polymorphisms in Koreans
-
Lee, S. J., S. S. Lee, H. J. Jung, H. S. Kim, S. J. Park, C. W. Yeo, and J. G. Shin. 2009. Discovery of novel functional variants and extensive evaluation of CYP2D6 genetic polymorphisms in Koreans. Drug Metab. Dispos. 37: 1464-1470.
-
(2009)
Drug Metab. Dispos
, vol.37
, pp. 1464-1470
-
-
Lee, S.J.1
Lee, S.S.2
Jung, H.J.3
Kim, H.S.4
Park, S.J.5
Yeo, C.W.6
Shin, J.G.7
-
23
-
-
78049364078
-
Metabolism of 1′- and 4-hydroxymidazolam by glucuronide conjugation is largely mediated by UDP-glucuronosyltransferases 1A4, 2B4, and 2B7
-
Seo, K. A., S. K. Bae, Y. K. Choi, C. S. Choi, K. H. Liu, and J. G. Shin. 2010. Metabolism of 1′- and 4-hydroxymidazolam by glucuronide conjugation is largely mediated by UDP-glucuronosyltransferases 1A4, 2B4, and 2B7. Drug Metab. Dispos. 38: 2007-2013.
-
(2010)
Drug Metab. Dispos
, vol.38
, pp. 2007-2013
-
-
Seo, K.A.1
Bae, S.K.2
Choi, Y.K.3
Choi, C.S.4
Liu, K.H.5
Shin, J.G.6
-
24
-
-
4644315738
-
Glucuronidation of oxidized fatty acids and prostaglandins B1 and E2 by human hepatic and recombinant UDP-glucuronosyltransferases
-
Little, J. M., M. Kurkela, J. Sonka, S. Jantti, R. Ketola, S. Bratton, M. Finel, and A. Radominska-Pandya. 2004. Glucuronidation of oxidized fatty acids and prostaglandins B1 and E2 by human hepatic and recombinant UDP-glucuronosyltransferases. J. Lipid Res. 45: 1694-1703.
-
(2004)
J. Lipid Res.
, vol.45
, pp. 1694-1703
-
-
Little, J.M.1
Kurkela, M.2
Sonka, J.3
Jantti, S.4
Ketola, R.5
Bratton, S.6
Finel, M.7
Radominska-Pandya, A.8
-
25
-
-
0035038561
-
Characterization of rat and human UDP-glucuronosyltransferases responsible for the in vitro glucuronidation of diclofenac
-
King, C., W. Tang, J. Ngui, T. Tephly, and M. Braun. 2001. Characterization of rat and human UDP-glucuronosyltransferases responsible for the in vitro glucuronidation of diclofenac. Toxicol. Sci. 61: 49-53.
-
(2001)
Toxicol. Sci.
, vol.61
, pp. 49-53
-
-
King, C.1
Tang, W.2
Ngui, J.3
Tephly, T.4
Braun, M.5
-
26
-
-
33747847155
-
Genetic variants of human UGT1A3: Functional characterization and frequency distribution in a Chinese Han population
-
Chen, Y., S. Chen, X. Li, X. Wang, and S. Zeng. 2006. Genetic variants of human UGT1A3: functional characterization and frequency distribution in a Chinese Han population. Drug Metab. Dispos. 34: 1462-1467.
-
(2006)
Drug Metab. Dispos
, vol.34
, pp. 1462-1467
-
-
Chen, Y.1
Chen, S.2
Li, X.3
Wang, X.4
Zeng, S.5
-
27
-
-
77956948166
-
Genetic variations in UDP-glucuronosyltransferase 2B7 gene (UGT2B7) in a Korean population
-
Hwang, M. S., S. J. Lee, H. E. Jeong, S. Lee, M. A. Yoo, and J. G. Shin. 2010. Genetic variations in UDP-glucuronosyltransferase 2B7 gene (UGT2B7) in a Korean population. Drug Metab. Pharmacokinet. 25: 398-402.
-
(2010)
Drug Metab. Pharmacokinet
, vol.25
, pp. 398-402
-
-
Hwang, M.S.1
Lee, S.J.2
Jeong, H.E.3
Lee, S.4
Yoo, M.A.5
Shin, J.G.6
-
28
-
-
38549129869
-
Genetic variations and haplotypes of UDP-glucuronosyltransferase 1A locus in a Korean population
-
Yea, S. S., S. S. Lee, W. Y. Kim, K. H. Liu, H. Kim, J. H. Shon, I. J. Cha, and J. G. Shin. 2008. Genetic variations and haplotypes of UDP-glucuronosyltransferase 1A locus in a Korean population. Ther. Drug Monit. 30: 23-34.
-
(2008)
Ther. Drug Monit
, vol.30
, pp. 23-34
-
-
Yea, S.S.1
Lee, S.S.2
Kim, W.Y.3
Liu, K.H.4
Kim, H.5
Shon, J.H.6
Cha, I.J.7
Shin, J.G.8
-
29
-
-
59749087186
-
Close association of UGT1A9 IVS1+399C>T with UGT1A1∗28, ∗6, or ∗60 haplotype and its apparent influence on 7-ethyl-10-hydroxycamptothecin (SN-38) glucuronidation in Japanese
-
Saito, Y., K. Sai, K. Maekawa, N. Kaniwa, K. Shirao, T. Hamaguchi, N. Yamamoto, H. Kunitoh, Y. Ohe, Y. Yamada, et al. 2009. Close association of UGT1A9 IVS1+399C>T with UGT1A1∗28, ∗6, or ∗60 haplotype and its apparent influence on 7-ethyl-10-hydroxycamptothecin (SN-38) glucuronidation in Japanese. Drug Metab. Dispos. 37: 272-276.
-
(2009)
Drug Metab. Dispos
, vol.37
, pp. 272-276
-
-
Saito, Y.1
Sai, K.2
Maekawa, K.3
Kaniwa, N.4
Shirao, K.5
Hamaguchi, T.6
Yamamoto, N.7
Kunitoh, H.8
Ohe, Y.9
Yamada, Y.10
-
30
-
-
33745242349
-
The novel UGT1A9 intronic I399 polymorphism appears as a predictor of 7-ethyl-10-hydroxycamptothecin glucuronidation levels in the liver
-
Girard, H., L. Villeneuve, M. H. Court, L. C. Fortier, P. Caron, Q. Hao, L. L. von Moltke, D. J. Greenblatt, and C. Guillemette. 2006. The novel UGT1A9 intronic I399 polymorphism appears as a predictor of 7-ethyl-10-hydroxycamptothecin glucuronidation levels in the liver. Drug Metab. Dispos. 34: 1220-1228.
-
(2006)
Drug Metab. Dispos
, vol.34
, pp. 1220-1228
-
-
Girard, H.1
Villeneuve, L.2
Court, M.H.3
Fortier, L.C.4
Caron, P.5
Hao, Q.6
Von Moltke, L.L.7
Greenblatt, D.J.8
Guillemette, C.9
-
31
-
-
0030924008
-
Eicosanoid excretion in hepatic cirrhosis. Predominance of 20-HETE
-
Sacerdoti, D., M. Balazy, P. Angeli, A. Gatta, and J. C. McGiff. 1997. Eicosanoid excretion in hepatic cirrhosis. Predominance of 20-HETE. J. Clin. Invest. 100: 1264-1270.
-
(1997)
J. Clin. Invest.
, vol.100
, pp. 1264-1270
-
-
Sacerdoti, D.1
Balazy, M.2
Angeli, P.3
Gatta, A.4
McGiff, J.C.5
-
32
-
-
0029930148
-
UDP glucuronosyltransferase in the cirrhotic rat liver
-
Debinski, H. S., P. I. Mackenzie, C. S. Lee, M. L. Mashford, J. A. Danks, T. R. Tephly, M. Green, and P. V. Desmond. 1996. UDP glucuronosyltransferase in the cirrhotic rat liver. J. Gastroenterol. Hepatol. 11: 373-379.
-
(1996)
J. Gastroenterol. Hepatol.
, vol.11
, pp. 373-379
-
-
Debinski, H.S.1
Mackenzie, P.I.2
Lee, C.S.3
Mashford, M.L.4
Danks, J.A.5
Tephly, T.R.6
Green, M.7
Desmond, P.V.8
-
33
-
-
2442547653
-
A novel polymorphism in the promoter region of human UGT1A9 gene (UGT1A9∗22) and its effects on the transcriptional activity
-
Yamanaka, H., M. Nakajima, M. Katoh, Y. Hara, O. Tachibana, J. Yamashita, H. L. McLeod, and T. Yokoi. 2004. A novel polymorphism in the promoter region of human UGT1A9 gene (UGT1A9∗22) and its effects on the transcriptional activity. Pharmacogenetics. 14: 329-332.
-
(2004)
Pharmacogenetics
, vol.14
, pp. 329-332
-
-
Yamanaka, H.1
Nakajima, M.2
Katoh, M.3
Hara, Y.4
Tachibana, O.5
Yamashita, J.6
McLeod, H.L.7
Yokoi, T.8
-
34
-
-
31544450520
-
Characterization of common UGT1A8, UGT1A9, and UGT2B7 variants with different capacities to inactivate mutagenic 4-hydroxylated metabolites of estradiol and estrone
-
Thibaudeau, J., J. Lepine, J. Tojcic, Y. Duguay, G. Pelletier, M. Plante, J. Brisson, B. Tetu, S. Jacob, L. Perusse, et al. 2006. Characterization of common UGT1A8, UGT1A9, and UGT2B7 variants with different capacities to inactivate mutagenic 4-hydroxylated metabolites of estradiol and estrone. Cancer Res. 66: 125-133.
-
(2006)
Cancer Res.
, vol.66
, pp. 125-133
-
-
Thibaudeau, J.1
Lepine, J.2
Tojcic, J.3
Duguay, Y.4
Pelletier, G.5
Plante, M.6
Brisson, J.7
Tetu, B.8
Jacob, S.9
Perusse, L.10
-
35
-
-
84860389261
-
Impact of UGT2B7 His268Tyr polymorphism on the outcome of adjuvant epirubicin treatment in breast cancer
-
Parmar, S., J. C. Stingl, A. Huber-Wechselberger, A. Kainz, W. Renner, U. Langsenlehner, P. Krippl, J. Brockmoller, and E. Haschke-Becher. 2011. Impact of UGT2B7 His268Tyr polymorphism on the outcome of adjuvant epirubicin treatment in breast cancer. Breast Cancer Res. 13: R57.
-
(2011)
Breast Cancer Res.
, vol.13
, pp. R57
-
-
Parmar, S.1
Stingl, J.C.2
Huber-Wechselberger, A.3
Kainz, A.4
Renner, W.5
Langsenlehner, U.6
Krippl, P.7
Brockmoller, J.8
Haschke-Becher, E.9
-
36
-
-
33846230114
-
Genetic susceptibility to diclofenac-induced hepatotoxicity: Contribution of UGT2B7, CYP2C8, and ABCC2 genotypes
-
Daly, A. K., G. P. Aithal, J. B. Leathart, R. A. Swainsbury, T. S. Dang, and C. P. Day. 2007. Genetic susceptibility to diclofenac-induced hepatotoxicity: contribution of UGT2B7, CYP2C8, and ABCC2 genotypes. Gastroenterology. 132: 272-281.
-
(2007)
Gastroenterology
, vol.132
, pp. 272-281
-
-
Daly, A.K.1
Aithal, G.P.2
Leathart, J.B.3
Swainsbury, R.A.4
Dang, T.S.5
Day, C.P.6
-
37
-
-
1542286160
-
A novel functional polymorphism in the uridine diphosphate-glucuronosyltransferase 2B7 promoter with significant impact on promoter activity
-
Duguay, Y., C. Baar, F. Skorpen, and C. Guillemette. 2004. A novel functional polymorphism in the uridine diphosphate-glucuronosyltransferase 2B7 promoter with significant impact on promoter activity. Clin. Pharmacol. Ther. 75: 223-233.
-
(2004)
Clin. Pharmacol. Ther.
, vol.75
, pp. 223-233
-
-
Duguay, Y.1
Baar, C.2
Skorpen, F.3
Guillemette, C.4
|