The effect of neoadjuvant chemoradiotherapy on whole-body physical fitness and skeletal muscle mitochondrial oxidative phosphorylation in vivo in locally advanced rectal cancer patients - An observational pilot study

PLoS ONE

Volumn 9, Issue 12, 2014, Pages

  West, Malcolm A ^a,b   Loughney, Lisa ^a,c,d   Lythgoe, Daniel ^e   Barben, Christopher P ^a   Adams, Valerie L ^b   Bimson, William E ^b   Grocott, Michael P W ^a,b,c,d,f   Jack, Sandy ^a,b,c,d,f   Kemp, Graham J ^b  

^a ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST   (United Kingdom)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

^c University Hospital Southampton NHS Foundation Trust   (United Kingdom)

^d UNIVERSITY HOSPITAL SOUTHAMPTON NHS FOUNDATION TRUST   (United Kingdom)

^e IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^f UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CAPECITABINE; CREATINE PHOSPHATE;

ADJUVANT CHEMORADIOTHERAPY; ADJUVANT THERAPY; ADVANCED CANCER; AGED; ANAEROBIC METABOLISM; ARTICLE; CARDIOPULMONARY EXERCISE TEST; CLINICAL ARTICLE; DIARRHEA; DRUG DOSE REDUCTION; FEMALE; FITNESS; HUMAN; IN VIVO STUDY; MALE; MITOCHONDRIAL RESPIRATION; MUSCLE EXERCISE; OBSERVATIONAL STUDY; OXIDATIVE PHOSPHORYLATION; OXYGEN CONSUMPTION; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PHYSICAL ACTIVITY; PILOT STUDY; PROSPECTIVE STUDY; QUADRICEPS FEMORIS MUSCLE; RADIATION DERMATITIS; RECTUM CANCER; SKELETAL MUSCLE; CONTROLLED STUDY; EXERCISE TEST; METABOLISM; MIDDLE AGED; MITOCHONDRION; PATHOPHYSIOLOGY; RANDOMIZED CONTROLLED TRIAL; RECTAL NEOPLASMS; TUMOR RECURRENCE; UNITED KINGDOM;

AGED; CHEMORADIOTHERAPY, ADJUVANT; EXERCISE TEST; FEMALE; GREAT BRITAIN; HUMANS; MALE; MIDDLE AGED; MITOCHONDRIA; MUSCLE, SKELETAL; NEOADJUVANT THERAPY; NEOPLASM RECURRENCE, LOCAL; OXIDATIVE PHOSPHORYLATION; PHYSICAL FITNESS; RECTAL NEOPLASMS;

EID: 84918569640     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0111526     Document Type: Article

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