Reduced synaptic vesicle protein degradation at lysosomes curbs TBC1D24/sky-induced neurodegeneration

Journal of Cell Biology

Volumn 207, Issue 4, 2014, Pages 453-462

  Fernandes, Ana Clara ^a   Uytterhoeven, Valerie ^a   Kuenen, Sabine ^a   Wang, Yu Chun ^a   Slabbaert, Jan R ^a   Swerts, Jef ^a   Kasprowicz, Jaroslaw ^a   Aerts, Stein ^a   Verstreken, Patrik ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN; SKYWALKER PROTEIN; TBC1D24 PROTEIN; UNCLASSIFIED DRUG; CARRIER PROTEIN; DEEP ORANGE PROTEIN, DROSOPHILA; DNA BINDING PROTEIN; DROSOPHILA PROTEIN; FM1 43; MEMBRANE PROTEIN; N-SYNAPTOBREVIN PROTEIN, DROSOPHILA; PYRIDINIUM DERIVATIVE; QUATERNARY AMMONIUM DERIVATIVE; RAB PROTEIN; SKYWALKER PROTEIN, DROSOPHILA; SYNAPTOBREVIN; TBC1D24 PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; ENDOSOME; EPILEPSY; FEMALE; LYSOSOME; MENTAL DEFICIENCY; MUTANT; NERVE DEGENERATION; NEUROTRANSMISSION; NONHUMAN; OSTEODYSTROPHY; PROTEIN DEGRADATION; PROTEIN METABOLISM; PROTEIN TARGETING; SYNAPSE VESICLE; SYNAPTIC TRANSMISSION; ANIMAL; BIOSYNTHESIS; CRANIOFACIAL MALFORMATION; DEGENERATIVE DISEASE; GENETICS; HAND MALFORMATION; HUMAN; INTELLECTUAL IMPAIRMENT; METABOLISM; MUTATION; NAIL DISEASE; NEUROMUSCULAR SYNAPSE; PERCEPTION DEAFNESS; PHYSIOLOGY; PROTEIN TRANSPORT;

DROSOPHILA MELANOGASTER;

ANIMALS; CARRIER PROTEINS; CRANIOFACIAL ABNORMALITIES; DNA-BINDING PROTEINS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; ENDOSOMES; HAND DEFORMITIES, CONGENITAL; HEARING LOSS, SENSORINEURAL; HUMANS; INTELLECTUAL DISABILITY; LYSOSOMES; MEMBRANE GLYCOPROTEINS; MUTATION; NAILS, MALFORMED; NEURODEGENERATIVE DISEASES; NEUROMUSCULAR JUNCTION; PROTEIN TRANSPORT; PROTEOLYSIS; PYRIDINIUM COMPOUNDS; QUATERNARY AMMONIUM COMPOUNDS; R-SNARE PROTEINS; RAB GTP-BINDING PROTEINS; RAB5 GTP-BINDING PROTEINS; SYNAPTIC TRANSMISSION; SYNAPTIC VESICLES;

EID: 84918565878     PISSN: 00219525     EISSN: 15408140     Source Type: Journal    
DOI: 10.1083/jcb.201406026     Document Type: Article

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