메뉴 건너뛰기




Volumn 5, Issue SEP, 2014, Pages

EPO mediates neurotrophic, neuroprotective, anti-oxidant, and anti-apoptotic effects via downregulation of miR-451 and miR-885-5p in SH-SY5Y neuron-like cells

Author keywords

Apoptosis; Cell death; Erythropoietin; Migration; MiRNAs; Neurite outgrowth; Oxidative stress; Proliferation

Indexed keywords

ANTIOXIDANT; CYCLIN DEPENDENT KINASE 2; ERYTHROPOIETIN; ERYTHROPOIETIN RECEPTOR; GALANIN; MATRIX METALLO PEPTIDASE 9; MICRORNA; MINICHROMOSOME MAINTENANCE PROTEIN 5; MIR 451; MIR 885 5P; PEPTIDASE; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; VASCULOTROPIN A;

EID: 84918542258     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2014.00475     Document Type: Article
Times cited : (46)

References (44)
  • 1
    • 84886629827 scopus 로고    scopus 로고
    • Physiology and pharmacology of erythropoietin
    • Jelkmann W. Physiology and pharmacology of erythropoietin. Transfus Med Hemother (2013) 40(5):302-9. doi: 10.1159/000356193
    • (2013) Transfus Med Hemother , vol.40 , Issue.5 , pp. 302-309
    • Jelkmann, W.1
  • 2
    • 79960930497 scopus 로고    scopus 로고
    • Erythropoietin in neonatal brain protection: the past, the present and the future
    • Kumral A, Tüzün F, Oner MG, Genç S, Duman N, Ozkan H. Erythropoietin in neonatal brain protection: the past, the present and the future. Brain Dev (2011) 33(8):632-43. doi:10.1016/j.braindev.2010.10.014
    • (2011) Brain Dev , vol.33 , Issue.8 , pp. 632-643
    • Kumral, A.1    Tüzün, F.2    Oner, M.G.3    Genç, S.4    Duman, N.5    Ozkan, H.6
  • 3
    • 84882741604 scopus 로고    scopus 로고
    • Epo and non-hematopoietic cells: what do we know?
    • Ogunshola OO, Bogdanova AY. Epo and non-hematopoietic cells: what do we know? Methods Mol Biol (2013) 982:13-41. doi:10.1007/978-1-62703-308-4_2
    • (2013) Methods Mol Biol , vol.982 , pp. 13-41
    • Ogunshola, O.O.1    Bogdanova, A.Y.2
  • 4
    • 0034641710 scopus 로고    scopus 로고
    • Erythropoietin crosses the blood-brain barrier to protect against experimental brain injury
    • Brines ML, Ghezzi P, Keenan S, Agnello D, de Lanerolle NC, Cerami C, et al. Erythropoietin crosses the blood-brain barrier to protect against experimental brain injury. Proc Natl Acad Sci U S A (2000) 97(19):10526-31. doi:10.1073/pnas.97.19.10526
    • (2000) Proc Natl Acad Sci U S A , vol.97 , Issue.19 , pp. 10526-10531
    • Brines, M.L.1    Ghezzi, P.2    Keenan, S.3    Agnello, D.4    de Lanerolle, N.C.5    Cerami, C.6
  • 5
    • 1842610133 scopus 로고    scopus 로고
    • Erythropoietin and the nervous system
    • Genc S, Koroglu TF, Genc K. Erythropoietin and the nervous system. Brain Res (2004) 1000(1-2):19-31. doi:10.1016/j.brainres.2003.12.037
    • (2004) Brain Res , vol.1000 , Issue.1-2 , pp. 19-31
    • Genc, S.1    Koroglu, T.F.2    Genc, K.3
  • 6
    • 78649668528 scopus 로고    scopus 로고
    • Erythropoietin as neuroprotective and neuroregenerative treatment strategy: comprehensive overview of 12 years of preclinical and clinical research
    • Sargin D, Friedrichs H, El-Kordi A, Ehrenreich H. Erythropoietin as neuroprotective and neuroregenerative treatment strategy: comprehensive overview of 12 years of preclinical and clinical research. Best Pract Res Clin Anaesthesiol (2010) 24(4):573-94. doi:10.1016/j.bpa.2010.10.005
    • (2010) Best Pract Res Clin Anaesthesiol , vol.24 , Issue.4 , pp. 573-594
    • Sargin, D.1    Friedrichs, H.2    El-Kordi, A.3    Ehrenreich, H.4
  • 7
    • 84866950150 scopus 로고    scopus 로고
    • Erythropoietin: new directions for the nervous system
    • Maiese K, Chong ZZ, Shang YC, Wang S. Erythropoietin: new directions for the nervous system. Int J Mol Sci (2012) 13(9):11102-29. doi:10.3390/ijms130911102
    • (2012) Int J Mol Sci , vol.13 , Issue.9 , pp. 11102-11129
    • Maiese, K.1    Chong, Z.Z.2    Shang, Y.C.3    Wang, S.4
  • 8
    • 84877871472 scopus 로고    scopus 로고
    • Targeting erythropoietin for chronic neurodegenerative diseases
    • Chong ZZ, Shang YC, Mu Y, Cui S, Yao Q, Maiese K. Targeting erythropoietin for chronic neurodegenerative diseases. Expert Opin Ther Targets (2013) 17(6):707-20. doi:10.1517/14728222.2013.780599
    • (2013) Expert Opin Ther Targets , vol.17 , Issue.6 , pp. 707-720
    • Chong, Z.Z.1    Shang, Y.C.2    Mu, Y.3    Cui, S.4    Yao, Q.5    Maiese, K.6
  • 10
    • 43249122718 scopus 로고    scopus 로고
    • Recombinant erythropoietin is neuroprotective in a novel mouse oxidative Injury model
    • Juul SE, McPherson RJ, Bammler TK, Wilkerson J, Beyer RP, Farin FM. Recombinant erythropoietin is neuroprotective in a novel mouse oxidative Injury model. Dev Neurosci (2008) 30(4):231-42. doi:10.1159/000110348
    • (2008) Dev Neurosci , vol.30 , Issue.4 , pp. 231-242
    • Juul, S.E.1    McPherson, R.J.2    Bammler, T.K.3    Wilkerson, J.4    Beyer, R.P.5    Farin, F.M.6
  • 11
    • 69049113908 scopus 로고    scopus 로고
    • Microarray analysis of high-dose recombinant erythropoietin treatment of unilateral brain injury in neonatal mouse hippocampus
    • Juul SE, Beyer RP, Bammler TK, McPherson RJ, Wilkerson J, Farin FM. Microarray analysis of high-dose recombinant erythropoietin treatment of unilateral brain injury in neonatal mouse hippocampus. Pediatr Res (2009) 65(5):485-92. doi:10.1203/PDR.0b013e31819d90c8
    • (2009) Pediatr Res , vol.65 , Issue.5 , pp. 485-492
    • Juul, S.E.1    Beyer, R.P.2    Bammler, T.K.3    McPherson, R.J.4    Wilkerson, J.5    Farin, F.M.6
  • 12
    • 0037178664 scopus 로고    scopus 로고
    • Cerebral transcriptome analysis of transgenic mice overexpressing erythropoietin
    • Maurer MH, Frietsch T, Waschke KF, Kuschinsky W. Cerebral transcriptome analysis of transgenic mice overexpressing erythropoietin. Neurosci Lett (2002) 327(3):181-4. doi:10.1016/S0304-3940(02)00425-1
    • (2002) Neurosci Lett , vol.327 , Issue.3 , pp. 181-184
    • Maurer, M.H.1    Frietsch, T.2    Waschke, K.F.3    Kuschinsky, W.4
  • 13
    • 84862201617 scopus 로고    scopus 로고
    • Erythropoietin-induced changes in brain gene expression reveal induction of synaptic plasticity genes in experimental stroke
    • Mengozzi M, Cervellini I, Villa P, Erbayraktar Z, Gökmen N, Yilmaz O, et al. Erythropoietin-induced changes in brain gene expression reveal induction of synaptic plasticity genes in experimental stroke. Proc Natl Acad Sci U S A (2012) 109(24):9617-22. doi:10.1073/pnas.1200554109
    • (2012) Proc Natl Acad Sci U S A , vol.109 , Issue.24 , pp. 9617-9622
    • Mengozzi, M.1    Cervellini, I.2    Villa, P.3    Erbayraktar, Z.4    Gökmen, N.5    Yilmaz, O.6
  • 14
    • 84918510415 scopus 로고    scopus 로고
    • Comparison of the effects of erythropoietin and anakinra on functional recovery and gene expression in a traumatic brain injury model
    • Anderson GD, Peterson TC, VonderHaar C, Kantor ED, Farin FM, Bammler TK, et al. Comparison of the effects of erythropoietin and anakinra on functional recovery and gene expression in a traumatic brain injury model. Front Pharmacol (2013) 4:129. doi:10.3389/fphar.2013.00129
    • (2013) Front Pharmacol , vol.4 , pp. 129
    • Anderson, G.D.1    Peterson, T.C.2    VonderHaar, C.3    Kantor, E.D.4    Farin, F.M.5    Bammler, T.K.6
  • 15
    • 84934444851 scopus 로고    scopus 로고
    • The role of microRNAs in biological processes
    • Tüfekci KU, Meuwissen RL, Genç S. The role of microRNAs in biological processes. Methods Mol Biol (2014) 1107:15-31. doi:10.1007/978-1-62703-748-8_2
    • (2014) Methods Mol Biol , vol.1107 , pp. 15-31
    • Tüfekci, K.U.1    Meuwissen, R.L.2    Genç, S.3
  • 16
    • 0027751663 scopus 로고
    • The C. elegansheterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • Lee RC, Feinbaum RL, Ambros V. The C. elegansheterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell (1993) 75(5):843-54. doi:10.1016/0092-8674(93)90529-Y
    • (1993) Cell , vol.75 , Issue.5 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 17
    • 84893567085 scopus 로고    scopus 로고
    • MicroRNAs in brain development and function: a matter of flexibility and stability
    • Follert P, Cremer H, Béclin C. MicroRNAs in brain development and function: a matter of flexibility and stability. Front Mol Neurosci (2014) 7:5. doi:10.3389/fnmol.2014.00005
    • (2014) Front Mol Neurosci , vol.7 , pp. 5
    • Follert, P.1    Cremer, H.2    Béclin, C.3
  • 18
    • 47249165678 scopus 로고    scopus 로고
    • Identification of erythropoietin-induced microRNAs in haematopoietic cells during erythroid differentiation
    • Kosaka N, Sugiura K, Yamamoto Y, Yoshioka Y, Miyazaki H, Komatsu N, et al. Identification of erythropoietin-induced microRNAs in haematopoietic cells during erythroid differentiation. Br J Haematol (2008) 142(2):293-300. doi:10.1111/j.1365-2141.2008.07151.x
    • (2008) Br J Haematol , vol.142 , Issue.2 , pp. 293-300
    • Kosaka, N.1    Sugiura, K.2    Yamamoto, Y.3    Yoshioka, Y.4    Miyazaki, H.5    Komatsu, N.6
  • 19
    • 77149132365 scopus 로고    scopus 로고
    • Multiple sclerosis: microRNA expression profiles accurately Differentiate patients with relapsing-remitting disease from healthy controls
    • Keller A, Leidinger P, Lange J, Borries A, Schroers H, Scheffler M, et al. Multiple sclerosis: microRNA expression profiles accurately Differentiate patients with relapsing-remitting disease from healthy controls. PLoS One (2009) 4(10):e7440. doi:10.1371/journal.pone.0007440
    • (2009) PLoS One , vol.4 , Issue.10
    • Keller, A.1    Leidinger, P.2    Lange, J.3    Borries, A.4    Schroers, H.5    Scheffler, M.6
  • 20
    • 33645762226 scopus 로고
    • A sharper Bonferroni procedure for multiple tests of significance
    • Hochberg Y. A sharper Bonferroni procedure for multiple tests of significance. Biometrica (1988) 75:185-93. doi:10.1093/biomet/75.4.800
    • (1988) Biometrica , vol.75 , pp. 185-193
    • Hochberg, Y.1
  • 21
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: a practical and powerful approach to multiple testing
    • Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc B (1995) 57:289-300.
    • (1995) J R Stat Soc B , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 22
    • 44949231424 scopus 로고    scopus 로고
    • Analyzing real-time PCR data by the comparative C(T) method
    • Schmittgen TD, Livak KJ. Analyzing real-time PCR data by the comparative C(T) method. Nat Protoc (2008) 3(6):1101-8. doi:10.1038/nprot.2008.73
    • (2008) Nat Protoc , vol.3 , Issue.6 , pp. 1101-1108
    • Schmittgen, T.D.1    Livak, K.J.2
  • 23
    • 78651266827 scopus 로고    scopus 로고
    • miRTarBase: a database curates experimentally validated microRNA-target interactions
    • Hsu SD, Lin FM, Wu WY, Liang C, Huang WC, Chan WL, et al. miRTarBase: a database curates experimentally validated microRNA-target interactions. Nucleic Acids Res (2011) 39:D163-9. doi:10.1093/nar/gkq1107
    • (2011) Nucleic Acids Res , vol.39 , pp. D163-D169
    • Hsu, S.D.1    Lin, F.M.2    Wu, W.Y.3    Liang, C.4    Huang, W.C.5    Chan, W.L.6
  • 24
  • 25
    • 79851505266 scopus 로고    scopus 로고
    • Reactome knowledgebase of human biological pathways and processes
    • D'Eustachio P. Reactome knowledgebase of human biological pathways and processes. Methods Mol Biol (2011) 694:49-61. doi:10.1007/978-1-60761-977-2_4
    • (2011) Methods Mol Biol , vol.694 , pp. 49-61
    • D'Eustachio, P.1
  • 26
    • 84862162820 scopus 로고    scopus 로고
    • The receptor that tames the innate immune response
    • Brines M, Cerami A. The receptor that tames the innate immune response. Mol Med (2012) 18:486-96. doi:10.2119/molmed.2011.00414
    • (2012) Mol Med , vol.18 , pp. 486-496
    • Brines, M.1    Cerami, A.2
  • 27
    • 84856317888 scopus 로고    scopus 로고
    • The pleiotropic effects of erythropoietin in infection and inflammation
    • Nairz M, Sonnweber T, Schroll A, Theurl I, Weiss G. The pleiotropic effects of erythropoietin in infection and inflammation. Microbes Infect (2012) 14(3):238-46. doi:10.1016/j.micinf.2011.10.005
    • (2012) Microbes Infect , vol.14 , Issue.3 , pp. 238-246
    • Nairz, M.1    Sonnweber, T.2    Schroll, A.3    Theurl, I.4    Weiss, G.5
  • 28
    • 33644974691 scopus 로고    scopus 로고
    • Effect of erythropoietin on staurosporine-induced apoptosis and differentiation of SH-SY5Y neuroblastoma cells
    • Pregi N, Vittori D, Pérez G, Leirós CP, Nesse A. Effect of erythropoietin on staurosporine-induced apoptosis and differentiation of SH-SY5Y neuroblastoma cells. Biochim Biophys Acta (2006) 1763(2):238-46. doi:10.1016/j.bbamcr.2005.12.011
    • (2006) Biochim Biophys Acta , vol.1763 , Issue.2 , pp. 238-246
    • Pregi, N.1    Vittori, D.2    Pérez, G.3    Leirós, C.P.4    Nesse, A.5
  • 29
    • 33846239262 scopus 로고    scopus 로고
    • A "classical" homodimeric erythropoietin receptor is essential for the antiapoptotic effects of erythropoietin on differentiated neuroblastoma SH-SY5Y and pheochromocytoma PC-12 cells
    • Um M, Gross AW, Lodish HF. A "classical" homodimeric erythropoietin receptor is essential for the antiapoptotic effects of erythropoietin on differentiated neuroblastoma SH-SY5Y and pheochromocytoma PC-12 cells. Cell Signal (2007) 19(3):634-45. doi:10.1016/j.cellsig.2006.08.014
    • (2007) Cell Signal , vol.19 , Issue.3 , pp. 634-645
    • Um, M.1    Gross, A.W.2    Lodish, H.F.3
  • 30
    • 84875843238 scopus 로고    scopus 로고
    • Protective action of erythropoietin on neuronal damage induced by activated microglia
    • Wenker SD, Chamorro ME, Vittori DC, Nesse AB. Protective action of erythropoietin on neuronal damage induced by activated microglia. FEBS J (2013) 280(7):1630-42. doi:10.1111/febs.12172
    • (2013) FEBS J , vol.280 , Issue.7 , pp. 1630-1642
    • Wenker, S.D.1    Chamorro, M.E.2    Vittori, D.C.3    Nesse, A.B.4
  • 31
    • 84877285234 scopus 로고    scopus 로고
    • Neuroprotective effects of microRNA-210 against oxygen-glucose deprivation through inhibition of apoptosis in PC12 cells
    • Qiu J, Zhou XY, Zhou XG, Cheng R, Liu HY, Li Y. Neuroprotective effects of microRNA-210 against oxygen-glucose deprivation through inhibition of apoptosis in PC12 cells. Mol Med Rep (2013) 7(6):1955-9. doi:10.3892/mmr.2013.1431
    • (2013) Mol Med Rep , vol.7 , Issue.6 , pp. 1955-1959
    • Qiu, J.1    Zhou, X.Y.2    Zhou, X.G.3    Cheng, R.4    Liu, H.Y.5    Li, Y.6
  • 32
    • 84891746974 scopus 로고    scopus 로고
    • MicroRNA-210 overexpression induces angiogenesis and neurogenesis in the normal adult mouse brain
    • Zeng L, He X, Wang Y, Tang Y, Zheng C, Cai H, et al. MicroRNA-210 overexpression induces angiogenesis and neurogenesis in the normal adult mouse brain. Gene Ther (2014) 21(1):37-43. doi:10.1038/gt.2013.55
    • (2014) Gene Ther , vol.21 , Issue.1 , pp. 37-43
    • Zeng, L.1    He, X.2    Wang, Y.3    Tang, Y.4    Zheng, C.5    Cai, H.6
  • 33
    • 84859748623 scopus 로고    scopus 로고
    • An activity-regulated microRNA, miR-188, controls dendritic plasticity and synaptic transmission by downregulating neuropilin-2
    • Lee K, Kim JH, Kwon OB, An K, Ryu J, Cho K, et al. An activity-regulated microRNA, miR-188, controls dendritic plasticity and synaptic transmission by downregulating neuropilin-2. J Neurosci (2012) 32(16):5678-87. doi:10.1523/JNEUROSCI.6471-11.2012
    • (2012) J Neurosci , vol.32 , Issue.16 , pp. 5678-5687
    • Lee, K.1    Kim, J.H.2    Kwon, O.B.3    An, K.4    Ryu, J.5    Cho, K.6
  • 34
    • 85008256418 scopus 로고    scopus 로고
    • Erythropoietin markedly attenuates brain infarct size and improves neurological function in the rat
    • Yuen CM, Leu S, Lee FY, Yen CH, Lin YC, Chua S, et al. Erythropoietin markedly attenuates brain infarct size and improves neurological function in the rat. J Investig Med (2010) 58(7):893-904. doi:10.231/JIM.0b013e3181e80c40
    • (2010) J Investig Med , vol.58 , Issue.7 , pp. 893-904
    • Yuen, C.M.1    Leu, S.2    Lee, F.Y.3    Yen, C.H.4    Lin, Y.C.5    Chua, S.6
  • 35
  • 36
    • 79952262410 scopus 로고    scopus 로고
    • Galanin acts as a trophic factor to the central and peripheral nervous systems
    • Hobson SA, Bacon A, Elliot-Hunt CR, Holmes FE, Kerr NC, Pope R, et al. Galanin acts as a trophic factor to the central and peripheral nervous systems. EXS (2010) 102:25-38. doi:10.1007/s00018-008-8154-7
    • (2010) EXS , vol.102 , pp. 25-38
    • Hobson, S.A.1    Bacon, A.2    Elliot-Hunt, C.R.3    Holmes, F.E.4    Kerr, N.C.5    Pope, R.6
  • 37
    • 84897945252 scopus 로고    scopus 로고
    • Definition of a family of tissue-protective cytokines using functional cluster analysis: a proof-of-concept study
    • Mengozzi M, Ermilov P, Annenkov A, Ghezzi P, Pearl F. Definition of a family of tissue-protective cytokines using functional cluster analysis: a proof-of-concept study. Front Immunol (2014) 5:115. doi:10.3389/fimmu.2014.00115
    • (2014) Front Immunol , vol.5 , pp. 115
    • Mengozzi, M.1    Ermilov, P.2    Annenkov, A.3    Ghezzi, P.4    Pearl, F.5
  • 38
    • 84890408530 scopus 로고    scopus 로고
    • Erythropoietin improves motor and cognitive deficit, axonal pathology, and neuroinflammation in a combined model of diffuse traumatic brain injury and hypoxia, in association with upregulation of the erythropoietin receptor
    • Hellewell SC, Yan EB, Alwis DS, Bye N, Morganti-Kossmann MC. Erythropoietin improves motor and cognitive deficit, axonal pathology, and neuroinflammation in a combined model of diffuse traumatic brain injury and hypoxia, in association with upregulation of the erythropoietin receptor. J Neuroinflammation (2013) 10:156. doi:10.1186/1742-2094-10-156
    • (2013) J Neuroinflammation , vol.10 , pp. 156
    • Hellewell, S.C.1    Yan, E.B.2    Alwis, D.S.3    Bye, N.4    Morganti-Kossmann, M.C.5
  • 39
    • 79955836048 scopus 로고    scopus 로고
    • MicroRNA miR-885-5p targets CDK2 and MCM5, activates p53 and Inhibits proliferation and survival
    • Afanasyeva EA, Mestdagh P, Kumps C, Vandesompele J, Ehemann V, Theissen J, et al. MicroRNA miR-885-5p targets CDK2 and MCM5, activates p53 and Inhibits proliferation and survival. Cell Death Differ (2011) 18(6):974-84. doi:10.1038/cdd.2010.164
    • (2011) Cell Death Differ , vol.18 , Issue.6 , pp. 974-984
    • Afanasyeva, E.A.1    Mestdagh, P.2    Kumps, C.3    Vandesompele, J.4    Ehemann, V.5    Theissen, J.6
  • 40
    • 84886150597 scopus 로고    scopus 로고
    • miR-125b targets erythropoietin and its receptor and their expression correlates with metastatic potential and ERBB2/HER2 expression
    • Ferracin M, Bassi C, Pedriali M, Pagotto S, D'Abundo L, Zagatti B, et al. miR-125b targets erythropoietin and its receptor and their expression correlates with metastatic potential and ERBB2/HER2 expression. Mol Cancer (2013) 12(1):130. doi:10.1186/1476-4598-12-130
    • (2013) Mol Cancer , vol.12 , Issue.1 , pp. 130
    • Ferracin, M.1    Bassi, C.2    Pedriali, M.3    Pagotto, S.4    D'Abundo, L.5    Zagatti, B.6
  • 41
    • 84875050771 scopus 로고    scopus 로고
    • Cross-talk between microRNAs, nuclear factor E2-related factor 2, and heme oxygenase-1 in ochratoxin A-induced toxic effects in renal proximal tubular epithelial cells
    • Stachurska A, Ciesla M, Kozakowska M, Wolffram S, Boesch-Saadatmandi C, Rimbach G, et al. Cross-talk between microRNAs, nuclear factor E2-related factor 2, and heme oxygenase-1 in ochratoxin A-induced toxic effects in renal proximal tubular epithelial cells. Mol Nutr Food Res (2013) 57(3):504-15. doi:10.1002/mnfr.201200456
    • (2013) Mol Nutr Food Res , vol.57 , Issue.3 , pp. 504-515
    • Stachurska, A.1    Ciesla, M.2    Kozakowska, M.3    Wolffram, S.4    Boesch-Saadatmandi, C.5    Rimbach, G.6
  • 42
    • 84877809493 scopus 로고    scopus 로고
    • Signaling pathways of Cell proliferation are involved in the differential effect of erythropoietin and Its carbamylated derivative
    • Chamorro ME, Wenker SD, Vota DM, Vittori DC, Nesse AB. Signaling pathways of Cell proliferation are involved in the differential effect of erythropoietin and Its carbamylated derivative. Biochim Biophys Acta (2013) 1833(8):1960-8. doi:10.1016/j.bbamcr.2013.04.006
    • (2013) Biochim Biophys Acta , vol.1833 , Issue.8 , pp. 1960-1968
    • Chamorro, M.E.1    Wenker, S.D.2    Vota, D.M.3    Vittori, D.C.4    Nesse, A.B.5
  • 43
    • 84869212180 scopus 로고    scopus 로고
    • Exosomal miRNAs: biological properties and therapeutic potential
    • Hu G, Drescher KM, Chen XM. Exosomal miRNAs: biological properties and therapeutic potential. Front Genet (2012) 3:56. doi:10.3389/fgene.2012.00056
    • (2012) Front Genet , vol.3 , pp. 56
    • Hu, G.1    Drescher, K.M.2    Chen, X.M.3
  • 44
    • 84880341728 scopus 로고    scopus 로고
    • More than cell dust: microparticles isolated from cerebrospinal fluid of brain injured patients are messengers carrying mRNAs, miRNAs, and proteins
    • Patz S, Trattnig C, Grünbacher G, Ebner B, Gülly C, Novak A, et al. More than cell dust: microparticles isolated from cerebrospinal fluid of brain injured patients are messengers carrying mRNAs, miRNAs, and proteins. J Neurotrauma (2013) 30(14):1232-42. doi:10.1089/neu.2012.2596
    • (2013) J Neurotrauma , vol.30 , Issue.14 , pp. 1232-1242
    • Patz, S.1    Trattnig, C.2    Grünbacher, G.3    Ebner, B.4    Gülly, C.5    Novak, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.