Melanopsin mediates light-dependent relaxation in blood vessels

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 50, 2014, Pages 17977-17982

  Sikka, Gautam ^a   Hussmann, G Patrick ^a   Pandey, Deepesh ^a   Cao, Suyi ^a   Hori, Daijiro ^a   Park, Jong Taek ^a   Steppan, Jochen ^a   Kim, Jae Hyung ^a   Barodka, Viachaslau ^a   Myers, Allen C ^b   Santhanam, Lakshmi ^a,c   Nyhan, Daniel ^a   Halushka, Marc K ^a   Koehler, Raymond C ^a   Snyder, Solomon H ^a   Shimoda, Larissa A ^a   Berkowitz, Dan E ^a,c  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c Johns Hopkins University   (United States)

Author keywords

GRK2; Melanopsin; Opsin; Photorelaxation; Signal transduction

Indexed keywords

CARBON MONOXIDE; CYCLIC GMP DEPENDENT PROTEIN KINASE; CYTOCHROME P450; G PROTEIN COUPLED RECEPTOR KINASE 2; GUANYLATE CYCLASE; MELANOPSIN; NITRIC OXIDE; PHOSPHODIESTERASE VI; ADRBK1 PROTEIN, MOUSE; CYCLIC GMP; SCOTOPSIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERY BLOOD FLOW; ARTERY DILATATION; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; EX VIVO STUDY; GENE EXPRESSION PROFILING; HYPERPOLARIZATION; INTRACELLULAR MEMBRANE; MEMBRANE POTENTIAL; MOUSE; MYOGRAPHY; NONHUMAN; PHOTORELAXATION; PHOTOSTIMULATION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; TAIL ARTERY; VASODILATATION; ANIMAL; BLOOD VESSEL; LASER DOPPLER FLOWMETRY; LIGHT; METABOLISM; PHYSIOLOGY; RADIATION RESPONSE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALIA; MUS;

ANIMALS; BLOOD VESSELS; BLOTTING, WESTERN; CYCLIC GMP; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 6; G-PROTEIN-COUPLED RECEPTOR KINASE 2; LASER-DOPPLER FLOWMETRY; LIGHT; MICE; MYOGRAPHY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; ROD OPSINS; SIGNAL TRANSDUCTION; VASODILATION;

EID: 84918499526     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1420258111     Document Type: Article

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